Radiolabeled leukocytes and platelets.

Abstract:

:Radiolabeled blood cells are widely used for both clinical and research studies. In vitro and in vivo studies have shown the tagging process does not significantly affect function. The labeling techniques and clinical uses of labeled leukocytes and platelets are reviewed.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Datz FL

doi

10.1097/00004424-198603000-00001

subject

Has Abstract

pub_date

1986-03-01 00:00:00

pages

191-200

issue

3

eissn

0020-9996

issn

1536-0210

journal_volume

21

pub_type

杂志文章,评审
  • In vivo and in vitro evaluation of Gd-DTPA-polylysine as a macromolecular contrast agent for magnetic resonance imaging.

    abstract::Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199111000-00008

    authors: Schuhmann-Giampieri G,Schmitt-Willich H,Frenzel T,Press WR,Weinmann HJ

    更新日期:1991-11-01 00:00:00

  • Evaluation of radiologist interpretive performance using blinded reads by multiple external readers.

    abstract:OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181d2ee97

    authors: Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

    更新日期:2010-04-01 00:00:00

  • Increased ablation zones using a cryo-based internally cooled bipolar RF applicator in ex vivo bovine liver.

    abstract:PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181b66d11

    authors: Rempp H,Voigtländer M,Clasen S,Kempf S,Neugebauer A,Schraml C,Schmidt D,Claussen CD,Enderle MD,Goldberg SN,Pereira PL

    更新日期:2009-12-01 00:00:00

  • Searching for lung nodules. Visual dwell indicates locations of false-positive and false-negative decisions.

    abstract::Eye position recordings made while radiologists searched chest images for lung nodules showed that regions falsely reported positive or suspicious received prolonged visual attention. Correlation of regional fixation dwell time with independent ratings of image features indicated that more than 90% of false-positive d...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:

    authors: Kundel HL,Nodine CF,Krupinski EA

    更新日期:1989-06-01 00:00:00

  • Clinical experience with saralasin infusion in hypertensive patients.

    abstract::Renal arteriography gives a reliable anatomic delineation of the renal vasculature. However, the presence of renal arterial disease does not determine the physiologic significance of the lesion. The intravenous infusion of saralasin, a specific angiotensin II antagonist, has been investigated as a method for identify...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197711000-00006

    authors: Tegtmeyer CJ,Latour EA,Vaughan ED Jr,Ayers CR,Carey RM,Wellons HA Jr

    更新日期:1977-11-01 00:00:00

  • Ultrasound bone velocity on proximal phalanges in premenopausal, perimenopausal, and postmenopausal healthy women.

    abstract:RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199701000-00011

    authors: Aguado F,Revilla M,Hernández ER,Villa LF,Rico H

    更新日期:1997-01-01 00:00:00

  • Direct video-microscopic observation of the dynamic effects of medical ultrasound on ultrasound contrast microspheres.

    abstract:RATIONALE AND OBJECTIVES:Ultrasound can cause destruction of microbubble contrast agents used to enhance medical ultrasound imaging. This study sought to characterize the dynamics of this interaction by direct visual observation of microbubbles during insonification in vitro by a medical ultrasound imaging system. MET...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199812000-00004

    authors: Klibanov AL,Ferrara KW,Hughes MS,Wible JH Jr,Wojdyla JK,Dayton PA,Morgan KE,Brandenburger GH

    更新日期:1998-12-01 00:00:00

  • Radioimmunodetection of a transplantable human bladder carcinoma in a nude mouse.

    abstract::The results of an in vitro mixed hemadsorption (MHA) assay predicted the success of in vivo tumor localization using a radioiodinated, monoclonal, IgG1 antibody (A2) with reactivity to the human bladder carcinoma cell line RT4. In vitro, murine monoclonal antibodies A2 and G6, demonstrated reactivity to RT4 with titer...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198411000-00011

    authors: Gross MD,Skinner RW,Grossman HB

    更新日期:1984-11-01 00:00:00

  • Magnetic resonance imaging-controlled laser-induced interstitial thermotherapy.

    abstract:RATIONALE AND OBJECTIVES:Laser-induced interstitial thermotherapy (LITT) may become an attractive modality for minimally invasive tumor therapy. Magnetic resonance imaging (MRI) could be used to assist this procedure. METHODS:A T1-weighted turbo fast low-angle shot (FLASH) sequence for on-line monitoring of the laser-...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199403000-00015

    authors: Gewiese B,Beuthan J,Fobbe F,Stiller D,Müller G,Böse-Landgraf J,Wolf KJ,Deimling M

    更新日期:1994-03-01 00:00:00

  • The night stalker effect: quality improvements with a dedicated night-call rotation.

