Preclinical profile of the monodisperse iodinated macromolecular blood pool agent P743.

abstract：OBJECTIVES:The aims of this study were to investigate and validate quantitative susceptibility mapping (QSM) for lesional iron quantification in cerebral cavernous malformations (CCMs). MATERIALS AND METHODS:Magnetic resonance imaging studies were performed in phantoms and 16 patients on a 3-T scanner. Susceptibility ...

journal_title：Investigative radiology

authors： Tan H,Liu T,Wu Y,Thacker J,Shenkar R,Mikati AG,Shi C,Dykstra C,Wang Y,Prasad PV,Edelman RR,Awad IA

更新日期：2014-07-01 00:00:00

abstract：:We measured the amounts of three types of radiographic contrast media (RCM) that could be entrapped in liposomes prepared by the dehydration-rehydration vesicle (DRV) technique. To make DRVs, one initially makes water-containing, small unilamellar vesicles, adds contrast media and lyophilizes the mixture. Upon rehydra...

journal_title：Investigative radiology

authors： Seltzer SE,Gregoriadis G,Dick R

更新日期：1988-02-01 00:00:00

abstract：:An ultrasound phantom was constructed simulating fetal femurs in amniotic fluid. Bones of 26, 36, 50, 58, and 70 mm, representative of gestational ages ranging from 17 to 36 weeks, were scanned with mechanical sector, phased sector, and linear array systems (ATL, Diasonics, Acuson, and GE). Measurements were made with...

journal_title：Investigative radiology

authors： Gamba JL,Bowie JD,Dodson WC,Hedlund LW

更新日期：1985-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...

journal_title：Investigative radiology

authors： Kubota Y,Kichikawa K,Uchida H,Maeda M,Nishimine K,Makutani S,Sakaguchi S,Yoshioka T,Ohishi H,Kimura Y

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The ...

journal_title：Investigative radiology

authors： Jost G,Pietsch H,Sommer J,Sandner P,Lengsfeld P,Seidensticker P,Lehr S,Hütter J,Sieber MA

更新日期：2009-02-01 00:00:00

abstract：:The residency program at the University of Pennsylvania offers a 1-month fellowship for senior residents in medical student education. Instructional philosophy, methods, and content are discussed, observed, practiced, and evaluated. Close supervision and immediate feedback provide training particularly needed by futur...

journal_title：Investigative radiology

authors： Troupin RH

更新日期：1990-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A computerized system that applies the case-based approach to training radiologists to diagnose brain tumors was designed. The authors attempted to provide residents a tool that supports their visual memory and inducts case-based reasoning. METHODS:A relational database with a digital image li...

journal_title：Investigative radiology

authors： Macura RT,Macura KJ,Toro VE,Binet EF,Trueblood JH,Ji K

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare quantitative and semiquantitative parameters (signal-to-noise ratio [SNR], contrast-to-noise ratio [CNR], image quality, diagnostic confidence) from a standard brain magnetic resonance imaging examination encompassing common neurological disorders such as demyelinating dis...

journal_title：Investigative radiology

authors： Springer E,Dymerska B,Cardoso PL,Robinson SD,Weisstanner C,Wiest R,Schmitt B,Trattnig S

更新日期：2016-08-01 00:00:00

abstract：:A method is presented for selective catheterization and filming of the small internal spermatic and proper hepatic arteries in rabbits. The angiograms thus obtained afford clear delineation of the vessels and their branches and can enhance radiographic investigation of a variety of experimental disease models. ...

journal_title：Investigative radiology

authors： Young S,Hollenberg NK

更新日期：1977-05-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate image quality of a spectral photon-counting detector (PCD) computed tomography (CT) system for evaluation of major arteries of the head and neck compared with conventional single-energy CT scans using energy-integrating detectors (EIDs). METHODS:In this institutional r...

journal_title：Investigative radiology

authors： Symons R,Reich DS,Bagheri M,Cork TE,Krauss B,Ulzheimer S,Kappler S,Bluemke DA,Pourmorteza A

更新日期：2018-03-01 00:00:00

abstract：:Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...

journal_title：Investigative radiology

authors： Burbank FH,Thompson WM

更新日期：1986-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...

journal_title：Investigative radiology

authors： Sijens PE,Den Heijer T,De Leeuw FE,De Groot JC,Achten E,Heijboer RJ,Hofman A,Breteler MM,Oudkerk M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:Demonstrate the usability of a new polyetheretherketone (PEEK)-based MR-compatible guidewire for renal artery catheterization, angioplasty, and stenting under MR-guidance using MR-visible markers, in vitro and in vivo. MATERIAL AND METHODS:The new 0.035'' guidewire with fiber-reinforced PEEK core, a soft ti...

journal_title：Investigative radiology

authors： Kos S,Huegli R,Hofmann E,Quick HH,Kuehl H,Aker S,Kaiser GM,Borm PJ,Jacob AL,Bilecen D

更新日期：2009-04-01 00:00:00

abstract：:An isotopic radiation source 125I was investigated for use in soft tissue radiaography, with particular attention to possible use in mammography for mass screening. Film sensitivities, exposure rates, absorbed doeses, contrast and resolution were determined, and compared to conventional x-ray units. It was found that ...

journal_title：Investigative radiology

authors： Fairchild R,Atkins HL,Lebowitz E,Greenberg D

更新日期：1975-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the feasibility of nonenhanced magnetic resonance angiography (MRA) of the lower extremities at 7 tesla (T). MATERIALS AND METHODS:Eight healthy volunteers were examined on a 7-T whole-body magnetic resonance system. For image acquisition, a custom-built 16-channel t...

