Abstract:
PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a multicontrast high-resolution noninvasive vessel wall imaging approach at 3.0 T in patients with spontaneous CAD. METHODS AND MATERIALS:Ten patients with CAD of the internal carotid artery (ICA) were included in the study. 3.0 T MRI (Gyroscan Intera, Philips) was acquired using a dedicated phased-array coil. MRI-protocol consisted of: (1) bright blood 3D inflow MRA (TR/TE/FA = 25 milliseconds/3.1 millisecond/16 degrees , 120 slices, reconstructed voxel size 0.3 x 0.3 x 0.8 mm); (2) black blood cardiac-gated water-selective T1w 3D spoiled GE (TR/TE/FA = 31 milliseconds/7.7 milliseconds/15 degrees , 36 slices, 0.3 x 0.3 x 1.0 mm); and (3) black blood cardiac triggered fat suppressed T2w TSE (TR/TE/ETL = 3 heart beats/44 milliseconds/7, 18 slices, 0.3 x 0.3 x 2 mm). Three observers in consensus performed image analysis. Special attention was paid to the integrity of the luminal and adventitial vessel boundary and the presence of a communicating intimal tear or flap. RESULTS:3.0 T MRI provided excellent delineation of vessel lumen and vessel wall as a result of the nearly complete suppression of arterial blood signal. An intramural hematoma could be identified in all patients, confined between the luminal and adventitial vessel boundary. In no patient a communicating intimal tear could be identified. Clear distinction between intramural hematoma and thrombus was possible. CONCLUSION:High-resolution vessel wall imaging in patients with acute CAD is feasible. The increased signal-to-noise ratio at 3.0 T can be invested to obtain a higher spatial resolution, permitting depiction of intimal and adventitial vessel wall boundary and the intramural hematoma in the diseased vessel segment. The morphologic information that is gained is helpful in the understanding of the underlying pathomechanismen of CAD.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Bachmann R,Nassenstein I,Kooijman H,Dittrich R,Kugel H,Niederstadt T,Kuhlenbäumer G,Ringelstein EB,Krämer S,Heindel Wdoi
10.1097/01.rli.0000195836.57778.1fkeywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
105-11issue
2eissn
0020-9996issn
1536-0210pii
00004424-200602000-00007journal_volume
41pub_type
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journal_title:Investigative radiology
pub_type: 杂志文章
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journal_title:Investigative radiology
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journal_title:Investigative radiology
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journal_title:Investigative radiology
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