Microcomputer-based technique for 3-D reconstruction and volume measurement of computer tomographic images. Part 1: Phantom studies.


:This paper presents a microcomputer-based technique that accurately quantifies volumes from computed tomographic (CT) scans of irregularly shaped objects as well as displaying 3-D reconstructions. The method uses standard CT film, allowing analysis of previous or outside CT studies. The planimetry method showed less than 5% error in measuring irregular 2-D areas larger than 6 mm2. The method is demonstrated to be significantly more accurate than spherical, ellipsoid, or rectangular geometric models in quantifying object volume by CT (P less than .001). With a single gantry angle, planimetry showed a two standard deviation error under 10% in measuring the volume of irregular objects compared with an error over 30% for ellipsoid models. The inaccuracy of the spherical model (80% error) and the rectangular prism model (192% error) renders them impractical to provide quantitative object volume. Microcomputer planimetry provides an accurate and versatile means to measure the volume and produce 3-D reconstructions of objects scanned with CT, and it has potential application in quantifying tumor response with CT and magnetic resonance imaging.


Invest Radiol


Investigative radiology


Albright RE Jr,Fram EK




Has Abstract


1988-12-01 00:00:00












  • A new class of contrast agents for magnetic resonance imaging based on selective reduction of water-T2 by chemical exchange.

    abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Aime S,Nano R,Grandi M

    更新日期:1988-09-01 00:00:00

  • Detection of emphysema with computed tomography. Correlation with pulmonary function tests and chest radiography.

    abstract::We studied 60 male patients who had concurrent chest films (CXR), computed tomography scans (CT) and pulmonary function tests (PFT) to assess the sensitivity of CT and conventional films in detecting emphysema compared with PFT. We also sought to determine whether emphysema could be diagnosed by CT in patients with no...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Sanders C,Nath PH,Bailey WC

    更新日期:1988-04-01 00:00:00

  • Breast stereotactic core biopsy washings: abundant cell samples from clinically occult lesions for flow cytometric DNA analysis.

    abstract:RATIONALE AND OBJECTIVES:The object of this study was to determine by flow cytometry the cellular and DNA content of the washings of core biopsy samples and needles obtained during stereotactic core biopsies of clinically occult suspicious lesions. METHODS:Fourteen-gauge core multipass biopsy inner-needle saline washi...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Stomper PC,Budnick RM,Stewart CC

    更新日期:1998-01-01 00:00:00

  • The use of continuous and discrete confidence judgments in receiver operating characteristic studies of diagnostic imaging techniques.

    abstract::Virtually all receiver operating characteristic (ROC) studies of medical imaging methods have involved data collected on a discrete confidence-rating scale, though in principle ROC studies can be conducted with either discrete or continuous scales. Continuous scales provide potential advantages in medical applications...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Rockette HE,Gur D,Metz CE

    更新日期:1992-02-01 00:00:00

  • Three-dimensional ultrashort echo time imaging of solid polymers on a 3-Tesla whole-body MRI scanner.

    abstract:OBJECTIVE:With the introduction of ultrashort echo time (UTE) sequences solid polymeric materials might become visible on clinical whole-body magnetic resonance (MR) scanners. The aim of this study was to characterize solid polymeric materials typically used for instruments in magnetic resonance guided interventions an...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Springer F,Martirosian P,Schwenzer NF,Szimtenings M,Kreisler P,Claussen CD,Schick F

    更新日期:2008-11-01 00:00:00

  • Evaluation of the dehydration-rehydration method for production of contrast-carrying liposomes.

    abstract::We measured the amounts of three types of radiographic contrast media (RCM) that could be entrapped in liposomes prepared by the dehydration-rehydration vesicle (DRV) technique. To make DRVs, one initially makes water-containing, small unilamellar vesicles, adds contrast media and lyophilizes the mixture. Upon rehydra...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Seltzer SE,Gregoriadis G,Dick R

    更新日期:1988-02-01 00:00:00

  • Correlation of flow velocity measurements by magnetic resonance phase contrast imaging and intravascular Doppler ultrasound.

    abstract:RATIONALE AND OBJECTIVES:The authors compare the magnetic resonance (MR) phase contrast flow velocity measurements in varying concentric stenoses with invasive measurements obtained with a Doppler guidewire. METHODS:Flow velocity measurements were obtained using a calibrated 0.018 inch 12 MHz Doppler guidewire and a 1...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Hoppe M,Heverhagen JT,Froelich JJ,Kunisch-Hoppe M,Klose KJ,Wagner HJ

    更新日期:1998-08-01 00:00:00

  • Feasibility of real-time magnetic resonance-guided angioplasty and stenting of renal arteries in vitro and in Swine, using a new polyetheretherketone-based magnetic resonance-compatible guidewire.

