The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation, and vascularization.

abstract：OBJECTIVES:X-ray computed tomography (CT) using phase contrast can provide images with greatly enhanced soft-tissue contrast in comparison to conventional attenuation-based CT. We report on the first scan of a human specimen recorded with a phase-contrast CT system based on an x-ray grating interferometer and a convent...

journal_title：Investigative radiology

authors： Donath T,Pfeiffer F,Bunk O,Grünzweig C,Hempel E,Popescu S,Vock P,David C

更新日期：2010-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...

journal_title：Investigative radiology

authors： Lawaczeck R,Diekmann F,Diekmann S,Hamm B,Bick U,Press WR,Schirmer H,Schön K,Weinmann HJ

更新日期：2003-09-01 00:00:00

abstract：:Magnetic resonance angiography (MRA) for application in the musculoskeletal system is progressing at a rapid pace. The clinical role of this new technique is still being developed, although a number of uses have already become well recognized, and MRA is diffusing into clinical practice. This article describes the bas...

journal_title：Investigative radiology

authors： Harms SE,Flamig DP

更新日期：1992-12-01 00:00:00

abstract：:We measured the amounts of three types of radiographic contrast media (RCM) that could be entrapped in liposomes prepared by the dehydration-rehydration vesicle (DRV) technique. To make DRVs, one initially makes water-containing, small unilamellar vesicles, adds contrast media and lyophilizes the mixture. Upon rehydra...

journal_title：Investigative radiology

authors： Seltzer SE,Gregoriadis G,Dick R

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...

journal_title：Investigative radiology

authors： Maroules CD,McColl R,Khera A,Peshock RM

更新日期：2008-09-01 00:00:00

abstract：:Receiver operating characteristic (ROC) analysis has been used in a broad variety of medical imaging studies during the past 15 years, and its advantages over more traditional measures of diagnostic performance are now clearly established. But despite the essential simplicity of the approach, workers in the field ofte...

journal_title：Investigative radiology

authors： Metz CE

更新日期：1989-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors developed a two-dimensional breathhold magnetic resonance (MR) technique for the direct imaging of pulmonary emboli. METHODS:In vitro MR imaging was performed to demonstrate the potential generation of clot-blood contrast by in vivo pulmonary embolism (PE). A two-dimensional magnet...

journal_title：Investigative radiology

authors： Moody AR,Liddicoat A,Krarup K

更新日期：1997-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：:Percutaneous injection of absolute ethanol into adenocarcinomas implanted in the hind leg of rats was evaluated as a potential cancer treatment. Intramuscular alcohol injections up to 10 mL/kg produced a local dose-dependent coagulation necrosis followed by granulation tissue formation and subsequent fibrosis but no a...

journal_title：Investigative radiology

authors： Burgener FA,Steinmetz SD

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific dif...

journal_title：Investigative radiology

authors： Maas MC,Litjens GJS,Wright AJ,Attenberger UI,Haider MA,Helbich TH,Kiefer B,Macura KJ,Margolis DJA,Padhani AR,Selnæs KM,Villeirs GM,Fütterer JJ,Scheenen TWJ

更新日期：2019-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The suitability of paramagnetic complexes as magnetic resonance contrast agents depends on various factors such as their relaxivity, stability, selectivity, and the inertness toward transmetallation by endogenous ions. The transmetallation of a series of 18 gadolinium complexes by the Zn2+ ion ...

journal_title：Investigative radiology

authors： Laurent S,Elst LV,Copoix F,Muller RN

更新日期：2001-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Diabetic patients frequently suffer contrast media-induced nephropathy. Hyperglycemia in diabetes mellitus causes gradual deterioration of glomerular mesangial cells (MCs) in the kidney. In this study, the authors investigated the response of rat MCs cultured in high-glucose medium to diatrizoa...

journal_title：Investigative radiology

authors： Wasaki M,Sugimoto J,Shirota K

更新日期：2001-07-01 00:00:00

abstract：:Using a 1.5 T magnetic resonance imaging (MRI) system, cine phase-contrast and magnitude images were obtained in three phantoms that simulated different anatomic configurations of aortic dissection. The dissection phantoms were made of compliant materials, and pulsatile flow was used in all experiments. Phantoms diffe...

journal_title：Investigative radiology

authors： Iwai F,Sostman HD,Evans AJ,Nadel SN,Hedlund LW,Beam CA,Charles HC,Spritzer CE

