Computerized case-based instructional system for computed tomography and magnetic resonance imaging of brain tumors.

abstract：OBJECTIVE:The purpose of this study was to assess the effects of gadolinium (Gd3+), provided as gadolinium chloride, on fibroblast function. MATERIALS AND METHODS:Human dermal fibroblasts in monolayer culture and intact skin in organ culture were exposed to the lanthanide metal (1-20 μM). RESULTS:Increased proliferat...

journal_title：Investigative radiology

authors： Bhagavathula N,Dame MK,DaSilva M,Jenkins W,Aslam MN,Perone P,Varani J

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00

abstract：:We examined the acute systemic and renal hemodynamic effects of intravenous meglumine/sodium diatrizoate-76% and iopamidol in euvolemic and dehydrated dogs. The physiologic responses were compared with acute changes in the level of an endogenous heparin-like material (EHM). One of eight dehydrated dogs receiving diatr...

journal_title：Investigative radiology

authors： Katzberg RW,Morris TW,Lasser EC,DiMarco PL,Merguerian PA,Ventura JA,Pabico RC,McKenna BA

更新日期：1986-10-01 00:00:00

abstract：:Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...

journal_title：Investigative radiology

authors： Burbank FH,Thompson WM

更新日期：1986-03-01 00:00:00

abstract：:Video dilution technique (VDT) is currently performed in conjunction with routine cerebral angiography to determine carotid blood flow in humans. Preliminary results indicate that the blood flows (as a percentage of cardial output) of the common, internal, and external carotid arteries are 8.5%, 5.5%, and 3.0%, respec...

journal_title：Investigative radiology

authors： Lantz BM,Dublin AB,McGahan JP,Link DP

更新日期：1981-05-01 00:00:00

abstract：OBJECTIVES:Over the recent years, there have been increasing concerns that exposure to gadolinium-based contrast agents (GBCAs) may be associated with retention of Gd within the skin, bones, and solid organs in patients with normal renal function, although the clinical implications of this deposition remain to be estab...

journal_title：Investigative radiology

authors： Layne KA,Wood DM,Dixon-Zegeye M,Archer JRH,Raja K,Dargan PI

更新日期：2020-07-01 00:00:00

abstract：:An agent has been identified in lymph from rat kidneys rendered ischemic by partial renal artery occlusion that induces a striking neovascular response in a hamster cheek-pouch assay system. The factor has a high molecular weight, cannot be identified in lymph from normal kidneys, and is associated with a marked incre...

journal_title：Investigative radiology

authors： Hollenberg NK,Paskins-Hurlburt AJ,Abrams HL

更新日期：1985-01-01 00:00:00

abstract：:The results of an in vitro mixed hemadsorption (MHA) assay predicted the success of in vivo tumor localization using a radioiodinated, monoclonal, IgG1 antibody (A2) with reactivity to the human bladder carcinoma cell line RT4. In vitro, murine monoclonal antibodies A2 and G6, demonstrated reactivity to RT4 with titer...

journal_title：Investigative radiology

authors： Gross MD,Skinner RW,Grossman HB

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:We aimed to assess whether migraine is associated with changes in the distribution of the venous drainage through primary and secondary pathways by using phase-contrast magnetic resonance imaging (MRI). METHODS:We examined 26 patients (37.3 ± 13.9 years) with recurring migraine headaches and 26 age- and gend...

journal_title：Investigative radiology

authors： Koerte IK,Schankin CJ,Immler S,Lee S,Laubender RP,Grosse C,Eftimov L,Milde-Busch A,Reiser M,Straube A,Heinen F,Alperin N,Ertl-Wagner B

更新日期：2011-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance microscopy (MRM) has evolved from a technical curiosity to a tool with which researchers can study important disease models. But MRM is not simply an extension of clinical magnetic resonance imaging. In this article, the unique adaptations of MRM required in the study of caro...

journal_title：Investigative radiology

authors： Arnder L,Zhou X,Cofer GP,Hedlund LW,Johnson GA

更新日期：1994-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the use of a new thrombus-specific ultrasound contrast agent, MRX-408, in the ultrasonic detection of thrombus in arteriovenous (AV) fistulae. METHODS:Six purpose-bred mongrels with two AV fistulae each were imaged with gray-scale ultrasound 7 weeks after graft implantation before ...

journal_title：Investigative radiology

authors： Unger E,Metzger P 3rd,Krupinski E,Baker M,Hulett R,Gabaeff D,Mills J,Ihnat D,McCreery T

更新日期：2000-01-01 00:00:00

abstract：:Methods are presented for the quantification of spatial resolution in x-ray computed tomographic (CT) images. Model-dependent methods are derived and compared with model independent methods for computation of the Modulation Transfer Function (MTF). These techniques are applied to phantom images of point, line, edge, a...

journal_title：Investigative radiology

authors： Assimakopoulos PA,Boyd DP,Jaschke W,Lipton MJ

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the feasibility of the combination of magnetic resonance (MR)-guided biopsy (MRGB) and diagnostic 3T MR imaging in the localization of local recurrence of prostate cancer (PCa) after external beam radiation therapy (EBRT). MATERIALS AND METHODS:Twenty-four consecuti...

journal_title：Investigative radiology

authors： Yakar D,Hambrock T,Huisman H,Hulsbergen-van de Kaa CA,van Lin E,Vergunst H,Hoeks CM,van Oort IM,Witjes JA,Barentsz JO,Fütterer JJ

更新日期：2010-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Iopromide is a new monomeric, nonionic contrast agent that exhibits low osmolality and low viscosity in high concentration in aqueous solutions. Double-blind, randomized clinical trials have established the efficacy, safety, and tolerance of iopromide for excretory urography, coronary angiograp...