    abstract:RATIONALE AND OBJECTIVES:The authors assessed whether a non-sleep-deprived, second-year diagnostic radiology resident assigned to an after-hours "night stalker" emergency radiology (ER) rotation in an urban university hospital has a measurable impact on the number and clinical significance of "missed" radiologic findin...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199301000-00032

    authors: Mann FA,Danz PL

    更新日期:1993-01-01 00:00:00

  • Preclinical profile of the monodisperse iodinated macromolecular blood pool agent P743.

    abstract:RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200101000-00006

    authors: Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

    更新日期:2001-01-01 00:00:00

  • The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy.

    abstract::Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198507000-00009

    authors: Dae M,Canhasi B,Botvinick E,Olvera S,Schechtmann N,Engelstad B,Hattner R,Schiller N,O'Connell W,Faulkner D

    更新日期:1985-07-01 00:00:00

  • Fibroblast response to gadolinium: role for platelet-derived growth factor receptor.

    abstract:OBJECTIVE:The purpose of this study was to assess the effects of gadolinium (Gd3+), provided as gadolinium chloride, on fibroblast function. MATERIALS AND METHODS:Human dermal fibroblasts in monolayer culture and intact skin in organ culture were exposed to the lanthanide metal (1-20 μM). RESULTS:Increased proliferat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181e943d2

    authors: Bhagavathula N,Dame MK,DaSilva M,Jenkins W,Aslam MN,Perone P,Varani J

    更新日期:2010-12-01 00:00:00

  • Low-Dose Characterization of Kidney Stones Using Spectral Detector Computed Tomography: An Ex Vivo Study.

    abstract:OBJECTIVES:The aim of this study was to investigate the feasibility of kidney stone composition analysis using spectral detector computed tomography scanner (SDCT) with normal- and low-dose imaging protocols. METHODS:A total of 154 stones harvested from nephrolithotripsy or nephrolithotomy with a known monocrystalline...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000468

    authors: Große Hokamp N,Salem J,Hesse A,Holz JA,Ritter M,Heidenreich A,Maintz D,Haneder S

    更新日期:2018-08-01 00:00:00

  • Adenosine-stress dynamic myocardial CT perfusion imaging: initial clinical experience.

    abstract:OBJECTIVE:To evaluate the feasibility of adenosine-stress dynamic myocardial volume perfusion imaging with second generation dual source computed tomography (CT) for the qualitative and quantitative assessment of myocardial blood flow (MBF) compared with stress perfusion and viability magnetic resonance imaging (MRI). ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181dfa2f2

    authors: Bastarrika G,Ramos-Duran L,Rosenblum MA,Kang DK,Rowe GW,Schoepf UJ

    更新日期:2010-06-01 00:00:00

  • Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model.

    abstract:OBJECTIVE:There is little published information regarding the efficacy of paclitaxel-coated balloon catheters except for the iopromide-containing formulation, and less is known about the kind of toxicity at overdose. The aim of our study was to assess 2 different paclitaxel matrix formulations on angioplasty balloon ca...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31820577df

    authors: Kelsch B,Scheller B,Biedermann M,Clever YP,Schaffner S,Mahnkopf D,Speck U,Cremers B

    更新日期:2011-04-01 00:00:00

  • The potential of iosulamide meglumine as a contrast material for intravenous cholangiography: an experimental study in dogs.

    abstract::Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198105000-00016

    authors: Berk RN,Barnhart JL,Nazareno G,Witt BL

    更新日期:1981-05-01 00:00:00

  • Contrast-enhanced MRI of tumors. Comparison of Gd-DTPA and a macromolecular agent.

    abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198908000-00007

    authors: Wikström MG,Moseley ME,White DL,Dupon JW,Winkelhake JL,Kopplin J,Brasch RC

    更新日期:1989-08-01 00:00:00

  • Collateral arterial formation. Lymph draining ischemic kidneys contains a neovascular stimulating agent of high molecular weight.

    abstract::An agent has been identified in lymph from rat kidneys rendered ischemic by partial renal artery occlusion that induces a striking neovascular response in a hamster cheek-pouch assay system. The factor has a high molecular weight, cannot be identified in lymph from normal kidneys, and is associated with a marked incre...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198501000-00015

    authors: Hollenberg NK,Paskins-Hurlburt AJ,Abrams HL

    更新日期:1985-01-01 00:00:00

  • Detection and characterization of crystal suspensions using single-source dual-energy computed tomography: a phantom model of crystal arthropathies.

    abstract:OBJECTIVES:The aim of this study was to perform phantom measurements to prove the feasibility of single-source dual-energy computed tomography (DECT) of the extremities using a volume scan mode. In addition, we, for the first time, wanted to determine which concentrations of monosodium urate (MSU) in gout and calcium p...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000099

    authors: Diekhoff T,Kiefer T,Stroux A,Pilhofer I,Juran R,Mews J,Blobel J,Tsuyuki M,Ackermann B,Hamm B,Hermann KG

