Postmortem metabolic and morphologic alterations of the dog brain thalamus with use of in vivo 1H magnetic resonance spectroscopy and electron microscopy.

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether gadolinium-ethoxybenzyl-DTPA (Gd-EOB-DTPA) can be eliminated in the absence of the two usual excretory pathways (urinary or biliary) and whether a remaining excretory pathway is able to compensate for impaired liver or kidney function. METHODS:The study was per...

journal_title：Investigative radiology

authors： Mühler A,Heinzelmann I,Weinmann HJ

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:There is little published information regarding the efficacy of paclitaxel-coated balloon catheters except for the iopromide-containing formulation, and less is known about the kind of toxicity at overdose. The aim of our study was to assess 2 different paclitaxel matrix formulations on angioplasty balloon ca...

journal_title：Investigative radiology

authors： Kelsch B,Scheller B,Biedermann M,Clever YP,Schaffner S,Mahnkopf D,Speck U,Cremers B

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS:Ten pat...

journal_title：Investigative radiology

authors： Freedman JN,Collins DJ,Bainbridge H,Rank CM,Nill S,Kachelrieß M,Oelfke U,Leach MO,Wetscherek A

更新日期：2017-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00

abstract：:The biliary and urinary excretion of sodium tyropanoate (Bilopaque) and sodium ipodate (Oragrafin) were studied in unanesthetized bile-fistula dogs using stepwise, increasing, intravenous infusions of the contrast materials. A constant intravenous infusion of sodium taurocholate was administered at the rate of either ...

journal_title：Investigative radiology

authors： Berk RN,Loeb PM,Cobo-Frenkel A,Barnhart JL

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate and validate quantitative susceptibility mapping (QSM) for lesional iron quantification in cerebral cavernous malformations (CCMs). MATERIALS AND METHODS:Magnetic resonance imaging studies were performed in phantoms and 16 patients on a 3-T scanner. Susceptibility ...

journal_title：Investigative radiology

authors： Tan H,Liu T,Wu Y,Thacker J,Shenkar R,Mikati AG,Shi C,Dykstra C,Wang Y,Prasad PV,Edelman RR,Awad IA

更新日期：2014-07-01 00:00:00

abstract：:Comparatively new in the roentgen evaluation of infants and children, xerography would appear to be ideal for portraying the pediatric airway. Since the radiation dose of xerography is higher than conventional radiography, its image quality is the subject of careful scrutiny in a pediatric setting here described in 23...

journal_title：Investigative radiology

authors： Scott JR,Kramer SS,Griscom NT

更新日期：1978-07-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...

journal_title：Investigative radiology

authors： Runge VM,Williams NM,Lee C,Timoney JF

更新日期：1998-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a simple and robust helium3 polarization system dedicated to small animal imaging. To demonstrate the potential of helium3 imaging for pulmonary ventilation and perfusion studies. METHODS:A home-built polarization system based on spin-exchange technique was used. This system was app...

journal_title：Investigative radiology

authors： Stupar V,Berthezène Y,Canet E,Tournier H,Dupuich D,Crémillieux Y

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：:The Point Spread Function (PSF) in NMR imaging is the result of both the line broadening due to magnet field inhomogeneity and the intrinsic spectrum of the nucleus at resonance. In the case of proton imaging, the line broadening dominates the small chemical shifts and the spectral lines are not resolved. This is not ...

journal_title：Investigative radiology

authors： Harrison CG,Adams DF,Kramer PB

更新日期：1985-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A new hepatobiliary gadolinium chelate, gadolinium (Gd) 2,5-BPA-DO3A, was compared in two animal species with Gd HP-DO3A (gadoteridol), a clinically approved extracellular contrast agent, and Gd Cy2-DOTA, a second hepatobiliary chelate in preclinical development. The ligand in Gd 2,5-BPA-DO3A i...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Williams NM

更新日期：1996-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...

journal_title：Investigative radiology

authors： Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:The relaxivities of 3 macrocyclic gadolinium-based contrast agents (GBCAs) were determined in human plasma and blood under standardized and clinically relevant laboratory conditions. METHODS:The T1 relaxivity, r1, was determined in human plasma at 1.5, 3, and 7 T, and in human blood at 3 T at 37°C in phantoms ...

journal_title：Investigative radiology

authors： Szomolanyi P,Rohrer M,Frenzel T,Noebauer-Huhmann IM,Jost G,Endrikat J,Trattnig S,Pietsch H

更新日期：2019-09-01 00:00:00

abstract：:Observer performance in radiologic interpretation has traditionally been based upon Receiver Operating Characteristic (ROC) analysis. A statistical method that evaluates the reproducibility or consistency of radiologic interpretation is presented. Since this method is not based upon pathologic verification, it cannot ...

journal_title：Investigative radiology

authors： Herman S,DeBoer G,Rideout DF,Majesky IF

更新日期：1984-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study sought to evaluate prospectively the diagnostic potential of unenhanced and enhanced color Doppler and power Doppler for the differentiation of tumors and tumorlike lesions of the breast. METHODS:Ninety-two patients with 110 tumors or tumorlike lesions of the breast were investigate...

journal_title：Investigative radiology

authors： Schroeder RJ,Maeurer J,Vogl TJ,Hidajat N,Hadijuana J,Venz S,Weber S,Felix R

