Estimation of chemical composition and density from computed tomography carried out at a number of energies.

Abstract:

:A method is presented by whichcomputed tomography scans carried out at a number of energies may be utilized to obtain cross-sectional images of density and atomic number in addition to the conventional array of linear attenuation coefficients. This type of analysis has been carried out for various substances of biological relevance. Computer simulated reconstructions of clinical situations suggest that the method shows promise for providing additional diagnostic information and might dispense to some extent with the necessity of injecting contrast agents into the patient.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

McDavid WD,Waggener RG,Dennis MJ,Sank VJ,Payne WH

doi

10.1097/00004424-197703000-00016

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

189-94

issue

2

eissn

0020-9996

issn

1536-0210

journal_volume

12

pub_type

杂志文章
  • Tamm-Horsfall glycoprotein excretion and aggregation during intravenous urography. Relevance to acute renal failure.

    abstract::The effect of intravenous urography (IVU) on the excretion rate and precipitation of Tamm-Horsfall glycoprotein (THG) has been evaluated in 19 patients. Urine samples were collected immediately before the administration of contrast medium (U1) and then during the period of the excretion urogram (U2). The urinary THG: ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198501000-00014

    authors: Dawnay AB,Thornley C,Nockler I,Webb JA,Cattell WR

    更新日期:1985-01-01 00:00:00

  • Prediction of antiangiogenic treatment efficacy by iron oxide enhanced parametric magnetic resonance imaging.

    abstract:RATIONALE AND OBJECTIVES:Tools for monitoring modern target-specific antiangiogenic and antivascular therapies are highly desirable because treatment strategies are time consuming, expensive, and yet sometimes ineffective. Therefore, the aim of this experimental study was to evaluate the predictive value of steady-stat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3180d5cbd9

    authors: Persigehl T,Matuszewski L,Kessler T,Wall A,Meier N,Ebert W,Berdel WE,Heindel W,Mesters R,Bremer C

    更新日期:2007-12-01 00:00:00

  • A computer program for the localization of small areas in roentgenological images.

    abstract::A method and associated algorithm are presented which allow a simple and accurate determination to be made of the location of small symmetric areas presented in roentgenological images. The method utilizes an operator to visually spot object positions but eliminates the need for critical positoning accuracy on the ope...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197603000-00007

    authors: Keller RA,Baily NA

    更新日期:1976-03-01 00:00:00

  • Scatter compensation in digital chest radiography using Fourier deconvolution.

    abstract::The authors present a numerical deconvolution technique to compensate for image degrading effects caused by scattered photons in radiographic chest images. Fourier transform techniques are used to deconvolve a shift invariant model of the two dimensional point spread response functions of the scattered radiation. This...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198901000-00008

    authors: Floyd CE,Beatty PT,Ravin CE

    更新日期:1989-01-01 00:00:00

  • Temperature-Sensitive Frozen-Tissue Imaging for Cryoablation Monitoring Using STIR-UTE MRI.

    abstract:PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000642

    authors: Tokuda J,Wang Q,Tuncali K,Seethamraju RT,Tempany CM,Schmidt EJ

    更新日期:2020-05-01 00:00:00

  • Minimal spinal hyperostosis with low-dose isotretinoin therapy.

    abstract::Skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin A and its derivatives. Recently, a new derivative, isotretinoin (Accutane, Hoffman-LaRoche, Inc.), has become available for the treatment of cystic acne. Ninety-six patients treated for a minimum of four...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198601000-00007

    authors: Kilcoyne RF,Cope R,Cunningham W,Nardella FA,Denman S,Franz TJ,Hanifin J

    更新日期:1986-01-01 00:00:00

  • Radiofrequency balloon angioplasty. Rationale and proof of principle.

    abstract::Post-angioplasty restenosis (PARS) in atherosclerotic lesions of medium and small arteries occurs in about one-third of cases in the first year following percutaneous transluminal angioplasty (PTA) (early PARS). PARS includes acute spasm, dissection with reclosure, elastic recoil, fibrocellular proliferative response,...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/00004424-198811000-00002

    authors: Becker GJ,Lee BI,Waller BF,Barry KJ,Kaplan J,Connolly R,Dreesen RG,Nardella P

    更新日期:1988-11-01 00:00:00

  • High permittivity dielectric pads improve high spatial resolution magnetic resonance imaging of the inner ear at 7 T.

    abstract:OBJECTIVES:The objective of this study was to evaluate the use of dielectric pads for improving high spatial resolution imaging of the inner ear at 7 T. MATERIALS AND METHODS:Two sets of dielectric pads were designed using electromagnetic simulations and implemented using a deuterated suspension of barium titanate. Th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000026

    authors: Brink WM,van der Jagt AM,Versluis MJ,Verbist BM,Webb AG

    更新日期:2014-05-01 00:00:00

  • Preclinical profile of the monodisperse iodinated macromolecular blood pool agent P743.

