Abstract:
:Multiple intravenous injections of contrast media are used in radiology, but information regarding corresponding changes in the serum iodine concentrations and osmolality is lacking. We measured the changes in serum iodine concentration and serum osmolality in rabbits after a series of intravenous injections of contrast media. Hypaque-76 (1 cc/kg) was injected intravenously in awake rabbits at 10-minute intervals for 1 hour and arterial blood sampled at midpoint times between injections. During the 1-hour period of seven serial injections, mean serum iodine concentration at 5 minutes was 2.3 mg I/cc (+/- 0.1 SEM, n = 14); at 35 minutes, 5.1 mg I/cc (+/- 0.2); and at 65 minutes, 6.7 mg I/cc (+/- 0.4). The mean peak concentration was 6.8 mg I/cc (+/- 0.4). Serum osmolality underwent a mean increase of 16 mosm/kg during the injection period. Hypertonic mannitol injections produced a smaller increase in osmolality (10 mosm/kg). Isotonic saline injections in control animals produced no change in osmolality.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Rubin DI,Kido DK,Morris TW,Fischer HWdoi
10.1097/00004424-198703000-00007subject
Has Abstractpub_date
1987-03-01 00:00:00pages
223-6issue
3eissn
0020-9996issn
1536-0210journal_volume
22pub_type
杂志文章abstract:OBJECTIVES:Comparison of intravenous Fenestra VC-enhanced computed tomography (CT) with gadopentetate dimeglumine and Ferucarbotran contrast-enhanced magnetic resonance imaging (MRI) for the in vivo imaging of hepatic ischemia/reperfusion injury (IRI) in a murine model. MATERIAL AND METHODS:After induction of hepatic ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318155aa2e
更新日期:2008-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000116125.96544.64
更新日期:2004-03-01 00:00:00
abstract::A method is presented for selective catheterization and filming of the small internal spermatic and proper hepatic arteries in rabbits. The angiograms thus obtained afford clear delineation of the vessels and their branches and can enhance radiographic investigation of a variety of experimental disease models. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197705000-00009
更新日期:1977-05-01 00:00:00
abstract::Sixteen observers averaging 7.4 years experience in interpreting radiology images and 16 observers without radiology training were tested for their ability to detect low-contrast signals in structured noise backgrounds using a digital display system. No significant difference in true positives, false positives, time t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198704000-00006
更新日期:1987-04-01 00:00:00
abstract::The cytogenetic interactions of ionic (diatrizoate, ioxaglate) and nonionic (iohexol) contrast media (CM) with antineoplastic drugs cyclophosphamide (CPA) and carmustine (CARM) were evaluated in a rat bone marrow cell model. Male Wistar rats were anesthetized with a 6% chloral hydrate solution and divided into five gr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198805000-00011
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVES:To test the feasibility of combining inner-volume imaging (IVI) techniques with conventional multishot periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) techniques for targeted-PROPELLER magnetic resonance imaging. MATERIALS AND METHODS:Perpendicular section-selective ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181a8b015
更新日期:2009-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria. METHODS:The device consists of a symmetrical cage of six superelastic monofile wires, including a mic...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199702000-00003
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000163743.63063.9f
更新日期:2005-06-01 00:00:00
abstract::Using simple surgical techniques, experimental carotid aneurysms are created which simulate some types of human berry aneurysms, both in hemodynamic and radiographic behavior. End to side anastomoses of an external jugular vein graft to the common carotid artery can be carried out by radiologic personnel with no forma...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197703000-00009
更新日期:1977-03-01 00:00:00
abstract:PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000195836.57778.1f
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS:Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000383
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199306000-00011
更新日期:1993-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the potential of iterative metal artifact reduction (IMAR) for the improvement of computed tomography (CT)-based position emission tomography (PET) attenuation correction in the vicinity of metal implants and compare it with dual-energy-based metal artifact reduction stra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000306
更新日期:2017-01-01 00:00:00
abstract::We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198904000-00008
更新日期:1989-04-01 00:00:00
abstract::Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198403000-00007
更新日期:1984-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199903000-00014
更新日期:1999-03-01 00:00:00
abstract::In order to measure the accuracy of a diagnostic imaging technique, the correctness of each observer decision must be determined. This is often difficult in clinical cases, and various strategies are frequently used to approximate the truth. Experiments using chest radiographs as an example are reported to show the pi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198303000-00018
更新日期:1983-03-01 00:00:00
abstract:OBJECTIVES:We sought to assess large bowel motility, induced by 2 prokinetic agents, senna tea and erythromycin, using functional cine magnetic resonance imaging (MRI). MATERIALS AND METHODS:Twelve volunteers underwent functional cine MRI before and after the administration of senna tea or erythromycin. The protocol c...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000183054.43131.a8
更新日期:2005-11-01 00:00:00
abstract::Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac oste...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197511000-00008
更新日期:1975-11-01 00:00:00
abstract::Patients with intracranial arteriovenous malformations (AVM) can expect significant mortality (15% to 20%) and morbidity (20% to 30%) over a 15-year to 20-year period. Recent advances in interventional neuroradiology, neurosurgery, neuroanesthesia, and stereotactic radiotherapy provide the opportunity to obliterate ma...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/00004424-199008000-00014
更新日期:1990-08-01 00:00:00
abstract::Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198103000-00006
更新日期:1981-03-01 00:00:00
abstract::Perfluoroctylbromide (PFOB), a radiopaque reticuloendothelial system contrast media for computed tomography, has been shown to accumulate in macrophages. In the current study PFOB was tested in rabbits as an abscess imaging agent. Two abscesses were induced in each of 24 rabbits, one in the liver and the other in the ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198409000-00017
更新日期:1984-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS:Ten pat...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000381
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/01.rli.0000236992.21065.04
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000067491.31978.1c
更新日期:2003-08-01 00:00:00
abstract::A feasibility study is described to provide quantitative texture measures to distinguish between normal lung, alveolar infiltrates and interstitial infiltrates. Advanced computer imaging technology and decision making processes were applied to distinguish between these textural patterns. The results, based on computer...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197807000-00005
更新日期:1978-07-01 00:00:00
abstract::Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/00004424-199911000-00004
更新日期:1999-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To test noninvasive inductive heating of implanted vascular stents as an alternative approach for reduction or prevention of neointimal hyperplasia. METHODS:Calorimetric pretests were performed to get an orientation on the different parameters of influence for inductive heating of stents. The ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000117881.42422.72
更新日期:2004-05-01 00:00:00
abstract::The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198707000-00004
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000285
更新日期:2016-10-01 00:00:00