Short-term effects of a new intravascular nitinol stent in canine arteries.

Abstract:

RATIONALE AND OBJECTIVES:To evaluate the short-term effects of a new nitinol stent on canine arteries. METHODS:Eighteen nitinol mesh stents were placed in abdominal aortas, common iliac arteries, and renal arteries of six dogs. Angiography was performed to evaluate the patency rates and structural changes of arteries at 1 day, 3 weeks, 4 weeks, and 10 weeks after stent insertion. Gross and light microscopic examinations were performed after angiography. RESULTS:On angiography, the patency rate was 100%, and no thrombosis was observed. All side branches from stented segments were patent. The mean neointimal thickness over and between stent wires was 94 and 167 microns. No difference was found between the aorta and the small vessels. Histologically, the neointima was covered with endothelium and was composed of subintimal fibrosis with mild inflammation. CONCLUSIONS:The new type of nitinol mesh stent showed a high patency rate, with no thrombosis and relatively thin neointimal proliferation.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Lee KW,Park JH,Chung JW,Kim WS,Lee W,Yeon KM

doi

10.1097/00004424-199905000-00007

keywords:

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

367-73

issue

5

eissn

0020-9996

issn

1536-0210

journal_volume

34

pub_type

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