Abstract:
:Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and diatrizoate for DCECT. In this model, diatrizoate made the liver significantly more opaque at four hours than did iopamidol (mean 126.5 vs 87.6 HU, P less than or equal to 0.05). Opacification of the gallbladder and biliary tract occurred more often and was denser with diatrizoate. The relative efficacies of biliary excretion correlate with similarities in molecular structure. While it has been shown that the increased density from DCECT with diatrizoate may allow detection of more metastatic lesions, the clinical utility of the inferior parenchymal density obtained with iopamidol, extrapolated to be approximately 11 to 14 HU in humans, remains to be-established.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Feuerstein IM,Girton MEdoi
10.1097/00004424-198910000-00010subject
Has Abstractpub_date
1989-10-01 00:00:00pages
776-80issue
10eissn
0020-9996issn
1536-0210journal_volume
24pub_type
杂志文章abstract::Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198403000-00007
更新日期:1984-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/01.rli.0000236992.21065.04
更新日期:2006-10-01 00:00:00
abstract::The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Bloo...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198411001-00007
更新日期:1984-11-01 00:00:00
abstract::Ionic (diatrizoate, ioxaglate) and nonionic (iohexol, iosimide, iopromide, and iotrolan) contrast media (CM) were evaluated for their cytogenetic effects in lymphocytes. Heparinized blood was mixed with culture medium RPMI-1640 supplemented with phytohemagglutinin, fetal calf serum, and antibiotics. Plastic tubes cont...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198611000-00006
更新日期:1986-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199508000-00001
更新日期:1995-08-01 00:00:00
abstract::The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197901000-00014
更新日期:1979-01-01 00:00:00
abstract::The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199010000-00007
更新日期:1990-10-01 00:00:00
abstract:UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-200103000-00005
更新日期:2001-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Density of trabecular bone structures in human heel bones was assessed by 3D magnetic resonance (MR) gradient echo imaging (GEI) with multiple echoes. Different spatial resolutions were applied to investigate the influence of the pixel size on signal characteristics in GEI and to find suitable ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200007000-00001
更新日期:2000-07-01 00:00:00
abstract::The feasibility of control of traumatic hepatic hemorrhage by angiographic transcatheter embolization was investigated. Bleeding sites were created in the livers of each of twelve dogs, and the hepatic artery was occluded with Gelfoam. Successful control of bleeding was demonstrated by postembolization angiography in ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197801000-00014
更新日期:1978-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199903000-00014
更新日期:1999-03-01 00:00:00
abstract::There are a number of sonographic findings seen in fibroadenoma of the breast. In a retrospective study, we examined the biopsy results of 59 masses given the sonographic diagnosis of fibroadenoma. We also reviewed the sonograms of an additional 26 biopsy-proven fibroadenomas that were not diagnosed as such with ultra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198601000-00006
更新日期:1986-01-01 00:00:00
abstract::Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/00004424-199911000-00004
更新日期:1999-11-01 00:00:00
abstract::The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199102000-00017
更新日期:1991-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199706000-00006
更新日期:1997-06-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199402000-00007
更新日期:1994-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the changes in the microbubble population of a currently available ultrasound contrast agent (USCA) through attenuation measurements to optimize its clinical use. MATERIALS AND METHODS:The microbubble population from a galactose-based USCA (Levovist, Schering AG, Germany) was chara...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200212000-00006
更新日期:2002-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000116125.96544.64
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:We sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (MI) in cardiac multislice spiral computed tomography (MSCT). MATERIALS AND METHODS:Acute MI was induced in 12 domestic pigs by a 45-minute balloon occlusion of the left anterior descending artery. Delayed...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000251577.68223.84
更新日期:2007-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000055289.97726.B1
更新日期:2003-03-01 00:00:00
abstract:INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000067491.31978.1c
更新日期:2003-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199506000-00008
更新日期:1995-06-01 00:00:00
abstract::The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198211000-00007
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000131
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318243e062
更新日期:2012-05-01 00:00:00
abstract::The authors present a numerical deconvolution technique to compensate for image degrading effects caused by scattered photons in radiographic chest images. Fourier transform techniques are used to deconvolve a shift invariant model of the two dimensional point spread response functions of the scattered radiation. This...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198901000-00008
更新日期:1989-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of the study was to evaluate the effect of articular fluid distention on patellar position at different degrees of knee angulation. METHODS:Patellar position in 10 cadaveric knee specimens was determined with 30, 100, and 200 mm Hg joint distention at 45, 20, and 5 degrees of knee ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199602000-00001
更新日期:1996-02-01 00:00:00
abstract::Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198603000-00009
更新日期:1986-03-01 00:00:00
abstract:PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31827b711e
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the influence of different weighting factors on contrast enhancement, signal-to-noise ratio (SNR), and image quality in image fusion in dual energy computed tomography (DECT) angiography. MATERIAL AND METHODS:Fifteen patients underwent a CT angiography of the aorta with ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31818c3d4b
更新日期:2009-01-01 00:00:00