Retention of iodine and expression of biomarkers for renal damage in the kidney after application of iodinated contrast media in rats.

abstract：OBJECTIVES:To test the feasibility of a single MR-based examination allowing for the comprehensive assessment of renal anatomy, function, and vascular status in candidates for kidney transplantation. MATERIALS AND METHODS:Twelve healthy potential kidney donors (mean age: 47 +/- 14 [standard deviation] years, 3 men and...

journal_title：Investigative radiology

authors： Rossi C,Boss A,Artunc F,Yildiz S,Martirosian P,Dittmann H,Claussen CD,Heyne N,Schick F,Schlemmer HP

更新日期：2009-11-01 00:00:00

abstract：:The issue of dechelation (transmetallation) in vivo after administration of the linear gadolinium-based contrast agents, and potential safety concerns, is considered on the basis of an extensive, focused literature review. Early indications of potential problems included the high level of excess ligand used in the for...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2018-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To improve the accuracy of magnetic resonance imaging (MRI) in evaluating the response of osteosarcomas to preoperative chemotherapy, the authors developed a technique of mapping tumor necrosis and viability by quantitating slope values of gadolinium-DTPA (Gd-DTPA) uptake on dynamic fast low-an...

journal_title：Investigative radiology

authors： Hanna SL,Parham DM,Fairclough DL,Meyer WH,Le AH,Fletcher BD

更新日期：1992-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Interstitial laser photocoagulation (ILP) causes localized tissue necrosis. This study was performed to determine 1) whether the changes seen on computed tomography (CT) correspond to the necrosis pathologically, and 2) which CT technique best shows the necrosis. METHODS:Eighteen Wistar rats h...

journal_title：Investigative radiology

authors： Amin Z,Thurrell W,Spencer GM,Harries SA,Grant WE,Bown SG,Lees WR

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

journal_title：Investigative radiology

authors： Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

更新日期：2015-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of the study was to evaluate the effect of articular fluid distention on patellar position at different degrees of knee angulation. METHODS:Patellar position in 10 cadaveric knee specimens was determined with 30, 100, and 200 mm Hg joint distention at 45, 20, and 5 degrees of knee ...

journal_title：Investigative radiology

authors： Brossmann J,Koch S,Schwarzenberg H,Link J,Muhle C,Bull CC,Heller M

更新日期：1996-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

journal_title：Investigative radiology

authors： Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVES:: To evaluate the performance of a gadolinium-based contrast compound (P846) as well as an ultra-small particle of iron oxide agent (P904) in contrast-enhanced magnetic resonance angiography (MRA) in rabbits and to compare those agents with gadoterate meglumine (Gd-DOTA) for first pass and steady state imagi...

journal_title：Investigative radiology

authors： Kinner S,Maderwald S,Parohl N,Albert J,Corot C,Robert P,Barkhausen J,Vogt FM

更新日期：2011-08-01 00:00:00

abstract：:A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...

journal_title：Investigative radiology

authors： Pitrè D,Felder E

更新日期：1980-11-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...

journal_title：Investigative radiology

authors： Rempp H,Voigtländer M,Clasen S,Kempf S,Neugebauer A,Schraml C,Schmidt D,Claussen CD,Enderle MD,Goldberg SN,Pereira PL

更新日期：2009-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The relative stability and selectivity of magnetic resonance (MR) imaging contrast agents were compared with in vitro transmetallation and ligand competition reactions. MATERIALS AND METHODS:A gadolinium (Gd)-DTPA-BIGA, Gd-DTPA-BMA, Gd-DTPA, or Gd-HP-DO3A solution was mixed with an equimolar s...

journal_title：Investigative radiology

authors： Puttagunta NR,Gibby WA,Puttagunta VL

更新日期：1996-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Bolus injection of iodinated contrast media has been observed to alter myocardial mechanical function, but the consequences on cellular metabolism are poorly documented. Modifications of metabolic parameters (intracellular pH as well as adenosine triphosphate [ATP], phosphocreatine, and inorgan...

journal_title：Investigative radiology

authors： Goossens A,Vander Elst L,Van Haverbeke Y,Muller RN

更新日期：1995-01-01 00:00:00

abstract：:We have examined the effect of dose on contrast medium-induced reductions in glomerular filtration in anesthetized rabbits. The fraction of renal plasma flow that is filtered, the filtration fraction, was directly measured by the renal arteriovenous difference method using technetium-99m (99mTc) (Sn) DTPA as the trace...

journal_title：Investigative radiology

authors： Harvey LA,Caldicott WJ

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVES:In late December 2019, an outbreak of coronavirus disease (COVID-19) in Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory syndrome coronavirus 2. We aimed to quantify the severity of COVID-19 infection on high-resolution chest computed tomography (CT) and to determine its r...

