Antiproliferative effects of the antiallergic agent azelastine on human aortic smooth-muscle cells: an in vitro study.

abstract：INTRODUCTION:Attenuation correction for magnetic resonance (MR) coils is a new challenge that came about with the development of combined MR and positron emission tomography (PET) imaging. This task is difficult because such coils are not directly visible on either PET or MR acquisitions with current combined scanners ...

journal_title：Investigative radiology

authors： Eldib M,Bini J,Calcagno C,Robson PM,Mani V,Fayad ZA

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare qualitative and quantitative image quality and geometric distortion of 4 magnetic resonance diffusion-weighted imaging (DWI) sequences of the prostate using comparable imaging parameters and similar acquisition times. METHODS AND MATERIALS:Axial T2-weighted turbo spin echo ...

journal_title：Investigative radiology

authors： Stocker D,Manoliu A,Becker AS,Barth BK,Nanz D,Klarhöfer M,Donati OF

更新日期：2018-04-01 00:00:00

abstract：:The effect of contrast media (CM) dilution on contrast enhancement was studied using CM representing four structurally different molecular types at osmolalities ranging from 135 to 1340 mosm/kg. Diatrizoate (ionic monomer), iopamidol (nonionic monomer), ioxaglate (ionic dimer), and iodecol (nonionic dimer) were each g...

journal_title：Investigative radiology

authors： Dean PB,Kivisaari L,Kormano M

更新日期：1988-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors assessed whether a non-sleep-deprived, second-year diagnostic radiology resident assigned to an after-hours "night stalker" emergency radiology (ER) rotation in an urban university hospital has a measurable impact on the number and clinical significance of "missed" radiologic findin...

journal_title：Investigative radiology

authors： Mann FA,Danz PL

更新日期：1993-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors analyze the origins of the "clotting issue," the controversy that began in the 1980s when contrast media, once perceived as good flushing agents for catheters because of their assumed anticoagulant properties, came under attack for allegedly causing thromboembolism. Laboratory studi...

journal_title：Investigative radiology

authors： Dawson P,Cousins C,Bradshaw A

更新日期：1993-11-01 00:00:00

abstract：:Radiation dose in computed tomography (CT) has become a hot topic due to an upward trend in the number of CT procedures worldwide and the relatively high doses associated with these procedures. The main aim of this review article is to provide an overview of the most frequently used metrics for CT radiation dose chara...

journal_title：Investigative radiology

authors： Damilakis J

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess whether fluorochrome-coupled bacterial magnetic nanoparticles can be used as bimodal contrast agent for both magnetic resonance imaging (MRI) and near-infrared fluorescence optical (NIRF) imaging of cultured macrophages. MATERIALS AND METHODS:Bacterial magnetic nanopa...

journal_title：Investigative radiology

authors： Lisy MR,Hartung A,Lang C,Schüler D,Richter W,Reichenbach JR,Kaiser WA,Hilger I

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...

journal_title：Investigative radiology

authors： Tokuda J,Wang Q,Tuncali K,Seethamraju RT,Tempany CM,Schmidt EJ

更新日期：2020-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To present the results of two studies conducted to evaluate the pharmacokinetics and safety of iomeprol in healthy volunteers and in patients with various degrees of renal impairment. METHODS:In these two open-label, single-dose, phase I studies, a 50-mL dose of iomeprol 400 was administered i...

journal_title：Investigative radiology

authors： Lorusso V,Taroni P,Alvino S,Spinazzi A

更新日期：2001-06-01 00:00:00

abstract：:Arterial occlusion by direct-current transcatheter electrocoagulation (TCEC) has been developed experimentally and used successfully in clinical situations. The major shortcoming of the technique has been the lengthy time necessary for occlusion of larger arteries. In the present study we attempted to decrease the tim...

journal_title：Investigative radiology

authors： Ralston MD,Woodfield S,Halvorsen R,Pizzo SV,Thompson WM

更新日期：1982-03-01 00:00:00

abstract：:The developing trend for all medical images to be in digital form raises an important question: should diagnostic interpretations be made directly from a CRT or from some form of hard copy recording of the CRT? This question was studied by having two observers read a series of digital images of the thyroid including b...

journal_title：Investigative radiology

authors： Keyes JW Jr,Kline RC,Resinger WW,Rose EA,Koral KF,Rogers WL

更新日期：1983-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The reflux of ethanol into the peritoneal cavity during percutaneous ethanol injection therapy (PEIT) of liver neoplasms may cause pain and other side effects. This article studies the optimal injection technique to minimize the reflux of ethanol. METHODS:A technique using normal postmortem pi...

journal_title：Investigative radiology

authors： Vehmas T

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:With the introduction of ultrashort echo time (UTE) sequences solid polymeric materials might become visible on clinical whole-body magnetic resonance (MR) scanners. The aim of this study was to characterize solid polymeric materials typically used for instruments in magnetic resonance guided interventions an...

journal_title：Investigative radiology

authors： Springer F,Martirosian P,Schwenzer NF,Szimtenings M,Kreisler P,Claussen CD,Schick F

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate the safety and efficacy of combined unenhanced and gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging compared with unenhanced MR imaging and triphasic contrast-enhanced spiral computed tomography (CT) for the detection and characterization of focal liver...