更新日期：1999-02-01 00:00:00

abstract：:We evaluated the density distribution (anterior-posterior) of the right lung in 19 acutely anesthetized supine dogs using computed transmission tomography (CTT). Eleven dogs served as controls, and eight received 0.12 cc/kg of intravenously administered oleic acid. The latter were sequentially imaged over 1 hour. Nine...

journal_title：Investigative radiology

authors： Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...

journal_title：Investigative radiology

authors： Bun SS,Kober F,Jacquier A,Espinosa L,Kalifa J,Bonzi MF,Kopp F,Lalevee N,Zaffran S,Deharo JC,Cozzone PJ,Bernard M

更新日期：2012-05-01 00:00:00

abstract：:The purpose of our investigation was to determine whether iopanoyl glucuronide, the major metabolite of iopanoic acid (Telepaque), undergoes hydrolysis by bacterial beta-glucuronidase in dogs. The conjugated compound was identified and quantitated by elemental analysis, fluorescent excitation analysis, thin-layer chro...

journal_title：Investigative radiology

authors： Thoeni RF,Goldberg HI,Moss AA,Lin SK,Brito AC

更新日期：1978-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new animal model for the evaluation of the renal tolerance of contrast agent and its application to diatrizoate and iotrolan injections in comparison to saline and mannitol solution. MATERIALS AND METHODS:The nephrotoxic potential of intravenously injected contrast agents in Beagl...

journal_title：Investigative radiology

authors： Krause W,Gilles T

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...

journal_title：Investigative radiology

authors： Tokuda J,Wang Q,Tuncali K,Seethamraju RT,Tempany CM,Schmidt EJ

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the feasibility of a prototype volume-interpolated breath-hold examination (VIBE) sequence using compressed sensing (VIBECS) for rapid multiphase arterial magnetic resonance imaging (MRI) at different temporal resolution during free-breathing in comparison with a convention...

journal_title：Investigative radiology

authors： Weiss J,Notohamiprodjo M,Taron J,Martirosian P,Nickel D,Bamberg F,Nikolaou K,Othman AE

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:To determine the reproducibility, accuracy, and predictors of accuracy of computed tomography (CT) angiography to detect and characterize coronary atherosclerotic plaque as compared with intravascular ultrasound. METHODS:Ten ex vivo human coronary arteries were imaged in a moving phantom by dual-source CT (col...

journal_title：Investigative radiology

authors： van der Giessen AG,Toepker MH,Donelly PM,Bamberg F,Schlett CL,Raffle C,Irlbeck T,Lee H,van Walsum T,Maurovich-Horvat P,Gijsen FJ,Wentzel JJ,Hoffmann U

更新日期：2010-11-01 00:00:00

abstract：:Surgical resection is the standard of care for colorectal metastases isolated to the liver. However, only 10-25% of the patients are eligible for resection because of extent and location of the disease in the liver or concurrent medical conditions. Image-guided radiofrequency (RF) ablation is a minimally invasive tech...

journal_title：Investigative radiology

authors： Lencioni R,Crocetti L,Cioni D,Della Pina C,Bartolozzi C

更新日期：2004-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vascular opacification characteristics of a new nonionic, dimeric contrast agent, iodixanol, have been compared with a nonionic, monomeric agent, iohexol, using ultrafast computed tomography (UFCT). METHODS:In 10 experiments with mongrel dogs, the contrast agents were alternately injected ...

journal_title：Investigative radiology

authors： Gould R,Brasch RC,Sievers R,Baxter A,Aicher K

更新日期：1992-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors determine the relative effect of soft-tissue compartments, body fat (percent [%Bfat] and weight [Bfat kg]) and fat-free mass (FFM kg), on measurements of ultrasound bone velocity (UBV m/second). METHODS:The authors measured UBV in proximal phalanxes and body fat and fat-free mass b...

journal_title：Investigative radiology

authors： Gómez M,Aguado F,Manuel J,Menéndez JM,Revilla M,Villa LF,Cortés J,Rico H

更新日期：1997-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to identify the signal intensity (SI) changes in the dentate nucleus (DN) and the globus pallidus (GP) on unenhanced T1-weighted magnetic resonance (MR) images after multiple administration of gadolinium-based contrast agents (GBCAs) in children and compare those changes between linear...

journal_title：Investigative radiology

authors： Ryu YJ,Choi YH,Cheon JE,Lee WJ,Park S,Park JE,Kim WS,Kim IO

更新日期：2018-04-01 00:00:00

abstract：:The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...

journal_title：Investigative radiology

authors： Kelly RB,Mahoney PD,Frick MP

更新日期：1987-07-01 00:00:00

abstract：:The contrast sensitivity of the retina is greatest in the center and decreases rapidly toward the periphery. Therefore, the detection of low-contrast lung nodules depends upon the manner in which the image is sampled by retinal receptors as eye fixations jump across the image during scanning. The scanning performance ...

journal_title：Investigative radiology

authors： Kundel HL,Nodine CF,Thickman D,Toto L

更新日期：1987-05-01 00:00:00

abstract：:The rates at which the paramagnetic compounds deoxyhemoglobin (Hb) and methemoglobin (MHb) form in vivo within an area of hemorrhage are unknown. The present experiment establishes the baseline concentrations and rates of change in paramagnetic hemoglobin concentrations, as well as the pH in normal heparinized and clo...

journal_title：Investigative radiology

authors： Taber KH,Migliore PJ,Pagani JJ,Ford JJ,McLauren T,Hayman LA

更新日期：1990-03-01 00:00:00