Abstract:
RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 99mTc-HMPAO leukocytes in healthy subjects. METHODS:Five healthy volunteers had leukocytes labeled with 99mTc-HMPAO. After injection of the labeled leukocytes, whole body images and blood and urine samples were obtained at multiple time points. RESULTS:Visual interpretation of the images demonstrated significant bowel activity as early as 2 hours and increasing with time such that one the 8- and 24-hour images, the amount of bowel activity would preclude using 99mTc-HMPAO leukocyte scanning for abdominal processes. The dosimetry for this study is similar to that of other studies and is in an acceptable diagnostic range. CONCLUSIONS:99mTc-HMPAO leukocyte studies are an acceptable alternative to 111In-labeled leukocyte studies in terms of dosimetry. Use of such studies in the abdomen should be limited to early images, usually before 2 hours, to avoid confusion with the normal route of excretion in the bowel.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Brown ML,Hung JC,Vetter RJ,O'Connor MK,Chowdhury S,Forstrom LAdoi
10.1097/00004424-199404000-00010subject
Has Abstractpub_date
1994-04-01 00:00:00pages
443-7issue
4eissn
0020-9996issn
1536-0210journal_volume
29pub_type
杂志文章abstract:OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318181538a
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To compare image quality and geometric distortion between readout-segmented diffusion-weighted imaging (rs-DWI) and selective-excitation accelerated reduced-field of view (FOV) DWI (sTX-DWI) of the prostate. MATERIALS AND METHODS:Sixty-five patients underwent 3-T MRI of the prostate including rs-DWI and sTX-...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000184
更新日期:2015-11-01 00:00:00
abstract::A method of teaching radiology residents by identification of general and specific objectives to be accomplished during each time segment of the four-year training program has been developed. The objectives are incorporated into an educational contract that is signed by the resident and rotation director at the beginn...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198612000-00009
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the potential of quantitative assays of vascular characteristics based on dynamic contrast-enhanced magnetic resonance imaging (MRI) using a macromolecular contrast medium (MMCM) to search for and measure effects of dimethyl sulfoxide (DMSO) on cancer vasculature with microscopic correlations. M...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318164b71d
更新日期:2008-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200204000-00003
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:The aim of this pilot study was to assess post-treatment apparent diffusion coefficient (ADC) changes of diffuse large B-cell lymphoma lesions on respiratory-gated whole-body diffusion-weighted imaging (DWI), with integrated (18)F-fluoro-2-deoxyglucose positron emission tomography/computed tomography (PET/CT...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182087b03
更新日期:2011-05-01 00:00:00
abstract::With the ongoing development of new contrast agents, questions develop concerning the cardiac effects of these drugs. We used the perfused rat heart model to investigate the effects on cardiac and coronary function of hypertonic ionic (sodium chloride) and nonionic (glucose) solutions and conventional and low osmolali...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199003000-00009
更新日期:1990-03-01 00:00:00
abstract::Arterial occlusion by direct-current transcatheter electrocoagulation (TCEC) has been developed experimentally and used successfully in clinical situations. The major shortcoming of the technique has been the lengthy time necessary for occlusion of larger arteries. In the present study we attempted to decrease the tim...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198203000-00011
更新日期:1982-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA). METHODS:One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200207000-00005
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:The goal of this study was to demonstrate feasibility of measuring extracellular pH in cartilage and meniscus using acidoCEST technique with a 3-dimensional ultrashort echo time readout (acidoCEST-UTE) magnetic resonance imaging (MRI). MATERIALS AND METHODS:Magnetization transfer ratio asymmetry, radiofrequ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000576
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b66d11
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate image quality of a spectral photon-counting detector (PCD) computed tomography (CT) system for evaluation of major arteries of the head and neck compared with conventional single-energy CT scans using energy-integrating detectors (EIDs). METHODS:In this institutional r...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000418
更新日期:2018-03-01 00:00:00
abstract::Thromboembolic complications occurring during angiography may result from a number of different causes. Catheters and guidewires can interact with blood to form thrombi; this tendency is related to wall defects and the chemical composition and structural characteristics of the catheters and guidewires. Nonthrombic sou...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/00004424-198811002-00009
