Choice of contrast material for four-hour delayed contrast-enhanced computed tomography of the liver.

Abstract:

:Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and diatrizoate for DCECT. In this model, diatrizoate made the liver significantly more opaque at four hours than did iopamidol (mean 126.5 vs 87.6 HU, P less than or equal to 0.05). Opacification of the gallbladder and biliary tract occurred more often and was denser with diatrizoate. The relative efficacies of biliary excretion correlate with similarities in molecular structure. While it has been shown that the increased density from DCECT with diatrizoate may allow detection of more metastatic lesions, the clinical utility of the inferior parenchymal density obtained with iopamidol, extrapolated to be approximately 11 to 14 HU in humans, remains to be-established.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Feuerstein IM,Girton ME

doi

10.1097/00004424-198910000-00010

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

776-80

issue

10

eissn

0020-9996

issn

1536-0210

journal_volume

24

pub_type

杂志文章
  • Increased urine histamine and contrast media reactions.

    abstract::Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198403000-00007

    authors: Kaliner M,Dyer J,Merlin S,Shelton A,Greenhill A,Treadwell G,McKenna W,Lieberman P

    更新日期:1984-03-01 00:00:00

  • Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: initial results using highly accelerated parallel acquisition.

    abstract:OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.rli.0000236992.21065.04

    authors: Nael K,Fenchel M,Salamon N,Duckwiler GR,Laub G,Finn JP,Villablanca JP

    更新日期:2006-10-01 00:00:00

  • Relative uptake of low- and high-osmolality contrast media in CT of brain tumors.

    abstract::The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Bloo...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198411001-00007

    authors: Fike JR,Cann CE,Norman D,Turrel JM,LeCouteur RA,Pflugfeld CM,Borcich JK

    更新日期:1984-11-01 00:00:00

  • Contrast media-induced chromosomal damage in human lymphocyte cultures.

    abstract::Ionic (diatrizoate, ioxaglate) and nonionic (iohexol, iosimide, iopromide, and iotrolan) contrast media (CM) were evaluated for their cytogenetic effects in lymphocytes. Heparinized blood was mixed with culture medium RPMI-1640 supplemented with phytohemagglutinin, fetal calf serum, and antibiotics. Plastic tubes cont...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198611000-00006

    authors: Parvez Z,Kormano M,Moncada R,Eklund R

    更新日期:1986-11-01 00:00:00

  • BR1: a new ultrasonographic contrast agent based on sulfur hexafluoride-filled microbubbles.

    abstract:RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199508000-00001

    authors: Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

    更新日期:1995-08-01 00:00:00

  • Comparative cranial CT enhancement in the normal primate.

    abstract::The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197901000-00014

    authors: Drayer BP,Wolfson SK Jr,Rosenbaum AE,Dujovny M,Boehnke M,Cook EE

    更新日期:1979-01-01 00:00:00

  • Detection of breast abnormalities on teleradiology transmitted mammograms.

    abstract::The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199010000-00007

    authors: Fajardo LL,Yoshino MT,Seeley GW,Hunt R,Hunter TB,Friedman R,Cardenas D,Boyle R

    更新日期:1990-10-01 00:00:00

  • Evaluation of CT time-density curves of lower-limb veins.

    abstract:UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004424-200103000-00005

    authors: Szapiro D,Ghaye B,Willems V,Zhang L,Albert A,Dondelinger RF

    更新日期:2001-03-01 00:00:00

  • Magnetic resonance osteodensitometry in human heel bones: correlation with quantitative computed tomography using different measuring parameters.

    abstract:RATIONALE AND OBJECTIVES:Density of trabecular bone structures in human heel bones was assessed by 3D magnetic resonance (MR) gradient echo imaging (GEI) with multiple echoes. Different spatial resolutions were applied to investigate the influence of the pixel size on signal characteristics in GEI and to find suitable ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200007000-00001

    authors: Machann J,Schnatterbeck P,Raible A,Lutz O,Claussen CD,Schick F

    更新日期:2000-07-01 00:00:00

  • Control of experimental traumatic hepatic hemorrhage by transcatheter embolization.