    abstract:RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200101000-00006

    authors: Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

    更新日期:2001-01-01 00:00:00

  • Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrast medium enhancement.

    abstract:PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000167421.83203.4e

    authors: Diekmann F,Diekmann S,Jeunehomme F,Muller S,Hamm B,Bick U

    更新日期:2005-07-01 00:00:00

  • Molecular magnetic resonance imaging allows the detection of activated platelets in a new mouse model of coronary artery thrombosis.

    abstract:OBJECTIVE:: The final event leading to myocardial infarction is adhesion and activation of platelets after rupture of an atherosclerotic plaque, ending in thrombotic occlusion of the coronary artery. Imaging of imminent vessel occlusion may improve patient care. The feasibility of molecular magnetic resonance imaging (...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31821e62fb

    authors: Duerschmied D,Meißner M,Peter K,Neudorfer I,Roming F,Zirlik A,Bode C,von Elverfeldt D,von Zur Muhlen C

    更新日期:2011-10-01 00:00:00

  • Bone mineral analysis using single-energy computed tomography.

    abstract::We present a new method for evaluating in vivo changes in bone mineralization in the peripheral skeleton, using computed tomography (CT). A set of bone mineralization indices are generated from numerous CT images of the patient's distal radius. The cross-sectional anatomy displayed by the CT scan allows for separate e...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197903000-00003

    authors: Orphanoudakis SC,Jensen PS,Rauschkolb EN,Lang R,Rasmussen H

    更新日期:1979-03-01 00:00:00

  • In vitro complement consumption by contrast materials and analogues: reactors vs. nonreactors.

    abstract::Blood samples from previous contrast reactors and nonreactor controls were incubated with diatrizoate and several contrast analogues. Total complement levels were assayed. All the agents caused complement activation generally proportional to their concentration. Reactors' sera responded to lower concentrations of cont...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198307000-00018

    authors: Siegle RL,Lieberman P,Rice MC

    更新日期:1983-07-01 00:00:00

  • Computed Tomography for 4-Dimensional Angiography and Perfusion Imaging of the Prostate for Embolization Planning of Benign Prostatic Hyperplasia.

    abstract:OBJECTIVES:The aim of this study was to evaluate the feasibility of a computed tomography (CT) protocol enabling the visualization of the prostatic artery (PA) before prostatic artery embolization (PAE) in benign prostatic hyperplasia, which provides quantitative perfusion information of the prostate gland. MATERIALS ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000582

    authors: Kobe A,Puippe G,Klotz E,Alkadhi H,Pfammatter T

    更新日期:2019-10-01 00:00:00

  • Observation on the metabolism of iopanoyl (Telepaque) glucuronide in dogs treated with antibiotics.

    abstract::The purpose of our investigation was to determine whether iopanoyl glucuronide, the major metabolite of iopanoic acid (Telepaque), undergoes hydrolysis by bacterial beta-glucuronidase in dogs. The conjugated compound was identified and quantitated by elemental analysis, fluorescent excitation analysis, thin-layer chro...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197805000-00011

    authors: Thoeni RF,Goldberg HI,Moss AA,Lin SK,Brito AC

    更新日期:1978-05-01 00:00:00

  • Radiolabeled leukocytes and platelets.

    abstract::Radiolabeled blood cells are widely used for both clinical and research studies. In vitro and in vivo studies have shown the tagging process does not significantly affect function. The labeling techniques and clinical uses of labeled leukocytes and platelets are reviewed. ...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-198603000-00001

    authors: Datz FL

    更新日期:1986-03-01 00:00:00

  • The allergic theory of radiocontrast agent toxicity: demonstration of antibody activity in sera of patients suffering major radiocontrast agent reactions.

    abstract::An allergic, immunologic mechanism for certain adverse reactions to radiocontrast agents has been postulated on the basis of clinical and theoretical considerations. One obstacle to the acceptance of this allergic theory has been the inability to demonstrate significant antibodies with specificity for these agents. In...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197609000-00002

    authors: Brasch RC,Caldwell JL

    更新日期:1976-09-01 00:00:00

  • Assessment and reproducibility of aortic atherosclerosis magnetic resonance imaging: impact of 3-Tesla field strength and parallel imaging.

    abstract:OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e318181538a

    authors: Maroules CD,McColl R,Khera A,Peshock RM

    更新日期:2008-09-01 00:00:00

  • Contrast media for CT. An analysis of the early pharmacokinetics.

    abstract::Iohexol and meglumine-sodium diatrizoate were injected intravenously into 18 pigs as either a 99:1 or 1:99 mixture. Blood samples were taken for 30 minutes and the concentration of each of the two contrast media was measured by means of a double labeling technique with 125I and 131I. Relative concentrations of iohexol...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198511000-00016

    authors: Jensen LI,Dean PB,Nyman U,Golman K

    更新日期:1985-11-01 00:00:00

  • A double-blind comparative study of Hexabrix and Renografin-76 in aortography and visceral arteriography.

