Necrotic areas in VX2 carcinoma of rabbits. Correlation of magnetic resonance imaging and pathologic appearance.

Abstract:

RATIONALE AND OBJECTIVES:To assess the potential of magnetic resonance imaging (MRI) for evaluating the evolution of tumor necrosis, the authors evaluated 28 VX2 carcinomas inoculated in the thigh muscles of rabbits. METHODS:MRI of VX2 carcinomas at 2.0 T was done with spin-echo technique 1 week (14 tumors) and 3 weeks (14 tumors) after the inoculation of tumor cells. T1- and T2-weighted images were obtained with 500/30 and 2,500/80 sequences; the authors also performed enhanced T1-weighted images with contrast medium. MRI and histopathologic findings were compared. RESULTS:Enhanced T1-weighted images with gadolinium-DTPA (Gd-DTPA) (dimeglumine gadopentetate) could depict necrosis in almost all tumors (27/28) and were the most sensitive technique followed by T2- and T1-weighted images. T2-weighted images best permitted the evaluation of the characteristics of necrotic areas in VX2 carcinomas, followed by T1-weighted images with contrast enhancement, and unenhanced T1-weighted images. On T2-weighted images, low-intensity areas of necrotic areas correspond to areas of early necrosis, isointense areas corresponded to areas of intermediate necrosis, and high-intensity areas corresponded to the late phase of necrosis. CONCLUSIONS:MRI is useful in depicting necrosis and characterizing different phases of necrosis in VX2 carcinomas.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Choi BI,Lee DH,Han MC

doi

10.1097/00004424-199301000-00010

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

33-8

issue

1

eissn

0020-9996

issn

1536-0210

journal_volume

28

pub_type

杂志文章
  • Analysis of edge-tracking errors inherent in fluoroscopic images of the beating heart.

    abstract:RATIONALE AND OBJECTIVES:Because of the complex relationships between the dynamic three-dimensional cardiac surface shape and its projected image, errors arise with the use of two-dimensional silhouettes to measure displacements of the heart. The character and frequency of such errors are examined. METHODS:A high-prec...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199403000-00004

    authors: McInerney JJ,Weldner PW,Herr MD,Copenhaver GL

    更新日期:1994-03-01 00:00:00

  • Long-term effect of irradiation on lymph node uptake of interstitially delivered nanoparticulate contrast media.

    abstract:RATIONALE AND OBJECTIVES:To characterize the long-term effects of therapeutic doses of ionizing radiation on the uptake and distribution of percutaneously delivered particulate contrast media in normal lymph nodes. METHODS:Two milliliters of an iodinated nanoparticle suspension (76 mg I/mL) was injected subcutaneously...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200003000-00007

    authors: Wisner ER,Théon A,Griffey SM,McIntire GL

    更新日期:2000-03-01 00:00:00

  • The pediatric tracheostomy: III). An appraisal of xerography.

    abstract::Comparatively new in the roentgen evaluation of infants and children, xerography would appear to be ideal for portraying the pediatric airway. Since the radiation dose of xerography is higher than conventional radiography, its image quality is the subject of careful scrutiny in a pediatric setting here described in 23...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197807000-00002

    authors: Scott JR,Kramer SS,Griscom NT

    更新日期:1978-07-01 00:00:00

  • Identifying tumor vascular permeability heterogeneity with magnetic resonance imaging contrast agents.

    abstract:RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200204000-00003

    authors: Aref M,Brechbiel M,Wiener EC

    更新日期:2002-04-01 00:00:00

  • Consistency of rotator-cuff calcifications. Observations on plain radiography, sonography, computed tomography, and at needle treatment.

    abstract:RATIONALE AND OBJECTIVES:The author analyzes findings of consistency of rotator-cuff calcifications found at ultrasound (US)-guided needle treatment compared with findings of plain radiography, US, and computed tomography (CT). METHODS:Twenty patients had rotator-cuff calcifications (mean diameter, 1.5 cm; range, 1.1-...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199605000-00010

    authors: Farin PU

    更新日期:1996-05-01 00:00:00

  • Estimation of chemical composition and density from computed tomography carried out at a number of energies.

