Value of in vivo T2 measurement for myocardial fibrosis assessment in diabetic mice at 11.75 T.

abstract：RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...

journal_title：Investigative radiology

authors： Grimm J,Karger N,Lüsse S,Winoto-Morbach S,Krisch B,Müller-Hülsbeck S,Heller M

更新日期：2000-09-01 00:00:00

abstract：:The feasibility of control of traumatic hepatic hemorrhage by angiographic transcatheter embolization was investigated. Bleeding sites were created in the livers of each of twelve dogs, and the hepatic artery was occluded with Gelfoam. Successful control of bleeding was demonstrated by postembolization angiography in ...

journal_title：Investigative radiology

authors： Tyler T,Rosenbaum HD

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the influence of different weighting factors on contrast enhancement, signal-to-noise ratio (SNR), and image quality in image fusion in dual energy computed tomography (DECT) angiography. MATERIAL AND METHODS:Fifteen patients underwent a CT angiography of the aorta with ...

journal_title：Investigative radiology

authors： Behrendt FF,Schmidt B,Plumhans C,Keil S,Woodruff SG,Ackermann D,Mühlenbruch G,Flohr T,Günther RW,Mahnken AH

更新日期：2009-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the abilities of dynamic diffusion-weighted MRI to demonstrate the effects in vivo of a high-viscosity iodinated contrast agent on medullary and cortical blood flow in the rat kidney. METHODS:Dynamic diffusion-weighted, echoplanar MR images obtained from five b-value single-shot acqu...

journal_title：Investigative radiology

authors： Laissy JP,Menegazzo D,Dumont E,Piekarski JD,Karila-Cohen P,Chillon S,Schouman-Claeys E

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the value of intravoxel incoherent motion and diffusion-weighted imaging for predicting the histologic grade of pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:Forty patients with surgically diagnosed PNETs who underwent preoperative magnetic resonance im...

journal_title：Investigative radiology

authors： Hwang EJ,Lee JM,Yoon JH,Kim JH,Han JK,Choi BI,Lee KB,Jang JY,Kim SW,Nickel MD,Kiefer B

更新日期：2014-06-01 00:00:00

abstract：:Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia, imbalance between oxyge...

journal_title：Investigative radiology

authors： Heyman SN,Reichman J,Brezis M

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to elucidate the mechanism of hepatic parenchyma-specific contrast of Sonazoid (microbubble contrast agent) using microscopic techniques. MATERIALS AND METHODS:Sonazoid was intravenously injected into rats to investigate the microbubble dynamics and distribution within hepatic...

journal_title：Investigative radiology

authors： Watanabe R,Matsumura M,Munemasa T,Fujimaki M,Suematsu M

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the feasibility of the combination of magnetic resonance (MR)-guided biopsy (MRGB) and diagnostic 3T MR imaging in the localization of local recurrence of prostate cancer (PCa) after external beam radiation therapy (EBRT). MATERIALS AND METHODS:Twenty-four consecuti...

journal_title：Investigative radiology

authors： Yakar D,Hambrock T,Huisman H,Hulsbergen-van de Kaa CA,van Lin E,Vergunst H,Hoeks CM,van Oort IM,Witjes JA,Barentsz JO,Fütterer JJ

更新日期：2010-03-01 00:00:00

abstract：:Pyrroxamide [N-(1-hydroxymethyl-2,3-dihydroxypropyl)-2,2,5,5-tetramethyl pyrrolidine-1-oxyl-3-carboxyamide] is a newly tested nonionic monomeric nitroxyl compound with demonstrated effectiveness for MRI contrast enhancement at doses as low as 10(-3) M. Pyrroxamide and its hydroxylamine metabolic derivative were tested...

journal_title：Investigative radiology

authors： Gordon DG,Brasch RC,Ogan MD,Deen D

更新日期：1988-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...

journal_title：Investigative radiology

authors： Pfirrmann CW,Huser M,Székely G,Hodler J,Gerber C

更新日期：2002-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether gadolinium-ethoxybenzyl-DTPA (Gd-EOB-DTPA) can be eliminated in the absence of the two usual excretory pathways (urinary or biliary) and whether a remaining excretory pathway is able to compensate for impaired liver or kidney function. METHODS:The study was per...

journal_title：Investigative radiology

authors： Mühler A,Heinzelmann I,Weinmann HJ

更新日期：1994-02-01 00:00:00

abstract：:Observer performance in radiologic interpretation has traditionally been based upon Receiver Operating Characteristic (ROC) analysis. A statistical method that evaluates the reproducibility or consistency of radiologic interpretation is presented. Since this method is not based upon pathologic verification, it cannot ...

journal_title：Investigative radiology

authors： Herman S,DeBoer G,Rideout DF,Majesky IF

更新日期：1984-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00

abstract：:Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...

journal_title：Investigative radiology

authors： Dae M,Canhasi B,Botvinick E,Olvera S,Schechtmann N,Engelstad B,Hattner R,Schiller N,O'Connell W,Faulkner D

