Abstract:
OBJECTIVES:The objective of this study was to assess the feasibility of the combination of magnetic resonance (MR)-guided biopsy (MRGB) and diagnostic 3T MR imaging in the localization of local recurrence of prostate cancer (PCa) after external beam radiation therapy (EBRT). MATERIALS AND METHODS:Twenty-four consecutive men with biochemical failure suspected of local recurrence after initial EBRT were enrolled prospectively in this study. All patients underwent a diagnostic 3T MR examination of the prostate. T2-weighted and dynamic contrast-enhanced MR images (DCE-MRI) were acquired. Two radiologists evaluated the MR images in consensus for tumor suspicious regions (TSRs) for local recurrence. Subsequently, these TSRs were biopsied under MR-guidance and histopathologically evaluated for the presence of recurrent PCa. Descriptive statistical analysis was applied. RESULTS:Tissue sampling was successful in all patients and all TSRs. The positive predictive value on a per patient basis was 75% (15/20) and on a per TSR basis 68% (26/38). The median number of biopsies taken per patient was 3, and the duration of an MRGB session was 31 minutes. No intervention-related complications occurred. CONCLUSIONS:The combination of MRGB and diagnostic MR imaging of the prostate was a feasible technique to localize PCa recurrence after EBRT using a low number of cores in a clinically acceptable time.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Yakar D,Hambrock T,Huisman H,Hulsbergen-van de Kaa CA,van Lin E,Vergunst H,Hoeks CM,van Oort IM,Witjes JA,Barentsz JO,Fütterer JJdoi
10.1097/RLI.0b013e3181c7bcdasubject
Has Abstractpub_date
2010-03-01 00:00:00pages
121-5issue
3eissn
0020-9996issn
1536-0210journal_volume
45pub_type
杂志文章abstract::Frequency spectral analysis of cardiac wall motion as calculated from the recorded video kymogram are demonstrated. Characteristic harmonics following the fundamental frequency of the cardiac rate have been demonstrated to have an alternating sequential energy distribution as measured from the free margin of the left ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197503000-00005
更新日期:1975-03-01 00:00:00
abstract:OBJECTIVE:With the introduction of ultrashort echo time (UTE) sequences solid polymeric materials might become visible on clinical whole-body magnetic resonance (MR) scanners. The aim of this study was to characterize solid polymeric materials typically used for instruments in magnetic resonance guided interventions an...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318188601f
更新日期:2008-11-01 00:00:00
abstract::Receiver operating characteristic (ROC) analysis has been used in a broad variety of medical imaging studies during the past 15 years, and its advantages over more traditional measures of diagnostic performance are now clearly established. But despite the essential simplicity of the approach, workers in the field ofte...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198903000-00012
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b66d11
更新日期:2009-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199509000-00004
更新日期:1995-09-01 00:00:00
abstract::Effectiveness of terbutaline, a potent uterine muscle relaxant, for differentiation of temporary and anatomic interstitial fallopian tube obstruction (IFTO) at hysterosalpingography (HSG) was explored. In 43 IFTO evaluated, HSG after terbutaline showed patency in only one of 16 tubes in which IFTO was caused by spasm ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198803000-00010
更新日期:1988-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To determine whether vascular endothelial growth factor (VEGF) is a histopathological factor influencing contrast enhancement of hepatocellular carcinoma (HCC) on computed tomography (CT). METHODS:Twenty-two nodular HCCs underwent multiphase helical CT and surgery. Tumor size, histological gra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200108000-00008
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000431
更新日期:2018-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199510000-00006
更新日期:1995-10-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199009000-00010
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the potential of iterative metal artifact reduction (IMAR) for the improvement of computed tomography (CT)-based position emission tomography (PET) attenuation correction in the vicinity of metal implants and compare it with dual-energy-based metal artifact reduction stra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000306
更新日期:2017-01-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199110000-00009
更新日期:1991-10-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31819b00f1
更新日期:2009-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Our purpose was to validate contrast-enhanced computed tomography (CECT)-derived quantitative measures of perfusion and permeability against gold standard techniques of fluorescent microspheres and Evan's Blue dye, respectively. MATERIALS AND METHODS:Normal and tumor-bearing (R3230AC) Fischer ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01rli.0000124456.82985.35
更新日期:2004-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Ureteric jet index (UJI), a newly developed technique derived from color Doppler ultrasonography, may hold promise in evaluating renal function because of its ability to evaluate individual renal function and the use of nonionizing radiation. To assess the usefulness of UJI, the authors in this...
journal_title:Investigative radiology
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doi:10.1097/00004424-199908000-00001
更新日期:1999-08-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199301000-00032
更新日期:1993-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199704000-00008
更新日期:1997-04-01 00:00:00
abstract::A 144cerium-induced osteosarcoma was transplanted to athymic nude rats (Han:rnu/rnu). Nineteen of the tumor-bearing animals were used to demonstrate the characteristics of the osteosarcoma on magnetic resonance imaging (MRI) in comparison with a group of nine animals that had not received any tumor transplant. The tum...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
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journal_title:Investigative radiology
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doi:10.1097/RLI.0b013e31824f54cb
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199804000-00008
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doi:10.1097/00004424-199909000-00002
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journal_title:Investigative radiology
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000195836.57778.1f
更新日期:2006-02-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199508000-00001
更新日期:1995-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199401000-00012
更新日期:1994-01-01 00:00:00
abstract::Using cardiac-gated fast acquisition with multiple excitation (FAME), time curves of the cerebral aqueduct signals were derived in 19 healthy volunteers and 14 patients. A mean curve of the normal subjects was determined during systole. A relatively stable point of time was found at 270 msec after the R-wave supposed ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198911000-00004
更新日期:1989-11-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
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更新日期:2006-04-01 00:00:00
abstract::Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199304001-00014
更新日期:1993-04-01 00:00:00
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journal_title:Investigative radiology
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更新日期:2007-06-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
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更新日期:1993-10-01 00:00:00