    abstract:OBJECTIVES:Demonstrate the usability of a new polyetheretherketone (PEEK)-based MR-compatible guidewire for renal artery catheterization, angioplasty, and stenting under MR-guidance using MR-visible markers, in vitro and in vivo. MATERIAL AND METHODS:The new 0.035'' guidewire with fiber-reinforced PEEK core, a soft ti...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Kos S,Huegli R,Hofmann E,Quick HH,Kuehl H,Aker S,Kaiser GM,Borm PJ,Jacob AL,Bilecen D

    更新日期:2009-04-01 00:00:00

  • Contrast media-induced chromosomal damage in human lymphocyte cultures.

    abstract::Ionic (diatrizoate, ioxaglate) and nonionic (iohexol, iosimide, iopromide, and iotrolan) contrast media (CM) were evaluated for their cytogenetic effects in lymphocytes. Heparinized blood was mixed with culture medium RPMI-1640 supplemented with phytohemagglutinin, fetal calf serum, and antibiotics. Plastic tubes cont...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Parvez Z,Kormano M,Moncada R,Eklund R

    更新日期:1986-11-01 00:00:00

  • Ultra-low-dose, time-resolved contrast-enhanced magnetic resonance angiography of the carotid arteries at 3.0 tesla.

    abstract:PURPOSE:To determine whether time-resolved magnetic resonance angiography (TR-MRA) with ultra-low-dose gadolinium chelate (1.5-3.0 mL) can reliably detect or rule out hemodynamically significant disease in the carotid-vertebral artery territory. MATERIALS AND METHODS:Hundred consecutive patients (62 women, 38 men, mea...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Lohan DG,Tomasian A,Saleh RS,Singhal A,Krishnam MS,Finn JP

    更新日期:2009-04-01 00:00:00

  • Observer variation in detecting the radiologic features associated with bronchiolitis.

    abstract::Chest radiographs are commonly obtained to assess children for bronchiolitis, both to corroborate the diagnosis and to exclude other diagnostic possibilities. Their utility in this setting has not previously been examined. Using a blinded, randomized study design, we examined the interobserver and intraobserver variat...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Coblentz CL,Babcook CJ,Alton D,Riley BJ,Norman G

    更新日期:1991-02-01 00:00:00

  • Comparative evaluation of digital radiography versus conventional radiography of fractured skulls.

    abstract:OBJECTIVES:The authors assessed the relative efficacy of conventional and digital storage-phosphor radiographs for the detection of skull fractures. METHODS:Fifty conventional film-screen radiographs (FSR) and 50 digital storage-phosphor radiographs (DR) with 66 fractures were compared. Five radiologists evaluated ima...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Langen HJ,Klein HM,Wein B,Stargardt A,Günther RW

    更新日期:1993-08-01 00:00:00

  • Computer-aided detection for computed tomographic colonography screening: a prospective comparison of a double-reading paradigm with first-reader computer-aided detection against second-reader computer-aided detection.

    abstract:OBJECTIVES:The objective of this study was to prospectively compare diagnostic performance and time efficiency of a double-reading paradigm in which a first-reader computer-aided detection (CAD) is followed by a fast 2-dimensional review (DR FR-CAD) with those of a double reading with second-reader CAD (SR CAD). MATER...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Iussich G,Correale L,Senore C,Hassan C,Segnan N,Campanella D,Bert A,Galatola G,Laudi C,Regge D

    更新日期:2014-03-01 00:00:00

  • Assessment and reproducibility of aortic atherosclerosis magnetic resonance imaging: impact of 3-Tesla field strength and parallel imaging.

    abstract:OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Maroules CD,McColl R,Khera A,Peshock RM

    更新日期:2008-09-01 00:00:00

  • Advances in magnetic resonance (2006).

    abstract::Advances in the field of magnetic resonance (MR) as it pertains to clinical diagnostic radiology are examined in this review on the basis of publications in Investigative Radiology over the past 2 years (2005-2006). The articles published during that timeframe are discussed, organizationally wise, by anatomic region w...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审


    authors: Runge VM

    更新日期:2006-12-01 00:00:00

  • Comparison of Routine Brain Imaging at 3 T and 7 T.

    abstract:OBJECTIVE:The aim of this study was to compare quantitative and semiquantitative parameters (signal-to-noise ratio [SNR], contrast-to-noise ratio [CNR], image quality, diagnostic confidence) from a standard brain magnetic resonance imaging examination encompassing common neurological disorders such as demyelinating dis...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Springer E,Dymerska B,Cardoso PL,Robinson SD,Weisstanner C,Wiest R,Schmitt B,Trattnig S

    更新日期:2016-08-01 00:00:00

  • Screening mammography. A risk versus risk decision.

    abstract::The potential risk of a radiologic procedure often is compared with the potential benefit of the procedure. While risk vs. benefit analysis has been useful as a step toward increased communication and understanding among radiologists, referring physicians, and the general public, it has the disadvantage that risk and ...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审


    authors: Ritenour ER,Hendee WR

    更新日期:1989-01-01 00:00:00

  • Radiofrequency balloon angioplasty. Rationale and proof of principle.

