The effect of radiographic contrast media on leukocyte motility.

abstract：OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...

journal_title：Investigative radiology

authors： Hahn G,Sorge I,Gruhn B,Glutig K,Hirsch W,Bhargava R,Furtner J,Born M,Schröder C,Ahlström H,Kaiser S,Moritz JD,Kunze CW,Shroff M,Stokland E,Trnkova ZJ,Schultze-Mosgau M,Reif S,Bacher-Stier C,Mentzel HJ

更新日期：2009-12-01 00:00:00

abstract：:Virtually all receiver operating characteristic (ROC) studies of medical imaging methods have involved data collected on a discrete confidence-rating scale, though in principle ROC studies can be conducted with either discrete or continuous scales. Continuous scales provide potential advantages in medical applications...

journal_title：Investigative radiology

authors： Rockette HE,Gur D,Metz CE

更新日期：1992-02-01 00:00:00

abstract：:We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...

journal_title：Investigative radiology

authors： Hayakawa K,Yamashita K

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

journal_title：Investigative radiology

authors： Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

更新日期：2015-05-01 00:00:00

abstract：:A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...

journal_title：Investigative radiology

authors： Sorenson JA,Niklason LT,Nelson JA

更新日期：1981-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors determine the value of contrast-enhanced, three-dimensional (3D) magnetic resonance angiography (MRA) in the assessment of the renal arteries in comparison with conventional arteriography (CA). METHODS:One hundred three patients (71 m, 32 f) were evaluated with both CA and 3D MRA. ...

journal_title：Investigative radiology

authors： Hany TF,Leung DA,Pfammatter T,Debatin JF

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop a method to determine hepatic and renal clearance of the 2 diastereoisomers (Gd-A, Gd-B) of Gd-EOB-DTPA separately. MATERIALS AND METHODS:Between July 2017 and February 2018, 41 patients with hepatic disease were prospectively included. For each patient, 1 mL of iopromid...

journal_title：Investigative radiology

authors： Yuan X,Wang S,Shi W,Cai Y,Chen Y,Chen M,Peng Y,Ao G

更新日期：2020-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Echogenic antibody-conjugated anionic liposomes have been developed that allow directed tissue targeting and acoustic enhancement. These are not efficient for gene delivery. A cationic formulation that allows directed gene delivery while retaining acoustic properties may provide more efficient ...

journal_title：Investigative radiology

authors： Tiukinhoy SD,Mahowald ME,Shively VP,Nagaraj A,Kane BJ,Klegerman ME,MacDonald RC,McPherson DD,Matsumura JS

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the ability of a flow-sensitive alternating inversion recovery-arterial spin labeling (FAIR-ASL) technique to track renal perfusion changes during pharmacologic and physiologic alterations in renal blood flow using microspheres as a gold standard. MATERIALS AND METHODS...

journal_title：Investigative radiology

authors： Artz NS,Wentland AL,Sadowski EA,Djamali A,Grist TM,Seo S,Fain SB

更新日期：2011-02-01 00:00:00

abstract：:The interdisciplinary approach to medical education has often been deficient in medical school curricula. Because of the nonintegrated approach to medical education, problem solving capabilities are not fostered. The clinical presentation of a patient, the imaging modalities used to investigate the patient, and the ul...

journal_title：Investigative radiology

authors： Oldham SA,Jacobson F

更新日期：1986-04-01 00:00:00

abstract：:We investigated the feasibility of using intravascular ultrasound imaging to analyze vascular physiology in various arterial beds. Canine superficial femoral, external iliac, and common carotid arteries were harvested and suspended and perfused in a bath of oxygenated, heated, physiologic salt solution. A 6-Fr, 20-MHz...

journal_title：Investigative radiology

authors： Wilson MW,Webb RC,Marx MV,Meyer CR,Gallagher MA,Haarer SL,Buda AJ,Williams DM

更新日期：1991-03-01 00:00:00

abstract：:The extent to which various concentrations of the paramagnetic metal ions [gadolinium (III), manganese (II), chromium (III), iron (III), nickel (II), copper (II), and cobalt (II)] affect proton magnetic relaxation times of distilled water, 4% human serum albumin (HSA), and dog plasma was studied in vitro. The pH of wa...

journal_title：Investigative radiology

authors： Barnhart JL,Berk RN

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:Computed tomography (CT) and magnetic resonance imaging (MRI) are introduced as an alternative to traditional autopsy. The purpose of this study was to investigate their accuracy in mass estimation of liver and spleen. METHODS:In 44 cases, the weights of spleen and liver were estimated based on MRI and CT da...

journal_title：Investigative radiology

authors： Jackowski C,Thali MJ,Buck U,Aghayev E,Sonnenschein M,Yen K,Dirnhofer R,Vock P

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...

journal_title：Investigative radiology

authors： Quattrocchi CC,Errante Y,Mallio CA,Marinelli L,LoVullo G,Giannotti G,Della Sala SW,van der Molen AJ,Beomonte Zobel B

