Relative uptake of low- and high-osmolality contrast media in CT of brain tumors.

Abstract:

:The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Blood iodine was measured using x-ray fluorescence. Peak contrast enhancement occurred during the infusion, and the magnitude was the same for both agents. Per gram of iodine infused, blood iodine was 12.4% higher with ioxaglate than iothalamate. The monoionic dimer ioxaglate is as effective as iothalamate for enhancement of canine brain tumors.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Fike JR,Cann CE,Norman D,Turrel JM,LeCouteur RA,Pflugfeld CM,Borcich JK

doi

10.1097/00004424-198411001-00007

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

S312-6

issue

6 Suppl

eissn

0020-9996

issn

1536-0210

journal_volume

19

pub_type

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