Gelatin encapsulated nitrogen microbubbles as ultrasonic contrast agents.

Abstract:

:Gelatin encapsulated nitrogen microbubbles were effective ultrasonic contrast agents in in vitro phantom and in vivo rabbit V2 carcinoma studies. Intra-arterial injection of 80-micrometer gelatin encapsulated nitrogen microbubbles appeared to improve tumor visualization by rim enhancement, which persisted for several minutes.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Carroll BA,Turner RJ,Tickner EG,Boyle DB,Young SW

doi

10.1097/00004424-198005000-00013

subject

Has Abstract

pub_date

1980-05-01 00:00:00

pages

260-6

issue

3

eissn

0020-9996

issn

1536-0210

journal_volume

15

pub_type

杂志文章
  • Short-term effects of a new intravascular nitinol stent in canine arteries.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the short-term effects of a new nitinol stent on canine arteries. METHODS:Eighteen nitinol mesh stents were placed in abdominal aortas, common iliac arteries, and renal arteries of six dogs. Angiography was performed to evaluate the patency rates and structural changes of arteries ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199905000-00007

    authors: Lee KW,Park JH,Chung JW,Kim WS,Lee W,Yeon KM

    更新日期:1999-05-01 00:00:00

  • Subtype differentiation of renal tumors using voxel-based histogram analysis of intravoxel incoherent motion parameters.

    abstract:OBJECTIVES:The aim of this study was to determine if voxel-based histogram analysis of intravoxel incoherent motion imaging (IVIM) parameters can differentiate various subtypes of renal tumors, including benign and malignant lesions. SUBJECTS AND METHODS:A total of 44 patients with renal tumors who underwent surgery a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000111

    authors: Gaing B,Sigmund EE,Huang WC,Babb JS,Parikh NS,Stoffel D,Chandarana H

    更新日期:2015-03-01 00:00:00

  • Phantom testing of peripheral artery. Absolute blood flow measurement with digital arteriography.

    abstract::A technique to measure absolute arterial blood flow in ml/min has been developed utilizing software programs with high-speed digital recording for the off-line analysis of intra-arterial injections of contrast medium. Measurements of pulsatile flow in a phantom for a physical flow model showed that calculations with t...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198503000-00017

    authors: Forbes G,Gray JE,Felmlee JP

    更新日期:1985-03-01 00:00:00

  • Degenerative disease of the sacroiliac joint.

    abstract::Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac oste...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197511000-00008

    authors: Resnick D,Niwayama G,Goergen TG

    更新日期:1975-11-01 00:00:00

  • Air-filled ultrasound contrast agents do not damage the cerebral microvasculature or brain tissue in rats.

    abstract:RATIONALE AND OBJECTIVES:Air microemboli may damage the cerebral microvasculature. The aim of this study was to evaluate the safety of ultrasound contrast agents composed of air microspheres with regard to cerebral damage when administered into the arterial system (ie, when not filtered by the capillary system of the l...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199803000-00001

    authors: Haggag KJ,Russell D,Walday P,Skiphamn A,Torvik A

    更新日期:1998-03-01 00:00:00

  • Educational objectives for diagnostic radiology residency training.

    abstract::A method of teaching radiology residents by identification of general and specific objectives to be accomplished during each time segment of the four-year training program has been developed. The objectives are incorporated into an educational contract that is signed by the resident and rotation director at the beginn...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198612000-00009

    authors: Howland WJ,Marler D,Bosshart D

    更新日期:1986-12-01 00:00:00

  • Identifying tumor vascular permeability heterogeneity with magnetic resonance imaging contrast agents.

    abstract:RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200204000-00003

    authors: Aref M,Brechbiel M,Wiener EC

    更新日期:2002-04-01 00:00:00

  • Observer variation in detecting the radiologic features associated with bronchiolitis.

    abstract::Chest radiographs are commonly obtained to assess children for bronchiolitis, both to corroborate the diagnosis and to exclude other diagnostic possibilities. Their utility in this setting has not previously been examined. Using a blinded, randomized study design, we examined the interobserver and intraobserver variat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199102000-00004

    authors: Coblentz CL,Babcook CJ,Alton D,Riley BJ,Norman G

    更新日期:1991-02-01 00:00:00

  • Application of direct cannulation and injection lymphangiography to the study of the canine cardiac and pulmonary efferent mediastinal lymphatics.

    abstract::Lymphangiograms of canine cardiac and pulmonary efferent mediastinal lymphatics were made by cannulation and injection of Ethiodol. Injections were made singly and serially. The mediastinal lymphatics and lymph nodes, which constitute the pathways of drainage of the heart and lungs, were delineated from the point of c...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197901000-00012

    authors: Leeds SE,Uhley HN,Meister RB

    更新日期:1979-01-01 00:00:00

  • Response of tumors to therapy studied by 31P magnetic resonance spectroscopy.

