Experimental arterial stent placement. Comparison of a new Nitinol stent and Wallstent.

Abstract:

RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. Examination of histologic specimen by light microscopy was performed to determine neointimal and medial thickness inside the stents. Measurements were analyzed statistically. RESULTS:Neointima was thicker in Nitinol stents (N) than in Wallstents (W) (P < 0.004), both adjacent to (W = 0.265 mm, N = 0.596 mm) and between the stent wires (W = 0.177 mm, N = 0.361 mm). Because of poor radiopacity and the Crochê releasing technique, delivery was more difficult with Nitinol stents. High-grade stenosis was found in two Nitinol stents at 1 and 4.5 months of follow-up, respectively. One Wallstent was insufficiently incorporated into the vessel wall. CONCLUSIONS:The observed difference in neointima formation that may be caused by differences in design, mechanical properties or the metal alloy of the stents probably is too insignificant to be relevant to patency of large arteries. However, it may be relevant in small vessels such as coronary arteries.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Schürmann K,Vorwerk D,Kulisch A,Stroehmer-Kulisch E,Biesterfeld S,Stopinski T,Günther RW

doi

10.1097/00004424-199507000-00004

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

412-20

issue

7

eissn

0020-9996

issn

1536-0210

journal_volume

30

pub_type

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