Abstract:
:Intravenous or intra-aortic injections of meglumine iothalamate in dogs indicate a slightly different tissue distribution and excretory pattern of the meglumine cation and the iothalamate anion. Differences in serum and urinary concentrations of these ions suggest some cellular penetration of the meglumine anion. In addition, there seems to be some evidence for both tubular absorption and tubular excretion of meglumine as a minor component in the renal excretion of this ion. No significant differences could be demonstrated for either urinary load or concentration when the sodium salts of iothalamate were compared to the methylglucamine salts.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Lasser EC,Lang JH,Hamblin AE,Rosen Ldoi
10.1097/00004424-197507000-00004keywords:
subject
Has Abstractpub_date
1975-07-01 00:00:00pages
307-13issue
4eissn
0020-9996issn
1536-0210journal_volume
10pub_type
杂志文章abstract::Thirty patients [four normals, eight with mild and 18 with severe coronary artery disease (CAD)] were studied to evaluate left ventricular function type and post coronary angiography. The end diastolic volume (EDV), end systolic volume (ESV), ejection fraction (EF) and the regional contractility fractions (RCF) of eig...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197603000-00009
更新日期:1976-03-01 00:00:00
abstract:OBJECTIVES:Thermal dose in tumor tissue is a key factor for regional hyperthermia (HT) combined with chemotherapy and for drug delivery using thermosensitive liposomes (TSL). It influences therapy outcome, affects the accumulation of liposomes, and triggers the content release from TSL in the target tissue. For the dev...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31818768cd
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the effects of gadolinium (Gd3+), provided as gadolinium chloride, on fibroblast function. MATERIALS AND METHODS:Human dermal fibroblasts in monolayer culture and intact skin in organ culture were exposed to the lanthanide metal (1-20 μM). RESULTS:Increased proliferat...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181e943d2
更新日期:2010-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199701000-00011
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of an 80-kVp protocol using a moderate concentration contrast material (MC-CM) for cerebral computed tomography angiography by comparison with a conventional 120-kVp protocol using a high concentration contrast material (HC-CM). MATERIALS AND METHODS:Attenuation values and sign...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31823076a4
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the gadolinium (Gd) concentration remaining in human bone tissue after administration of standard clinical doses of 2 Gd-based contrast agents: ProHance and Omniscan. MATERIALS AND METHODS:After administration of 0.1 mmol/kg of Gd chelate to patients undergoing hi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000186569.32408.95
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31827b711e
更新日期:2013-03-01 00:00:00
abstract::Advances in the field of magnetic resonance (MR) as it pertains to clinical diagnostic radiology are examined in this review on the basis of publications in Investigative Radiology over the past 2 years (2005-2006). The articles published during that timeframe are discussed, organizationally wise, by anatomic region w...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/01.rli.0000250461.03245.5c
更新日期:2006-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To present the results of two studies conducted to evaluate the pharmacokinetics and safety of iomeprol in healthy volunteers and in patients with various degrees of renal impairment. METHODS:In these two open-label, single-dose, phase I studies, a 50-mL dose of iomeprol 400 was administered i...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/00004424-200106000-00002
更新日期:2001-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199509000-00004
更新日期:1995-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Tissue contrast phenomenology was investigated analytically and clinically for a class of magnetic resonance (MR) pulse sequences we call large-tip-angle (LTA) spin-echo (SE) imaging. In comparison to traditional SE sequences (denoted 90 degrees-180 degrees-echo), the LTA sequence is of the for...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199310000-00017
更新日期:1993-10-01 00:00:00
abstract::Magnetic resonance (MR) methods have been used to study the metabolic and vascular response of model tumors to tumor necrosis factor (TNF). Magnetic resonance measurements demonstrated acute reductions in tumor blood flow, measured from tumor uptake of D2O, and in tumor adenosine triphosphate (ATP), measured by 31P ma...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198912000-00022
更新日期:1989-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The author analyzes findings of consistency of rotator-cuff calcifications found at ultrasound (US)-guided needle treatment compared with findings of plain radiography, US, and computed tomography (CT). METHODS:Twenty patients had rotator-cuff calcifications (mean diameter, 1.5 cm; range, 1.1-...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199605000-00010
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000642
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000170447.45577.5e
更新日期:2005-08-01 00:00:00
abstract::The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197901000-00014
更新日期:1979-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Iopromide is a new monomeric, nonionic contrast agent that exhibits low osmolality and low viscosity in high concentration in aqueous solutions. Double-blind, randomized clinical trials have established the efficacy, safety, and tolerance of iopromide for excretory urography, coronary angiograp...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-199405001-00015
更新日期:1994-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200110000-00005
更新日期:2001-10-01 00:00:00
abstract::Left ventricular volume has been measured with ultrafast computed tomography. However, the accuracy with which this can be done is unknown. We therefore imaged with ultrafast computed tomography 11 rectangular phantoms, 20 to 225 ml, and 17 left ventricular casts, 15 to 112 ml. Two observers planimetered serial tomogr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199101000-00006
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to evaluate the use of dielectric pads for improving high spatial resolution imaging of the inner ear at 7 T. MATERIALS AND METHODS:Two sets of dielectric pads were designed using electromagnetic simulations and implemented using a deuterated suspension of barium titanate. Th...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000026
更新日期:2014-05-01 00:00:00
abstract:UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-200103000-00005
更新日期:2001-03-01 00:00:00
abstract::Maximum likelihood estimation, assuming a binormal model, has been used extensively to estimate the area under receiver operating characteristic (ROC) curves and thus provide an index of diagnostic accuracy for the comparison of two imaging systems. However, in some instances, a degenerate data set results in a fitted...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199007000-00016
更新日期:1990-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000138091.96320.f8
更新日期:2004-10-01 00:00:00
abstract::Capacity-limited elimination of sodium iopanoate and a reproducible apparent transport maximum (Tm) were demonstrated in nonoperated dogs having an intact enterohepatic circulation and normal endogenous bile salt pool. Using a multiple infusion technique, estimation of apparent Tm of iopanoate in the liver was possibl...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197601000-00007
更新日期:1976-01-01 00:00:00
abstract::Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198311000-00012
更新日期:1983-11-01 00:00:00
abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00058
更新日期:1988-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study assesses the ability of a cardiac-gated phase-contrast magnetic resonance imaging (MRI) technique to measure renal blood flow (RBF) noninvasively in humans. METHODS:In nine normal volunteers, total RBF in the renal arteries and in the left renal vein was estimated by MRI and correla...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199206000-00012
更新日期:1992-06-01 00:00:00
abstract:PURPOSE:To determine whether liver metastases conspicuity is improved at 80 kVp when compared with weighted average (WA) simulated 120 kVp data using dual source dual energy CT. METHODS:A total of 11 patients with 44 hypo-vascular liver metastases underwent contrast enhanced Dual Energy CT (DECT). In all cases the sub...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181dfda78
更新日期:2010-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the effect of the transverse ligament on translation of the menisci. METHODS:Six cadaveric knees were examined by MR imaging inside a positioning device before and after transecting the transverse ligament. The knees were examined at various positions: extension, 30 degrees of flex...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199909000-00002
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To assess prospectively, in healthy subjects and in patients with dilated cardiomyopathy (DCM) and hypertrophic obstructive cardiomyopathy (HOCM), the 3-dimensional (3D) shape, size, and motion of the mitral annulus (MA) using computed tomography (CT). MATERIALS AND METHODS:Twenty patients with no cardiac ab...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181994a73
更新日期:2009-04-01 00:00:00