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of combining inner-volume imaging (IVI) techniques with conventional multishot periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) techniques for targeted-PROPELLER magnetic resonance imaging. MATERIALS AND METHODS:Perpendicular section-selective ...

journal_title：Investigative radiology

authors： Deng J,Larson AC

更新日期：2009-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The suitability of paramagnetic complexes as magnetic resonance contrast agents depends on various factors such as their relaxivity, stability, selectivity, and the inertness toward transmetallation by endogenous ions. The transmetallation of a series of 18 gadolinium complexes by the Zn2+ ion ...

journal_title：Investigative radiology

authors： Laurent S,Elst LV,Copoix F,Muller RN

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the diagnostic value and safety of the contrast agent gadoterate meglumine (Gd-DOTA, DOTAREM, Guerbet, Roissy CdG Cedex, France) in the setting of a postmarketing surveillance study. MATERIALS AND METHODS:Between January 2004 and October 2005, radiologists in 61 radiol...

journal_title：Investigative radiology

authors： Herborn CU,Honold E,Wolf M,Kemper J,Kinner S,Adam G,Barkhausen J

更新日期：2007-01-01 00:00:00

abstract：:The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...

journal_title：Investigative radiology

authors： Ferrante SL,Schreiman JS,Rouse JW,Rysavy JA,Cheng SC,Frick MP

更新日期：1990-02-01 00:00:00

abstract：:The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...

journal_title：Investigative radiology

authors： Mironidou M,Ximitidou O,Christopoulos S,Kokkas B

更新日期：1998-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The efficacy of gadoteridol for contrast enhancement of central nervous system pathology was assessed in a multicenter clinical trial involving 411 patients suspected of having intracranial or spinal pathology. METHODS:Magnetic resonance imaging was performed before and after intravenous admin...

journal_title：Investigative radiology

authors： Runge VM,Bronen RA,Davis KR

更新日期：1992-08-01 00:00:00

abstract：:The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

journal_title：Investigative radiology

authors： Roberts JG,DiTomasso E,Webber CE

更新日期：1982-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:High signal intensity in the basal ganglia on T1-weighted MR imaging has been reported in chronic manganese (Mn) poisoning. However, the exact meaning of the high signal intensity remains unclear: does it result from Mn itself, secondary pathologic changes of the brain tissue, or both? The goal...

journal_title：Investigative radiology

authors： Kim SH,Chang KH,Chi JG,Cheong HK,Kim JY,Kim YM,Han MH

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the magnetic resonance prostate imaging reporting and data system (PI-RADS) for the detection of prostate cancer by the results of magnetic resonance imaging (MRI)-guided biopsy of the prostate as a reference standard. PATIENTS AND METHODS:In 55 patients who had underg...

journal_title：Investigative radiology

authors： Baur AD,Maxeiner A,Franiel T,Kilic E,Huppertz A,Schwenke C,Hamm B,Durmus T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Gadolinium leakage in ocular structures (GLOS) was recently observed in fluid-attenuated inversion recovery (FLAIR) images obtained the day after an initial gadolinium injection in stroke patients. The specificity of GLOS to stroke and its mechanisms remain unclear. OBJECTIVE:We investigated the factors ass...

journal_title：Investigative radiology

authors： Galmiche C,Moal B,Marnat G,Sagnier S,Schweitzer C,Dousset V,Sibon I,Tourdias T

更新日期：2021-01-19 00:00:00

abstract：:Radiolabeled blood cells are widely used for both clinical and research studies. In vitro and in vivo studies have shown the tagging process does not significantly affect function. The labeling techniques and clinical uses of labeled leukocytes and platelets are reviewed. ...

journal_title：Investigative radiology

authors： Datz FL

更新日期：1986-03-01 00:00:00

abstract：:A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

journal_title：Investigative radiology

authors： Sovak M,Siefert HM,Ranganathan R

更新日期：1980-11-01 00:00:00

abstract：:Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...

journal_title：Investigative radiology

authors： Schuhmann-Giampieri G,Schmitt-Willich H,Frenzel T,Press WR,Weinmann HJ

更新日期：1991-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

journal_title：Investigative radiology

authors： Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

更新日期：1995-08-01 00:00:00

abstract：:Screening chronic hemodialysis patients (CHD) for acquired cystic disease of the kidneys (ACDK) and its complications (hemorrhage and neoplasm) has become accepted management. We evaluated patients on CHD as well as patients on chronic peritoneal dialysis (CPD) for ACDK. The kidneys of 80 chronic dialysis patients wer...

journal_title：Investigative radiology

authors： Jabour BA,Ralls PW,Tang WW,Boswell WD Jr,Colletti PM,Feinstein EI,Massry SG

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

journal_title：Investigative radiology

authors： Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

更新日期：2010-04-01 00:00:00