An experimental evaluation of central vs. peripheral injection for intravenous digital subtraction angiography (IV-DSA).

abstract：:The effects of an intravenously administered nitroxyl spin label (PCA) on the magnetic resonance imaging (MRI) appearance and relaxation times of acute canine myocardial infarctions were studied. Twenty-four hours after ligation of the left anterior descending coronary artery (LAD), animals were either sacrificed imme...

journal_title：Investigative radiology

authors： McNamara MT,Wesbey GE,Brasch RC,Sievers R,Lipton MJ,Higgins CB

更新日期：1985-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vasoconstriction of the renal arteries is frequently considered as a crucial factor for radiocontrast-induced nephropathy. A direct effect of iodinated radiographic contrast medium (RCM) on vascular smooth muscle is supposed to be one component of the vascular response. We studied the effec...

journal_title：Investigative radiology

authors： Uder M,Humke U,Pahl M,Jansen A,Utz J,Kramann B

更新日期：2002-08-01 00:00:00

abstract：:Over the past 120 years, continuous developments in medical imaging has improved diagnosis and treatment for many diseases and has thereby improved treatment outcome and quality of life of many patients. The number of computed tomography (CT) examinations is today increasing by 4% per year worldwide, for a total of ap...

journal_title：Investigative radiology

authors： Schöckel L,Jost G,Seidensticker P,Lengsfeld P,Palkowitsch P,Pietsch H

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To evaluate the dependency of tumor contrast enhancement (CE) in regard to protein-binding properties of contrast agents, using 4 different agents with a wide range of protein-binding capacities in a standardized rat brain glioma model. MATERIAL AND METHODS:Sixteen rats with implanted brain gliomas were evalua...

journal_title：Investigative radiology

authors： Wintersperger BJ,Runge VM,Tweedle MF,Jackson CB,Reiser MF

更新日期：2009-02-01 00:00:00

abstract：:Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrat...

journal_title：Investigative radiology

authors： Richards TL,Terrier F,Sievers RE,Lipton MJ,Moseley ME,Higgins CB

更新日期：1987-08-01 00:00:00

abstract：:Attenuation correction (AC) is an essential step in the positron emission tomography (PET) data reconstruction process to provide accurate and quantitative PET images. The introduction of PET/magnetic resonance (MR) hybrid systems has raised new challenges but also possibilities regarding PET AC. While in PET/computed...

journal_title：Investigative radiology

authors： Paulus DH,Quick HH

更新日期：2016-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Because of the complex relationships between the dynamic three-dimensional cardiac surface shape and its projected image, errors arise with the use of two-dimensional silhouettes to measure displacements of the heart. The character and frequency of such errors are examined. METHODS:A high-prec...

journal_title：Investigative radiology

authors： McInerney JJ,Weldner PW,Herr MD,Copenhaver GL

更新日期：1994-03-01 00:00:00

abstract：:Maximum likelihood estimation, assuming a binormal model, has been used extensively to estimate the area under receiver operating characteristic (ROC) curves and thus provide an index of diagnostic accuracy for the comparison of two imaging systems. However, in some instances, a degenerate data set results in a fitted...

journal_title：Investigative radiology

authors： Rockette HE,Obuchowski NA,Gur D

更新日期：1990-07-01 00:00:00

abstract：:Due to the nature of three-dimensional Fourier transform (3-DFT) data acquisition in magnetic resonance imaging (MRI), the spatial relation between a resolved volume element (a voxel) and the object can be manipulated easily. Those manipulations have practical consequences in terms of registering slice positions with ...

journal_title：Investigative radiology

authors： Kramer D,Li A,Simovsky I,Hawryszko C,Hale J,Kaufman L

更新日期：1990-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...

journal_title：Investigative radiology

authors： Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

更新日期：1999-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors differentiate acute tubular necrosis from transplant rejection in patients with delayed kidney graft function using gadolinium (Gd)-DTPA enhanced magnetic resonance (MR) imaging. METHODS:Twenty-four patients after renal transplantation (10 with normal graft function, 14 with delaye...

journal_title：Investigative radiology

authors： Preidler KW,Szolar D,Schreyer H,Ebner F,Kern R,Holzer H,Horina JH

更新日期：1996-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To present the results of two studies conducted to evaluate the pharmacokinetics and safety of iomeprol in healthy volunteers and in patients with various degrees of renal impairment. METHODS:In these two open-label, single-dose, phase I studies, a 50-mL dose of iomeprol 400 was administered i...

journal_title：Investigative radiology

authors： Lorusso V,Taroni P,Alvino S,Spinazzi A

更新日期：2001-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...

journal_title：Investigative radiology

authors： Speck U,Scheller B,Abramjuk C,Grossmann S,Mahnkopf D,Simon O

更新日期：2004-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Diabetic patients frequently suffer contrast media-induced nephropathy. Hyperglycemia in diabetes mellitus causes gradual deterioration of glomerular mesangial cells (MCs) in the kidney. In this study, the authors investigated the response of rat MCs cultured in high-glucose medium to diatrizoa...

journal_title：Investigative radiology

authors： Wasaki M,Sugimoto J,Shirota K

更新日期：2001-07-01 00:00:00

abstract：:The large intestines of eight boxer dogs with canine histiocytic ulcerative colitis (CHUC) and 10 normal dogs were studied by in vivo angiography and postmortem microangiography. The vascular abnormalities were correlated with the gross and histologic pathology found at necropsy. The angiographic abnormalities were ...

