Developments in X-Ray Contrast Media and the Potential Impact on Computed Tomography.

abstract：RATIONALE AND OBJECTIVES:The aim of the study was to examine the effects of azelastine on proliferation, clonogenic activity, cell-cycle, and migration of human aortic smooth-muscle cells (haSMCs) in vitro. METHODS:HaSMCs were treated for 4 days with azelastine (1 micromol/L, 25 micromol/L, 50 micromol/L). Half of the...

journal_title：Investigative radiology

authors： Schöber W,Wiskirchen J,Kehlbach R,Gebert R,Rodegerdts E,Betsch A,Johst U,Feuls R,Claussen CD,Duda SD

更新日期：2002-05-01 00:00:00

abstract：:The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...

journal_title：Investigative radiology

authors： Ferrante SL,Schreiman JS,Rouse JW,Rysavy JA,Cheng SC,Frick MP

更新日期：1990-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate image mottle in conventional CT images of the abdomen as a function of radiographic technique factors and patient size. METHODS:Water-filled phantoms simulating the abdomens of adult (32 cm in diameter) and pediatric (16 cm in diameter) patients were used to investigate image mo...

journal_title：Investigative radiology

authors： Ende JF,Huda W,Ros PR,Litwiller AL

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to conduct a radiopathologic evaluation of right-angled traction bronchiectasis to differentiate idiopathic pulmonary fibrosis (IPF) without honeycombing from idiopathic nonspecific interstitial pneumonia (NSIP). MATERIALS AND METHODS:The derivation cohort included 78 consecutive p...

journal_title：Investigative radiology

authors： Kim H,Yoon SH,Lee HJ,Song SG,Koh J,Jeon YK,Chae KJ,Jin GY,Jin KN,Lee KY,Goo JM

更新日期：2020-06-01 00:00:00

abstract：:Radiation dose in computed tomography (CT) has become a hot topic due to an upward trend in the number of CT procedures worldwide and the relatively high doses associated with these procedures. The main aim of this review article is to provide an overview of the most frequently used metrics for CT radiation dose chara...

journal_title：Investigative radiology

authors： Damilakis J

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Dynamic ventilation (3)He-MRI is a new method to assess pulmonary gas inflow. As differing airway diameters throughout the ventilatory cycle can influence gas inflow this study intends to investigate the influence of volume and timing of a He gas bolus with respect to the beginning of the tidal volume on insp...

journal_title：Investigative radiology

authors： Gast KK,Hawig K,Windirsch M,Markstaller K,Schreiber WG,Schmiedeskamp J,Düber C,Kauczor HU,Heussel CP

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific dif...

journal_title：Investigative radiology

authors： Maas MC,Litjens GJS,Wright AJ,Attenberger UI,Haider MA,Helbich TH,Kiefer B,Macura KJ,Margolis DJA,Padhani AR,Selnæs KM,Villeirs GM,Fütterer JJ,Scheenen TWJ

更新日期：2019-07-01 00:00:00

abstract：MATERIALS AND METHODS:Stenotic kidney (STK) and contralateral kidney magnetization transfer ratios (MTRs; Mt/M0) were measured at 3.0-T magnetic resonance imaging, at offset frequencies of 600 and 1000 Hz, before and 1 month post-PTRA in 7 RVD pigs. Stenotic kidney MTR was correlated to renal perfusion, renal blood flo...

journal_title：Investigative radiology

authors： Afarideh M,Jiang K,Ferguson CM,Woollard JR,Glockner JF,Lerman LO

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to optimize computed tomography (CT) surveillance of skeletal metastases in patients with breast cancer through the use of osseous subtraction maps between baseline and follow-up examinations created by a novel software algorithm. The new postprocessing algorithm segments the origina...

journal_title：Investigative radiology

authors： Horger M,Thaiss WM,Wiesinger B,Ditt H,Fritz J,Nikolaou K,Kloth C

更新日期：2017-02-01 00:00:00

abstract：:The sonographic appearance of kidneys in patients presenting with acute renal failure due to hemolytic-uremic syndrome (HUS) was evaluated and compared with that in an age-matched control series. In nine patients with HUS, the renal cortex was typically hyperechogenic and the renal pyramids appeared sonolucent. The re...

journal_title：Investigative radiology

authors： Kenney PJ,Brinsko RE,Patel DV,Spitzer RE,Farrar FM

更新日期：1986-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Hypertonic X-ray contrast media induce morphologic changes in red blood cells (RBCs) and reduce their deformability when measured in vitro. This study investigated whether RBCs treated with hypertonic contrast media could induce circulatory as well as metabolic disturbances in vivo. METHODS:Au...

journal_title：Investigative radiology

authors： Miyazawa T,Murayama C,Yamanaka T,Fritz-Zieroth B

更新日期：1993-09-01 00:00:00

abstract：:Left ventricular volume has been measured with ultrafast computed tomography. However, the accuracy with which this can be done is unknown. We therefore imaged with ultrafast computed tomography 11 rectangular phantoms, 20 to 225 ml, and 17 left ventricular casts, 15 to 112 ml. Two observers planimetered serial tomogr...

journal_title：Investigative radiology

authors： Pietras RJ,Wolfkiel CJ,Veselik K,Roig E,Chomka EV,Brundage BH

更新日期：1991-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：:Advances in the field of magnetic resonance (MR) as it pertains to clinical diagnostic radiology are examined in this review on the basis of publications in Investigative Radiology over the past 2 years (2005-2006). The articles published during that timeframe are discussed, organizationally wise, by anatomic region w...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2006-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors synthesized and tested a novel hydrogel system proposed for use in extra- and intravascular radiologic interventions, such as chemoembolizations and embolizations, and as a vehicle for sustained drug release. MATERIALS:The material was specifically designed to meet the prerequisite...

