Semiquantitative assessment of myocardial perfusion using magnetic resonance imaging: evaluation of appropriate thresholds and segmentation models.

abstract：PURPOSE:The aim was to investigate the feasibility and image quality of prospective respiratory gating for 3-D computed tomography (CT) of the lung. MATERIAL AND METHODS:Eight anesthetized pigs underwent prospectively gated multidetector computed tomography using 2 devices: a charge-coupled device (CCD) camera and a l...

journal_title：Investigative radiology

authors： Zaporozhan J,Ley S,Unterhinninghofen R,Saito Y,Fabel-Schulte M,Keller S,Szabo G,Kauczor HU

更新日期：2006-05-01 00:00:00

abstract：:Gastrografin and Amipaque with identical iodine content and flavoring were orally administered in 100 ml doses to 10 healthy volunteers in a double-blind crossover study. The nonionic Amipaque has only about one third of the osmolality of Gastrografin, and draws less fluid into the bowel lumen. Consequently there is l...

journal_title：Investigative radiology

authors： Johansen JG

更新日期：1978-11-01 00:00:00

abstract：:Radiolabeled ioversol was injected intravenously into two male and two female beagle dogs (6.7 to 10.4 kg) at two dose levels each (0.2 and 1.0 g I/kg). Blood levels of radioactivity were monitored at 2, 5, 10, 20, 40, 60, 90, and 120 minutes and at one and two days. Urine and feces were collected in metabolism cages ...

journal_title：Investigative radiology

authors： Coveney JR,Robbins MS

更新日期：1989-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the feasibility of a prototype volume-interpolated breath-hold examination (VIBE) sequence using compressed sensing (VIBECS) for rapid multiphase arterial magnetic resonance imaging (MRI) at different temporal resolution during free-breathing in comparison with a convention...

journal_title：Investigative radiology

authors： Weiss J,Notohamiprodjo M,Taron J,Martirosian P,Nickel D,Bamberg F,Nikolaou K,Othman AE

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF) has been related to the use of gadolinium-based contrast agents (GBCAs) in patients undergoing dialysis. The Prospective Fibrose Nephrogénique Systémique study, a French prospective study supported by the French drug regulatory agency (Agence Nationale de Sécurité du Médic...

journal_title：Investigative radiology

authors： Amet S,Launay-Vacher V,Clément O,Frances C,Tricotel A,Stengel B,Gauvrit JY,Grenier N,Reinhardt G,Janus N,Choukroun G,Laville M,Deray G

更新日期：2014-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The aim of the study was to examine the effects of azelastine on proliferation, clonogenic activity, cell-cycle, and migration of human aortic smooth-muscle cells (haSMCs) in vitro. METHODS:HaSMCs were treated for 4 days with azelastine (1 micromol/L, 25 micromol/L, 50 micromol/L). Half of the...

journal_title：Investigative radiology

authors： Schöber W,Wiskirchen J,Kehlbach R,Gebert R,Rodegerdts E,Betsch A,Johst U,Feuls R,Claussen CD,Duda SD

更新日期：2002-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Diabetic patients frequently suffer contrast media-induced nephropathy. Hyperglycemia in diabetes mellitus causes gradual deterioration of glomerular mesangial cells (MCs) in the kidney. In this study, the authors investigated the response of rat MCs cultured in high-glucose medium to diatrizoa...

journal_title：Investigative radiology

authors： Wasaki M,Sugimoto J,Shirota K

更新日期：2001-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new animal model for the evaluation of the renal tolerance of contrast agent and its application to diatrizoate and iotrolan injections in comparison to saline and mannitol solution. MATERIALS AND METHODS:The nephrotoxic potential of intravenously injected contrast agents in Beagl...

journal_title：Investigative radiology

authors： Krause W,Gilles T

更新日期：2003-11-01 00:00:00

abstract：:Gadolinium was attached to antibodies and tested in vitro and in vivo for its effect on proton relaxation enhancement. Using the cyclic anhydride method, diethylenetriaminepentaacetic acid (DTPA) was attached to albumin, IgG and anti-CEA monoclonal antibody. Gadolinium (Gd) was then chelated to the protein complexes f...

journal_title：Investigative radiology

authors： Unger EC,Totty WG,Neufeld DM,Otsuka FL,Murphy WA,Welch MS,Connett JM,Philpott GW

更新日期：1985-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The reflux of ethanol into the peritoneal cavity during percutaneous ethanol injection therapy (PEIT) of liver neoplasms may cause pain and other side effects. This article studies the optimal injection technique to minimize the reflux of ethanol. METHODS:A technique using normal postmortem pi...

journal_title：Investigative radiology

authors： Vehmas T

更新日期：1992-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether gadolinium-ethoxybenzyl-DTPA (Gd-EOB-DTPA) can be eliminated in the absence of the two usual excretory pathways (urinary or biliary) and whether a remaining excretory pathway is able to compensate for impaired liver or kidney function. METHODS:The study was per...

journal_title：Investigative radiology

authors： Mühler A,Heinzelmann I,Weinmann HJ

更新日期：1994-02-01 00:00:00

abstract：:A method is presented for selective catheterization and filming of the small internal spermatic and proper hepatic arteries in rabbits. The angiograms thus obtained afford clear delineation of the vessels and their branches and can enhance radiographic investigation of a variety of experimental disease models. ...

