Microcomputer-based technique for 3-D reconstruction and volume measurement of computer tomographic images. Part 1: Phantom studies.


:This paper presents a microcomputer-based technique that accurately quantifies volumes from computed tomographic (CT) scans of irregularly shaped objects as well as displaying 3-D reconstructions. The method uses standard CT film, allowing analysis of previous or outside CT studies. The planimetry method showed less than 5% error in measuring irregular 2-D areas larger than 6 mm2. The method is demonstrated to be significantly more accurate than spherical, ellipsoid, or rectangular geometric models in quantifying object volume by CT (P less than .001). With a single gantry angle, planimetry showed a two standard deviation error under 10% in measuring the volume of irregular objects compared with an error over 30% for ellipsoid models. The inaccuracy of the spherical model (80% error) and the rectangular prism model (192% error) renders them impractical to provide quantitative object volume. Microcomputer planimetry provides an accurate and versatile means to measure the volume and produce 3-D reconstructions of objects scanned with CT, and it has potential application in quantifying tumor response with CT and magnetic resonance imaging.


Invest Radiol


Investigative radiology


Albright RE Jr,Fram EK




Has Abstract


1988-12-01 00:00:00












  • The potential of iosulamide meglumine as a contrast material for intravenous cholangiography: an experimental study in dogs.

    abstract::Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Berk RN,Barnhart JL,Nazareno G,Witt BL

    更新日期:1981-05-01 00:00:00

  • Vein graft-coated stents for endovascular occlusion of canine experimental arteriovenous fistulae.

    abstract:RATIONALE AND OBJECTIVES:To evaluate different vein graft-coated stent systems in the endovascular treatment of experimental arteriovenous fistulae (AVF) in a canine model. METHODS:Bilateral carotid-to-external jugular vein AVF were created. Two balloon-expandable tantalum stents (Strecker stent), two self-expanding n...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Schellhammer F,Wahkloo AK,Nagursky H,Schumacher M

    更新日期:1999-01-01 00:00:00

  • Role of red blood cell deformation in toxicity of contrast media in cerebral angiography.

    abstract::The authors investigated the effect on the brain of red blood cells that had been modified by contrast media. Rat blood was mixed with an equivolume of contrast media, and up to 200 microL of the mixture was infused to the internal carotid artery of the rat. Evans blue was administered intravenously to assess the inte...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Miyazawa T,Nakagawa H,Oshino N

    更新日期:1989-05-01 00:00:00

  • Intravoxel incoherent motion diffusion-weighted imaging of pancreatic neuroendocrine tumors: prediction of the histologic grade using pure diffusion coefficient and tumor size.

    abstract:PURPOSE:The purpose of this study was to assess the value of intravoxel incoherent motion and diffusion-weighted imaging for predicting the histologic grade of pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:Forty patients with surgically diagnosed PNETs who underwent preoperative magnetic resonance im...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Hwang EJ,Lee JM,Yoon JH,Kim JH,Han JK,Choi BI,Lee KB,Jang JY,Kim SW,Nickel MD,Kiefer B

    更新日期:2014-06-01 00:00:00

  • Dual source dual energy MDCT: comparison of 80 kVp and weighted average 120 kVp data for conspicuity of hypo-vascular liver metastases.

    abstract:PURPOSE:To determine whether liver metastases conspicuity is improved at 80 kVp when compared with weighted average (WA) simulated 120 kVp data using dual source dual energy CT. METHODS:A total of 11 patients with 44 hypo-vascular liver metastases underwent contrast enhanced Dual Energy CT (DECT). In all cases the sub...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Robinson E,Babb J,Chandarana H,Macari M

    更新日期:2010-07-01 00:00:00

  • Radioimmunodetection of a transplantable human bladder carcinoma in a nude mouse.

    abstract::The results of an in vitro mixed hemadsorption (MHA) assay predicted the success of in vivo tumor localization using a radioiodinated, monoclonal, IgG1 antibody (A2) with reactivity to the human bladder carcinoma cell line RT4. In vitro, murine monoclonal antibodies A2 and G6, demonstrated reactivity to RT4 with titer...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Gross MD,Skinner RW,Grossman HB

    更新日期:1984-11-01 00:00:00

  • Lung perfusion demonstrated by contrast-enhanced dynamic magnetic resonance imaging. Application to unilateral lung transplantation.

    abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Berthezène Y,Croisille P,Bertocchi M,Houzard C,Bendib K,Revel D

    更新日期:1997-06-01 00:00:00

  • A new class of contrast agents for magnetic resonance imaging based on selective reduction of water-T2 by chemical exchange.

    abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Aime S,Nano R,Grandi M

    更新日期:1988-09-01 00:00:00

  • Hepatic kinetics and magnetic resonance imaging of gadolinium-EOB-DTPA in dogs.

