First-pass evaluation of myocardial output during dipyridamole stress using turbo-FLASH magnetic resonance imaging.

Abstract:

RATIONALE AND OBJECTIVES:This study evaluated the value of dynamically enhanced fast low-angle shot (FLASH) magnetic resonance (MR) imaging in measuring cardiac output with and without dipyridamole pharmacological stress. METHODS:Ten subjects underwent rest and stress MR imaging. Rest images were acquired using electrocardiogram gated MR (turbo-FLASH: repetition time = 6 mseconds; echo time = 12 mseconds; flip angle = 12 degrees, inversion time = 100) 10 to 45 seconds after intravenous bolus of 0.04 mmol/kg gadolinium (Gd)-DTPA using a Siemens 1.0-tesla Magnetom SP. Stress was induced within the MR imaging scanner with 0.56 mg/kg dipyridamole over 4 minutes with stress MR images obtained after a second bolus of Gd-DTPA in exactly the same position and time intervals. Cardiac output was calculated with a least squares error analysis before and after dipyridamole stress for the left and right ventricles in all 10 patients, and comparison was made with cardiac output by Fick dilution technique during cardiac catheterization in seven patients. RESULTS:This MR analysis methodology shows reasonable correlation (r = 0.953) between left ventricular and right ventricular cardiac output with no effect on cardiac output during immediate dipyridamole stress. Fick dilution studies demonstrated a correlation of 0.96. CONCLUSIONS:Turbo-FLASH MR can demonstrate time-activity curves and cardiac output calculations consistent with theoretical predictions.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Tello R,Hartnell GG,Hill TC,Cerel A,Finn JP,Kamalesh M,Cohen M,Lewis S

doi

10.1097/00004424-199611000-00003

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

690-5

issue

11

eissn

0020-9996

issn

1536-0210

journal_volume

31

pub_type

杂志文章
  • Quantification of roughness of calcific deposits in computed tomography scans of human coronary arteries.

    abstract:OBJECTIVES:The incidence of coronary artery disease has been shown to be greater in patients with calcific deposits than in those without. It has been suggested that the pattern of distribution of coronary calcific deposits within coronary arteries is of greater predictive value for acute coronary events than the overa...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3180cc2041

    authors: Wilner WT,Mazraeshahi RM,Aboshady I,Bodmann BG,Papadakis M,Kouri D,Conyers JL,Cherukuri P,Vela D,Gladish G,Gavish L,Cody DD,Frazier L,Lukovenkov S,Madjid M,Zarrabi A,Ahmed A,Willerson JT,Casscells SW,Gertz SD

    更新日期:2007-11-01 00:00:00

  • Correlation of flow velocity measurements by magnetic resonance phase contrast imaging and intravascular Doppler ultrasound.

    abstract:RATIONALE AND OBJECTIVES:The authors compare the magnetic resonance (MR) phase contrast flow velocity measurements in varying concentric stenoses with invasive measurements obtained with a Doppler guidewire. METHODS:Flow velocity measurements were obtained using a calibrated 0.018 inch 12 MHz Doppler guidewire and a 1...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199808000-00001

    authors: Hoppe M,Heverhagen JT,Froelich JJ,Kunisch-Hoppe M,Klose KJ,Wagner HJ

    更新日期:1998-08-01 00:00:00

  • Identifying tumor vascular permeability heterogeneity with magnetic resonance imaging contrast agents.

    abstract:RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200204000-00003

    authors: Aref M,Brechbiel M,Wiener EC

    更新日期:2002-04-01 00:00:00

  • Phlebography. Survey and present state.

    abstract::Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented. ...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Enge I

    更新日期:1985-01-01 00:00:00

  • Stability of MRI paramagnetic contrast media: a proton relaxometric protocol for transmetallation assessment.

    abstract:RATIONALE AND OBJECTIVES:The suitability of paramagnetic complexes as magnetic resonance contrast agents depends on various factors such as their relaxivity, stability, selectivity, and the inertness toward transmetallation by endogenous ions. The transmetallation of a series of 18 gadolinium complexes by the Zn2+ ion ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-200102000-00008

    authors: Laurent S,Elst LV,Copoix F,Muller RN

    更新日期:2001-02-01 00:00:00

  • Renal effects of bicarbonate versus saline infusion for iso- and lowosmolar contrast media in rats.

