Saturation kinetics of iopanoate in dogs with an intact enterohepatic circulation. Before and after phenobarbital induction.

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...

journal_title：Investigative radiology

authors： Hellbach K,Yaroshenko A,Willer K,Pritzke T,Baumann A,Hesse N,Auweter S,Reiser MF,Eickelberg O,Pfeiffer F,Hilgendorff A,Meinel FG

更新日期：2016-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To improve the accuracy of magnetic resonance imaging (MRI) in evaluating the response of osteosarcomas to preoperative chemotherapy, the authors developed a technique of mapping tumor necrosis and viability by quantitating slope values of gadolinium-DTPA (Gd-DTPA) uptake on dynamic fast low-an...

journal_title：Investigative radiology

authors： Hanna SL,Parham DM,Fairclough DL,Meyer WH,Le AH,Fletcher BD

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of combining inner-volume imaging (IVI) techniques with conventional multishot periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) techniques for targeted-PROPELLER magnetic resonance imaging. MATERIALS AND METHODS:Perpendicular section-selective ...

journal_title：Investigative radiology

authors： Deng J,Larson AC

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the feasibility of the combination of magnetic resonance (MR)-guided biopsy (MRGB) and diagnostic 3T MR imaging in the localization of local recurrence of prostate cancer (PCa) after external beam radiation therapy (EBRT). MATERIALS AND METHODS:Twenty-four consecuti...

journal_title：Investigative radiology

authors： Yakar D,Hambrock T,Huisman H,Hulsbergen-van de Kaa CA,van Lin E,Vergunst H,Hoeks CM,van Oort IM,Witjes JA,Barentsz JO,Fütterer JJ

更新日期：2010-03-01 00:00:00

abstract：:We compared the damage resulting from intradermal injection of four commonly used radiographic contrast media in laboratory rats. Sixty percent meglumine diatrizoate (Reno M 60) and ioxaglate (Hexabrix) produced significantly more ulceration and crusting on gross inspection and more necrosis, edema, and hemorrhage on ...

journal_title：Investigative radiology

authors： Cohan RH,Leder RA,Bolick D,Herzberg AJ,Hedlund LW,Wheeler CT,Helms MJ,Dunnick NR

更新日期：1990-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To test noninvasive inductive heating of implanted vascular stents as an alternative approach for reduction or prevention of neointimal hyperplasia. METHODS:Calorimetric pretests were performed to get an orientation on the different parameters of influence for inductive heating of stents. The ...

journal_title：Investigative radiology

authors： Floren MG,Günther RW,Schmitz-Rode T

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:In late December 2019, an outbreak of coronavirus disease (COVID-19) in Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory syndrome coronavirus 2. We aimed to quantify the severity of COVID-19 infection on high-resolution chest computed tomography (CT) and to determine its r...

journal_title：Investigative radiology

authors： Xiong Y,Sun D,Liu Y,Fan Y,Zhao L,Li X,Zhu W

更新日期：2020-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new animal model for the evaluation of the renal tolerance of contrast agent and its application to diatrizoate and iotrolan injections in comparison to saline and mannitol solution. MATERIALS AND METHODS:The nephrotoxic potential of intravenously injected contrast agents in Beagl...

journal_title：Investigative radiology

authors： Krause W,Gilles T

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate accuracy of biliary anatomy depiction and quality of biliary tract visualization of magnetic resonance cholangiography (MRC) at 3.0 T in living potential liver donors (LPLDs). MATERIALS AND METHODS:Our institutional review board approved this study and did not require patient's inf...

journal_title：Investigative radiology

authors： Kim SY,Byun JH,Hong HS,Choi EK,Lee SS,Park SH,Lee MG

更新日期：2008-08-01 00:00:00

abstract：:A technique to measure absolute arterial blood flow in ml/min has been developed utilizing software programs with high-speed digital recording for the off-line analysis of intra-arterial injections of contrast medium. Measurements of pulsatile flow in a phantom for a physical flow model showed that calculations with t...

journal_title：Investigative radiology

authors： Forbes G,Gray JE,Felmlee JP

更新日期：1985-03-01 00:00:00

abstract：:We examined the acute systemic and renal hemodynamic effects of intravenous meglumine/sodium diatrizoate-76% and iopamidol in euvolemic and dehydrated dogs. The physiologic responses were compared with acute changes in the level of an endogenous heparin-like material (EHM). One of eight dehydrated dogs receiving diatr...

journal_title：Investigative radiology

authors： Katzberg RW,Morris TW,Lasser EC,DiMarco PL,Merguerian PA,Ventura JA,Pabico RC,McKenna BA

更新日期：1986-10-01 00:00:00

abstract：PURPOSE:To determine the reproducibility, accuracy, and predictors of accuracy of computed tomography (CT) angiography to detect and characterize coronary atherosclerotic plaque as compared with intravascular ultrasound. METHODS:Ten ex vivo human coronary arteries were imaged in a moving phantom by dual-source CT (col...

journal_title：Investigative radiology

authors： van der Giessen AG,Toepker MH,Donelly PM,Bamberg F,Schlett CL,Raffle C,Irlbeck T,Lee H,van Walsum T,Maurovich-Horvat P,Gijsen FJ,Wentzel JJ,Hoffmann U

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:We sought to assess large bowel motility, induced by 2 prokinetic agents, senna tea and erythromycin, using functional cine magnetic resonance imaging (MRI). MATERIALS AND METHODS:Twelve volunteers underwent functional cine MRI before and after the administration of senna tea or erythromycin. The protocol c...

journal_title：Investigative radiology

authors： Buhmann S,Kirchhoff C,Wielage C,Mussack T,Reiser MF,Lienemann A

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the ability of a flow-sensitive alternating inversion recovery-arterial spin labeling (FAIR-ASL) technique to track renal perfusion changes during pharmacologic and physiologic alterations in renal blood flow using microspheres as a gold standard. MATERIALS AND METHODS...

