Abstract:
:A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours before CM challenge), a double dose (32 mg approximately 12 hours and 2 hours before CM challenge), or placebo. All contrast injections were with ionic media and were given intravenously. The two-dose (but not the one-dose) corticosteroid regimen provided significant protection. The effect on reaction incidences of a number of historical variables is also tabulated.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Lasser EC,Berry CC,Talner LB,Santini LC,Lang EK,Gerber FH,Stolberg HOdoi
10.1097/00004424-198809001-00035subject
Has Abstractpub_date
1988-09-01 00:00:00pages
S193-4eissn
0020-9996issn
1536-0210journal_volume
23 Suppl 1pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract:RATIONALE AND OBJECTIVES:To develop a simple and robust helium3 polarization system dedicated to small animal imaging. To demonstrate the potential of helium3 imaging for pulmonary ventilation and perfusion studies. METHODS:A home-built polarization system based on spin-exchange technique was used. This system was app...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the study was to determine optimal thresholds for semiquantitative perfusion parameters and to evaluate the influence of different segmentation models in detecting malperfused regions. MATERIAL AND METHODS:In 6 healthy subjects and 13 patients with coronary artery disease, contrast-...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000133816.83192.38
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the feasibility of a computed tomography (CT) protocol enabling the visualization of the prostatic artery (PA) before prostatic artery embolization (PAE) in benign prostatic hyperplasia, which provides quantitative perfusion information of the prostate gland. MATERIALS ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000582
更新日期:2019-10-01 00:00:00
abstract::The sonographic appearance of kidneys in patients presenting with acute renal failure due to hemolytic-uremic syndrome (HUS) was evaluated and compared with that in an age-matched control series. In nine patients with HUS, the renal cortex was typically hyperechogenic and the renal pyramids appeared sonolucent. The re...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198607000-00006
更新日期:1986-07-01 00:00:00
abstract::Attenuation correction (AC) is an essential step in the positron emission tomography (PET) data reconstruction process to provide accurate and quantitative PET images. The introduction of PET/magnetic resonance (MR) hybrid systems has raised new challenges but also possibilities regarding PET AC. While in PET/computed...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/RLI.0000000000000289
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:The relaxivities of 3 macrocyclic gadolinium-based contrast agents (GBCAs) were determined in human plasma and blood under standardized and clinically relevant laboratory conditions. METHODS:The T1 relaxivity, r1, was determined in human plasma at 1.5, 3, and 7 T, and in human blood at 3 T at 37°C in phantoms ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000577
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the gadolinium (Gd) concentration remaining in human bone tissue after administration of standard clinical doses of 2 Gd-based contrast agents: ProHance and Omniscan. MATERIALS AND METHODS:After administration of 0.1 mmol/kg of Gd chelate to patients undergoing hi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000186569.32408.95
更新日期:2006-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Tissue contrast phenomenology was investigated analytically and clinically for a class of magnetic resonance (MR) pulse sequences we call large-tip-angle (LTA) spin-echo (SE) imaging. In comparison to traditional SE sequences (denoted 90 degrees-180 degrees-echo), the LTA sequence is of the for...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199310000-00017
更新日期:1993-10-01 00:00:00
abstract::Electromagnetic flow measurement study was performed in 20 anesthetized dogs to evaluate the effect of selective celiac infusion of vasopressin on the hepatic arterial vasculature. Teh hepatic arterial flow showed a biphasic response with an initial decrease followed by a substantial increase in spite of a continued ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1975-05-01 00:00:00
abstract::Methods are presented for the quantification of spatial resolution in x-ray computed tomographic (CT) images. Model-dependent methods are derived and compared with model independent methods for computation of the Modulation Transfer Function (MTF). These techniques are applied to phantom images of point, line, edge, a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198603000-00012
更新日期:1986-03-01 00:00:00
abstract:RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199402000-00007
更新日期:1994-02-01 00:00:00
abstract::Left ventricular volume has been measured with ultrafast computed tomography. However, the accuracy with which this can be done is unknown. We therefore imaged with ultrafast computed tomography 11 rectangular phantoms, 20 to 225 ml, and 17 left ventricular casts, 15 to 112 ml. Two observers planimetered serial tomogr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199101000-00006
