Right-Angled Traction Bronchiectasis in Differentiating Idiopathic Pulmonary Fibrosis Without Honeycombing From Idiopathic Nonspecific Interstitial Pneumonia.


OBJECTIVES:The aim of this study was to conduct a radiopathologic evaluation of right-angled traction bronchiectasis to differentiate idiopathic pulmonary fibrosis (IPF) without honeycombing from idiopathic nonspecific interstitial pneumonia (NSIP). MATERIALS AND METHODS:The derivation cohort included 78 consecutive patients with idiopathic NSIP (n = 39) or IPF (n = 39) without honeycombing who underwent preoperative thin-section computed tomography scans at a single tertiary hospital. The validation cohort comprised 22 patients (14 IPF and 8 NSIP) from another institution. We assessed conventional computed tomography findings, right-angled traction bronchiectasis on minimum intensity projection (MinIP) images, and pathologic features associated with right-angled bronchiectasis. Right-angled traction bronchiectasis was defined as abrupt kinking of a single bronchus by over 90 degrees or an abrupt angle close to 180 degrees of branching bronchi in the background of fibrosis. In the validation cohort, we evaluated the proportion of correct IPF diagnoses and interobserver agreement of 4 radiologists before and after reviewing MinIP images. RESULTS:A probable usual interstitial pneumonia (UIP) pattern (odds ratio [OR], 6.948; 95% confidence interval [CI], 1.525-31.654; P = 0.012) and right-angled traction bronchiectasis (OR, 6.004; 95% CI, 1.980-18.209; P = 0.002) were independently associated with IPF. Patients with right-angled traction bronchiectasis were more likely to have extensive reticular opacity (OR, 1.149; 95% CI, 1.077-1.225; P < 0.001) and pathologically were more likely to have a broad extent of subpleural fibrosis (OR, 4.000; 95% CI, 1.457-10.987; P = 0.007) and relatively thick fibrosis (OR, 7.750; 95% CI, 2.504-23.991; P < 0.001). After reviewing MinIP images, the proportion of correct diagnoses increased from 40.9% to 54.5% to 50.0% to 77.3%. The mean kappa value for right-angled traction bronchiectasis was 0.489 ± 0.192. CONCLUSIONS:Right-angled traction bronchiectasis pathologically reflected a subpleural predominance of fibrosis and partly supported the radiologic differentiation of IPF without honeycombing from idiopathic NSIP.


Invest Radiol


Investigative radiology


Kim H,Yoon SH,Lee HJ,Song SG,Koh J,Jeon YK,Chae KJ,Jin GY,Jin KN,Lee KY,Goo JM




Has Abstract


2020-06-01 00:00:00












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    authors: Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

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    authors: Gómez M,Aguado F,Manuel J,Menéndez JM,Revilla M,Villa LF,Cortés J,Rico H

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  • Facilitated Diagnosis of Pneumothoraces in Newborn Mice Using X-ray Dark-Field Radiography.

    abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...

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    authors: Hellbach K,Yaroshenko A,Willer K,Pritzke T,Baumann A,Hesse N,Auweter S,Reiser MF,Eickelberg O,Pfeiffer F,Hilgendorff A,Meinel FG

    更新日期:2016-10-01 00:00:00

  • MRI dosimetry: a fast quantitative MRI method to determine 3D absorbed dose distributions.

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    authors: Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

    更新日期:1999-03-01 00:00:00

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    authors: Inoue E,Kuroda C,Narumi Y,Fujita M,Kadota T,Kuriyama K,Yoshioka H,Ishiguro S,Sasaki Y,Imaoka S

    更新日期:1993-08-01 00:00:00

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    authors: Ropers D,Regenfus M,Stilianakis N,Birke S,Kessler W,Moshage W,Laub G,Daniel WG,Achenbach S

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    更新日期:2003-06-01 00:00:00