更新日期：1991-12-01 00:00:00

abstract：:The residency program at the University of Pennsylvania offers a 1-month fellowship for senior residents in medical student education. Instructional philosophy, methods, and content are discussed, observed, practiced, and evaluated. Close supervision and immediate feedback provide training particularly needed by futur...

journal_title：Investigative radiology

authors： Troupin RH

更新日期：1990-06-01 00:00:00

abstract：:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

journal_title：Investigative radiology

authors： Gould RG

更新日期：1992-12-01 00:00:00

abstract：:The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...

journal_title：Investigative radiology

authors： Mironidou M,Ximitidou O,Christopoulos S,Kokkas B

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...

journal_title：Investigative radiology

authors： Radbruch A,Weberling LD,Kieslich PJ,Hepp J,Kickingereder P,Wick W,Schlemmer HP,Bendszus M

更新日期：2015-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study was to determine whether cerebral fat embolism demonstrated reversible or irreversible findings in magnetic resonance (MR) imaging over time and to compare the features in MR images with histologic findings in a cat model. MATERIALS AND METHODS:MR images were obtained...

journal_title：Investigative radiology

authors： Kim HJ,Lee CH,Lee SH,Moon TY

更新日期：2003-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Ultrasound can cause destruction of microbubble contrast agents used to enhance medical ultrasound imaging. This study sought to characterize the dynamics of this interaction by direct visual observation of microbubbles during insonification in vitro by a medical ultrasound imaging system. MET...

journal_title：Investigative radiology

authors： Klibanov AL,Ferrara KW,Hughes MS,Wible JH Jr,Wojdyla JK,Dayton PA,Morgan KE,Brandenburger GH

更新日期：1998-12-01 00:00:00

abstract：:Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...

journal_title：Investigative radiology

authors： Kaliner M,Dyer J,Merlin S,Shelton A,Greenhill A,Treadwell G,McKenna W,Lieberman P

更新日期：1984-03-01 00:00:00

abstract：:Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and di...

journal_title：Investigative radiology

authors： Feuerstein IM,Girton ME

更新日期：1989-10-01 00:00:00

abstract：:The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...

journal_title：Investigative radiology

authors： Ferrante SL,Schreiman JS,Rouse JW,Rysavy JA,Cheng SC,Frick MP

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00

abstract：:Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...

journal_title：Investigative radiology

authors： Griffith SL,Burney BT,Fry FJ,Franklin TD Jr

更新日期：1989-02-01 00:00:00

abstract：:A silicone gel phantom material is described. It can be molded into any shape and it can contain internal cavities. The material is selfsealing allowing the cavities to be filled with liquids. A simple geometric phantom consisting of a rectangular solid with a single internal spherical cavity was fabricated and imaged...

journal_title：Investigative radiology

authors： Goldstein DC,Kundel HL,Daube-Witherspoon ME,Thibault LE,Goldstein EJ

更新日期：1987-02-01 00:00:00

abstract：:Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...

journal_title：Investigative radiology

authors： Berk RN,Barnhart JL,Nazareno G,Witt BL

更新日期：1981-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

journal_title：Investigative radiology

authors： Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

更新日期：1995-08-01 00:00:00

abstract：:We developed a new, cineangiographic method to accurately measure the dynamic changes in the internal diameter of human arteries in vivo. Cine films were digitized at a spatial resolution of 4 microns/pixel, using a line image sensor. The vessel edges, with a Gaussian fit to a unilateral profile curve of the vessel, w...

journal_title：Investigative radiology

authors： Sugahara T,Yanagihara Y,Uyama C,Maeda H,Takafuchi M,Azumi T

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVES:Contrast-enhanced ultrasound imaging is increasingly being used in the clinic for assessment of tissue vascularity. The purpose of our study was to evaluate the effect of different contrast administration parameters on the in vivo ultrasound imaging signal in tumor-bearing mice using a maximum intensity pers...

journal_title：Investigative radiology

authors： Pysz MA,Foygel K,Panje CM,Needles A,Tian L,Willmann JK

更新日期：2011-03-01 00:00:00

abstract：:Magnetic resonance (MR) methods have been used to study the metabolic and vascular response of model tumors to tumor necrosis factor (TNF). Magnetic resonance measurements demonstrated acute reductions in tumor blood flow, measured from tumor uptake of D2O, and in tumor adenosine triphosphate (ATP), measured by 31P ma...

journal_title：Investigative radiology

authors： Karczmar GS,Meyerhoff DJ,Speder A,Valone F,Wilkinson M,Shine N,Boska MD,Weiner MW

更新日期：1989-12-01 00:00:00