    abstract::Post-angioplasty restenosis (PARS) in atherosclerotic lesions of medium and small arteries occurs in about one-third of cases in the first year following percutaneous transluminal angioplasty (PTA) (early PARS). PARS includes acute spasm, dissection with reclosure, elastic recoil, fibrocellular proliferative response,...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Becker GJ,Lee BI,Waller BF,Barry KJ,Kaplan J,Connolly R,Dreesen RG,Nardella P

    更新日期:1988-11-01 00:00:00

  • Ultrasound bone velocity on proximal phalanges in premenopausal, perimenopausal, and postmenopausal healthy women.

    abstract:RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Aguado F,Revilla M,Hernández ER,Villa LF,Rico H

    更新日期:1997-01-01 00:00:00

  • Retention of iodine and expression of biomarkers for renal damage in the kidney after application of iodinated contrast media in rats.

    abstract:OBJECTIVE:Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The ...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Jost G,Pietsch H,Sommer J,Sandner P,Lengsfeld P,Seidensticker P,Lehr S,Hütter J,Sieber MA

    更新日期:2009-02-01 00:00:00

  • Technical feasibility and performance studies of a 0.009-inch nitinol microguidewire for potential neuroendovascular applications.

    abstract:RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Putman CM,Chaloupka JC,Kailasnath P,Alderman J

    更新日期:1997-04-01 00:00:00

  • Magnetic resonance imaging using gadolinium labeled monoclonal antibody.

    abstract::Gadolinium was attached to antibodies and tested in vitro and in vivo for its effect on proton relaxation enhancement. Using the cyclic anhydride method, diethylenetriaminepentaacetic acid (DTPA) was attached to albumin, IgG and anti-CEA monoclonal antibody. Gadolinium (Gd) was then chelated to the protein complexes f...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Unger EC,Totty WG,Neufeld DM,Otsuka FL,Murphy WA,Welch MS,Connett JM,Philpott GW

    更新日期:1985-10-01 00:00:00

  • Timing and magnitude of the postural effect on the distribution of pulmonary blood flow.

    abstract::The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Kuribayashi S,Garnic JD,Abrams HL

    更新日期:1982-11-01 00:00:00

  • Time continuous tracking and segmentation of cardiovascular magnetic resonance images using multidimensional dynamic programming.

    abstract::In this article, we propose a semiautomatic method for time-continuous contour detection in all phases of the cardiac cycle in magnetic resonance sequences. The method is based on multidimensional dynamic programming. After shape parameterization, cost hypercubes are filled with image-feature derived cost function val...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Uzümcü M,van der Geest RJ,Swingen C,Reiber JH,Lelieveldt BP

    更新日期:2006-01-01 00:00:00

  • Characterization of radial forces in Z stents.

    abstract:RATIONAL AND OBJECTIVES:The purpose of this study was to evaluate the effects of variation in design parameters on the resultant radial force. We evaluated the influence of wire gauge, leg length, and number of bends on the radial force produced by z stents and compared these with radial forces produced by commercial s...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Snowhill PB,Nosher JL,Siegel RL,Silver FH

    更新日期:2001-09-01 00:00:00

  • Digital radiography versus conventional radiography for the detection of a skull fracture under varying exposure parameters.

    abstract:RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

    更新日期:1993-03-01 00:00:00

  • Low-osmolality contrast media-induced ventricular fibrillation.

    abstract::We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Hayakawa K,Yamashita K

    更新日期:1989-04-01 00:00:00

  • Evaluation of intrarenal oxygenation at 3.0 T using 3-dimensional multiple gradient-recalled echo sequence.

    abstract:OBJECTIVE:The objective of this study was to validate quantitation of R2* and DeltaR2* measurements obtained with a 3-dimensional (3-D) multiple gradient-recalled echo (mGRE) sequence for evaluating intrarenal oxygenation in humans. MATERIALS AND METHODS:Validation was accomplished (1) by comparing R2* values with pre...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Tumkur S,Vu A,Li L,Prasad PV

    更新日期:2006-02-01 00:00:00

  • Sclerotherapy of the gallbladder in pigs. Development of a balloon catheter for a single-step procedure.

    abstract::Gallbladder sclerotherapy after permanent cystic duct occlusion, to prevent gallstone recurrence in nonsurgical gallstone therapy, is at least a two-stage procedure. A balloon catheter was developed to perform gallbladder sclerotherapy with only temporary occlusion of the cystic duct, and the efficacy and safety of th...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Brakel K,Laméris JS,Vergunst H,Ten Kate FJ,Nijs HG,Terpstra OT

    更新日期:1991-09-01 00:00:00

  • Activities of the Conjoint Committee. Enhancement of diagnostic radiologic research and education.

    abstract::Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...

    journal_title:Investigative radiology

    pub_type: 杂志文章


    authors: Putman CE,Frank JA

    更新日期:1993-04-01 00:00:00