Perfusion quantitation by ultrafast computed tomography.

Abstract:

:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acquire data at up to eight cross-sectional levels without moving the patient. Direct application of indicator dilution principles permit measurement of cardiac output and has been validated in both animals and humans. However, measurement of myocardial perfusion, an initial design goal of the UFCT scanner, has been difficult. Experiments in animals have consistently underestimated flow at high flow rates. Methods to improve accuracy include better accounting for tissue blood volume and minimizing image artifacts.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Gould RG

doi

10.1097/00004424-199212002-00004

keywords:

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

S18-21

eissn

0020-9996

issn

1536-0210

journal_volume

27 Suppl 2

pub_type

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