    abstract::A method is presented by whichcomputed tomography scans carried out at a number of energies may be utilized to obtain cross-sectional images of density and atomic number in addition to the conventional array of linear attenuation coefficients. This type of analysis has been carried out for various substances of biolog...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197703000-00016

    authors: McDavid WD,Waggener RG,Dennis MJ,Sank VJ,Payne WH

    更新日期:1977-03-01 00:00:00

  • Can Ferumoxytol be Used as a Contrast Agent to Differentiate Between Acute and Chronic Inflammatory Kidney Disease?: Feasibility Study in a Rat Model.

    abstract:OBJECTIVES:Ferumoxytol, an intravenous iron supplement, can be used in off-label mode as a contrast agent in magnetic resonance imaging. The aim of this study was to assess whether ferumoxytol can be used as a marker of inflammation in animal models of acute and chronic inflammatory kidney diseases. MATERIAL AND METHO...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000209

    authors: Budjan J,Neudecker S,Schock-Kusch D,Kraenzlin B,Schoenberg SO,Michaely HJ,Attenberger UI

    更新日期:2016-02-01 00:00:00

  • Multislice CT angiography of the iliac arteries in the presence of various stents: in vitro evaluation of artifacts and lumen visibility.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the imaging characteristics of various iliac artery stents and stent-grafts in a multislice, computed tomography angiography (MSCTA) phantom study. METHODS:Twelve types of stents and three stent-grafts made of different materials (steel, nitinol, tantalum, cobalt-based alloy) were ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200112000-00004

    authors: Maintz D,Fischbach R,Juergens KU,Allkemper T,Wessling J,Heindel W

    更新日期:2001-12-01 00:00:00

  • Noninvasive measurement of an index of renal blood flow.

    abstract::A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198307000-00009

    authors: Powers TA,Rees RS,Bowen RD

    更新日期:1983-07-01 00:00:00

  • Increased urine histamine and contrast media reactions.

    abstract::Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198403000-00007

    authors: Kaliner M,Dyer J,Merlin S,Shelton A,Greenhill A,Treadwell G,McKenna W,Lieberman P

    更新日期:1984-03-01 00:00:00

  • Phase I clinical evaluation of citrate-coated monocrystalline very small superparamagnetic iron oxide particles as a new contrast medium for magnetic resonance imaging.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the safety and pharmacokinetics of a newly developed MR contrast medium consisting of very small superparamagnetic iron oxide particles (VSOP) coated with citrate (VSOP-C184) in a clinical phase I trial. METHODS:A total of 18 healthy subjects received either VSOP-C184 (core diamete...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.rli.0000129472.45832.b0

    authors: Taupitz M,Wagner S,Schnorr J,Kravec I,Pilgrimm H,Bergmann-Fritsch H,Hamm B

    更新日期:2004-07-01 00:00:00

  • Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: initial results using highly accelerated parallel acquisition.

    abstract:OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.rli.0000236992.21065.04

    authors: Nael K,Fenchel M,Salamon N,Duckwiler GR,Laub G,Finn JP,Villablanca JP

    更新日期:2006-10-01 00:00:00

  • Model-based iterative reconstruction technique for ultralow-dose computed tomography of the lung: a pilot study.

    abstract:OBJECTIVES:The aim of this study was to assess the effectiveness of a model-based iterative reconstruction (MBIR) in improving image quality and diagnostic performance of ultralow-dose computed tomography (ULDCT) of the lung. MATERIALS AND METHODS:The institutional review board approved this study, and all patients pr...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182562a89

    authors: Yamada Y,Jinzaki M,Tanami Y,Shiomi E,Sugiura H,Abe T,Kuribayashi S

    更新日期:2012-08-01 00:00:00

  • Applications of voxel shifting in magnetic resonance imaging.

