Abstract:
RATIONALE AND OBJECTIVES:The effect of breathholding on pulmonary perfusion remains largely unknown. The aim of this study was to assess the effect of inspiratory and expiratory breathhold on pulmonary perfusion using quantitative pulmonary perfusion magnetic resonance imaging (MRI). METHODS AND RESULTS:Nine healthy volunteers (median age, 28 years; range, 20-45 years) were examined with contrast-enhanced time-resolved 3-dimensional pulmonary perfusion MRI (FLASH 3D, TR/TE: 1.9/0.8 ms; flip angle: 40 degrees; GRAPPA) during end-inspiratory and expiratory breathholds. The perfusion parameters pulmonary blood flow (PBF), pulmonary blood volume (PBV), and mean transit time (MTT) were calculated using the indicator dilution theory. As a reference method, end-inspiratory and expiratory phase-contrast (PC) MRI of the pulmonary arterial blood flow (PABF) was performed. RESULTS:There was a statistically significant increase of the PBF (delta = 182 mL/100 mL/min), PBV (delta = 12 mL/100 mL), and PABF (delta = 0.5 L/min) between inspiratory and expiratory breathhold measurements (P < 0.0001). Also, the MTT was significantly shorter (delta = -0.5 sec) at expiratory breathhold (P = 0.03). Inspiratory PBF and PBV showed a moderate correlation (r = 0.72 and 0.61, P < or = 0.008) with inspiratory PABF. CONCLUSION:Pulmonary perfusion during breathhold depends on the inspiratory level. Higher perfusion is observed at expiratory breathhold.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Fink C,Ley S,Risse F,Eichinger M,Zaporozhan J,Buhmann R,Puderbach M,Plathow C,Kauczor HUdoi
10.1097/01.rli.0000149252.42679.78keywords:
subject
Has Abstractpub_date
2005-02-01 00:00:00pages
72-9issue
2eissn
0020-9996issn
1536-0210pii
00004424-200502000-00003journal_volume
40pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199507000-00004
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abstract:RATIONALE AND OBJECTIVES:To compare gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for magnetic resonance imaging of the liver. METHODS:The contrast agent Gd-BOPTA or Gd-DTPA was administered at a dose of 0.1 mmol/kg to 257 patients suspected of having malignant liver tumors. Dynamic phase ...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004424-200111000-00002
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abstract::Using real-time ultrasound, the motions of the tongue, hyoid bone, and larynx were monitored and timed during swallowing in ten normal subjects. A well-defined propulsive wave of the tongue was observed during swallowing a 5-cc water bolus. The body of the hyoid bone was identified on the ultrasound scan as a high ech...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198403000-00003
更新日期:1984-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine to what degree current compressed sensing methods are capable of accelerating clinical magnetic resonance neuroimaging sequences. METHODS:Two 2-dimensional clinical sequences were chosen for this study because of their long scan times. A pilot study was used to establish ...
journal_title:Investigative radiology
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doi:10.1097/RLI.0b013e31828a012d
更新日期:2013-09-01 00:00:00
abstract::The microangiographic anatomy of the cat's eye is presented. The characteristic vascular pattern of each of the three distinct circulations, retinal choroidal, and ciliary is described and illustrated. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197501000-00007
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The ...
journal_title:Investigative radiology
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doi:10.1097/RLI.0b013e318190fbd2
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abstract::An isotopic radiation source 125I was investigated for use in soft tissue radiaography, with particular attention to possible use in mammography for mass screening. Film sensitivities, exposure rates, absorbed doeses, contrast and resolution were determined, and compared to conventional x-ray units. It was found that ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197509000-00007
更新日期:1975-09-01 00:00:00
abstract::An ultrasound phantom was constructed simulating fetal femurs in amniotic fluid. Bones of 26, 36, 50, 58, and 70 mm, representative of gestational ages ranging from 17 to 36 weeks, were scanned with mechanical sector, phased sector, and linear array systems (ATL, Diasonics, Acuson, and GE). Measurements were made with...
journal_title:Investigative radiology
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doi:10.1097/00004424-198505000-00016
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abstract:RATIONALE AND OBJECTIVES:The authors differentiate breast lesions on sonography by measurements in two compression states that are perpendicular to each other. METHODS:Diameters of 100 breast lesions were measured preoperatively under lateromedial and craniocaudal compression with a new sonographic method. This method...
journal_title:Investigative radiology
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doi:10.1097/00004424-199607000-00003
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198505000-00003
更新日期:1985-05-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/00004424-198105000-00016
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doi:10.1097/00004424-199505000-00001
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pub_type: 杂志文章
doi:10.1097/00004424-199302000-00009
更新日期:1993-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...
journal_title:Investigative radiology
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doi:10.1097/00004424-199401000-00012
更新日期:1994-01-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/00004424-199305000-00001
更新日期:1993-05-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00058
更新日期:1988-09-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199112000-00007
更新日期:1991-12-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/00004424-199911000-00004
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journal_title:Investigative radiology
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pub_type: 杂志文章,评审
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journal_title:Investigative radiology
pub_type: 杂志文章
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更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/RLI.0000000000000381
更新日期:2017-10-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2006-09-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199611000-00003
更新日期:1996-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
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journal_title:Investigative radiology
pub_type: 杂志文章,评审
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更新日期:2004-11-01 00:00:00
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更新日期:2010-03-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
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