更新日期：1985-07-01 00:00:00

abstract：:Three facets of dual-energy quantitative computed tomography are studied: (1) the algorithm for postprocessing data (the methods of Cann, Laval-Jeantet et al, Goodsitt et al [two methods], and Nickoloff et al); (2) the influence of choice of tissue-equivalent materials for calibration; and (3) the difference between c...

journal_title：Investigative radiology

authors： van Kuijk C,Grashuis JL,Steenbeek JC,Schütte HE,Trouerbach WT

更新日期：1990-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Ureteric jet index (UJI), a newly developed technique derived from color Doppler ultrasonography, may hold promise in evaluating renal function because of its ability to evaluate individual renal function and the use of nonionizing radiation. To assess the usefulness of UJI, the authors in this...

journal_title：Investigative radiology

authors： Chiu NT,Wu CC,Yao WJ,Tu DG,Lee BF,Tong YC,Pan CC

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...

journal_title：Investigative radiology

authors： Diekmann F,Diekmann S,Jeunehomme F,Muller S,Hamm B,Bick U

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

journal_title：Investigative radiology

authors： Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

更新日期：2015-03-01 00:00:00

abstract：:The problem of inhomogeneous mixing encountered during hepatic artery (HA) chemotherapy infusion was assessed and a practical solution examined. A glass model of the human HA distribution was used to determine mixing homogeneity of low flow (1.4 mL/minute) dye infusion into pulsatile flow (280-300 mL/minute) of a flui...

journal_title：Investigative radiology

authors： Barth KH,Lutz RJ,Kremers PW,Miller DL

更新日期：1988-07-01 00:00:00

abstract：:Radiolabeled blood cells are widely used for both clinical and research studies. In vitro and in vivo studies have shown the tagging process does not significantly affect function. The labeling techniques and clinical uses of labeled leukocytes and platelets are reviewed. ...

journal_title：Investigative radiology

authors： Datz FL

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to assess the feasibility of magnetic resonance cholangiography (MRC) using biliary-secreted gadoxetic acid at 7 T and to compare it with T2-weighted (w) MRC at 3 T. MATERIALS AND METHODS:Ten healthy volunteers were examined on a 7-T whole-body magnetic resonance system. T2...

journal_title：Investigative radiology

authors： Fischer A,Kraff O,Orzada S,Nensa F,Schäfer LC,Ladd ME,Umutlu L,Lauenstein TC

更新日期：2014-05-01 00:00:00

abstract：:We investigated the feasibility of using intravascular ultrasound imaging to analyze vascular physiology in various arterial beds. Canine superficial femoral, external iliac, and common carotid arteries were harvested and suspended and perfused in a bath of oxygenated, heated, physiologic salt solution. A 6-Fr, 20-MHz...

journal_title：Investigative radiology

authors： Wilson MW,Webb RC,Marx MV,Meyer CR,Gallagher MA,Haarer SL,Buda AJ,Williams DM

更新日期：1991-03-01 00:00:00

abstract：:The potential risk of a radiologic procedure often is compared with the potential benefit of the procedure. While risk vs. benefit analysis has been useful as a step toward increased communication and understanding among radiologists, referring physicians, and the general public, it has the disadvantage that risk and ...

journal_title：Investigative radiology

authors： Ritenour ER,Hendee WR

更新日期：1989-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The objective of the present study was to compare the data regarding the ability of real-time myocardial contrast echocardiography (MCE) to assess altered myocardial blood flow produced by graded coronary stenoses between open- and closed-chest canine models. MATERIALS AND METHODS:Three grades...

journal_title：Investigative radiology

authors： Masugata H,Peters B,Lafitte S,Yao B,Strachan M,Ling Kwan O,Ohmori K,Mizushige K,Kohno M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

journal_title：Investigative radiology

authors： Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the magnetic resonance prostate imaging reporting and data system (PI-RADS) for the detection of prostate cancer by the results of magnetic resonance imaging (MRI)-guided biopsy of the prostate as a reference standard. PATIENTS AND METHODS:In 55 patients who had underg...

journal_title：Investigative radiology

authors： Baur AD,Maxeiner A,Franiel T,Kilic E,Huppertz A,Schwenke C,Hamm B,Durmus T

更新日期：2014-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

journal_title：Investigative radiology

authors： Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

更新日期：1997-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

journal_title：Investigative radiology

authors： Tweedle MF,Wedeking P,Kumar K

更新日期：1995-06-01 00:00:00

abstract：:The microangiographic anatomy of the cat's eye is presented. The characteristic vascular pattern of each of the three distinct circulations, retinal choroidal, and ciliary is described and illustrated. ...

journal_title：Investigative radiology

authors： Rothman SL,Kier EL,Deuker DK

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...

journal_title：Investigative radiology

authors： Ladwig M,Flemming B,Seeliger E,Sargsyan L,Persson PB

更新日期：2011-11-01 00:00:00