    abstract:RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Benness G,Khangure M,Morris I,Warwick A,Burrows P,Vogler H,Weinmann HJ

    更新日期:1996-04-01 00:00:00

  • Detection of breast abnormalities on teleradiology transmitted mammograms.

    abstract::The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Fajardo LL,Yoshino MT,Seeley GW,Hunt R,Hunter TB,Friedman R,Cardenas D,Boyle R

    更新日期:1990-10-01 00:00:00

  • Computerized case-based instructional system for computed tomography and magnetic resonance imaging of brain tumors.

    abstract:RATIONALE AND OBJECTIVES:A computerized system that applies the case-based approach to training radiologists to diagnose brain tumors was designed. The authors attempted to provide residents a tool that supports their visual memory and inducts case-based reasoning. METHODS:A relational database with a digital image li...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Macura RT,Macura KJ,Toro VE,Binet EF,Trueblood JH,Ji K

    更新日期:1994-04-01 00:00:00

  • Minimal spinal hyperostosis with low-dose isotretinoin therapy.

    abstract::Skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin A and its derivatives. Recently, a new derivative, isotretinoin (Accutane, Hoffman-LaRoche, Inc.), has become available for the treatment of cystic acne. Ninety-six patients treated for a minimum of four...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Kilcoyne RF,Cope R,Cunningham W,Nardella FA,Denman S,Franz TJ,Hanifin J

    更新日期:1986-01-01 00:00:00

  • Continuous Hepatic Arterial Multiphase Magnetic Resonance Imaging During Free-Breathing.

    abstract:PURPOSE:The aim of this study was to evaluate the feasibility of a prototype volume-interpolated breath-hold examination (VIBE) sequence using compressed sensing (VIBECS) for rapid multiphase arterial magnetic resonance imaging (MRI) at different temporal resolution during free-breathing in comparison with a convention...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Weiss J,Notohamiprodjo M,Taron J,Martirosian P,Nickel D,Bamberg F,Nikolaou K,Othman AE

    更新日期:2018-10-01 00:00:00

  • Assessment of cerebral blood flow in man by video dilution technique: a preliminary report.

    abstract::Video dilution technique (VDT) is currently performed in conjunction with routine cerebral angiography to determine carotid blood flow in humans. Preliminary results indicate that the blood flows (as a percentage of cardial output) of the common, internal, and external carotid arteries are 8.5%, 5.5%, and 3.0%, respec...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Lantz BM,Dublin AB,McGahan JP,Link DP

    更新日期:1981-05-01 00:00:00

  • Analysis of edge-tracking errors inherent in fluoroscopic images of the beating heart.

    abstract:RATIONALE AND OBJECTIVES:Because of the complex relationships between the dynamic three-dimensional cardiac surface shape and its projected image, errors arise with the use of two-dimensional silhouettes to measure displacements of the heart. The character and frequency of such errors are examined. METHODS:A high-prec...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: McInerney JJ,Weldner PW,Herr MD,Copenhaver GL

    更新日期:1994-03-01 00:00:00

  • Effect of increasing current and decreasing blood flow for transcatheter electrocoagulation (TCEC).

    abstract::Arterial occlusion by direct-current transcatheter electrocoagulation (TCEC) has been developed experimentally and used successfully in clinical situations. The major shortcoming of the technique has been the lengthy time necessary for occlusion of larger arteries. In the present study we attempted to decrease the tim...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Ralston MD,Woodfield S,Halvorsen R,Pizzo SV,Thompson WM

    更新日期:1982-03-01 00:00:00

  • Comparison of observer performance reading from a video CRT vs. reading from film.

    abstract::The developing trend for all medical images to be in digital form raises an important question: should diagnostic interpretations be made directly from a CRT or from some form of hard copy recording of the CRT? This question was studied by having two observers read a series of digital images of the thyroid including b...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Keyes JW Jr,Kline RC,Resinger WW,Rose EA,Koral KF,Rogers WL

    更新日期:1983-05-01 00:00:00

  • Experimental renal papillary necrosis in rats: microangiographic and tubular micropuncture injection studies.

    abstract::Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Cuttino JT Jr,Goss FU,Clark RL,Marr MC

    更新日期:1981-03-01 00:00:00

  • Comparison of open- and closed-chest canine model for quantification of coronary stenosis severity by myocardial contrast echocardiography.

    abstract:RATIONALE AND OBJECTIVES:The objective of the present study was to compare the data regarding the ability of real-time myocardial contrast echocardiography (MCE) to assess altered myocardial blood flow produced by graded coronary stenoses between open- and closed-chest canine models. MATERIALS AND METHODS:Three grades...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Masugata H,Peters B,Lafitte S,Yao B,Strachan M,Ling Kwan O,Ohmori K,Mizushige K,Kohno M

