Normal renal blood flow measurement using phase-contrast cine magnetic resonance imaging.

Abstract:

RATIONALE AND OBJECTIVES:This study assesses the ability of a cardiac-gated phase-contrast magnetic resonance imaging (MRI) technique to measure renal blood flow (RBF) noninvasively in humans. METHODS:In nine normal volunteers, total RBF in the renal arteries and in the left renal vein was estimated by MRI and correlated with RBF determined by the clearance of para-aminohippuric acid (CPAH) and the hematocrit level. RESULTS:Correlation of RBF estimated from left renal vein flow, with RBF by CPAH-hematocrit, yielded r = .86 (P less than .003). Repeated measurement of RBF by MRI demonstrated a high degree of reproducibility, with coefficients of variation ranging from 4.8% to 8.9%. However, the MRI measurements of arterial flow did not significantly correlate with the standard measurements. CONCLUSIONS:Reproducible noninvasive measurement of normal RBF is possible with the phase-contrast MRI technique used to measure renal venous blood flow.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Sommer G,Noorbehesht B,Pelc N,Jamison R,Pinevich AJ,Newton L,Myers B

doi

10.1097/00004424-199206000-00012

keywords:

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

465-70

issue

6

eissn

0020-9996

issn

1536-0210

journal_volume

27

pub_type

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