    更新日期:2015-04-01 00:00:00

  • Magnetic resonance imaging as a monitor of changes in the irradiated rat brain. An aid in determining the time course of events in a histologic study.

    abstract:RATIONALE AND OBJECTIVES:Optimal dose schedules and total dose of ionizing radiation for human central nervous system malignancy are not known. An animal model has been developed for the investigation of rat central nervous system response to proton irradiation using magnetic resonance imaging (MRI). A clinical MRI dev...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199504000-00003

    authors: Kennedy AS,Archambeau JO,Archambeau MH,Holshouser B,Thompson J,Moyers M,Hinshaw D Jr,Slater JM

    更新日期:1995-04-01 00:00:00

  • The effect of radiographic contrast media on leukocyte motility.

    abstract:RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199401000-00012

    authors: Roobottom CA,Farrow R,Wells IP,Hurlock-Fimls N

    更新日期:1994-01-01 00:00:00

  • Potential of dose reduction after marker placement with full-field digital mammography.

    abstract:OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000163743.63063.9f

    authors: Riedl CC,Jaromi S,Floery D,Pfarl G,Fuchsjaeger MH,Helbich TH

    更新日期:2005-06-01 00:00:00

  • Biodistribution and excretion of 125I ioversol in conscious dogs.

    abstract::Radiolabeled ioversol was injected intravenously into two male and two female beagle dogs (6.7 to 10.4 kg) at two dose levels each (0.2 and 1.0 g I/kg). Blood levels of radioactivity were monitored at 2, 5, 10, 20, 40, 60, 90, and 120 minutes and at one and two days. Urine and feces were collected in metabolism cages ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198906001-00005

    authors: Coveney JR,Robbins MS

    更新日期:1989-06-01 00:00:00

  • Opacification phase effects of angiographic contrast medium on left ventricular size and function: influence of initial ventricular volume and the pericardium.

    abstract::Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198209000-00009

    authors: LeWinter MM,Pavelec RS

    更新日期:1982-09-01 00:00:00

  • Structured Reporting of Rectal Magnetic Resonance Imaging in Suspected Primary Rectal Cancer: Potential Benefits for Surgical Planning and Interdisciplinary Communication.

    abstract:OBJECTIVES:The aim of this study was to evaluate the effect of structured reports (SRs) in comparison to nonstructured, free-text (FT) rectal magnetic resonance imaging (MRI) reports in patients with histologically proven rectal cancer and potential effects of both types of reporting on referring surgeons' satisfaction...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000336

    authors: Nörenberg D,Sommer WH,Thasler W,DʼHaese J,Rentsch M,Kolben T,Schreyer A,Rist C,Reiser M,Armbruster M

    更新日期:2017-04-01 00:00:00

  • Application of direct cannulation and injection lymphangiography to the study of the canine cardiac and pulmonary efferent mediastinal lymphatics.

    abstract::Lymphangiograms of canine cardiac and pulmonary efferent mediastinal lymphatics were made by cannulation and injection of Ethiodol. Injections were made singly and serially. The mediastinal lymphatics and lymph nodes, which constitute the pathways of drainage of the heart and lungs, were delineated from the point of c...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197901000-00012

    authors: Leeds SE,Uhley HN,Meister RB

    更新日期:1979-01-01 00:00:00

  • CT Dosimetry: What Has Been Achieved and What Remains to Be Done.

    abstract::Radiation dose in computed tomography (CT) has become a hot topic due to an upward trend in the number of CT procedures worldwide and the relatively high doses associated with these procedures. The main aim of this review article is to provide an overview of the most frequently used metrics for CT radiation dose chara...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000727

    authors: Damilakis J

    更新日期:2021-01-01 00:00:00

  • Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro.

    abstract:RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199510000-00006

    authors: Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

    更新日期:1995-10-01 00:00:00

  • MR cholangiopancreatography at 3.0 T: intraindividual comparative study with MR cholangiopancreatography at 1.5 T for clinical patients.

    abstract:OBJECTIVES:To prospectively evaluate the image quality and diagnostic accuracy of magnetic resonance cholangiopancreatography (MRCP) at 3.0 T compared with that at 1.5 T used for patients. MATERIALS AND METHODS:This study was approved by our institutional review board, and informed consent was obtained from all patien...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181b4c0ae

    authors: Onishi H,Kim T,Hori M,Murakami T,Tatsumi M,Nakaya Y,Nakamoto A,Osuga K,Tomoda K,Nakamura H

    更新日期:2009-09-01 00:00:00