    abstract::Due to the nature of three-dimensional Fourier transform (3-DFT) data acquisition in magnetic resonance imaging (MRI), the spatial relation between a resolved volume element (a voxel) and the object can be manipulated easily. Those manipulations have practical consequences in terms of registering slice positions with ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199012000-00006

    authors: Kramer D,Li A,Simovsky I,Hawryszko C,Hale J,Kaufman L

    更新日期:1990-12-01 00:00:00

  • Interference of gadolinium-containing contrast-enhancing agents with colorimetric calcium laboratory testing.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000170447.45577.5e

    authors: Löwe A,Balzer T,Hirt U

    更新日期:2005-08-01 00:00:00

  • Changes in portal hemodynamics and acute rejection in the first 2 weeks after orthotopic liver transplantation. A prospective Doppler ultrasound study.

    abstract:RATIONALE AND OBJECTIVES:To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS:Recordings were obtai...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199612000-00007

    authors: Kok T,Slooff MJ,Peeters PM,Zwaveling JH,Bijleveld CM,Gi-van Loon CE,Klompmaker IJ,Haagsma EB

    更新日期:1996-12-01 00:00:00

  • Evolution of the ablation region after magnetic resonance-guided high-intensity focused ultrasound ablation in a Vx2 tumor model.

    abstract:OBJECTIVES:Volumetric magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) is a completely noninvasive image-guided thermal ablation technique. Recently, there has been growing interest in the use of MR-HIFU for noninvasive ablation of malignant tumors. Of particular interest for noninvasive ablation...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182820257

    authors: Wijlemans JW,Deckers R,van den Bosch MA,Seinstra BA,van Stralen M,van Diest PJ,Moonen CT,Bartels LW

    更新日期:2013-06-01 00:00:00

  • A large animal model (swine) to study the diagnosis and treatment of cholelithiasis.

    abstract::Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198902000-00005

    authors: Griffith SL,Burney BT,Fry FJ,Franklin TD Jr

    更新日期:1989-02-01 00:00:00

  • Nonenhanced magnetic resonance angiography of the lower extremity vessels at 7 tesla: initial experience.

    abstract:OBJECTIVES:The aim of this study was to investigate the feasibility of nonenhanced magnetic resonance angiography (MRA) of the lower extremities at 7 tesla (T). MATERIALS AND METHODS:Eight healthy volunteers were examined on a 7-T whole-body magnetic resonance system. For image acquisition, a custom-built 16-channel t...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182839c2b

    authors: Fischer A,Maderwald S,Orzada S,Johst S,Schäfer LC,Ladd ME,Nassenstein K,Umutlu L,Lauenstein TC

    更新日期:2013-07-01 00:00:00

  • Structured Reporting of Rectal Magnetic Resonance Imaging in Suspected Primary Rectal Cancer: Potential Benefits for Surgical Planning and Interdisciplinary Communication.

    abstract:OBJECTIVES:The aim of this study was to evaluate the effect of structured reports (SRs) in comparison to nonstructured, free-text (FT) rectal magnetic resonance imaging (MRI) reports in patients with histologically proven rectal cancer and potential effects of both types of reporting on referring surgeons' satisfaction...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000336

    authors: Nörenberg D,Sommer WH,Thasler W,DʼHaese J,Rentsch M,Kolben T,Schreyer A,Rist C,Reiser M,Armbruster M

    更新日期:2017-04-01 00:00:00

  • Application of direct cannulation and injection lymphangiography to the study of the canine cardiac and pulmonary efferent mediastinal lymphatics.

    abstract::Lymphangiograms of canine cardiac and pulmonary efferent mediastinal lymphatics were made by cannulation and injection of Ethiodol. Injections were made singly and serially. The mediastinal lymphatics and lymph nodes, which constitute the pathways of drainage of the heart and lungs, were delineated from the point of c...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197901000-00012

    authors: Leeds SE,Uhley HN,Meister RB

    更新日期:1979-01-01 00:00:00

  • Alteration of human tumor cell adhesion by high-strength static magnetic fields.

