Evaluation of the dehydration-rehydration method for production of contrast-carrying liposomes.

abstract：OBJECTIVES:The aim of this study was to develop a method to determine hepatic and renal clearance of the 2 diastereoisomers (Gd-A, Gd-B) of Gd-EOB-DTPA separately. MATERIALS AND METHODS:Between July 2017 and February 2018, 41 patients with hepatic disease were prospectively included. For each patient, 1 mL of iopromid...

journal_title：Investigative radiology

authors： Yuan X,Wang S,Shi W,Cai Y,Chen Y,Chen M,Peng Y,Ao G

更新日期：2020-03-01 00:00:00

abstract：:Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...

journal_title：Investigative radiology

authors： Putman CE,Frank JA

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS:Ten pat...

journal_title：Investigative radiology

authors： Freedman JN,Collins DJ,Bainbridge H,Rank CM,Nill S,Kachelrieß M,Oelfke U,Leach MO,Wetscherek A

更新日期：2017-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

journal_title：Investigative radiology

authors： Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVES:Intra-arterial digital subtraction angiography (IA-DSA), an invasive procedure, is the current reference examination after percutaneous transluminal angioplasty and stenting for the detection of in-stent restenosis (ISR). In this phantom study, we evaluated flat-panel angiographic computed tomography after i...

journal_title：Investigative radiology

authors： Psychogios MN,Schramm P,Amelung N,Pilgram-Pastor SM,Gröschel K,Wasser K,Frölich AM,Mohr A,Knauth M

更新日期：2013-02-01 00:00:00

abstract：:Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...

journal_title：Investigative radiology

authors： LeWinter MM,Pavelec RS

更新日期：1982-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:High signal intensity in the basal ganglia on T1-weighted MR imaging has been reported in chronic manganese (Mn) poisoning. However, the exact meaning of the high signal intensity remains unclear: does it result from Mn itself, secondary pathologic changes of the brain tissue, or both? The goal...

journal_title：Investigative radiology

authors： Kim SH,Chang KH,Chi JG,Cheong HK,Kim JY,Kim YM,Han MH

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Though functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examine...

journal_title：Investigative radiology

authors： Barfett JJ,Fierstra J,Mikulis DJ,Krings T

更新日期：2010-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...

journal_title：Investigative radiology

authors： Grimm J,Karger N,Lüsse S,Winoto-Morbach S,Krisch B,Müller-Hülsbeck S,Heller M

更新日期：2000-09-01 00:00:00

abstract：:Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...

journal_title：Investigative radiology

authors： Burbank FH,Thompson WM

更新日期：1986-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The objective of the present study was to compare the data regarding the ability of real-time myocardial contrast echocardiography (MCE) to assess altered myocardial blood flow produced by graded coronary stenoses between open- and closed-chest canine models. MATERIALS AND METHODS:Three grades...

journal_title：Investigative radiology

authors： Masugata H,Peters B,Lafitte S,Yao B,Strachan M,Ling Kwan O,Ohmori K,Mizushige K,Kohno M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:This study aims for targeted biopsy validation of magnetic resonance fingerprinting (MRF) and diffusion mapping for characterizing peripheral zone (PZ) prostate cancer and noncancers. MATERIALS AND METHODS:One hundred four PZ lesions in 85 patients who underwent magnetic resonance imaging were retrospectivel...

journal_title：Investigative radiology

authors： Panda A,OʼConnor G,Lo WC,Jiang Y,Margevicius S,Schluchter M,Ponsky LE,Gulani V

更新日期：2019-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status...

journal_title：Investigative radiology

authors： Link TM,Bauer J,Kollstedt A,Stumpf I,Hudelmaier M,Settles M,Majumdar S,Lochmüller EM,Eckstein F

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the diagnostic value and safety of the contrast agent gadoterate meglumine (Gd-DOTA, DOTAREM, Guerbet, Roissy CdG Cedex, France) in the setting of a postmarketing surveillance study. MATERIALS AND METHODS:Between January 2004 and October 2005, radiologists in 61 radiol...

journal_title：Investigative radiology

authors： Herborn CU,Honold E,Wolf M,Kemper J,Kinner S,Adam G,Barkhausen J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Dynamic contrast-enhanced imaging allows assessing functional information in addition to morphology using various modalities. Several applications have been established in clinical practice; however, there is no standard with respect to injection protocols or postprocessing algorithms. The purpose of this st...

journal_title：Investigative radiology

authors： Brauweiler R,Eisa F,Hupfer M,Nowak T,Kolditz D,Kalender WA

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF) has been related to the use of gadolinium-based contrast agents (GBCAs) in patients undergoing dialysis. The Prospective Fibrose Nephrogénique Systémique study, a French prospective study supported by the French drug regulatory agency (Agence Nationale de Sécurité du Médic...