journal_title：Investigative radiology

authors： Goldberg SN,Abrahams J,Drayer BP,Golding S,Bernardino M,Brunetti J

更新日期：1994-05-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...

journal_title：Investigative radiology

authors： Runge VM,Williams NM,Lee C,Timoney JF

更新日期：1998-04-01 00:00:00

abstract：PURPOSE:To evaluate the dependency of tumor contrast enhancement (CE) in regard to protein-binding properties of contrast agents, using 4 different agents with a wide range of protein-binding capacities in a standardized rat brain glioma model. MATERIAL AND METHODS:Sixteen rats with implanted brain gliomas were evalua...

journal_title：Investigative radiology

authors： Wintersperger BJ,Runge VM,Tweedle MF,Jackson CB,Reiser MF

更新日期：2009-02-01 00:00:00

abstract：:The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

journal_title：Investigative radiology

authors： Roberts JG,DiTomasso E,Webber CE

更新日期：1982-01-01 00:00:00

abstract：:We compared the damage resulting from intradermal injection of four commonly used radiographic contrast media in laboratory rats. Sixty percent meglumine diatrizoate (Reno M 60) and ioxaglate (Hexabrix) produced significantly more ulceration and crusting on gross inspection and more necrosis, edema, and hemorrhage on ...

journal_title：Investigative radiology

authors： Cohan RH,Leder RA,Bolick D,Herzberg AJ,Hedlund LW,Wheeler CT,Helms MJ,Dunnick NR

更新日期：1990-05-01 00:00:00

abstract：:The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...

journal_title：Investigative radiology

authors： Wikström MG,Moseley ME,White DL,Dupon JW,Winkelhake JL,Kopplin J,Brasch RC

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:Transcatheter arterial embolization (TAE) is used for the treatment of patients with malignant liver tumors. However, the proangiogenesis effect of TAE-associated hypoxia has not been adequately studied. The goal of this study was to determine angiogenic activity in tumors subjected to TAE by evaluating the ...

journal_title：Investigative radiology

authors： Gupta S,Kobayashi S,Phongkitkarun S,Broemeling LD,Kan Z

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the potential of quantitative assays of vascular characteristics based on dynamic contrast-enhanced magnetic resonance imaging (MRI) using a macromolecular contrast medium (MMCM) to search for and measure effects of dimethyl sulfoxide (DMSO) on cancer vasculature with microscopic correlations. M...

journal_title：Investigative radiology

authors： Cyran CC,Sennino B,Chaopathomkul B,Fu Y,Rogut V,Shames DM,Wendland MF,McDonald DM,Brasch RC

更新日期：2008-05-01 00:00:00

abstract：:The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...

journal_title：Investigative radiology

authors： Drayer BP,Wolfson SK Jr,Rosenbaum AE,Dujovny M,Boehnke M,Cook EE

更新日期：1979-01-01 00:00:00

abstract：:A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...

journal_title：Investigative radiology

authors： Pitrè D,Felder E

更新日期：1980-11-01 00:00:00

abstract：:Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented. ...

journal_title：Investigative radiology

authors： Enge I

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate if a quantitative evaluation of a magnetic resonance (MR) perfusion examination of the myocardium can achieve a comparable diagnostic accuracy as a semiquantitative evaluation. METHODS:A total of 31 patients with suspected coronary artery disease underwent MR imaging an...

journal_title：Investigative radiology

authors： Huber A,Sourbron S,Klauss V,Schaefer J,Bauner KU,Schweyer M,Reiser M,Rummeny E,Rieber J

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate image quality of a spectral photon-counting detector (PCD) computed tomography (CT) system for evaluation of major arteries of the head and neck compared with conventional single-energy CT scans using energy-integrating detectors (EIDs). METHODS:In this institutional r...

journal_title：Investigative radiology

authors： Symons R,Reich DS,Bagheri M,Cork TE,Krauss B,Ulzheimer S,Kappler S,Bluemke DA,Pourmorteza A

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...

journal_title：Investigative radiology

authors： Radbruch A,Weberling LD,Kieslich PJ,Hepp J,Kickingereder P,Wick W,Schlemmer HP,Bendszus M

更新日期：2015-12-01 00:00:00

abstract：:The biliary and urinary excretion of sodium tyropanoate (Bilopaque) and sodium ipodate (Oragrafin) were studied in unanesthetized bile-fistula dogs using stepwise, increasing, intravenous infusions of the contrast materials. A constant intravenous infusion of sodium taurocholate was administered at the rate of either ...

journal_title：Investigative radiology

authors： Berk RN,Loeb PM,Cobo-Frenkel A,Barnhart JL

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to quantify image quality gains of a moving coronary plaque phantom using dual-source computed tomography (DSCT) providing 83 milliseconds temporal resolution in direct comparison to 64 slice single-source multidetector CT (MDCT) with a temporal resolution of 165 milliseconds. MATE...

journal_title：Investigative radiology

authors： Reimann AJ,Rinck D,Birinci-Aydogan A,Scheuering M,Burgstahler C,Schroeder S,Brodoefel H,Tsiflikas I,Herberts T,Flohr T,Claussen CD,Kopp AF,Heuschmid M

更新日期：2007-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vasoconstriction of the renal arteries is frequently considered as a crucial factor for radiocontrast-induced nephropathy. A direct effect of iodinated radiographic contrast medium (RCM) on vascular smooth muscle is supposed to be one component of the vascular response. We studied the effec...

journal_title：Investigative radiology

authors： Uder M,Humke U,Pahl M,Jansen A,Utz J,Kramann B

更新日期：2002-08-01 00:00:00