Abstract:
OBJECTIVES:Magnetic resonance imaging guidance has been sporadically reported for renal tumor cryoablation (CA); therefore, clinical experience with this modality is still limited.The aim of this study is to retrospectively analyze our 10-year experience with renal tumor CA performed on a 1.5 T magnetic resonance imaging unit with the intent of reporting procedural safety and oncologic outcomes. MATERIALS AND METHODS:We included 143 patients (102 men; 41 women; median age, 73 years; range, 34-91 years) with 149 tumors (median size, 2.6 cm; range, 0.6-6.0 cm), treated between 2009 and 2019. Patient, tumor, procedure, and follow-up data were collected and analyzed. The Kaplan-Meier method was used to estimate local recurrence-free (LRFS), metastasis-free (MFS), disease-free (DFS), cancer-specific, and overall (OS) survival. Univariate and multivariate models were used to identify factors associated with complications, LRFS, MFS, DFS, and OS. RESULTS:The overall complication rate was 10.7% (16/149 tumors), with 1 major (1/149 [0.7%]; 95% confidence interval, 0.0%-3.7%) hemorrhagic complication. Other minor complications (15/149 [10.1%]; 95% confidence interval, 0.6%-16.1%) did not include any cases of injury to nearby organs. There were no factors associated with complications.Five-year estimates of LRFS (primary/secondary), MFS, DFS, cancer-specific survival, and OS were 82.8%/91.5%, 91.1%, 75.1%, 98.2%, and 89.6%, respectively. Increasing tumor size (hazard radio [HR], 1.8; P = 0.02) and intraparenchymal tumor location (HR, 5.6; P < 0.01) were associated with lower LRFS; increasing patient's age (HR, 0.5; P = 0.01), high tumor grade (HR, 23.3; P < 0.01) and non-clear-cell/nonpapillary histology (HR, 20.1; P < 0.01) with metastatic disease; and high tumor grade (HR, 3.2; P = 0.04) with lower DFS. CONCLUSION:Magnetic resonance imaging-guided CA of renal tumors is associated with acceptable morbidity and high survival estimates at 5-year follow-up. Given the absence of complications resulting from injuries to nearby organs, further studies are required to evaluate whether the potential reduced incidence of these adverse events justifies large-scale implementation of this interventional modality.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Cazzato RL,De Marini P,Leonard-Lorant I,Leclerc L,Auloge P,Tricard T,Dalili D,Garnon J,Lang H,Gangi Adoi
10.1097/RLI.0000000000000719subject
Has Abstractpub_date
2020-09-04 00:00:00eissn
0020-9996issn
1536-0210pub_type
杂志文章abstract::Low-dose transaxial tomography is a technique that can produce cross-sectional images of the hips and femurs in children to permit calculation of the angle of femoral anteversion. Transaxial tomography was compared with computed tomography in terms of measured radiation dose and image quality. Transaxial tomography wa...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::At a given radiation dosage and field of view, five variables are under meaningful control for intravenous digital subtraction angiography (IV-DSA): concentration and quantity of contrast media injected, volume of injectate, rate of injection, and site of injection. Some controversy exists regarding the selection of a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198401000-00007
更新日期:1984-01-01 00:00:00
abstract::The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198707000-00004
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS:Ten pat...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000381
更新日期:2017-10-01 00:00:00
abstract::We developed a new, cineangiographic method to accurately measure the dynamic changes in the internal diameter of human arteries in vivo. Cine films were digitized at a spatial resolution of 4 microns/pixel, using a line image sensor. The vessel edges, with a Gaussian fit to a unilateral profile curve of the vessel, w...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198909000-00005
更新日期:1989-09-01 00:00:00
abstract:UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-200103000-00005
更新日期:2001-03-01 00:00:00
abstract::The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199805000-00008
更新日期:1998-05-01 00:00:00
abstract::The authors investigated the effect on the brain of red blood cells that had been modified by contrast media. Rat blood was mixed with an equivolume of contrast media, and up to 200 microL of the mixture was infused to the internal carotid artery of the rat. Evans blue was administered intravenously to assess the inte...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198905000-00009
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate if pancreatic steatosis measured by proton density fat fraction (PDFF) is associated with exocrine pancreatic function defined by fecal elastase concentrations. MATERIALS AND METHODS:A total of 1458 volunteers (777 women; age range, 21-88 years) underwent magnetic re...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000554
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate accuracy of biliary anatomy depiction and quality of biliary tract visualization of magnetic resonance cholangiography (MRC) at 3.0 T in living potential liver donors (LPLDs). MATERIALS AND METHODS:Our institutional review board approved this study and did not require patient's inf...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31817e9b52
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...