    abstract::The feasibility of control of traumatic hepatic hemorrhage by angiographic transcatheter embolization was investigated. Bleeding sites were created in the livers of each of twelve dogs, and the hepatic artery was occluded with Gelfoam. Successful control of bleeding was demonstrated by postembolization angiography in ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197801000-00014

    authors: Tyler T,Rosenbaum HD

    更新日期:1978-01-01 00:00:00

  • MRI dosimetry: a fast quantitative MRI method to determine 3D absorbed dose distributions.

    abstract:RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199903000-00014

    authors: Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

    更新日期:1999-03-01 00:00:00

  • The spectrum of sonographic findings of fibroadenoma of the breast.

    abstract::There are a number of sonographic findings seen in fibroadenoma of the breast. In a retrospective study, we examined the biopsy results of 59 masses given the sonographic diagnosis of fibroadenoma. We also reviewed the sonograms of an additional 26 biopsy-proven fibroadenomas that were not diagnosed as such with ultra...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198601000-00006

    authors: Jackson VP,Rothschild PA,Kreipke DL,Mail JT,Holden RW

    更新日期:1986-01-01 00:00:00

  • Pathophysiology of radiocontrast nephropathy: a role for medullary hypoxia.

    abstract::Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-199911000-00004

    authors: Heyman SN,Reichman J,Brezis M

    更新日期:1999-11-01 00:00:00

  • Hardcopy recording technologies for digitally formatted image data.

    abstract::The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199102000-00017

    authors: Siegel EL,Bishop MD,Wetzel LH,Anderson WF,McMillan JH

    更新日期:1991-02-01 00:00:00

  • Lung perfusion demonstrated by contrast-enhanced dynamic magnetic resonance imaging. Application to unilateral lung transplantation.

    abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199706000-00006

    authors: Berthezène Y,Croisille P,Bertocchi M,Houzard C,Bendib K,Revel D

    更新日期:1997-06-01 00:00:00

  • Tubal sterilization by selective catheterization in an animal model.

    abstract:RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199402000-00007

    authors: Maubon A,Rouanet JP,Laurent A,Joujoux JM,Cover S,Courtieu C,Wassef M,Godlewski G,Honiger J,Lopez FM

    更新日期:1994-02-01 00:00:00

  • Optimizing an ultrasound contrast agent's stability using in vitro attenuation measurements.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the changes in the microbubble population of a currently available ultrasound contrast agent (USCA) through attenuation measurements to optimize its clinical use. MATERIALS AND METHODS:The microbubble population from a galactose-based USCA (Levovist, Schering AG, Germany) was chara...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200212000-00006

    authors: Correas JM,Kurtisovski E,Bridal SL,Amararene A,Hélénon O,Berger G

    更新日期:2002-12-01 00:00:00

  • Inhibition of restenosis in stented porcine coronary arteries: uptake of Paclitaxel from angiographic contrast media.

    abstract:RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000116125.96544.64

    authors: Speck U,Scheller B,Abramjuk C,Grossmann S,Mahnkopf D,Simon O

    更新日期:2004-03-01 00:00:00

  • Low tube voltage improves computed tomography imaging of delayed myocardial contrast enhancement in an experimental acute myocardial infarction model.

    abstract:OBJECTIVE:We sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (MI) in cardiac multislice spiral computed tomography (MSCT). MATERIALS AND METHODS:Acute MI was induced in 12 domestic pigs by a 45-minute balloon occlusion of the left anterior descending artery. Delayed...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000251577.68223.84

    authors: Mahnken AH,Bruners P,Mühlenbruch G,Emmerich M,Hohl C,Günther RW,Wildberger JE

    更新日期:2007-02-01 00:00:00

  • Sensitivity to detect small coronary artery calcium lesions with varying slice thickness using electron beam tomography.

    abstract:RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.RLI.0000055289.97726.B1

    authors: Mao S,Child J,Carson S,Liu SC,Oudiz RJ,Budoff MJ

    更新日期:2003-03-01 00:00:00

  • High-resolution magnetic resonance imaging at 2 Tesla: potential for atherosclerotic lesions exploration in the apolipoprotein E knockout mouse.