journal_title：Investigative radiology

authors： Ichikawa T,Saito K,Yoshioka N,Tanimoto A,Gokan T,Takehara Y,Kamura T,Gabata T,Murakami T,Ito K,Hirohashi S,Nishie A,Saito Y,Onaya H,Kuwatsuru R,Morimoto A,Ueda K,Kurauchi M,Breuer J

更新日期：2010-03-01 00:00:00

abstract：:The association of GE Medical Systems and the AUR represents a unique collaboration between academic radiology and industry that bears important potential for elevating the quality of clinical research in radiology and developing a cadre of high-quality radiologist researchers for the future. The establishment of the ...

journal_title：Investigative radiology

authors： Hillman BJ,Fryback DG,Holden RW,McNeil BJ,Molitor RM,Moss AA,Peck PV,Putman CE,Thompson WM

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...

journal_title：Investigative radiology

authors： Kettenbach J,Kronreif G,Figl M,Fürst M,Birkfellner W,Hanel R,Ptacek W,Bergmann H

更新日期：2005-04-01 00:00:00

abstract：:Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

journal_title：Investigative radiology

authors： Cuttino JT Jr,Goss FU,Clark RL,Marr MC

更新日期：1981-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...

journal_title：Investigative radiology

authors： Grimm J,Karger N,Lüsse S,Winoto-Morbach S,Krisch B,Müller-Hülsbeck S,Heller M

更新日期：2000-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS:Recordings were obtai...

journal_title：Investigative radiology

authors： Kok T,Slooff MJ,Peeters PM,Zwaveling JH,Bijleveld CM,Gi-van Loon CE,Klompmaker IJ,Haagsma EB

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effects of gadolinium (Gd3+), provided as gadolinium chloride, on fibroblast function. MATERIALS AND METHODS:Human dermal fibroblasts in monolayer culture and intact skin in organ culture were exposed to the lanthanide metal (1-20 μM). RESULTS:Increased proliferat...

journal_title：Investigative radiology

authors： Bhagavathula N,Dame MK,DaSilva M,Jenkins W,Aslam MN,Perone P,Varani J

更新日期：2010-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:High signal intensity in the basal ganglia on T1-weighted MR imaging has been reported in chronic manganese (Mn) poisoning. However, the exact meaning of the high signal intensity remains unclear: does it result from Mn itself, secondary pathologic changes of the brain tissue, or both? The goal...

journal_title：Investigative radiology

authors： Kim SH,Chang KH,Chi JG,Cheong HK,Kim JY,Kim YM,Han MH

更新日期：1999-06-01 00:00:00

abstract：:Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...

journal_title：Investigative radiology

authors： Griffith SL,Burney BT,Fry FJ,Franklin TD Jr

更新日期：1989-02-01 00:00:00

abstract：:A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours be...

journal_title：Investigative radiology

authors： Lasser EC,Berry CC,Talner LB,Santini LC,Lang EK,Gerber FH,Stolberg HO

更新日期：1988-09-01 00:00:00

abstract：:A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

journal_title：Investigative radiology

authors： Sovak M,Siefert HM,Ranganathan R

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Multidetector-row computed tomography coronary images are usually analyzed in mid-diastole (MD). Because of slow coronary motion also in end-systole (ES), we evaluated the impact on image quality of including ES images and defined an efficient reconstruction protocol. MATERIAL AND METHODS:In 50 coronary mul...

journal_title：Investigative radiology

authors： Sanz J,Rius T,Kuschnir P,Fuster V,Goldberg J,Ye XY,Wisdom P,Poon M

更新日期：2005-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the potential of magnetic resonance imaging (MRI) for evaluating the evolution of tumor necrosis, the authors evaluated 28 VX2 carcinomas inoculated in the thigh muscles of rabbits. METHODS:MRI of VX2 carcinomas at 2.0 T was done with spin-echo technique 1 week (14 tumors) and 3 week...

journal_title：Investigative radiology

authors： Choi BI,Lee DH,Han MC

更新日期：1993-01-01 00:00:00

abstract：:Due to the nature of three-dimensional Fourier transform (3-DFT) data acquisition in magnetic resonance imaging (MRI), the spatial relation between a resolved volume element (a voxel) and the object can be manipulated easily. Those manipulations have practical consequences in terms of registering slice positions with ...

journal_title：Investigative radiology

authors： Kramer D,Li A,Simovsky I,Hawryszko C,Hale J,Kaufman L

更新日期：1990-12-01 00:00:00

abstract：:The cerebrovascular toxicity of three water-soluble contrast agents with a low hypertonicity (metrizamide, ioxaglate, iopamidol) was tested. Blood-brain barrier damage after carotid injection was assessed using 32P autoradiography and fluorescent microscopy after Evans blue staining. The damage to carotid endothelium ...

journal_title：Investigative radiology

authors： Gonsette RE,Liesenborgh L

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess and compare the overall performance, reliability, variability, as well as the accuracy of diffusion tensor imaging (DTI) and fiber tracking metrics, for the muscles of the calf at 3 T and 7 T. MATERIALS AND METHODS:Ten volunteers (5 males; mean age, 29.1 ± 4.7 years), with...

journal_title：Investigative radiology

authors： Giraudo C,Motyka S,Weber M,Feiweier T,Trattnig S,Bogner W

更新日期：2019-01-01 00:00:00