journal_title：Investigative radiology

authors： Amet S,Launay-Vacher V,Clément O,Frances C,Tricotel A,Stengel B,Gauvrit JY,Grenier N,Reinhardt G,Janus N,Choukroun G,Laville M,Deray G

更新日期：2014-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The capability of an indirect computed tomographic lymphography (CT-LG) using a nonionic monometric contrast medium iopamidol for visualizing breast lymphatic pathways was preliminarily tested. MATERIALS AND METHODS:In 10 female dogs, a total of 0.5 and 1 mL of undiluted iopamidol was injected...

journal_title：Investigative radiology

authors： Suga K,Ogasawara N,Yuan Y,Okada M,Matsunaga N,Tangoku A

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate and validate quantitative susceptibility mapping (QSM) for lesional iron quantification in cerebral cavernous malformations (CCMs). MATERIALS AND METHODS:Magnetic resonance imaging studies were performed in phantoms and 16 patients on a 3-T scanner. Susceptibility ...

journal_title：Investigative radiology

authors： Tan H,Liu T,Wu Y,Thacker J,Shenkar R,Mikati AG,Shi C,Dykstra C,Wang Y,Prasad PV,Edelman RR,Awad IA

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the impact on metal artifacts and dose efficiency of using a tin filter in combination with high-energy threshold (TH) images of a photon-counting detector (PCD) computed tomography (CT) system. MATERIALS AND METHODS:A 3D-printed spine with pedicle screws was scanned...

journal_title：Investigative radiology

authors： Zhou W,Bartlett DJ,Diehn FE,Glazebrook KN,Kotsenas AL,Carter RE,Fletcher JG,McCollough CH,Leng S

更新日期：2019-04-01 00:00:00

abstract：:We have examined the effect of dose on contrast medium-induced reductions in glomerular filtration in anesthetized rabbits. The fraction of renal plasma flow that is filtered, the filtration fraction, was directly measured by the renal arteriovenous difference method using technetium-99m (99mTc) (Sn) DTPA as the trace...

journal_title：Investigative radiology

authors： Harvey LA,Caldicott WJ

更新日期：1983-09-01 00:00:00

abstract：:An ultrasound phantom was constructed simulating fetal femurs in amniotic fluid. Bones of 26, 36, 50, 58, and 70 mm, representative of gestational ages ranging from 17 to 36 weeks, were scanned with mechanical sector, phased sector, and linear array systems (ATL, Diasonics, Acuson, and GE). Measurements were made with...

journal_title：Investigative radiology

authors： Gamba JL,Bowie JD,Dodson WC,Hedlund LW

更新日期：1985-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

journal_title：Investigative radiology

authors： Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

更新日期：2001-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

journal_title：Investigative radiology

authors： Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

更新日期：1993-03-01 00:00:00

abstract：:Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and di...

journal_title：Investigative radiology

authors： Feuerstein IM,Girton ME

更新日期：1989-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate if a quantitative evaluation of a magnetic resonance (MR) perfusion examination of the myocardium can achieve a comparable diagnostic accuracy as a semiquantitative evaluation. METHODS:A total of 31 patients with suspected coronary artery disease underwent MR imaging an...

journal_title：Investigative radiology

authors： Huber A,Sourbron S,Klauss V,Schaefer J,Bauner KU,Schweyer M,Reiser M,Rummeny E,Rieber J

更新日期：2012-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors differentiate acute tubular necrosis from transplant rejection in patients with delayed kidney graft function using gadolinium (Gd)-DTPA enhanced magnetic resonance (MR) imaging. METHODS:Twenty-four patients after renal transplantation (10 with normal graft function, 14 with delaye...

journal_title：Investigative radiology

authors： Preidler KW,Szolar D,Schreyer H,Ebner F,Kern R,Holzer H,Horina JH

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...

journal_title：Investigative radiology

authors： Ni Y,Marchal G,Zhang X,Van Hecke P,Michiels J,Yu J,Rummeny E,Lodemann KP,Baert AL

更新日期：1993-06-01 00:00:00

abstract：PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...

journal_title：Investigative radiology

authors： Bachmann R,Nassenstein I,Kooijman H,Dittrich R,Kugel H,Niederstadt T,Kuhlenbäumer G,Ringelstein EB,Krämer S,Heindel W

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...

journal_title：Investigative radiology

authors： Rempp H,Voigtländer M,Clasen S,Kempf S,Neugebauer A,Schraml C,Schmidt D,Claussen CD,Enderle MD,Goldberg SN,Pereira PL

更新日期：2009-12-01 00:00:00

abstract：:Fractures modeled in the dried skull indicate that the initial plane of computed tomography (CT) section contributes to the accuracy of three-dimensional (3D) images generated from two-dimensional (2D) CT data. The authors retrospectively analyzed seven clinical cases of tripod zygomatic fractures that were imaged wit...

journal_title：Investigative radiology

authors： Levy RA,Kellman RM,Rosenbaum AE

更新日期：1991-05-01 00:00:00