journal_title：Investigative radiology

authors： Xiong Y,Sun D,Liu Y,Fan Y,Zhao L,Li X,Zhu W

更新日期：2020-06-01 00:00:00

abstract：:Due to the small size of the bronchial arteries, the bronchial circulation is difficult to study and remains poorly understood. We have utilized single photon emission computed tomography (SPECT) as a noninvasive means of studying the bronchial circulation. Imaging studies were performed in sheep before and after the ...

journal_title：Investigative radiology

authors： Chiles C,Newman GE,Blinder RA

更新日期：1990-01-01 00:00:00

abstract：:An ultrasound phantom was constructed simulating fetal femurs in amniotic fluid. Bones of 26, 36, 50, 58, and 70 mm, representative of gestational ages ranging from 17 to 36 weeks, were scanned with mechanical sector, phased sector, and linear array systems (ATL, Diasonics, Acuson, and GE). Measurements were made with...

journal_title：Investigative radiology

authors： Gamba JL,Bowie JD,Dodson WC,Hedlund LW

更新日期：1985-05-01 00:00:00

abstract：:The rates at which the paramagnetic compounds deoxyhemoglobin (Hb) and methemoglobin (MHb) form in vivo within an area of hemorrhage are unknown. The present experiment establishes the baseline concentrations and rates of change in paramagnetic hemoglobin concentrations, as well as the pH in normal heparinized and clo...

journal_title：Investigative radiology

authors： Taber KH,Migliore PJ,Pagani JJ,Ford JJ,McLauren T,Hayman LA

更新日期：1990-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the safety and pharmacokinetics of a newly developed MR contrast medium consisting of very small superparamagnetic iron oxide particles (VSOP) coated with citrate (VSOP-C184) in a clinical phase I trial. METHODS:A total of 18 healthy subjects received either VSOP-C184 (core diamete...

journal_title：Investigative radiology

authors： Taupitz M,Wagner S,Schnorr J,Kravec I,Pilgrimm H,Bergmann-Fritsch H,Hamm B

更新日期：2004-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...

journal_title：Investigative radiology

authors： Berthezène Y,Croisille P,Bertocchi M,Houzard C,Bendib K,Revel D

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

journal_title：Investigative radiology

authors： Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

更新日期：2015-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

journal_title：Investigative radiology

authors： Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to assess the feasibility of magnetic resonance cholangiography (MRC) using biliary-secreted gadoxetic acid at 7 T and to compare it with T2-weighted (w) MRC at 3 T. MATERIALS AND METHODS:Ten healthy volunteers were examined on a 7-T whole-body magnetic resonance system. T2...

journal_title：Investigative radiology

authors： Fischer A,Kraff O,Orzada S,Nensa F,Schäfer LC,Ladd ME,Umutlu L,Lauenstein TC

更新日期：2014-05-01 00:00:00

abstract：:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

journal_title：Investigative radiology

authors： Gould RG

更新日期：1992-12-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...

journal_title：Investigative radiology

authors： Maubon A,Rouanet JP,Laurent A,Joujoux JM,Cover S,Courtieu C,Wassef M,Godlewski G,Honiger J,Lopez FM

更新日期：1994-02-01 00:00:00

abstract：PURPOSE:To evaluate the technical feasibility of high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) with highly accelerated parallel acquisition at 3.0 T using a 32-channel phased array coil, and a high relaxivity contrast agent. MATERIALS AND METHODS:Ten adult healthy volunteers (5 men,...

journal_title：Investigative radiology

authors： Nael K,Fenchel M,Krishnam M,Finn JP,Laub G,Ruehm SG

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...

journal_title：Investigative radiology

authors： Löwe A,Balzer T,Hirt U

更新日期：2005-08-01 00:00:00

abstract：:The potential of magnetic resonance imaging (MRI) quantification of calcium for the evaluation of pulmonary nodules was investigated in simulated nodules. Calcium salts do not contain mobile protons and thus have no signal on MR proton images. To determine whether the absence of signal from partially calcified nodules...

journal_title：Investigative radiology

authors： Gamsu G,de Geer G,Cann C,Müller N,Brito A

更新日期：1987-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...

journal_title：Investigative radiology

authors： Oudkerk M,Sijens PE,Van Beek EJ,Kuijpers TJ

更新日期：1995-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...

journal_title：Investigative radiology

authors： Aguado F,Revilla M,Hernández ER,Villa LF,Rico H

更新日期：1997-01-01 00:00:00

abstract：:Pyelovenous and pyelolymphatic backflow have been observed during retrograde pyelography in three patients with renal vein thrombosis. The radiographic patterns of backflow following experimental unilateral renal vein occlusion in rabbits were analyzed and correlated with the clinical findings. Capsular, perihilar, pe...

journal_title：Investigative radiology

authors： Bidgood WD Jr,Cuttino JT Jr,Clark RL,Volberg FM

更新日期：1981-01-01 00:00:00