    abstract:OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31822311a9

    authors: Ladwig M,Flemming B,Seeliger E,Sargsyan L,Persson PB

    更新日期:2011-11-01 00:00:00

  • Contrast-enhanced MRI of tumors. Comparison of Gd-DTPA and a macromolecular agent.

    abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198908000-00007

    authors: Wikström MG,Moseley ME,White DL,Dupon JW,Winkelhake JL,Kopplin J,Brasch RC

    更新日期:1989-08-01 00:00:00

  • Influence of clinical history upon detection of nodules and other lesions.

    abstract::The authors reexamined a suspected difference in the effects of clinical information upon detection of nodules vs. more diverse lesions by directly incorporating classification specificity into detection ROC analysis. Categorical prompts, correct for specific abnormalities, led to detection superior to unprompted read...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198801000-00011

    authors: Berbaum KS,Franken EA Jr,Dorfman DD,Barloon TJ

    更新日期:1988-01-01 00:00:00

  • Dynamic contrast-enhanced ultrasound for assessment of skeletal muscle microcirculation in peripheral arterial disease.

    abstract:OBJECTIVE:: This feasibility study was performed to assess whether dynamic contrast-enhanced ultrasound (CEUS) and transient arterial occlusion are able to detect alterations in the microvascular perfusion and arterial perfusion reserve in patients suffering from peripheral arterial disease (PAD) in comparison with hea...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182183a77

    authors: Amarteifio E,Weber MA,Wormsbecher S,Demirel S,Krakowski-Roosen H,Jöres A,Braun S,Delorme S,Böckler D,Kauczor HU,Krix M

    更新日期:2011-08-01 00:00:00

  • Computed tomography of the normal radioulnar joints.

    abstract::Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198311000-00012

    authors: Cone RO,Szabo R,Resnick D,Gelberman R,Taleisnik J,Gilula LA

    更新日期:1983-11-01 00:00:00

  • Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping.

    abstract:OBJECTIVE:To evaluate the effectiveness of a dual magnetic resonance-near infrared fluorescence optical imaging agent, poly(l-glutamic acid)-DTPA-Gd-NIR813, for both preoperative and intraoperative visualization and characterization of sentinel lymph nodes (SLN) in mice. MATERIALS AND METHODS:Poly(L-glutamic acid) was...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31804f5a79

    authors: Melancon MP,Wang Y,Wen X,Bankson JA,Stephens LC,Jasser S,Gelovani JG,Myers JN,Li C

    更新日期:2007-08-01 00:00:00

  • A review of the toxicity of nonionic contrast agents in children.

    abstract:OBJECTIVES:The safety of nonionic contrast agents with that of ionic iodinated contrast agents in children is compared. METHODS:A comprehensive literature search was conducted to identify all publications on the safety profile of nonionic contrast agents administered intravenously to children. This information was com...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-199311001-00027

    authors: Cohen MD

    更新日期:1993-11-01 00:00:00

  • Prediction of antiangiogenic treatment efficacy by iron oxide enhanced parametric magnetic resonance imaging.

    abstract:RATIONALE AND OBJECTIVES:Tools for monitoring modern target-specific antiangiogenic and antivascular therapies are highly desirable because treatment strategies are time consuming, expensive, and yet sometimes ineffective. Therefore, the aim of this experimental study was to evaluate the predictive value of steady-stat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3180d5cbd9

    authors: Persigehl T,Matuszewski L,Kessler T,Wall A,Meier N,Ebert W,Berdel WE,Heindel W,Mesters R,Bremer C

    更新日期:2007-12-01 00:00:00

  • The pediatric tracheostomy: III). An appraisal of xerography.

    abstract::Comparatively new in the roentgen evaluation of infants and children, xerography would appear to be ideal for portraying the pediatric airway. Since the radiation dose of xerography is higher than conventional radiography, its image quality is the subject of careful scrutiny in a pediatric setting here described in 23...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197807000-00002

    authors: Scott JR,Kramer SS,Griscom NT

    更新日期:1978-07-01 00:00:00

  • Radiation hormesis. Its emerging significance in medical practice.