    更新日期:2003-01-01 00:00:00

  • Blood velocity calculated from volumetric dynamic computed tomography angiography.

    abstract:OBJECTIVE:Though functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examine...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Barfett JJ,Fierstra J,Mikulis DJ,Krings T

    更新日期:2010-12-01 00:00:00

  • Optimal injection protocol for CT evaluation during hepatic arterial infusion chemotherapy.

    abstract:OBJECTIVE:As an imaging modality for follow-up during continuous or repeated hepatic arterial infusion chemotherapy using a hepatic intra-arterial indwelling catheter, the usefulness of CT while infusing contrast through the indwelling catheter (reservoir port) was examined. METHODS:Using reservoir ports implanted in ...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Morimoto M,Satake M,Sekiguchi R,Haruno M,Moriyama N

    更新日期:1999-12-01 00:00:00

  • Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro.

    abstract:RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

    更新日期:1995-10-01 00:00:00

  • A double-blind comparative study of Hexabrix and Renografin-76 in aortography and visceral arteriography.

    abstract::A diatrizoate compound (Renografin-76) and low osmolality Hexabrix were compared in a double-blind study of 50 adults undergoing arteriographic examination. Subjective and objective assessment of pain reaction for each contrast injection rated lower overall for Hexabrix. Discomfort associated with Renografin was great...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章


    authors: Barth KH,Mertens MA

    更新日期:1984-11-01 00:00:00

  • Systolic flow displacement correlates with future ascending aortic growth in patients with bicuspid aortic valves undergoing magnetic resonance surveillance.

    abstract:OBJECTIVES:Altered systolic blood flow in the ascending aorta has been correlated with increased aortic growth in patients with bicuspid aortic valves (BAVs). We used conventional, 2-dimensional (2D) phase contrast magnetic resonance imaging (PC-MRI) to assess the relationship between altered flow and future growth in ...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Burris NS,Sigovan M,Knauer HA,Tseng EE,Saloner D,Hope MD

    更新日期:2014-10-01 00:00:00

  • Spontaneous acute dissection of the internal carotid artery: high-resolution magnetic resonance imaging at 3.0 tesla with a dedicated surface coil.

    abstract:PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Bachmann R,Nassenstein I,Kooijman H,Dittrich R,Kugel H,Niederstadt T,Kuhlenbäumer G,Ringelstein EB,Krämer S,Heindel W

    更新日期:2006-02-01 00:00:00

  • Improved diagnosis of pulmonary emphysema using in vivo dark-field radiography.

    abstract:OBJECTIVES:The purpose of this study was to assess whether the recently developed method of grating-based x-ray dark-field radiography can improve the diagnosis of pulmonary emphysema in vivo. MATERIALS AND METHODS:Pulmonary emphysema was induced in female C57BL/6N mice using endotracheal instillation of porcine pancr...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Meinel FG,Yaroshenko A,Hellbach K,Bech M,Müller M,Velroyen A,Bamberg F,Eickelberg O,Nikolaou K,Reiser MF,Pfeiffer F,Yildirim AÖ

    更新日期:2014-10-01 00:00:00

  • Pyelovenous and pyelolymphatic backflow during retrograde pyelography in renal vein thrombosis.

    abstract::Pyelovenous and pyelolymphatic backflow have been observed during retrograde pyelography in three patients with renal vein thrombosis. The radiographic patterns of backflow following experimental unilateral renal vein occlusion in rabbits were analyzed and correlated with the clinical findings. Capsular, perihilar, pe...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Bidgood WD Jr,Cuttino JT Jr,Clark RL,Volberg FM

    更新日期:1981-01-01 00:00:00

  • A computer program for the localization of small areas in roentgenological images.

    abstract::A method and associated algorithm are presented which allow a simple and accurate determination to be made of the location of small symmetric areas presented in roentgenological images. The method utilizes an operator to visually spot object positions but eliminates the need for critical positoning accuracy on the ope...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Keller RA,Baily NA

    更新日期:1976-03-01 00:00:00

  • Dynamic contrast-enhanced computed tomography as a potential biomarker in patients with metastatic renal cell carcinoma: preliminary results from the Danish Renal Cancer Group Study-1.

    abstract:OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

    journal_title:Investigative radiology

    pub_type: 杂志文章,随机对照试验


    authors: Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

    更新日期:2014-09-01 00:00:00

  • Sonography of the kidneys in hemolytic uremic syndrome.

    abstract::The sonographic appearance of kidneys in patients presenting with acute renal failure due to hemolytic-uremic syndrome (HUS) was evaluated and compared with that in an age-matched control series. In nine patients with HUS, the renal cortex was typically hyperechogenic and the renal pyramids appeared sonolucent. The re...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Kenney PJ,Brinsko RE,Patel DV,Spitzer RE,Farrar FM

    更新日期:1986-07-01 00:00:00