    abstract::Magnetic resonance (MR) methods have been used to study the metabolic and vascular response of model tumors to tumor necrosis factor (TNF). Magnetic resonance measurements demonstrated acute reductions in tumor blood flow, measured from tumor uptake of D2O, and in tumor adenosine triphosphate (ATP), measured by 31P ma...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198912000-00022

    authors: Karczmar GS,Meyerhoff DJ,Speder A,Valone F,Wilkinson M,Shine N,Boska MD,Weiner MW

    更新日期:1989-12-01 00:00:00

  • Investigation of 125I as an isotopic source for mammography.

    abstract::An isotopic radiation source 125I was investigated for use in soft tissue radiaography, with particular attention to possible use in mammography for mass screening. Film sensitivities, exposure rates, absorbed doeses, contrast and resolution were determined, and compared to conventional x-ray units. It was found that ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197509000-00007

    authors: Fairchild R,Atkins HL,Lebowitz E,Greenberg D

    更新日期:1975-09-01 00:00:00

  • Interleaved Mapping of Temperature and Longitudinal Relaxation Rate to Monitor Drug Delivery During Magnetic Resonance-Guided High-Intensity Focused Ultrasound-Induced Hyperthermia.

    abstract:OBJECTIVES:Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41°C-43°C) in deep-seated tissues. Magnetic Resonance (MR) imaging provides therapy planning on anatomical i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000392

    authors: Kneepkens E,Heijman E,Keupp J,Weiss S,Nicolay K,Grüll H

    更新日期:2017-10-01 00:00:00

  • High-Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted Images: Evaluation of the Macrocyclic Gadolinium-Based Contrast Agent Gadobutrol.

    abstract:OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000227

    authors: Radbruch A,Weberling LD,Kieslich PJ,Hepp J,Kickingereder P,Wick W,Schlemmer HP,Bendszus M

    更新日期:2015-12-01 00:00:00

  • Digital radiography versus conventional radiography for the detection of a skull fracture under varying exposure parameters.

    abstract:RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199303000-00010

    authors: Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

    更新日期:1993-03-01 00:00:00

  • The mini-fellowship in teaching. A senior resident elective.

    abstract::The residency program at the University of Pennsylvania offers a 1-month fellowship for senior residents in medical student education. Instructional philosophy, methods, and content are discussed, observed, practiced, and evaluated. Close supervision and immediate feedback provide training particularly needed by futur...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199006000-00028

    authors: Troupin RH

    更新日期:1990-06-01 00:00:00

  • The biliary and urinary excretion of sodium tyropanoate and sodium ipodate in dogs: pharmacokinetics, influence of bile salts and choleretic effects with comparison to iopanoic acid.

    abstract::The biliary and urinary excretion of sodium tyropanoate (Bilopaque) and sodium ipodate (Oragrafin) were studied in unanesthetized bile-fistula dogs using stepwise, increasing, intravenous infusions of the contrast materials. A constant intravenous infusion of sodium taurocholate was administered at the rate of either ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197701000-00017

    authors: Berk RN,Loeb PM,Cobo-Frenkel A,Barnhart JL

    更新日期:1977-01-01 00:00:00

  • Ultrasonic echoes registered from erythrocytes.

    abstract::Erythrocytes at various concentrations were examined with a sensitive A-mode ultrasonic scanner; simultaneous measurements were made under light microscopic control. Individual erythrocytes caused weak (about 1 dB) echoes while erythrocyte aggregates (ten to 100 cells) produced stronger echoes (up to 15 dB), grossly p...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198508000-00014

    authors: Alanen A,Kormano M

    更新日期:1985-08-01 00:00:00

  • The radiation dosimetry and normal value study of 99mTc-HMPAO-labeled leukocytes.

    abstract:RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 9...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199404000-00010

    authors: Brown ML,Hung JC,Vetter RJ,O'Connor MK,Chowdhury S,Forstrom LA

    更新日期:1994-04-01 00:00:00

  • Evaluation of complex joint motion with computer-based analysis of fluoroscopic sequences.

    abstract:RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200202000-00004

    authors: Pfirrmann CW,Huser M,Székely G,Hodler J,Gerber C

    更新日期:2002-02-01 00:00:00

  • The clotting issue: etiologic factors in thromboembolism. II. Clinical considerations.

    abstract:RATIONALE AND OBJECTIVES:The authors analyze the origins of the "clotting issue," the controversy that began in the 1980s when contrast media, once perceived as good flushing agents for catheters because of their assumed anticoagulant properties, came under attack for allegedly causing thromboembolism. Laboratory studi...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:

    authors: Dawson P,Cousins C,Bradshaw A

    更新日期:1993-11-01 00:00:00

  • Human brain chemical shift imaging at age 60 to 90: analysis of the causes of the observed sex differences in brain metabolites.