journal_title：Investigative radiology

authors： Weissleder R,Bogdanov A,Frank H,Nossiff N,Bogdanova A,Schaffer BK,Brady T,Wittenberg J

更新日期：1993-12-01 00:00:00

abstract：:We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...

journal_title：Investigative radiology

authors： Hayakawa K,Yamashita K

更新日期：1989-04-01 00:00:00

abstract：:Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...

journal_title：Investigative radiology

authors： Schuhmann-Giampieri G,Schmitt-Willich H,Frenzel T,Press WR,Weinmann HJ

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...

journal_title：Investigative radiology

authors： Maroules CD,McColl R,Khera A,Peshock RM

更新日期：2008-09-01 00:00:00

abstract：:Gallbladder sclerotherapy after permanent cystic duct occlusion, to prevent gallstone recurrence in nonsurgical gallstone therapy, is at least a two-stage procedure. A balloon catheter was developed to perform gallbladder sclerotherapy with only temporary occlusion of the cystic duct, and the efficacy and safety of th...

journal_title：Investigative radiology

authors： Brakel K,Laméris JS,Vergunst H,Ten Kate FJ,Nijs HG,Terpstra OT

更新日期：1991-09-01 00:00:00

abstract：:Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

journal_title：Investigative radiology

authors： Cuttino JT Jr,Goss FU,Clark RL,Marr MC

更新日期：1981-03-01 00:00:00

abstract：:The authors present a numerical deconvolution technique to compensate for image degrading effects caused by scattered photons in radiographic chest images. Fourier transform techniques are used to deconvolve a shift invariant model of the two dimensional point spread response functions of the scattered radiation. This...

journal_title：Investigative radiology

authors： Floyd CE,Beatty PT,Ravin CE

更新日期：1989-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The capability of an indirect computed tomographic lymphography (CT-LG) using a nonionic monometric contrast medium iopamidol for visualizing breast lymphatic pathways was preliminarily tested. MATERIALS AND METHODS:In 10 female dogs, a total of 0.5 and 1 mL of undiluted iopamidol was injected...

journal_title：Investigative radiology

authors： Suga K,Ogasawara N,Yuan Y,Okada M,Matsunaga N,Tangoku A

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to prospectively compare diagnostic performance and time efficiency of a double-reading paradigm in which a first-reader computer-aided detection (CAD) is followed by a fast 2-dimensional review (DR FR-CAD) with those of a double reading with second-reader CAD (SR CAD). MATER...

journal_title：Investigative radiology

authors： Iussich G,Correale L,Senore C,Hassan C,Segnan N,Campanella D,Bert A,Galatola G,Laudi C,Regge D

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...

journal_title：Investigative radiology

authors： Riedl CC,Jaromi S,Floery D,Pfarl G,Fuchsjaeger MH,Helbich TH

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:X-ray computed tomography (CT) using phase contrast can provide images with greatly enhanced soft-tissue contrast in comparison to conventional attenuation-based CT. We report on the first scan of a human specimen recorded with a phase-contrast CT system based on an x-ray grating interferometer and a convent...

journal_title：Investigative radiology

authors： Donath T,Pfeiffer F,Bunk O,Grünzweig C,Hempel E,Popescu S,Vock P,David C

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:The authors assessed the relative efficacy of conventional and digital storage-phosphor radiographs for the detection of skull fractures. METHODS:Fifty conventional film-screen radiographs (FSR) and 50 digital storage-phosphor radiographs (DR) with 66 fractures were compared. Five radiologists evaluated ima...

journal_title：Investigative radiology

authors： Langen HJ,Klein HM,Wein B,Stargardt A,Günther RW

更新日期：1993-08-01 00:00:00

abstract：:Skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin A and its derivatives. Recently, a new derivative, isotretinoin (Accutane, Hoffman-LaRoche, Inc.), has become available for the treatment of cystic acne. Ninety-six patients treated for a minimum of four...

journal_title：Investigative radiology

authors： Kilcoyne RF,Cope R,Cunningham W,Nardella FA,Denman S,Franz TJ,Hanifin J

更新日期：1986-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Bolus injection of iodinated contrast media has been observed to alter myocardial mechanical function, but the consequences on cellular metabolism are poorly documented. Modifications of metabolic parameters (intracellular pH as well as adenosine triphosphate [ATP], phosphocreatine, and inorgan...

journal_title：Investigative radiology

authors： Goossens A,Vander Elst L,Van Haverbeke Y,Muller RN

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to perform phantom measurements to prove the feasibility of single-source dual-energy computed tomography (DECT) of the extremities using a volume scan mode. In addition, we, for the first time, wanted to determine which concentrations of monosodium urate (MSU) in gout and calcium p...

journal_title：Investigative radiology

authors： Diekhoff T,Kiefer T,Stroux A,Pilhofer I,Juran R,Mews J,Blobel J,Tsuyuki M,Ackermann B,Hamm B,Hermann KG

更新日期：2015-04-01 00:00:00

abstract：:Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrat...

journal_title：Investigative radiology

authors： Richards TL,Terrier F,Sievers RE,Lipton MJ,Moseley ME,Higgins CB

更新日期：1987-08-01 00:00:00