Contrast-to-noise-ratio measurements in three-dimensional magnetic resonance angiography.

Abstract:

RATIONALE AND OBJECTIVES:The authors report on the development and preliminary validation of a technique for measuring contrast-to-noise ratio (CNR) at all points along selected vessel segments in the original three-dimensional magnetic resonance angiography (MRA) dataset. METHODS:Contrast-to-noise ratio dependencies on flow rate, field of view, and flip angle were measured on images from a conventional time-of-flight MRA pulse sequence using constant flow in a branching vascular phantom. An estimate of the inherent variability of the technique was obtained from multiple scans of a flow phantom and a human volunteer. RESULTS:The overall standard deviation (SD) of the CNR was found to be approximately 6.1% of the average CNR value for the flow phantom study and 7.3% for the human study. Vessel CNR was found to increase with field of view and was found to become nonuniform for low flow rate and/or high flip angles. CONCLUSION:In general, such CNR measurements allow the investigation of the mechanism of signal loss and general technique optimization in MRA.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Du Y,Parker DL,Davis WL,Blatter DD

doi

10.1097/00004424-199311000-00005

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

1004-9

issue

11

eissn

0020-9996

issn

1536-0210

journal_volume

28

pub_type

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