In vivo and in vitro evaluation of Gd-DTPA-polylysine as a macromolecular contrast agent for magnetic resonance imaging.

abstract：OBJECTIVES:The purposes of this study were to evaluate the reference range of quantitative computed tomography (QCT) measures of lung attenuation and airway parameter measurements in healthy nonsmoking adults and to identify sources of variation in those measures and possible means to adjust for them. MATERIALS AND ME...

journal_title：Investigative radiology

authors： Zach JA,Newell JD Jr,Schroeder J,Murphy JR,Curran-Everett D,Hoffman EA,Westgate PM,Han MK,Silverman EK,Crapo JD,Lynch DA,COPDGene Investigators.

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to conduct a radiopathologic evaluation of right-angled traction bronchiectasis to differentiate idiopathic pulmonary fibrosis (IPF) without honeycombing from idiopathic nonspecific interstitial pneumonia (NSIP). MATERIALS AND METHODS:The derivation cohort included 78 consecutive p...

journal_title：Investigative radiology

authors： Kim H,Yoon SH,Lee HJ,Song SG,Koh J,Jeon YK,Chae KJ,Jin GY,Jin KN,Lee KY,Goo JM

更新日期：2020-06-01 00:00:00

abstract：:An allergic, immunologic mechanism for certain adverse reactions to radiocontrast agents has been postulated on the basis of clinical and theoretical considerations. One obstacle to the acceptance of this allergic theory has been the inability to demonstrate significant antibodies with specificity for these agents. In...

journal_title：Investigative radiology

authors： Brasch RC,Caldwell JL

更新日期：1976-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：:Maximum likelihood estimation, assuming a binormal model, has been used extensively to estimate the area under receiver operating characteristic (ROC) curves and thus provide an index of diagnostic accuracy for the comparison of two imaging systems. However, in some instances, a degenerate data set results in a fitted...

journal_title：Investigative radiology

authors： Rockette HE,Obuchowski NA,Gur D

更新日期：1990-07-01 00:00:00

abstract：:Although general suggestions have been made regarding a radiology residency curriculum, no specific list of entities has been offered. Over the past ten years, we have developed a resident-run morning conference in musculoskeletal radiology that is supervised by faculty and covers a specific curriculum. We offer our c...

journal_title：Investigative radiology

authors： Renfrew DL,el-Khoury GY,Moore TE,Kathol MH,Whitten CG,Walker CW,Fraser-Hill MA

更新日期：1991-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...

journal_title：Investigative radiology

authors： Roobottom CA,Farrow R,Wells IP,Hurlock-Fimls N

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:We sought to prospectively evaluate the image quality and visualization of the intracranial arteries using high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) at 3 T and to perform intraindividual comparison with time-of-flight (TOF) MRA and multislice CT angiography (CTA). MATERI...

journal_title：Investigative radiology

authors： Villablanca JP,Nael K,Habibi R,Nael A,Laub G,Finn JP

更新日期：2006-11-01 00:00:00

abstract：:Radiation dose in computed tomography (CT) has become a hot topic due to an upward trend in the number of CT procedures worldwide and the relatively high doses associated with these procedures. The main aim of this review article is to provide an overview of the most frequently used metrics for CT radiation dose chara...

journal_title：Investigative radiology

authors： Damilakis J

更新日期：2021-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...

journal_title：Investigative radiology

authors： Schürmann K,Vorwerk D,Kulisch A,Stroehmer-Kulisch E,Biesterfeld S,Stopinski T,Günther RW

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVES:The aim of this work was to quantitatively evaluate the pharmacokinetic pattern of Gd-EOB-DTPA in a model of isolated and perfused mouse liver by using magnetic resonance imaging (MRI) and monochromatic quantitative computed tomography (MQCT). MATERIALS AND METHODS:For MQCT, perfusions were realized with th...

journal_title：Investigative radiology

authors： Segers J,Le Duc G,Laumonier C,Troprès I,Elst LV,Muller RN

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS:Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-t...

journal_title：Investigative radiology

authors： Tsuboyama T,Jost G,Pietsch H,Tomiyama N

更新日期：2017-09-01 00:00:00

abstract：:Gastrografin and Amipaque with identical iodine content and flavoring were orally administered in 100 ml doses to 10 healthy volunteers in a double-blind crossover study. The nonionic Amipaque has only about one third of the osmolality of Gastrografin, and draws less fluid into the bowel lumen. Consequently there is l...

journal_title：Investigative radiology

authors： Johansen JG

更新日期：1978-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The clinically most widely used devices (Porstmann-plug, Rashkind-umbrella, Botallooccluder) have inherent specific limitations (eg, transarterial approach, residual shunts, limited retrieval). The authors assess practicability, efficacy, and tissue reaction of the new retrievable transvenous p...

journal_title：Investigative radiology

authors： Grabitz RG,Schräder R,Sigler M,Seghaye MC,Dzionsko C,Handt S,Schneidt B,Von Bernuth G

更新日期：1997-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...