    abstract::Because of the strong scientific evidence in support of radiation hormesis, we can no longer ignore this concept. There is, however, need for additional, carefully documented investigations in selected biological systems exposed to LLIR if the matter of radiation hormesis is to be settled once and for all. This need s...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:

    authors: Loken MK,Feinendegen LE

    更新日期:1993-05-01 00:00:00

  • Ultrasound-guided, percutaneous cryotherapy of small (< or = 15 mm) breast cancers.

    abstract:RATIONALE AND OBJECTIVE:The purpose of this study was to investigate the feasibility, efficacy, and safety of ultrasound-guided percutaneous cryotherapy of stage T1 breast cancers. MATERIALS AND METHODS:Thirty patients with biopsy-confirmed breast cancers with tumor diameters of 15 mm or smaller (range, 5-15 mm; media...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000166935.56971.ff

    authors: Pfleiderer SO,Marx C,Camara O,Gajda M,Kaiser WA

    更新日期:2005-07-01 00:00:00

  • Evaluation of normal prostate tissue, chronic prostatitis, and prostate cancer by quantitative perfusion analysis using a dynamic contrast-enhanced inversion-prepared dual-contrast gradient echo sequence.

    abstract:OBJECTIVE:To quantify independent pharmacokinetic parameters for differentiation of prostate pathology. MATERIAL AND METHODS:Twenty-seven patients with biopsy-proven prostate cancer (PSA: 1.4-16.1 ng/mL) underwent magnetic resonance imaging with a new dynamic contrast-enhanced, inversion-prepared dual-contrast gradien...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31816b2f63

    authors: Franiel T,Lüdemann L,Rudolph B,Rehbein H,Staack A,Taupitz M,Prochnow D,Beyersdorff D

    更新日期:2008-07-01 00:00:00

  • Time continuous tracking and segmentation of cardiovascular magnetic resonance images using multidimensional dynamic programming.

    abstract::In this article, we propose a semiautomatic method for time-continuous contour detection in all phases of the cardiac cycle in magnetic resonance sequences. The method is based on multidimensional dynamic programming. After shape parameterization, cost hypercubes are filled with image-feature derived cost function val...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000194070.88432.24

    authors: Uzümcü M,van der Geest RJ,Swingen C,Reiber JH,Lelieveldt BP

    更新日期:2006-01-01 00:00:00

  • Diffusivity- and T2 imaging at 3 Tesla for the detection of degenerative changes in human-excised tissue with high resolution: atherosclerotic arteries.

    abstract:RATIONALE AND OBJECTIVES:We investigated whether it is possible to investigate degenerative changes in human tissue on a sub-100-microm resolution scale not only on special high-field small-bore MR-microscopy systems but also on a 3T whole-body MR-scanner. METHODS:Spin-spin relaxation, proton density, and diffusion mi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.RLI.0000068620.17569.83

    authors: Berg A,Sailer J,Rand T,Moser E

    更新日期:2003-07-01 00:00:00

  • Evaluation of noninvasive follow-up methods for the detection of intracranial in-stent restenosis: a phantom study.

    abstract:OBJECTIVES:Intra-arterial digital subtraction angiography (IA-DSA), an invasive procedure, is the current reference examination after percutaneous transluminal angioplasty and stenting for the detection of in-stent restenosis (ISR). In this phantom study, we evaluated flat-panel angiographic computed tomography after i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e318276db43

    authors: Psychogios MN,Schramm P,Amelung N,Pilgram-Pastor SM,Gröschel K,Wasser K,Frölich AM,Mohr A,Knauth M

    更新日期:2013-02-01 00:00:00

  • Hepatic kinetics and magnetic resonance imaging of gadolinium-EOB-DTPA in dogs.

    abstract:RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199604000-00005

    authors: Benness G,Khangure M,Morris I,Warwick A,Burrows P,Vogler H,Weinmann HJ

    更新日期:1996-04-01 00:00:00

  • Protective effects of corticosteroids in contrast material anaphylaxis.