更新日期:1991-01-01 00:00:00
abstract::Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198209000-00009
更新日期:1982-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199506000-00008
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:Transcatheter arterial embolization (TAE) is used for the treatment of patients with malignant liver tumors. However, the proangiogenesis effect of TAE-associated hypoxia has not been adequately studied. The goal of this study was to determine angiogenic activity in tumors subjected to TAE by evaluating the ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000209663.00629.8a
更新日期:2006-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We investigated whether it is possible to investigate degenerative changes in human tissue on a sub-100-microm resolution scale not only on special high-field small-bore MR-microscopy systems but also on a 3T whole-body MR-scanner. METHODS:Spin-spin relaxation, proton density, and diffusion mi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000068620.17569.83
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000163743.63063.9f
更新日期:2005-06-01 00:00:00
abstract::Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198902000-00005
更新日期:1989-02-01 00:00:00
abstract::The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198707000-00004
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the feasibility of nonenhanced magnetic resonance angiography (MRA) of the lower extremities at 7 tesla (T). MATERIALS AND METHODS:Eight healthy volunteers were examined on a 7-T whole-body magnetic resonance system. For image acquisition, a custom-built 16-channel t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182839c2b
更新日期:2013-07-01 00:00:00
abstract::Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199111000-00008
更新日期:1991-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors studied the effect of contrast dose, use of magnetization transfer (MT), and temporal delay on the visualization of contrast enhancement with gadoteridol (Gd HP-DO3A) in a canine brain abscess model. METHODS:Alpha streptococcus brain abscesses were studied in five dogs at 1.5 tesla...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199503000-00001
更新日期:1995-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare the visibility and localization of extratemporal cortical lesions in extratemporal epilepsy by using curved reconstruction (CR) and three-dimensional surface rendering (3D SR) of 3D-acquired MR images and to study the degree of confidence with which localizations are made, particular...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200104000-00005
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the feasibility of kidney stone composition analysis using spectral detector computed tomography scanner (SDCT) with normal- and low-dose imaging protocols. METHODS:A total of 154 stones harvested from nephrolithotripsy or nephrolithotomy with a known monocrystalline...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000468
更新日期:2018-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors differentiate acute tubular necrosis from transplant rejection in patients with delayed kidney graft function using gadolinium (Gd)-DTPA enhanced magnetic resonance (MR) imaging. METHODS:Twenty-four patients after renal transplantation (10 with normal graft function, 14 with delaye...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/00004424-199606000-00009
更新日期:1996-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000116125.96544.64
更新日期:2004-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Echogenic antibody-conjugated anionic liposomes have been developed that allow directed tissue targeting and acoustic enhancement. These are not efficient for gene delivery. A cationic formulation that allows directed gene delivery while retaining acoustic properties may provide more efficient ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200012000-00007
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVES:The aim of this work was to quantitatively evaluate the pharmacokinetic pattern of Gd-EOB-DTPA in a model of isolated and perfused mouse liver by using magnetic resonance imaging (MRI) and monochromatic quantitative computed tomography (MQCT). MATERIALS AND METHODS:For MQCT, perfusions were realized with th...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000174474.43772.58
更新日期:2005-09-01 00:00:00
abstract::Previous investigations in this laboratory have confirmed the observation of facial muscle twitching during intracarotid injections of nonionic contrast media (CM) in rabbits. The reaction appears to be a locally mediated effect. To further investigate this reaction, cortical electroencephalogram (EEG) and facial elec...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199009000-00010
更新日期:1990-09-01 00:00:00
abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198908000-00007
更新日期:1989-08-01 00:00:00