Contrast media for CT. An analysis of the early pharmacokinetics.

abstract：OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...

journal_title：Investigative radiology

authors： Quattrocchi CC,Errante Y,Mallio CA,Marinelli L,LoVullo G,Giannotti G,Della Sala SW,van der Molen AJ,Beomonte Zobel B

更新日期：2018-04-01 00:00:00

abstract：:We present a new method for evaluating in vivo changes in bone mineralization in the peripheral skeleton, using computed tomography (CT). A set of bone mineralization indices are generated from numerous CT images of the patient's distal radius. The cross-sectional anatomy displayed by the CT scan allows for separate e...

journal_title：Investigative radiology

authors： Orphanoudakis SC,Jensen PS,Rauschkolb EN,Lang R,Rasmussen H

更新日期：1979-03-01 00:00:00

abstract：:We compared the damage resulting from intradermal injection of four commonly used radiographic contrast media in laboratory rats. Sixty percent meglumine diatrizoate (Reno M 60) and ioxaglate (Hexabrix) produced significantly more ulceration and crusting on gross inspection and more necrosis, edema, and hemorrhage on ...

journal_title：Investigative radiology

authors： Cohan RH,Leder RA,Bolick D,Herzberg AJ,Hedlund LW,Wheeler CT,Helms MJ,Dunnick NR

更新日期：1990-05-01 00:00:00

abstract：:Although general suggestions have been made regarding a radiology residency curriculum, no specific list of entities has been offered. Over the past ten years, we have developed a resident-run morning conference in musculoskeletal radiology that is supervised by faculty and covers a specific curriculum. We offer our c...

journal_title：Investigative radiology

authors： Renfrew DL,el-Khoury GY,Moore TE,Kathol MH,Whitten CG,Walker CW,Fraser-Hill MA

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility of adenosine-stress dynamic myocardial volume perfusion imaging with second generation dual source computed tomography (CT) for the qualitative and quantitative assessment of myocardial blood flow (MBF) compared with stress perfusion and viability magnetic resonance imaging (MRI). ...

journal_title：Investigative radiology

authors： Bastarrika G,Ramos-Duran L,Rosenblum MA,Kang DK,Rowe GW,Schoepf UJ

更新日期：2010-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study was devised to develop a method of measuring the acute effects of radiocontrast media on renal function and assessing the relationship of the dose of radiocontrast media infused with the incidence of radiocontrast-induced renal failure. In addition, the drug adenosine phosphate-magne...

journal_title：Investigative radiology

authors： Albert SG,Shapiro MJ,Brown WW,Goodgold H,Zuckerman D,Durham R,Kern M,Fletcher J,Wolverson M,Plummer ES

更新日期：1994-06-01 00:00:00

abstract：:The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Bloo...

journal_title：Investigative radiology

authors： Fike JR,Cann CE,Norman D,Turrel JM,LeCouteur RA,Pflugfeld CM,Borcich JK

更新日期：1984-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Measurements of segmental contraction of the left ventricle by standard magnetic resonance imaging (MRI) and two-dimensional echocardiography involve the comparison of diastolic and systolic time frames acquired from the same imaging plane in space. As the cone-shaped left ventricle shortens al...

journal_title：Investigative radiology

authors： Pattynama PM,Doornbos J,Hermans J,van der Wall EE,de Roos A

更新日期：1992-09-01 00:00:00

abstract：:We studied 60 male patients who had concurrent chest films (CXR), computed tomography scans (CT) and pulmonary function tests (PFT) to assess the sensitivity of CT and conventional films in detecting emphysema compared with PFT. We also sought to determine whether emphysema could be diagnosed by CT in patients with no...

journal_title：Investigative radiology

authors： Sanders C,Nath PH,Bailey WC

更新日期：1988-04-01 00:00:00

abstract：:Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented. ...

journal_title：Investigative radiology

authors： Enge I

更新日期：1985-01-01 00:00:00

abstract：:Electromagnetic flow measurement study was performed in 20 anesthetized dogs to evaluate the effect of selective celiac infusion of vasopressin on the hepatic arterial vasculature. Teh hepatic arterial flow showed a biphasic response with an initial decrease followed by a substantial increase in spite of a continued ...

journal_title：Investigative radiology

authors： Barr JW,Lakin RC,Rösch J

更新日期：1975-05-01 00:00:00

abstract：:The residency program at the University of Pennsylvania offers a 1-month fellowship for senior residents in medical student education. Instructional philosophy, methods, and content are discussed, observed, practiced, and evaluated. Close supervision and immediate feedback provide training particularly needed by futur...

journal_title：Investigative radiology

authors： Troupin RH

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVE:With the introduction of ultrashort echo time (UTE) sequences solid polymeric materials might become visible on clinical whole-body magnetic resonance (MR) scanners. The aim of this study was to characterize solid polymeric materials typically used for instruments in magnetic resonance guided interventions an...

journal_title：Investigative radiology

authors： Springer F,Martirosian P,Schwenzer NF,Szimtenings M,Kreisler P,Claussen CD,Schick F

更新日期：2008-11-01 00:00:00

abstract：:Surgical resection is the standard of care for colorectal metastases isolated to the liver. However, only 10-25% of the patients are eligible for resection because of extent and location of the disease in the liver or concurrent medical conditions. Image-guided radiofrequency (RF) ablation is a minimally invasive tech...