journal_title:Investigative radiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/RLI.0000000000000058
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:Transcatheter arterial embolization (TAE) is used for the treatment of patients with malignant liver tumors. However, the proangiogenesis effect of TAE-associated hypoxia has not been adequately studied. The goal of this study was to determine angiogenic activity in tumors subjected to TAE by evaluating the ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000209663.00629.8a
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to assess whether the recently developed method of grating-based x-ray dark-field radiography can improve the diagnosis of pulmonary emphysema in vivo. MATERIALS AND METHODS:Pulmonary emphysema was induced in female C57BL/6N mice using endotracheal instillation of porcine pancr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000067
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS:Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000383
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to analyze the effect of dual-energy computed tomography (DECT) scanners and fluid characteristics on iodine quantification and to calculate the measurement variability range induced by those variables. METHODS:We performed an experimental phantom study with 4 mediastinal iodine ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000446
更新日期:2018-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199703000-00006
更新日期:1997-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The influence of lipiodol injection on hepatic morphology and function was investigated in 119 rabbits with hepatic VX2 tumors. METHODS:The rabbits were divided into the following three groups, according to the materials injected via the proper hepatic artery: group 1 received doxorubicin (Adr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199302000-00009
更新日期:1993-02-01 00:00:00
abstract::The Point Spread Function (PSF) in NMR imaging is the result of both the line broadening due to magnet field inhomogeneity and the intrinsic spectrum of the nucleus at resonance. In the case of proton imaging, the line broadening dominates the small chemical shifts and the spectral lines are not resolved. This is not ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198503000-00016
更新日期:1985-03-01 00:00:00
abstract::Frequency spectral analysis of cardiac wall motion as calculated from the recorded video kymogram are demonstrated. Characteristic harmonics following the fundamental frequency of the cardiac rate have been demonstrated to have an alternating sequential energy distribution as measured from the free margin of the left ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197503000-00005
更新日期:1975-03-01 00:00:00
abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00058
更新日期:1988-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the study was to determine optimal thresholds for semiquantitative perfusion parameters and to evaluate the influence of different segmentation models in detecting malperfused regions. MATERIAL AND METHODS:In 6 healthy subjects and 13 patients with coronary artery disease, contrast-...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000133816.83192.38
更新日期:2004-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria. METHODS:The device consists of a symmetrical cage of six superelastic monofile wires, including a mic...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199702000-00003
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVES:Imaging of the kidney using blood oxygen level dependent MR presents a major opportunity to examine differences in tissue oxygenation within the cortex and medulla applicable to human disease. We sought to define the differences between regions within kidneys and to optimize selection of regions of interest ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b4c1e8
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31827b711e
更新日期:2013-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199303000-00010
更新日期:1993-03-01 00:00:00
abstract::Virtually all receiver operating characteristic (ROC) studies of medical imaging methods have involved data collected on a discrete confidence-rating scale, though in principle ROC studies can be conducted with either discrete or continuous scales. Continuous scales provide potential advantages in medical applications...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199202000-00016
更新日期:1992-02-01 00:00:00
abstract::Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/00004424-199911000-00004
更新日期:1999-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Air microemboli may damage the cerebral microvasculature. The aim of this study was to evaluate the safety of ultrasound contrast agents composed of air microspheres with regard to cerebral damage when administered into the arterial system (ie, when not filtered by the capillary system of the l...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199803000-00001
更新日期:1998-03-01 00:00:00
abstract::The authors report a randomized, double-blind prospective trial comparing the effects of nonionic with ionic low-osmolar contrast media on erythrocyte aggregation. The study group comprised 40 consecutive patients with pathology necessitating selective angiography. Patients were examined using either ioxaglate 320, io...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-199108000-00009
更新日期:1991-08-01 00:00:00
abstract::Percutaneous injection of absolute ethanol into adenocarcinomas implanted in the hind leg of rats was evaluated as a potential cancer treatment. Intramuscular alcohol injections up to 10 mL/kg produced a local dose-dependent coagulation necrosis followed by granulation tissue formation and subsequent fibrosis but no a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198706000-00005
更新日期:1987-06-01 00:00:00