Hybrid Positron Emission Tomography/Magnetic Resonance Imaging: Challenges, Methods, and State of the Art of Hardware Component Attenuation Correction.

Abstract:

:Attenuation correction (AC) is an essential step in the positron emission tomography (PET) data reconstruction process to provide accurate and quantitative PET images. The introduction of PET/magnetic resonance (MR) hybrid systems has raised new challenges but also possibilities regarding PET AC. While in PET/computed tomography (CT) imaging, CT images can be converted to attenuation maps, MR images in PET/MR do not provide a direct relation to attenuation. For the AC of patient tissues, new methods have been suggested, for example, based on image segmentation, atlas registration, or ultrashort echo time MR sequences. Another challenge in PET/MR hybrid imaging is AC of hardware components that are placed in the PET/MR field of view, such as the patient table or various radiofrequency (RF) coils covering the body of the patient for MR signal detection. Hardware components can be categorized into 4 different groups: (1) patient table, (2) RF receiver coils, (3) radiation therapy equipment, and (4) PET and MR imaging phantoms. For rigid and stationary objects, such as the patient table and some RF coils like the head/neck coil, predefined CT-based attenuation maps stored on the system can be used for automatic AC. Flexible RF coils are not included into the AC process till now because they can vary in position as well as in shape and are not accurately detectable with the PET/MR system.This work summarizes challenges, established methods, new concepts, and the state of art in hardware component AC in the context of PET/MR hybrid imaging. The work also gives an overview of PET/MR hardware devices, their attenuation properties, and their effect on PET quantification.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Paulus DH,Quick HH

doi

10.1097/RLI.0000000000000289

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

624-34

issue

10

eissn

0020-9996

issn

1536-0210

journal_volume

51

pub_type

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