Abstract:
:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acquire data at up to eight cross-sectional levels without moving the patient. Direct application of indicator dilution principles permit measurement of cardiac output and has been validated in both animals and humans. However, measurement of myocardial perfusion, an initial design goal of the UFCT scanner, has been difficult. Experiments in animals have consistently underestimated flow at high flow rates. Methods to improve accuracy include better accounting for tissue blood volume and minimizing image artifacts.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Gould RGdoi
10.1097/00004424-199212002-00004keywords:
subject
Has Abstractpub_date
1992-12-01 00:00:00pages
S18-21eissn
0020-9996issn
1536-0210journal_volume
27 Suppl 2pub_type
杂志文章,评审abstract::The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197901000-00014
更新日期:1979-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To test noninvasive inductive heating of implanted vascular stents as an alternative approach for reduction or prevention of neointimal hyperplasia. METHODS:Calorimetric pretests were performed to get an orientation on the different parameters of influence for inductive heating of stents. The ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000117881.42422.72
更新日期:2004-05-01 00:00:00
abstract::We measured the amounts of three types of radiographic contrast media (RCM) that could be entrapped in liposomes prepared by the dehydration-rehydration vesicle (DRV) technique. To make DRVs, one initially makes water-containing, small unilamellar vesicles, adds contrast media and lyophilizes the mixture. Upon rehydra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198802000-00009
更新日期:1988-02-01 00:00:00
abstract::Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrat...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198708000-00004
更新日期:1987-08-01 00:00:00
abstract::A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198107000-00007
更新日期:1981-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000077124.24140.bd
更新日期:2003-09-01 00:00:00
abstract::The rate at which isotopes descend from the cisterna magna to the lumbar subarachnoid space is highly variable. In monkeys, with and without previous lumbar puncture, transit time was measured. In animals with a previous lumbar puncture, transit times were 10 to 120 minutes; in monkeys without a previous lumbar punctu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198805000-00005
更新日期:1988-05-01 00:00:00
abstract::We have examined the metabolic behavior of several triiodobenzoic acid derivatives because of the observed mutagenicity and cytotoxicity of 3-amino-5-acetamido-2,4,6-triiodobenzoate (I) and 3,5-diamino-2,4,6-triiodobenzoate (II). Measurements were facilitated using iodine-131 (131I)-labeled compounds. Drug retention i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1981-11-01 00:00:00
abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198908000-00007
更新日期:1989-08-01 00:00:00
abstract::Electromagnetic flow measurement study was performed in 20 anesthetized dogs to evaluate the effect of selective celiac infusion of vasopressin on the hepatic arterial vasculature. Teh hepatic arterial flow showed a biphasic response with an initial decrease followed by a substantial increase in spite of a continued ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1975-05-01 00:00:00
abstract::A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198011001-00053
更新日期:1980-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199507000-00004
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000227
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/magnetic resonance (MR) (with and without diffusion-weighted imaging [DWI]) to F-FDG PET/computed tomography (CT), with regard to the assessment of nodal and extranodal involvement, in patients with Hodgkin lym...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000218
更新日期:2016-03-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199402000-00007
更新日期:1994-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To determine whether vascular endothelial growth factor (VEGF) is a histopathological factor influencing contrast enhancement of hepatocellular carcinoma (HCC) on computed tomography (CT). METHODS:Twenty-two nodular HCCs underwent multiphase helical CT and surgery. Tumor size, histological gra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200108000-00008
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to quantify image quality gains of a moving coronary plaque phantom using dual-source computed tomography (DSCT) providing 83 milliseconds temporal resolution in direct comparison to 64 slice single-source multidetector CT (MDCT) with a temporal resolution of 165 milliseconds. MATE...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000254409.79193.96
更新日期:2007-03-01 00:00:00
abstract::Thoracic metastases from squamous carcinoma and adenocarcinoma of the cervix were studied by reviewing 245 consecutive cases to describe comparative incidence, natural history, and radiographic patterns. The incidence of chest metastases was higher for adenocarcinoma (20%) than for squamous carcinoma (4%). Few patient...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198003000-00004
更新日期:1980-03-01 00:00:00
abstract::At a given radiation dosage and field of view, five variables are under meaningful control for intravenous digital subtraction angiography (IV-DSA): concentration and quantity of contrast media injected, volume of injectate, rate of injection, and site of injection. Some controversy exists regarding the selection of a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198401000-00007
更新日期:1984-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To develop a new animal model for the evaluation of the renal tolerance of contrast agent and its application to diatrizoate and iotrolan injections in comparison to saline and mannitol solution. MATERIALS AND METHODS:The nephrotoxic potential of intravenously injected contrast agents in Beagl...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000087096.61127.13
更新日期:2003-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine to what degree current compressed sensing methods are capable of accelerating clinical magnetic resonance neuroimaging sequences. METHODS:Two 2-dimensional clinical sequences were chosen for this study because of their long scan times. A pilot study was used to establish ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31828a012d
更新日期:2013-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors differentiate breast lesions on sonography by measurements in two compression states that are perpendicular to each other. METHODS:Diameters of 100 breast lesions were measured preoperatively under lateromedial and craniocaudal compression with a new sonographic method. This method...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199607000-00003
更新日期:1996-07-01 00:00:00
abstract::A silicone gel phantom material is described. It can be molded into any shape and it can contain internal cavities. The material is selfsealing allowing the cavities to be filled with liquids. A simple geometric phantom consisting of a rectangular solid with a single internal spherical cavity was fabricated and imaged...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198702000-00013
更新日期:1987-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199711000-00010
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the feasibility of nonenhanced magnetic resonance angiography (MRA) of the lower extremities at 7 tesla (T). MATERIALS AND METHODS:Eight healthy volunteers were examined on a 7-T whole-body magnetic resonance system. For image acquisition, a custom-built 16-channel t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182839c2b
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000431
更新日期:2018-04-01 00:00:00
abstract::Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and di...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198910000-00010
更新日期:1989-10-01 00:00:00
abstract::The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198707000-00004
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate a prototype dual-energy computed tomography calcium subtraction algorithm and its impact on luminal visualization in patients with heavily calcified coronary arteries. MATERIALS AND METHODS:Twenty-nine patients (62% male; mean age, 64 ± 7 years) who had undergone dual-e...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000416
更新日期:2018-02-01 00:00:00
abstract::Magnetic resonance (MR) methods have been used to study the metabolic and vascular response of model tumors to tumor necrosis factor (TNF). Magnetic resonance measurements demonstrated acute reductions in tumor blood flow, measured from tumor uptake of D2O, and in tumor adenosine triphosphate (ATP), measured by 31P ma...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198912000-00022
更新日期:1989-12-01 00:00:00