    abstract:INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000067491.31978.1c

    authors: Chaabane L,Soulas EC,Contard F,Salah A,Guerrier D,Briguet A,Douek P

    更新日期:2003-08-01 00:00:00

  • Biodistribution of radiolabeled, formulated gadopentetate, gadoteridol, gadoterate, and gadodiamide in mice and rats.

    abstract:RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199506000-00008

    authors: Tweedle MF,Wedeking P,Kumar K

    更新日期:1995-06-01 00:00:00

  • Timing and magnitude of the postural effect on the distribution of pulmonary blood flow.

    abstract::The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198211000-00007

    authors: Kuribayashi S,Garnic JD,Abrams HL

    更新日期:1982-11-01 00:00:00

  • Segmentation-based attenuation correction in positron emission tomography/magnetic resonance: erroneous tissue identification and its impact on positron emission tomography interpretation.

    abstract:OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000131

    authors: Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

    更新日期:2015-05-01 00:00:00

  • Value of in vivo T2 measurement for myocardial fibrosis assessment in diabetic mice at 11.75 T.

    abstract:OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e318243e062

    authors: Bun SS,Kober F,Jacquier A,Espinosa L,Kalifa J,Bonzi MF,Kopp F,Lalevee N,Zaffran S,Deharo JC,Cozzone PJ,Bernard M

    更新日期:2012-05-01 00:00:00

  • Scatter compensation in digital chest radiography using Fourier deconvolution.

    abstract::The authors present a numerical deconvolution technique to compensate for image degrading effects caused by scattered photons in radiographic chest images. Fourier transform techniques are used to deconvolve a shift invariant model of the two dimensional point spread response functions of the scattered radiation. This...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198901000-00008

    authors: Floyd CE,Beatty PT,Ravin CE

    更新日期:1989-01-01 00:00:00

  • Effect of intraarticular pressure on patellar position. Computed tomography study in cadaveric specimens.

    abstract:RATIONALE AND OBJECTIVES:The purpose of the study was to evaluate the effect of articular fluid distention on patellar position at different degrees of knee angulation. METHODS:Patellar position in 10 cadaveric knee specimens was determined with 30, 100, and 200 mm Hg joint distention at 45, 20, and 5 degrees of knee ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199602000-00001

    authors: Brossmann J,Koch S,Schwarzenberg H,Link J,Muhle C,Bull CC,Heller M

    更新日期:1996-02-01 00:00:00

  • Contrast media tonicity. Part I. Effects upon IV-DSA time-concentration curve peak and width: experimental studies.

    abstract::Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198603000-00009

    authors: Burbank FH,Thompson WM

    更新日期:1986-03-01 00:00:00

  • Evaluation of diffusion-weighted MR imaging at inclusion in an active surveillance protocol for low-risk prostate cancer.

    abstract:PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31827b711e

    authors: Somford DM,Hoeks CM,Hulsbergen-van de Kaa CA,Hambrock T,Fütterer JJ,Witjes JA,Bangma CH,Vergunst H,Smits GA,Oddens JR,van Oort IM,Barentsz JO,MR-PRIAS Collaboration Group.

    更新日期:2013-03-01 00:00:00

  • Image fusion in dual energy computed tomography: effect on contrast enhancement, signal-to-noise ratio and image quality in computed tomography angiography.

    abstract:OBJECTIVE:The aim of this study was to evaluate the influence of different weighting factors on contrast enhancement, signal-to-noise ratio (SNR), and image quality in image fusion in dual energy computed tomography (DECT) angiography. MATERIAL AND METHODS:Fifteen patients underwent a CT angiography of the aorta with ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31818c3d4b

    authors: Behrendt FF,Schmidt B,Plumhans C,Keil S,Woodruff SG,Ackermann D,Mühlenbruch G,Flohr T,Günther RW,Mahnken AH

    更新日期:2009-01-01 00:00:00