journal_title：Investigative radiology

authors： Lencioni R,Crocetti L,Cioni D,Della Pina C,Bartolozzi C

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to prospectively compare diagnostic performance and time efficiency of a double-reading paradigm in which a first-reader computer-aided detection (CAD) is followed by a fast 2-dimensional review (DR FR-CAD) with those of a double reading with second-reader CAD (SR CAD). MATER...

journal_title：Investigative radiology

authors： Iussich G,Correale L,Senore C,Hassan C,Segnan N,Campanella D,Bert A,Galatola G,Laudi C,Regge D

更新日期：2014-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A new hepatobiliary gadolinium chelate, gadolinium (Gd) 2,5-BPA-DO3A, was compared in two animal species with Gd HP-DO3A (gadoteridol), a clinically approved extracellular contrast agent, and Gd Cy2-DOTA, a second hepatobiliary chelate in preclinical development. The ligand in Gd 2,5-BPA-DO3A i...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Williams NM

更新日期：1996-01-01 00:00:00

abstract：:The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...

journal_title：Investigative radiology

authors： Kuribayashi S,Garnic JD,Abrams HL

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVES:To determine the impact of slice thickness on semiautomatic lymph node analysis. MATERIALS AND METHODS:Thoracic multislice computed tomography (MSCT) of 46 patients with NSCLC were reconstructed at 1.0-, 3.0-, and 5.0-mm slice thickness. Two radiologists independently determined long and short axis diameter...

journal_title：Investigative radiology

authors： Buerke B,Puesken M,Beyer F,Gerss J,Weckesser M,Seifarth H,Heindel W,Wessling J

更新日期：2010-02-01 00:00:00

abstract：:The problem of inhomogeneous mixing encountered during hepatic artery (HA) chemotherapy infusion was assessed and a practical solution examined. A glass model of the human HA distribution was used to determine mixing homogeneity of low flow (1.4 mL/minute) dye infusion into pulsatile flow (280-300 mL/minute) of a flui...

journal_title：Investigative radiology

authors： Barth KH,Lutz RJ,Kremers PW,Miller DL

更新日期：1988-07-01 00:00:00

abstract：:Blood samples from previous contrast reactors and nonreactor controls were incubated with diatrizoate and several contrast analogues. Total complement levels were assayed. All the agents caused complement activation generally proportional to their concentration. Reactors' sera responded to lower concentrations of cont...

journal_title：Investigative radiology

authors： Siegle RL,Lieberman P,Rice MC

更新日期：1983-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors analyze the origins of the "clotting issue," the controversy that began in the 1980s when contrast media, once perceived as good flushing agents for catheters because of their assumed anticoagulant properties, came under attack for allegedly causing thromboembolism. Laboratory studi...

journal_title：Investigative radiology

authors： Dawson P,Cousins C,Bradshaw A

更新日期：1993-11-01 00:00:00

abstract：:The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...

journal_title：Investigative radiology

authors： Ferrante SL,Schreiman JS,Rouse JW,Rysavy JA,Cheng SC,Frick MP

更新日期：1990-02-01 00:00:00

abstract：:The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...

journal_title：Investigative radiology

authors： Fajardo LL,Yoshino MT,Seeley GW,Hunt R,Hunter TB,Friedman R,Cardenas D,Boyle R

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

journal_title：Investigative radiology

authors： Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

更新日期：2015-03-01 00:00:00

abstract：:The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and loca...

journal_title：Investigative radiology

authors： Mironidou M,Ximitidou O,Christopoulos S,Kokkas B

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the prognostic utility of a staging system using magnetic resonance imaging (MRI) with the seventh American Joint Committee on Cancer (AJCC) staging system in patients with hepatocellular carcinoma (HCC) who underwent hepatic resection. MATERIALS AND METHODS:A total of 1...

journal_title：Investigative radiology

authors： An C,Choi GH,Lee HS,Kim MJ

更新日期：2012-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00

abstract：:The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...

journal_title：Investigative radiology

authors： Wikström MG,Moseley ME,White DL,Dupon JW,Winkelhake JL,Kopplin J,Brasch RC

更新日期：1989-08-01 00:00:00

abstract：:Using a 1.5 T magnetic resonance imaging (MRI) system, cine phase-contrast and magnitude images were obtained in three phantoms that simulated different anatomic configurations of aortic dissection. The dissection phantoms were made of compliant materials, and pulsatile flow was used in all experiments. Phantoms diffe...

journal_title：Investigative radiology

authors： Iwai F,Sostman HD,Evans AJ,Nadel SN,Hedlund LW,Beam CA,Charles HC,Spritzer CE

更新日期：1991-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study evaluated the value of dynamically enhanced fast low-angle shot (FLASH) magnetic resonance (MR) imaging in measuring cardiac output with and without dipyridamole pharmacological stress. METHODS:Ten subjects underwent rest and stress MR imaging. Rest images were acquired using electr...

journal_title：Investigative radiology

authors： Tello R,Hartnell GG,Hill TC,Cerel A,Finn JP,Kamalesh M,Cohen M,Lewis S

更新日期：1996-11-01 00:00:00