Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best?

Abstract:

RATIONALE AND OBJECTIVES:To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status. MATERIAL AND METHODS:High-resolution magnetic resonance images of the calcaneus and the distal radius and thin-section computed tomographic images of thoracic and lumbar vertebrae were obtained from 74 cadavers. Structure analysis was performed using parameters analogous to standard histomorphometry. BMD of the spine was determined by using quantitative computed tomography and of the calcaneus by using dual x-ray absorptiometry. Spine radiographs of these cadavers were assessed concerning vertebral deformities. RESULTS:The diagnostic performance in differentiating fracture and nonfracture subjects was highest for structure parameters in the spine and slightly lower for these parameters in the distal radius and for BMD of the spine. CONCLUSION:In this study structure parameters in the spine were best suited to predict the osteoporotic fracture status of the spine.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Link TM,Bauer J,Kollstedt A,Stumpf I,Hudelmaier M,Settles M,Majumdar S,Lochmüller EM,Eckstein F

doi

10.1097/01.rli.0000129154.50654.4e

keywords:

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

487-97

issue

8

eissn

0020-9996

issn

1536-0210

pii

00004424-200408000-00006

journal_volume

39

pub_type

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