journal_title：Investigative radiology

authors： Fischer A,Maderwald S,Orzada S,Johst S,Schäfer LC,Ladd ME,Nassenstein K,Umutlu L,Lauenstein TC

更新日期：2013-07-01 00:00:00

abstract：:A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

journal_title：Investigative radiology

authors： Sovak M,Siefert HM,Ranganathan R

更新日期：1980-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used magnetic resonance imaging (MRI) techniques to examine the effect of meningeal trauma produced by cisterna magna puncture on the integrity of the blood-cerebrospinal fluid barrier (BCB) in a rat model. METHODS:Intravenous gadolinium-DTPA (Gd-DTPA), a relaxation rate modifier w...

journal_title：Investigative radiology

authors： Walker JD,Martin MA,Potts DG,Lemaire C,Templeton DM

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Computed tomography (CT) and magnetic resonance imaging (MRI) are introduced as an alternative to traditional autopsy. The purpose of this study was to investigate their accuracy in mass estimation of liver and spleen. METHODS:In 44 cases, the weights of spleen and liver were estimated based on MRI and CT da...

journal_title：Investigative radiology

authors： Jackowski C,Thali MJ,Buck U,Aghayev E,Sonnenschein M,Yen K,Dirnhofer R,Vock P

更新日期：2006-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the potential of magnetic resonance imaging (MRI) for evaluating the evolution of tumor necrosis, the authors evaluated 28 VX2 carcinomas inoculated in the thigh muscles of rabbits. METHODS:MRI of VX2 carcinomas at 2.0 T was done with spin-echo technique 1 week (14 tumors) and 3 week...

journal_title：Investigative radiology

authors： Choi BI,Lee DH,Han MC

更新日期：1993-01-01 00:00:00

abstract：:Using real-time ultrasound, the motions of the tongue, hyoid bone, and larynx were monitored and timed during swallowing in ten normal subjects. A well-defined propulsive wave of the tongue was observed during swallowing a 5-cc water bolus. The body of the hyoid bone was identified on the ultrasound scan as a high ech...

journal_title：Investigative radiology

authors： Shawker TH,Sonies B,Hall TE,Baum BF

更新日期：1984-03-01 00:00:00

abstract：:The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...

journal_title：Investigative radiology

authors： Siegel EL,Bishop MD,Wetzel LH,Anderson WF,McMillan JH

更新日期：1991-02-01 00:00:00

abstract：:Advances in the field of magnetic resonance (MR) as it pertains to clinical diagnostic radiology are examined in this review on the basis of publications in Investigative Radiology over the past 2 years (2005-2006). The articles published during that timeframe are discussed, organizationally wise, by anatomic region w...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Gadolinium leakage in ocular structures (GLOS) was recently observed in fluid-attenuated inversion recovery (FLAIR) images obtained the day after an initial gadolinium injection in stroke patients. The specificity of GLOS to stroke and its mechanisms remain unclear. OBJECTIVE:We investigated the factors ass...

journal_title：Investigative radiology

authors： Galmiche C,Moal B,Marnat G,Sagnier S,Schweitzer C,Dousset V,Sibon I,Tourdias T

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVES:The aim of this work was to quantitatively evaluate the pharmacokinetic pattern of Gd-EOB-DTPA in a model of isolated and perfused mouse liver by using magnetic resonance imaging (MRI) and monochromatic quantitative computed tomography (MQCT). MATERIALS AND METHODS:For MQCT, perfusions were realized with th...

journal_title：Investigative radiology

authors： Segers J,Le Duc G,Laumonier C,Troprès I,Elst LV,Muller RN

更新日期：2005-09-01 00:00:00

abstract：:Attenuation correction (AC) is an essential step in the positron emission tomography (PET) data reconstruction process to provide accurate and quantitative PET images. The introduction of PET/magnetic resonance (MR) hybrid systems has raised new challenges but also possibilities regarding PET AC. While in PET/computed...

journal_title：Investigative radiology

authors： Paulus DH,Quick HH

更新日期：2016-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors assessed whether a non-sleep-deprived, second-year diagnostic radiology resident assigned to an after-hours "night stalker" emergency radiology (ER) rotation in an urban university hospital has a measurable impact on the number and clinical significance of "missed" radiologic findin...

journal_title：Investigative radiology

authors： Mann FA,Danz PL

更新日期：1993-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...

journal_title：Investigative radiology

authors： Truax AL,Chandnani VP,Chacko AK,Gonzalez DM

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...

journal_title：Investigative radiology

authors： Rempp H,Voigtländer M,Clasen S,Kempf S,Neugebauer A,Schraml C,Schmidt D,Claussen CD,Enderle MD,Goldberg SN,Pereira PL

更新日期：2009-12-01 00:00:00

abstract：:Receiver operating characteristic (ROC) analysis has been used in a broad variety of medical imaging studies during the past 15 years, and its advantages over more traditional measures of diagnostic performance are now clearly established. But despite the essential simplicity of the approach, workers in the field ofte...

journal_title：Investigative radiology

authors： Metz CE

更新日期：1989-03-01 00:00:00

abstract：:French physicians must obtain their patient's consent before carrying out an action that interferes with the patient's corporal integrity. The doctor must use simple, approximate, intelligent, and honest words that help the patient to reach the indispensable decision. Proof of lack of consent lies with the patient. Th...

journal_title：Investigative radiology

authors： Alméras JP,Husson R,Moreau JF

更新日期：1988-09-01 00:00:00