journal_title：Investigative radiology

authors： Artz NS,Wentland AL,Sadowski EA,Djamali A,Grist TM,Seo S,Fain SB

更新日期：2011-02-01 00:00:00

abstract：AIM:: We sought to improve the clinical interpretation of first-pass myocardial magnetic resonance perfusion. Parametric analyses of the myocardial distribution of the contrast agent have been proposed. The objective of the present study was to compare the effectiveness of visual analysis and of a parametric approach i...

journal_title：Investigative radiology

authors： Carme S,Maï W,Mazzadi A,Janier M,Revel D,Magnin I,Wiart M,Neyran B,Canet-Soulas E

更新日期：2006-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...

journal_title：Investigative radiology

authors： Schürmann K,Vorwerk D,Kulisch A,Stroehmer-Kulisch E,Biesterfeld S,Stopinski T,Günther RW

更新日期：1995-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors compare the magnetic resonance (MR) phase contrast flow velocity measurements in varying concentric stenoses with invasive measurements obtained with a Doppler guidewire. METHODS:Flow velocity measurements were obtained using a calibrated 0.018 inch 12 MHz Doppler guidewire and a 1...

journal_title：Investigative radiology

authors： Hoppe M,Heverhagen JT,Froelich JJ,Kunisch-Hoppe M,Klose KJ,Wagner HJ

更新日期：1998-08-01 00:00:00

abstract：:The microangiographic anatomy of the cat's eye is presented. The characteristic vascular pattern of each of the three distinct circulations, retinal choroidal, and ciliary is described and illustrated. ...

journal_title：Investigative radiology

authors： Rothman SL,Kier EL,Deuker DK

更新日期：1975-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Laser-induced interstitial thermotherapy (LITT) may become an attractive modality for minimally invasive tumor therapy. Magnetic resonance imaging (MRI) could be used to assist this procedure. METHODS:A T1-weighted turbo fast low-angle shot (FLASH) sequence for on-line monitoring of the laser-...

journal_title：Investigative radiology

authors： Gewiese B,Beuthan J,Fobbe F,Stiller D,Müller G,Böse-Landgraf J,Wolf KJ,Deimling M

更新日期：1994-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the safety and pharmacokinetics of a newly developed MR contrast medium consisting of very small superparamagnetic iron oxide particles (VSOP) coated with citrate (VSOP-C184) in a clinical phase I trial. METHODS:A total of 18 healthy subjects received either VSOP-C184 (core diamete...

journal_title：Investigative radiology

authors： Taupitz M,Wagner S,Schnorr J,Kravec I,Pilgrimm H,Bergmann-Fritsch H,Hamm B

更新日期：2004-07-01 00:00:00

abstract：:French physicians must obtain their patient's consent before carrying out an action that interferes with the patient's corporal integrity. The doctor must use simple, approximate, intelligent, and honest words that help the patient to reach the indispensable decision. Proof of lack of consent lies with the patient. Th...

journal_title：Investigative radiology

authors： Alméras JP,Husson R,Moreau JF

更新日期：1988-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...

journal_title：Investigative radiology

authors： Oudkerk M,Sijens PE,Van Beek EJ,Kuijpers TJ

更新日期：1995-02-01 00:00:00

abstract：:Gelatin encapsulated nitrogen microbubbles were effective ultrasonic contrast agents in in vitro phantom and in vivo rabbit V2 carcinoma studies. Intra-arterial injection of 80-micrometer gelatin encapsulated nitrogen microbubbles appeared to improve tumor visualization by rim enhancement, which persisted for several ...

journal_title：Investigative radiology

authors： Carroll BA,Turner RJ,Tickner EG,Boyle DB,Young SW

更新日期：1980-05-01 00:00:00

abstract：:The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...

journal_title：Investigative radiology

authors： Mironidou M,Ximitidou O,Christopoulos S,Kokkas B

更新日期：1998-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:At many institutions, three-dimensional magnetic resonance imaging (MRI) is routinely used for examination of the knee. Multiplanar reconstruction (MPR) is a method of displaying three-dimensional datasets. The authors assessed the usefulness of MPR for evaluating knee MRI datasets by comparing...

journal_title：Investigative radiology

authors： Gay SB,Chen NC,Burch JJ,Gleason TR,Sagman AM

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:We compared the image quality and diagnostic performance of 2 fat-suppression methods for black-blood T2-weighted fast spin-echo (FSE), which are as follows: (a) short T1 inversion recovery (STIR; FSE-STIR) and (b) spectral adiabatic inversion recovery (SPAIR; FSE-SPAIR), for detection of acute myocardial in...

journal_title：Investigative radiology

authors： Srichai MB,Lim RP,Lath N,Babb J,Axel L,Kim D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Though functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examine...

journal_title：Investigative radiology

authors： Barfett JJ,Fierstra J,Mikulis DJ,Krings T

更新日期：2010-12-01 00:00:00

abstract：:The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...

journal_title：Investigative radiology

authors： Cox GG,Templeton AW,Anderson WH,Cook LT,Hensley KS,Dwyer SJ 3rd

更新日期：1986-02-01 00:00:00

abstract：:Left ventricular volume has been measured with ultrafast computed tomography. However, the accuracy with which this can be done is unknown. We therefore imaged with ultrafast computed tomography 11 rectangular phantoms, 20 to 225 ml, and 17 left ventricular casts, 15 to 112 ml. Two observers planimetered serial tomogr...

journal_title：Investigative radiology

authors： Pietras RJ,Wolfkiel CJ,Veselik K,Roig E,Chomka EV,Brundage BH

更新日期：1991-01-01 00:00:00