Abstract:
:Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-concentration curve may be degraded. To the extent that contrast medium tonicity reduces curve peak or increases width, image quality for mask mode IV-DSA will suffer. To quantify the effect of contrast medium tonicity upon curve shape, contrast medium (1) at increasing iodine concentration and increasing osmolality and (2) at constant iodine concentration and increasing osmolality was injected into the right atria of mongrel dogs. In both experiments, increasing osmolality was associated with an increase in central blood volume (CBV) and cardiac output. With an increase in CBV, curve peak fell. With an increase in both CBV and cardiac output, curve width was not influenced by increasing osmolality. The effect of osmolality upon CBV was highly variable; in these experiments CBV was influenced more by subject-to-subject variability. However, on the average, higher tonicity contrast media produced curves with lower peaks. These studies suggest that isotonic contrast medium does not increase CBV and that isotonic contrast medium is preferable to hypertonic contrast medium for IV-DSA image formation.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Burbank FH,Thompson WMdoi
10.1097/00004424-198603000-00009subject
Has Abstractpub_date
1986-03-01 00:00:00pages
240-7issue
3eissn
0020-9996issn
1536-0210journal_volume
21pub_type
杂志文章abstract::Sixteen observers averaging 7.4 years experience in interpreting radiology images and 16 observers without radiology training were tested for their ability to detect low-contrast signals in structured noise backgrounds using a digital display system. No significant difference in true positives, false positives, time t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198704000-00006
更新日期:1987-04-01 00:00:00
abstract::An isotopic radiation source 125I was investigated for use in soft tissue radiaography, with particular attention to possible use in mammography for mass screening. Film sensitivities, exposure rates, absorbed doeses, contrast and resolution were determined, and compared to conventional x-ray units. It was found that ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197509000-00007
更新日期:1975-09-01 00:00:00
abstract:OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31822311a9
更新日期:2011-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:The purpose of this study was to investigate the feasibility, efficacy, and safety of ultrasound-guided percutaneous cryotherapy of stage T1 breast cancers. MATERIALS AND METHODS:Thirty patients with biopsy-confirmed breast cancers with tumor diameters of 15 mm or smaller (range, 5-15 mm; media...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000166935.56971.ff
更新日期:2005-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Emulsions of perfluorocarbons (PFCs) have been tested as blood substitutes. However, evidence exists that there is long-term retention of some PFCs by the organs of the reticuloendothelial system (RES). The authors investigate organ retention of the blood substitute component, perfluorotripropy...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199208000-00012
更新日期:1992-08-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b66d11
更新日期:2009-12-01 00:00:00
abstract::A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198307000-00009
更新日期:1983-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 9...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199404000-00010
更新日期:1994-04-01 00:00:00
abstract::A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198011001-00065
更新日期:1980-11-01 00:00:00
abstract:OBJECTIVES:The purposes of this study were to evaluate the reference range of quantitative computed tomography (QCT) measures of lung attenuation and airway parameter measurements in healthy nonsmoking adults and to identify sources of variation in those measures and possible means to adjust for them. MATERIALS AND ME...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318262292e
更新日期:2012-10-01 00:00:00
abstract::Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and di...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198910000-00010
更新日期:1989-10-01 00:00:00
abstract::The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197901000-00014
更新日期:1979-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199604000-00005
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:There is little published information regarding the efficacy of paclitaxel-coated balloon catheters except for the iopromide-containing formulation, and less is known about the kind of toxicity at overdose. The aim of our study was to assess 2 different paclitaxel matrix formulations on angioplasty balloon ca...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31820577df
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To determine whether time-resolved magnetic resonance angiography (TR-MRA) with ultra-low-dose gadolinium chelate (1.5-3.0 mL) can reliably detect or rule out hemodynamically significant disease in the carotid-vertebral artery territory. MATERIALS AND METHODS:Hundred consecutive patients (62 women, 38 men, mea...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31819ca048
更新日期:2009-04-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199212002-00014
更新日期:1992-12-01 00:00:00
abstract:PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000195836.57778.1f
更新日期:2006-02-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199709000-00004
更新日期:1997-09-01 00:00:00
abstract::Effectiveness of terbutaline, a potent uterine muscle relaxant, for differentiation of temporary and anatomic interstitial fallopian tube obstruction (IFTO) at hysterosalpingography (HSG) was explored. In 43 IFTO evaluated, HSG after terbutaline showed patency in only one of 16 tubes in which IFTO was caused by spasm ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198803000-00010
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:To determine the reproducibility, accuracy, and predictors of accuracy of computed tomography (CT) angiography to detect and characterize coronary atherosclerotic plaque as compared with intravascular ultrasound. METHODS:Ten ex vivo human coronary arteries were imaged in a moving phantom by dual-source CT (col...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181e0a541
更新日期:2010-11-01 00:00:00
abstract::Simultaneous inflation of two balloons may be necessary for balloon dilation valvuloplasty in patients with a large annulus. We examined the cardiovascular effects of dilating the pulmonary annulus with two balloons in 18 normal dogs using pulsed Doppler ultrasound and gross and microscopic examination. When the ratio...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198808000-00005
更新日期:1988-08-01 00:00:00
abstract::A method of teaching radiology residents by identification of general and specific objectives to be accomplished during each time segment of the four-year training program has been developed. The objectives are incorporated into an educational contract that is signed by the resident and rotation director at the beginn...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198612000-00009
更新日期:1986-12-01 00:00:00
abstract::Altered concentrations of brain beta endorphin and spinal cord encephalin have been reported in mice with iatrogenic arachnoiditis. We measured beta-endorphin concentration in cerebrospinal fluid (CSF) in normal monkeys and in monkeys with various degrees of arachnoiditis resulting from myelography and spinal surgery ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198803000-00006
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:Dynamic ventilation (3)He-MRI is a new method to assess pulmonary gas inflow. As differing airway diameters throughout the ventilatory cycle can influence gas inflow this study intends to investigate the influence of volume and timing of a He gas bolus with respect to the beginning of the tidal volume on insp...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181690111
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the impact of impaired renal function on gadolinium (Gd) retention in various organs after Gd-based contrast agent injection. MATERIALS AND METHODS:After local animal care and review committee approval, 23 normal mice and 26 with renal failure were divided into 4 tre...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000295
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000138091.96320.f8
更新日期:2004-10-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199804000-00008
更新日期:1998-04-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199402000-00007
更新日期:1994-02-01 00:00:00
abstract::Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198209000-00009
更新日期:1982-09-01 00:00:00
abstract::A new nonionic contrast medium (CM), ioxilan, was compared with iohexol and iopamidol. Following incubation of whole heparinized blood with CM, the morphology and osmotic fragility of erythrocytes were studied, the former by transmission electron microscopy. Effects on platelets and hemocoagulation were determined by ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00032
更新日期:1988-09-01 00:00:00