journal_title：Investigative radiology

authors： Putman CM,Chaloupka JC,Kailasnath P,Alderman J

更新日期：1997-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors compare the magnetic resonance (MR) phase contrast flow velocity measurements in varying concentric stenoses with invasive measurements obtained with a Doppler guidewire. METHODS:Flow velocity measurements were obtained using a calibrated 0.018 inch 12 MHz Doppler guidewire and a 1...

journal_title：Investigative radiology

authors： Hoppe M,Heverhagen JT,Froelich JJ,Kunisch-Hoppe M,Klose KJ,Wagner HJ

更新日期：1998-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To determine whether vascular endothelial growth factor (VEGF) is a histopathological factor influencing contrast enhancement of hepatocellular carcinoma (HCC) on computed tomography (CT). METHODS:Twenty-two nodular HCCs underwent multiphase helical CT and surgery. Tumor size, histological gra...

journal_title：Investigative radiology

authors： Kwak BK,Shim HJ,Park ES,Kim SA,Choi D,Lim HK,Park CK,Chung JW,Park JH

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

journal_title：Investigative radiology

authors： Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate accuracy of biliary anatomy depiction and quality of biliary tract visualization of magnetic resonance cholangiography (MRC) at 3.0 T in living potential liver donors (LPLDs). MATERIALS AND METHODS:Our institutional review board approved this study and did not require patient's inf...

journal_title：Investigative radiology

authors： Kim SY,Byun JH,Hong HS,Choi EK,Lee SS,Park SH,Lee MG

更新日期：2008-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The ventral sacroiliac ligament (VSL), which bridges the sacroiliac (SI) joint anteriorly, has been described as an important stabilizing structure of the joint, but no data exist regarding its assessment with routine and advanced imaging methods. The authors determine the imaging appearance of...

journal_title：Investigative radiology

authors： Jaovisidha S,Ryu KN,De Maeseneer M,Haghighi P,Goodwin D,Sartoris DJ,Resnick D

更新日期：1996-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...

journal_title：Investigative radiology

authors： Mao S,Child J,Carson S,Liu SC,Oudiz RJ,Budoff MJ

更新日期：2003-03-01 00:00:00

abstract：:A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...

journal_title：Investigative radiology

authors： Powers TA,Rees RS,Bowen RD

更新日期：1983-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the effect of the transverse ligament on translation of the menisci. METHODS:Six cadaveric knees were examined by MR imaging inside a positioning device before and after transecting the transverse ligament. The knees were examined at various positions: extension, 30 degrees of flex...

journal_title：Investigative radiology

authors： Muhle C,Thompson WO,Sciulli R,Pedowitz R,Ahn JM,Yeh L,Clopton P,Haghighi P,Trudell DJ,Resnick D

更新日期：1999-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Two independent gold standards and diagnoses from three-dimensional computed tomography (CT) images were used to examine the possibility that craniosynostosis is a binary abnormality that potentially may be diagnosed without error. METHODS:Surgical reports, histology of excised sutures, and th...

journal_title：Investigative radiology

authors： Pilgram TK,Vannier MW,Marsh JL,Kraemer BB,Rayne SC,Gado MH,Moran CJ,McAlister WH,Shackelford GD,Hardesty RA

更新日期：1994-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...

journal_title：Investigative radiology

authors： Oudkerk M,Sijens PE,Van Beek EJ,Kuijpers TJ

更新日期：1995-02-01 00:00:00

abstract：:An agent has been identified in lymph from rat kidneys rendered ischemic by partial renal artery occlusion that induces a striking neovascular response in a hamster cheek-pouch assay system. The factor has a high molecular weight, cannot be identified in lymph from normal kidneys, and is associated with a marked incre...

journal_title：Investigative radiology

authors： Hollenberg NK,Paskins-Hurlburt AJ,Abrams HL

更新日期：1985-01-01 00:00:00

abstract：:Thirty patients [four normals, eight with mild and 18 with severe coronary artery disease (CAD)] were studied to evaluate left ventricular function type and post coronary angiography. The end diastolic volume (EDV), end systolic volume (ESV), ejection fraction (EF) and the regional contractility fractions (RCF) of eig...

journal_title：Investigative radiology

authors： Sos TA,Baltaxe HA

更新日期：1976-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To characterize the long-term effects of therapeutic doses of ionizing radiation on the uptake and distribution of percutaneously delivered particulate contrast media in normal lymph nodes. METHODS:Two milliliters of an iodinated nanoparticle suspension (76 mg I/mL) was injected subcutaneously...

journal_title：Investigative radiology

authors： Wisner ER,Théon A,Griffey SM,McIntire GL

更新日期：2000-03-01 00:00:00

abstract：:A method is presented by whichcomputed tomography scans carried out at a number of energies may be utilized to obtain cross-sectional images of density and atomic number in addition to the conventional array of linear attenuation coefficients. This type of analysis has been carried out for various substances of biolog...

journal_title：Investigative radiology

authors： McDavid WD,Waggener RG,Dennis MJ,Sank VJ,Payne WH

更新日期：1977-03-01 00:00:00