更新日期:1988-11-01 00:00:00
abstract::High-resolution real-time ultrasonography (5, 7.5, and 10 MHz) was used to examine the menisci of the knee in ten normal volunteers and in ten patients with knee injuries. The posterior horns of the medial and lateral menisci were easily demonstrated. Normal anatomy and pathologic changes could be imaged in the menisc...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198604000-00008
更新日期:1986-04-01 00:00:00
abstract:OBJECTIVES:Magnetic resonance imaging guidance has been sporadically reported for renal tumor cryoablation (CA); therefore, clinical experience with this modality is still limited.The aim of this study is to retrospectively analyze our 10-year experience with renal tumor CA performed on a 1.5 T magnetic resonance imagi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000719
更新日期:2020-09-04 00:00:00
abstract::Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198902000-00005
更新日期:1989-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The vascular opacification characteristics of a new nonionic, dimeric contrast agent, iodixanol, have been compared with a nonionic, monomeric agent, iohexol, using ultrafast computed tomography (UFCT). METHODS:In 10 experiments with mongrel dogs, the contrast agents were alternately injected ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199212000-00011
更新日期:1992-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate different vein graft-coated stent systems in the endovascular treatment of experimental arteriovenous fistulae (AVF) in a canine model. METHODS:Bilateral carotid-to-external jugular vein AVF were created. Two balloon-expandable tantalum stents (Strecker stent), two self-expanding n...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199901000-00004
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199306000-00011
更新日期:1993-06-01 00:00:00
abstract::Using simple surgical techniques, experimental carotid aneurysms are created which simulate some types of human berry aneurysms, both in hemodynamic and radiographic behavior. End to side anastomoses of an external jugular vein graft to the common carotid artery can be carried out by radiologic personnel with no forma...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197703000-00009
更新日期:1977-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199210000-00014
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess the effectiveness of a model-based iterative reconstruction (MBIR) in improving image quality and diagnostic performance of ultralow-dose computed tomography (ULDCT) of the lung. MATERIALS AND METHODS:The institutional review board approved this study, and all patients pr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182562a89
更新日期:2012-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199401000-00012
更新日期:1994-01-01 00:00:00
abstract::Trypan blue and 197HgCl2 were used as markers of the increased leakage through the blood-brain barrier which developed after selective injection of different contrast media formulations into the internal carotid arteries of rabbits. Interest was focused on a new, experimental, nonionic medium (C-29) and possible effec...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197907000-00007
更新日期:1979-07-01 00:00:00
abstract::The purpose of our investigation was to determine whether iopanoyl glucuronide, the major metabolite of iopanoic acid (Telepaque), undergoes hydrolysis by bacterial beta-glucuronidase in dogs. The conjugated compound was identified and quantitated by elemental analysis, fluorescent excitation analysis, thin-layer chro...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197805000-00011
更新日期:1978-05-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of an 80-kVp protocol using a moderate concentration contrast material (MC-CM) for cerebral computed tomography angiography by comparison with a conventional 120-kVp protocol using a high concentration contrast material (HC-CM). MATERIALS AND METHODS:Attenuation values and sign...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31823076a4
更新日期:2012-02-01 00:00:00
abstract::Using real-time ultrasound, the motions of the tongue, hyoid bone, and larynx were monitored and timed during swallowing in ten normal subjects. A well-defined propulsive wave of the tongue was observed during swallowing a 5-cc water bolus. The body of the hyoid bone was identified on the ultrasound scan as a high ech...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198403000-00003
更新日期:1984-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199711000-00010
更新日期:1997-11-01 00:00:00
abstract::Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac oste...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197511000-00008
更新日期:1975-11-01 00:00:00
abstract::Because of a need to correlate pulmonary microvascular changes with physiologic data during lung injury, in vitro and in vivo pulmonary capillary microangiography was performed on normal dogs and those subjected to oleic acid injury and glass bead microembolization. During these studies, no significant differences wer...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00