journal_title：Investigative radiology

authors： Lawson TL,Gomez JA,Margulis AR

更新日期：1975-05-01 00:00:00

abstract：:Early detection of pancreatic ductal adenocarcinoma (PDAC) represents the most significant step toward the treatment of this aggressive lethal disease. Previously, we engineered a preclinical Thy1-targeted microbubble (MBThy1) contrast agent that specifically recognizes Thy1 antigen overexpressed in the vasculature of...

journal_title：Investigative radiology

authors： Bam R,Daryaei I,Abou-Elkacem L,Vilches-Moure JG,Meuillet EJ,Lutz A,Marinelli ER,Unger EC,Gambhir SS,Paulmurugan R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Thermal dose in tumor tissue is a key factor for regional hyperthermia (HT) combined with chemotherapy and for drug delivery using thermosensitive liposomes (TSL). It influences therapy outcome, affects the accumulation of liposomes, and triggers the content release from TSL in the target tissue. For the dev...

journal_title：Investigative radiology

authors： Peller M,Schwerdt A,Hossann M,Reinl HM,Wang T,Sourbron S,Ogris M,Lindner LH

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:We compared the image quality and diagnostic performance of 2 fat-suppression methods for black-blood T2-weighted fast spin-echo (FSE), which are as follows: (a) short T1 inversion recovery (STIR; FSE-STIR) and (b) spectral adiabatic inversion recovery (SPAIR; FSE-SPAIR), for detection of acute myocardial in...

journal_title：Investigative radiology

authors： Srichai MB,Lim RP,Lath N,Babb J,Axel L,Kim D

更新日期：2013-01-01 00:00:00

abstract：:Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented. ...

journal_title：Investigative radiology

authors： Enge I

更新日期：1985-01-01 00:00:00

abstract：:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

journal_title：Investigative radiology

authors： Gould RG

更新日期：1992-12-01 00:00:00

abstract：:The Point Spread Function (PSF) in NMR imaging is the result of both the line broadening due to magnet field inhomogeneity and the intrinsic spectrum of the nucleus at resonance. In the case of proton imaging, the line broadening dominates the small chemical shifts and the spectral lines are not resolved. This is not ...

journal_title：Investigative radiology

authors： Harrison CG,Adams DF,Kramer PB

更新日期：1985-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Low-field magnetic resonance imaging (MRI) evaluation of breast implants is described, with emphasis on the capabilities provided by different imaging sequences. METHODS:Open architecture MR images using a .064-T permanent magnet and three-dimensional Fourier transform and inversion recovery s...

journal_title：Investigative radiology

authors： Frankel S,Occhipinti K,Kaufman L,Kramer D,Carlson J,Mineyev M,Friedenthal R

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:The safety of nonionic contrast agents with that of ionic iodinated contrast agents in children is compared. METHODS:A comprehensive literature search was conducted to identify all publications on the safety profile of nonionic contrast agents administered intravenously to children. This information was com...

journal_title：Investigative radiology

authors： Cohen MD

更新日期：1993-11-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...

journal_title：Investigative radiology

authors： Chaabane L,Soulas EC,Contard F,Salah A,Guerrier D,Briguet A,Douek P

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...

journal_title：Investigative radiology

authors： Ladwig M,Flemming B,Seeliger E,Sargsyan L,Persson PB

更新日期：2011-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the use of a new thrombus-specific ultrasound contrast agent, MRX-408, in the ultrasonic detection of thrombus in arteriovenous (AV) fistulae. METHODS:Six purpose-bred mongrels with two AV fistulae each were imaged with gray-scale ultrasound 7 weeks after graft implantation before ...

journal_title：Investigative radiology

authors： Unger E,Metzger P 3rd,Krupinski E,Baker M,Hulett R,Gabaeff D,Mills J,Ihnat D,McCreery T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To investigate three-echo T2*-corrected Dixon magnetic resonance imaging (MRI) for noninvasively estimating hepatic fat content (HFC) compared with biopsy. MATERIALS AND METHODS:One hundred patients (50 men, 50 women; mean age, 57.7±14.2 years) underwent clinically indicated liver core biopsy (102 valid tiss...

journal_title：Investigative radiology

authors： Kühn JP,Evert M,Friedrich N,Kannengiesser S,Mayerle J,Thiel R,Lerch MM,Dombrowski F,Mensel B,Hosten N,Puls R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To quantify independent pharmacokinetic parameters for differentiation of prostate pathology. MATERIAL AND METHODS:Twenty-seven patients with biopsy-proven prostate cancer (PSA: 1.4-16.1 ng/mL) underwent magnetic resonance imaging with a new dynamic contrast-enhanced, inversion-prepared dual-contrast gradien...

journal_title：Investigative radiology

authors： Franiel T,Lüdemann L,Rudolph B,Rehbein H,Staack A,Taupitz M,Prochnow D,Beyersdorff D

更新日期：2008-07-01 00:00:00

abstract：:The rates at which the paramagnetic compounds deoxyhemoglobin (Hb) and methemoglobin (MHb) form in vivo within an area of hemorrhage are unknown. The present experiment establishes the baseline concentrations and rates of change in paramagnetic hemoglobin concentrations, as well as the pH in normal heparinized and clo...

journal_title：Investigative radiology

authors： Taber KH,Migliore PJ,Pagani JJ,Ford JJ,McLauren T,Hayman LA

更新日期：1990-03-01 00:00:00