    abstract::A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours be...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00004424-198809001-00035

    authors: Lasser EC,Berry CC,Talner LB,Santini LC,Lang EK,Gerber FH,Stolberg HO

    更新日期:1988-09-01 00:00:00

  • Pharmacokinetics and safety of gadobutrol-enhanced magnetic resonance imaging in pediatric patients.

    abstract:OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181bfe2d2

    authors: Hahn G,Sorge I,Gruhn B,Glutig K,Hirsch W,Bhargava R,Furtner J,Born M,Schröder C,Ahlström H,Kaiser S,Moritz JD,Kunze CW,Shroff M,Stokland E,Trnkova ZJ,Schultze-Mosgau M,Reif S,Bacher-Stier C,Mentzel HJ

    更新日期:2009-12-01 00:00:00

  • Semiquantitative assessment of myocardial perfusion using magnetic resonance imaging: evaluation of appropriate thresholds and segmentation models.

    abstract:RATIONALE AND OBJECTIVES:The aim of the study was to determine optimal thresholds for semiquantitative perfusion parameters and to evaluate the influence of different segmentation models in detecting malperfused regions. MATERIAL AND METHODS:In 6 healthy subjects and 13 patients with coronary artery disease, contrast-...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000133816.83192.38

    authors: Fenchel M,Kramer U,Helber U,Stauder NI,Franow A,Claussen CD,Miller S

    更新日期:2004-09-01 00:00:00

  • High-Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted Images: Evaluation of the Macrocyclic Gadolinium-Based Contrast Agent Gadobutrol.

    abstract:OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000227

    authors: Radbruch A,Weberling LD,Kieslich PJ,Hepp J,Kickingereder P,Wick W,Schlemmer HP,Bendszus M

    更新日期:2015-12-01 00:00:00

  • Adenosine-stress dynamic myocardial CT perfusion imaging: initial clinical experience.

    abstract:OBJECTIVE:To evaluate the feasibility of adenosine-stress dynamic myocardial volume perfusion imaging with second generation dual source computed tomography (CT) for the qualitative and quantitative assessment of myocardial blood flow (MBF) compared with stress perfusion and viability magnetic resonance imaging (MRI). ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181dfa2f2

    authors: Bastarrika G,Ramos-Duran L,Rosenblum MA,Kang DK,Rowe GW,Schoepf UJ

    更新日期:2010-06-01 00:00:00

  • Robot-assisted biopsy using computed tomography-guidance: initial results from in vitro tests.

    abstract:PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000155285.05672.cf

    authors: Kettenbach J,Kronreif G,Figl M,Fürst M,Birkfellner W,Hanel R,Ptacek W,Bergmann H

    更新日期:2005-04-01 00:00:00

  • Evaluation of Gd-EOB-DTPA uptake in a perfused and isolated mouse liver model: correlation between magnetic resonance imaging and monochromatic quantitative computed tomography.

    abstract:OBJECTIVES:The aim of this work was to quantitatively evaluate the pharmacokinetic pattern of Gd-EOB-DTPA in a model of isolated and perfused mouse liver by using magnetic resonance imaging (MRI) and monochromatic quantitative computed tomography (MQCT). MATERIALS AND METHODS:For MQCT, perfusions were realized with th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000174474.43772.58

    authors: Segers J,Le Duc G,Laumonier C,Troprès I,Elst LV,Muller RN

    更新日期:2005-09-01 00:00:00

  • Segmentation-based attenuation correction in positron emission tomography/magnetic resonance: erroneous tissue identification and its impact on positron emission tomography interpretation.

    abstract:OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000131

    authors: Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

    更新日期:2015-05-01 00:00:00

  • Comparison of left ventricular ejection fraction and regional contractility fraction pre and post coronary angiography.

    abstract::Thirty patients [four normals, eight with mild and 18 with severe coronary artery disease (CAD)] were studied to evaluate left ventricular function type and post coronary angiography. The end diastolic volume (EDV), end systolic volume (ESV), ejection fraction (EF) and the regional contractility fractions (RCF) of eig...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197603000-00009

    authors: Sos TA,Baltaxe HA

    更新日期:1976-03-01 00:00:00