    abstract:RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200110000-00005

    authors: Sijens PE,Den Heijer T,De Leeuw FE,De Groot JC,Achten E,Heijboer RJ,Hofman A,Breteler MM,Oudkerk M

    更新日期:2001-10-01 00:00:00

  • Free-breathing three-dimensional computed tomography of the lung using prospective respiratory gating: charge-coupled device camera and laser sensor device in an animal experiment.

    abstract:PURPOSE:The aim was to investigate the feasibility and image quality of prospective respiratory gating for 3-D computed tomography (CT) of the lung. MATERIAL AND METHODS:Eight anesthetized pigs underwent prospectively gated multidetector computed tomography using 2 devices: a charge-coupled device (CCD) camera and a l...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000208926.98693.b6

    authors: Zaporozhan J,Ley S,Unterhinninghofen R,Saito Y,Fabel-Schulte M,Keller S,Szabo G,Kauczor HU

    更新日期:2006-05-01 00:00:00

  • Influence of soft tissue (fat and fat-free mass) on ultrasound bone velocity: an in vivo study.

    abstract:RATIONALE AND OBJECTIVES:The authors determine the relative effect of soft-tissue compartments, body fat (percent [%Bfat] and weight [Bfat kg]) and fat-free mass (FFM kg), on measurements of ultrasound bone velocity (UBV m/second). METHODS:The authors measured UBV in proximal phalanxes and body fat and fat-free mass b...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199710000-00005

    authors: Gómez M,Aguado F,Manuel J,Menéndez JM,Revilla M,Villa LF,Cortés J,Rico H

    更新日期:1997-10-01 00:00:00

  • Biodistribution of radiolabeled, formulated gadopentetate, gadoteridol, gadoterate, and gadodiamide in mice and rats.

    abstract:RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199506000-00008

    authors: Tweedle MF,Wedeking P,Kumar K

    更新日期:1995-06-01 00:00:00

  • Cerebral computed tomography angiography using a low tube voltage (80 kVp) and a moderate concentration of iodine contrast material: a quantitative and qualitative comparison with conventional computed tomography angiography.

    abstract:OBJECTIVE:To investigate the feasibility of an 80-kVp protocol using a moderate concentration contrast material (MC-CM) for cerebral computed tomography angiography by comparison with a conventional 120-kVp protocol using a high concentration contrast material (HC-CM). MATERIALS AND METHODS:Attenuation values and sign...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31823076a4

    authors: Cho ES,Chung TS,Oh DK,Choi HS,Suh SH,Lee HK,Lee KH

    更新日期:2012-02-01 00:00:00

  • Pediatric Brain: Gadolinium Deposition in Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted Images Is Dependent on the Type of Contrast Agent.

    abstract:PURPOSE:The aim of this study was to identify the signal intensity (SI) changes in the dentate nucleus (DN) and the globus pallidus (GP) on unenhanced T1-weighted magnetic resonance (MR) images after multiple administration of gadolinium-based contrast agents (GBCAs) in children and compare those changes between linear...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000436

    authors: Ryu YJ,Choi YH,Cheon JE,Lee WJ,Park S,Park JE,Kim WS,Kim IO

    更新日期:2018-04-01 00:00:00

  • Granulocyte accumulation in the transplanted liver does not correlate with clinical and histologic evidence of dysfunction.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the role of granulocytes in reperfusion injury after liver transplantation. The authors injected radiolabeled granulocytes to determine if human liver graft outcome could be correlated with granulocyte accumulation. MATERIALS AND METHODS:Pure granulocyte suspension was prepared fro...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199603000-00003

    authors: Ziser A,Forstrom LA,Plevak DJ,Sanchez-Urdazpal L,Gores GJ,Wiesner RH,Batts KP,Krom RA

    更新日期:1996-03-01 00:00:00

  • Pulmonary density distribution in experimental noncardiac canine pulmonary edema evaluated by computed transmission tomography.

    abstract::We evaluated the density distribution (anterior-posterior) of the right lung in 19 acutely anesthetized supine dogs using computed transmission tomography (CTT). Eleven dogs served as controls, and eight received 0.12 cc/kg of intravenously administered oleic acid. The latter were sequentially imaged over 1 hour. Nine...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:

    authors: Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

    更新日期:1984-05-01 00:00:00

  • The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation, and vascularization.

    abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199306000-00011

    authors: Ni Y,Marchal G,Zhang X,Van Hecke P,Michiels J,Yu J,Rummeny E,Lodemann KP,Baert AL

    更新日期:1993-06-01 00:00:00

  • The effect of verification on the assessment of imaging techniques.

    abstract::In order to measure the accuracy of a diagnostic imaging technique, the correctness of each observer decision must be determined. This is often difficult in clinical cases, and various strategies are frequently used to approximate the truth. Experiments using chest radiographs as an example are reported to show the pi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198303000-00018

    authors: Revesz G,Kundel HL,Bonitatibus M

    更新日期:1983-03-01 00:00:00