    abstract:RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199210000-00014

    authors: Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

    更新日期:1992-10-01 00:00:00

  • Dose response to Paclitaxel-coated balloon catheters in the porcine coronary overstretch and stent implantation model.

    abstract:OBJECTIVE:There is little published information regarding the efficacy of paclitaxel-coated balloon catheters except for the iopromide-containing formulation, and less is known about the kind of toxicity at overdose. The aim of our study was to assess 2 different paclitaxel matrix formulations on angioplasty balloon ca...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31820577df

    authors: Kelsch B,Scheller B,Biedermann M,Clever YP,Schaffner S,Mahnkopf D,Speck U,Cremers B

    更新日期:2011-04-01 00:00:00

  • Perfusion quantitation by ultrafast computed tomography.

    abstract::Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-199212002-00004

    authors: Gould RG

    更新日期:1992-12-01 00:00:00

  • Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions.

    abstract:OBJECTIVES:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS:Twenty patients with known or suspected focal liver lesions underwent liver MRI usi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31816200b5

    authors: Zech CJ,Herrmann KA,Dietrich O,Horger W,Reiser MF,Schoenberg SO

    更新日期:2008-04-01 00:00:00

  • Influence of paramagnetic ions and pH on proton NMR relaxation of biologic fluids.

    abstract::The extent to which various concentrations of the paramagnetic metal ions [gadolinium (III), manganese (II), chromium (III), iron (III), nickel (II), copper (II), and cobalt (II)] affect proton magnetic relaxation times of distilled water, 4% human serum albumin (HSA), and dog plasma was studied in vitro. The pH of wa...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198602000-00009

    authors: Barnhart JL,Berk RN

    更新日期:1986-02-01 00:00:00

  • Clinical and High-Resolution CT Features of the COVID-19 Infection: Comparison of the Initial and Follow-up Changes.

    abstract:OBJECTIVES:In late December 2019, an outbreak of coronavirus disease (COVID-19) in Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory syndrome coronavirus 2. We aimed to quantify the severity of COVID-19 infection on high-resolution chest computed tomography (CT) and to determine its r...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000674

    authors: Xiong Y,Sun D,Liu Y,Fan Y,Zhao L,Li X,Zhu W

    更新日期:2020-06-01 00:00:00

  • Comprehensive assessment of renal function and vessel morphology in potential living kidney donors: an MRI-based approach.

    abstract:OBJECTIVES:To test the feasibility of a single MR-based examination allowing for the comprehensive assessment of renal anatomy, function, and vascular status in candidates for kidney transplantation. MATERIALS AND METHODS:Twelve healthy potential kidney donors (mean age: 47 +/- 14 [standard deviation] years, 3 men and...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/RLI.0b013e3181b35a70

    authors: Rossi C,Boss A,Artunc F,Yildiz S,Martirosian P,Dittmann H,Claussen CD,Heyne N,Schick F,Schlemmer HP

    更新日期:2009-11-01 00:00:00

  • Effects of iodinated x-ray contrast media on renal epithelial cells in culture.

    abstract:RATIONALE AND OBJECTIVES:To study cellular mechanisms that cause contrast media nephropathy, an in vitro system for proximal and distal tubular cells has been established to evaluate the influence of x-ray contrast media on tubular function. METHODS:Confluent cell cultures of the two renal cell lines, proximal tubule ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199411000-00002

    authors: Andersen KJ,Christensen EI,Vik H

    更新日期:1994-11-01 00:00:00

  • MRI dosimetry: a fast quantitative MRI method to determine 3D absorbed dose distributions.

    abstract:RATIONALE AND OBJECTIVES:Magnetic resonance imaging (MRI) techniques seem to be very promising for 3D dosimetry studies, but long imaging acquisition time limits their use. A new fast T1 mapping protocol, easy to implement on a conventional MR imager, has been used to determine dose distributions on Fricke gels. METHO...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199903000-00014

    authors: Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

    更新日期:1999-03-01 00:00:00