journal_title：Investigative radiology

authors： Young S,Hollenberg NK

更新日期：1977-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors developed a two-dimensional breathhold magnetic resonance (MR) technique for the direct imaging of pulmonary emboli. METHODS:In vitro MR imaging was performed to demonstrate the potential generation of clot-blood contrast by in vivo pulmonary embolism (PE). A two-dimensional magnet...

journal_title：Investigative radiology

authors： Moody AR,Liddicoat A,Krarup K

更新日期：1997-08-01 00:00:00

abstract：:French physicians must obtain their patient's consent before carrying out an action that interferes with the patient's corporal integrity. The doctor must use simple, approximate, intelligent, and honest words that help the patient to reach the indispensable decision. Proof of lack of consent lies with the patient. Th...

journal_title：Investigative radiology

authors： Alméras JP,Husson R,Moreau JF

更新日期：1988-09-01 00:00:00

abstract：:The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of the...

journal_title：Investigative radiology

authors： Klibanov AL

更新日期：2006-03-01 00:00:00

abstract：:In order to measure the accuracy of a diagnostic imaging technique, the correctness of each observer decision must be determined. This is often difficult in clinical cases, and various strategies are frequently used to approximate the truth. Experiments using chest radiographs as an example are reported to show the pi...

journal_title：Investigative radiology

authors： Revesz G,Kundel HL,Bonitatibus M

更新日期：1983-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sonographic appearance. In a...

journal_title：Investigative radiology

authors： Mäurer J,Willam C,Steinkamp HJ,Knollmann FD,Felix R

更新日期：1996-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the abilities of dynamic diffusion-weighted MRI to demonstrate the effects in vivo of a high-viscosity iodinated contrast agent on medullary and cortical blood flow in the rat kidney. METHODS:Dynamic diffusion-weighted, echoplanar MR images obtained from five b-value single-shot acqu...

journal_title：Investigative radiology

authors： Laissy JP,Menegazzo D,Dumont E,Piekarski JD,Karila-Cohen P,Chillon S,Schouman-Claeys E

更新日期：2000-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the use of a new thrombus-specific ultrasound contrast agent, MRX-408, in the ultrasonic detection of thrombus in arteriovenous (AV) fistulae. METHODS:Six purpose-bred mongrels with two AV fistulae each were imaged with gray-scale ultrasound 7 weeks after graft implantation before ...

journal_title：Investigative radiology

authors： Unger E,Metzger P 3rd,Krupinski E,Baker M,Hulett R,Gabaeff D,Mills J,Ihnat D,McCreery T

更新日期：2000-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate postmortem metabolic and morphologic alterations in the dog brain thalamus and to contribute diagnostic aids in medicolegal science. METHODS:A homogeneous group of 17 dogs was used for in vivo 1H magnetic resonance (MR) spectroscopy and electron microscopic studies, which were p...

journal_title：Investigative radiology

authors： Choe BY,Gil HJ,Suh TS,Shinn KS

更新日期：1995-05-01 00:00:00

abstract：:A silicone gel phantom material is described. It can be molded into any shape and it can contain internal cavities. The material is selfsealing allowing the cavities to be filled with liquids. A simple geometric phantom consisting of a rectangular solid with a single internal spherical cavity was fabricated and imaged...

journal_title：Investigative radiology

authors： Goldstein DC,Kundel HL,Daube-Witherspoon ME,Thibault LE,Goldstein EJ

更新日期：1987-02-01 00:00:00

abstract：:The large intestines of eight boxer dogs with canine histiocytic ulcerative colitis (CHUC) and 10 normal dogs were studied by in vivo angiography and postmortem microangiography. The vascular abnormalities were correlated with the gross and histologic pathology found at necropsy. The angiographic abnormalities were ...

journal_title：Investigative radiology

authors： Lawson TL,Gomez JA,Margulis AR

更新日期：1975-05-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...

journal_title：Investigative radiology

authors： Runge VM,Williams NM,Lee C,Timoney JF

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

journal_title：Investigative radiology

authors： Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

更新日期：2015-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A computerized system that applies the case-based approach to training radiologists to diagnose brain tumors was designed. The authors attempted to provide residents a tool that supports their visual memory and inducts case-based reasoning. METHODS:A relational database with a digital image li...

journal_title：Investigative radiology

authors： Macura RT,Macura KJ,Toro VE,Binet EF,Trueblood JH,Ji K

更新日期：1994-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

journal_title：Investigative radiology

authors： Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

更新日期：1995-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the influence of injection rates and volumes on the arrival time of contrast material (CM) in the common carotid artery, the jugular vein and the resulting arterial-venous transit time. Additionally the relationship between injection parameters and the extent of a CM plateau was evalu...

journal_title：Investigative radiology

authors： Herold T,Paetzel C,Völk M,Bachthaler M,Zorger N,Feuerbach S,Strotzer M,Lenhart M

更新日期：2004-02-01 00:00:00

abstract：:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

journal_title：Investigative radiology

authors： Gould RG

更新日期：1992-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the effect of contrast dose, use of magnetization transfer (MT), and temporal delay on the visualization of contrast enhancement with gadoteridol (Gd HP-DO3A) in a canine brain abscess model. METHODS:Alpha streptococcus brain abscesses were studied in five dogs at 1.5 tesla...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Kirsch JE

更新日期：1995-03-01 00:00:00

abstract：:The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

journal_title：Investigative radiology

authors： Roberts JG,DiTomasso E,Webber CE

更新日期：1982-01-01 00:00:00