    abstract::A diatrizoate compound (Renografin-76) and low osmolality Hexabrix were compared in a double-blind study of 50 adults undergoing arteriographic examination. Subjective and objective assessment of pain reaction for each contrast injection rated lower overall for Hexabrix. Discomfort associated with Renografin was great...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00004424-198411001-00012

    authors: Barth KH,Mertens MA

    更新日期:1984-11-01 00:00:00

  • Pharmacokinetics and safety of gadobutrol-enhanced magnetic resonance imaging in pediatric patients.

    abstract:OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181bfe2d2

    authors: Hahn G,Sorge I,Gruhn B,Glutig K,Hirsch W,Bhargava R,Furtner J,Born M,Schröder C,Ahlström H,Kaiser S,Moritz JD,Kunze CW,Shroff M,Stokland E,Trnkova ZJ,Schultze-Mosgau M,Reif S,Bacher-Stier C,Mentzel HJ

    更新日期:2009-12-01 00:00:00

  • In vivo and in vitro evaluation of Gd-DTPA-polylysine as a macromolecular contrast agent for magnetic resonance imaging.

    abstract::Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199111000-00008

    authors: Schuhmann-Giampieri G,Schmitt-Willich H,Frenzel T,Press WR,Weinmann HJ

    更新日期:1991-11-01 00:00:00

  • The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation, and vascularization.

    abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199306000-00011

    authors: Ni Y,Marchal G,Zhang X,Van Hecke P,Michiels J,Yu J,Rummeny E,Lodemann KP,Baert AL

    更新日期:1993-06-01 00:00:00

  • Radioimmunodetection of a transplantable human bladder carcinoma in a nude mouse.

    abstract::The results of an in vitro mixed hemadsorption (MHA) assay predicted the success of in vivo tumor localization using a radioiodinated, monoclonal, IgG1 antibody (A2) with reactivity to the human bladder carcinoma cell line RT4. In vitro, murine monoclonal antibodies A2 and G6, demonstrated reactivity to RT4 with titer...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198411000-00011

    authors: Gross MD,Skinner RW,Grossman HB

    更新日期:1984-11-01 00:00:00

  • Towards computer analysis of pulmonary infiltration.

    abstract::A feasibility study is described to provide quantitative texture measures to distinguish between normal lung, alveolar infiltrates and interstitial infiltrates. Advanced computer imaging technology and decision making processes were applied to distinguish between these textural patterns. The results, based on computer...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197807000-00005

    authors: Tully RJ,Conners RW,Harlow CA,Lodwick GS

    更新日期:1978-07-01 00:00:00

  • Interference of gadolinium-containing contrast-enhancing agents with colorimetric calcium laboratory testing.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000170447.45577.5e

    authors: Löwe A,Balzer T,Hirt U

    更新日期:2005-08-01 00:00:00

  • Does dilution of contrast media affect contrast enhancement? An experimental study in rats.

    abstract::The effect of contrast media (CM) dilution on contrast enhancement was studied using CM representing four structurally different molecular types at osmolalities ranging from 135 to 1340 mosm/kg. Diatrizoate (ionic monomer), iopamidol (nonionic monomer), ioxaglate (ionic dimer), and iodecol (nonionic dimer) were each g...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198809001-00014

    authors: Dean PB,Kivisaari L,Kormano M

    更新日期:1988-09-01 00:00:00

  • Efficacy of gadoteridol for magnetic resonance imaging of the brain and spine.

    abstract:RATIONALE AND OBJECTIVES:The efficacy of gadoteridol for contrast enhancement of central nervous system pathology was assessed in a multicenter clinical trial involving 411 patients suspected of having intracranial or spinal pathology. METHODS:Magnetic resonance imaging was performed before and after intravenous admin...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Runge VM,Bronen RA,Davis KR

    更新日期:1992-08-01 00:00:00

  • The retropsoas recess. Demonstration using computed tomography.

    abstract::The retropsoas recess, a previously undescribed normal anatomic variant, is reported. In most individuals, the space posterior to the belly of the psoas muscle contains fat within the posterior pararenal space. However, a retrospective review of 250 consecutive CT examinations of the abdomen revealed 11 cases (4.4%) i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198707000-00004

    authors: Kelly RB,Mahoney PD,Frick MP

    更新日期:1987-07-01 00:00:00

  • Measurement of distensibility of blood vessels using cineangiograms.

    abstract::We developed a new, cineangiographic method to accurately measure the dynamic changes in the internal diameter of human arteries in vivo. Cine films were digitized at a spatial resolution of 4 microns/pixel, using a line image sensor. The vessel edges, with a Gaussian fit to a unilateral profile curve of the vessel, w...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198909000-00005

    authors: Sugahara T,Yanagihara Y,Uyama C,Maeda H,Takafuchi M,Azumi T

    更新日期:1989-09-01 00:00:00