Evaluation of normal prostate tissue, chronic prostatitis, and prostate cancer by quantitative perfusion analysis using a dynamic contrast-enhanced inversion-prepared dual-contrast gradient echo sequence.

abstract：RATIONALE AND OBJECTIVES:The suitability of paramagnetic complexes as magnetic resonance contrast agents depends on various factors such as their relaxivity, stability, selectivity, and the inertness toward transmetallation by endogenous ions. The transmetallation of a series of 18 gadolinium complexes by the Zn2+ ion ...

journal_title：Investigative radiology

authors： Laurent S,Elst LV,Copoix F,Muller RN

更新日期：2001-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Laser-induced interstitial thermotherapy (LITT) may become an attractive modality for minimally invasive tumor therapy. Magnetic resonance imaging (MRI) could be used to assist this procedure. METHODS:A T1-weighted turbo fast low-angle shot (FLASH) sequence for on-line monitoring of the laser-...

journal_title：Investigative radiology

authors： Gewiese B,Beuthan J,Fobbe F,Stiller D,Müller G,Böse-Landgraf J,Wolf KJ,Deimling M

更新日期：1994-03-01 00:00:00

abstract：PURPOSE:The aim was to investigate the feasibility and image quality of prospective respiratory gating for 3-D computed tomography (CT) of the lung. MATERIAL AND METHODS:Eight anesthetized pigs underwent prospectively gated multidetector computed tomography using 2 devices: a charge-coupled device (CCD) camera and a l...

journal_title：Investigative radiology

authors： Zaporozhan J,Ley S,Unterhinninghofen R,Saito Y,Fabel-Schulte M,Keller S,Szabo G,Kauczor HU

更新日期：2006-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Because of the greatly increased cost of nonionic, low-osmolar contrast material, some practitioners reserve its use for patients at high risk for an adverse contrast reaction. The authors attempt to evaluate the proportion of low-risk outpatients--when offered a choice between the more expensi...

journal_title：Investigative radiology

authors： Hopper KD,Matthews YL

更新日期：1993-04-01 00:00:00

abstract：:The biliary and urinary excretion of sodium tyropanoate (Bilopaque) and sodium ipodate (Oragrafin) were studied in unanesthetized bile-fistula dogs using stepwise, increasing, intravenous infusions of the contrast materials. A constant intravenous infusion of sodium taurocholate was administered at the rate of either ...

journal_title：Investigative radiology

authors： Berk RN,Loeb PM,Cobo-Frenkel A,Barnhart JL

更新日期：1977-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors analyze the origins of the "clotting issue," the controversy that began in the 1980s when contrast media, once perceived as good flushing agents for catheters because of their assumed anticoagulant properties, came under attack for allegedly causing thromboembolism. Laboratory studi...

journal_title：Investigative radiology

authors： Dawson P,Cousins C,Bradshaw A

更新日期：1993-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:It is widely believed that down-sizing catheters, and possibly needles, will decrease damage to the entry vessel in the performance of angiography. The purposes of this in vitro experiment are to determine if smaller needles produce less arterial wall damage than larger needles and to assess th...

journal_title：Investigative radiology

authors： Smith DC,Hamlin JA,Jensen DA,Pappas JM,Westengard JC,Saukel GW

更新日期：1992-10-01 00:00:00

abstract：:We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...

journal_title：Investigative radiology

authors： Hayakawa K,Yamashita K

更新日期：1989-04-01 00:00:00

abstract：:Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...

journal_title：Investigative radiology

authors： Burbank FH,Thompson WM

更新日期：1986-03-01 00:00:00

abstract：:The purpose of our investigation was to determine whether iopanoyl glucuronide, the major metabolite of iopanoic acid (Telepaque), undergoes hydrolysis by bacterial beta-glucuronidase in dogs. The conjugated compound was identified and quantitated by elemental analysis, fluorescent excitation analysis, thin-layer chro...

journal_title：Investigative radiology

authors： Thoeni RF,Goldberg HI,Moss AA,Lin SK,Brito AC

更新日期：1978-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Emulsions of perfluorocarbons (PFCs) have been tested as blood substitutes. However, evidence exists that there is long-term retention of some PFCs by the organs of the reticuloendothelial system (RES). The authors investigate organ retention of the blood substitute component, perfluorotripropy...

journal_title：Investigative radiology

authors： Meyer KL,Carvlin MJ,Mukherji B,Sloviter HA,Joseph PM

更新日期：1992-08-01 00:00:00

abstract：:A radiographic method for use in the closed-chest dog is described which allows the quantitation of segmental mechanical performance. Previous work has shown that the area of the pressure-length loop (an approximation of a stress-strain integral) is a useful measure of the mechanical work performed by a segment of myo...

journal_title：Investigative radiology

authors： Ringertz HG,Carlsson E,Tyberg JV

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：:A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...

journal_title：Investigative radiology

authors： Powers TA,Rees RS,Bowen RD

更新日期：1983-07-01 00:00:00

abstract：:A high-speed computed tomography (CT) scanner was used for measuring flow in a phantom and in the common carotid arteries of six dogs. The general ability of the scanner to assess flow using contrast media boluses was tested with the phantom. The validated simple concept was then used in the animals. The carotid blood...

journal_title：Investigative radiology

authors： Ringertz HG,Jaschke W,Sievers R,Lipton MJ

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...

journal_title：Investigative radiology

authors： Hellbach K,Yaroshenko A,Willer K,Pritzke T,Baumann A,Hesse N,Auweter S,Reiser MF,Eickelberg O,Pfeiffer F,Hilgendorff A,Meinel FG

更新日期：2016-10-01 00:00:00

abstract：:The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

journal_title：Investigative radiology

authors： Roberts JG,DiTomasso E,Webber CE

更新日期：1982-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vasoconstriction of the renal arteries is frequently considered as a crucial factor for radiocontrast-induced nephropathy. A direct effect of iodinated radiographic contrast medium (RCM) on vascular smooth muscle is supposed to be one component of the vascular response. We studied the effec...

journal_title：Investigative radiology

authors： Uder M,Humke U,Pahl M,Jansen A,Utz J,Kramann B

更新日期：2002-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

journal_title：Investigative radiology

authors： Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The purpose of this study was to evaluate the effects of variation in design parameters on the resultant radial force. We evaluated the influence of wire gauge, leg length, and number of bends on the radial force produced by z stents and compared these with radial forces produced by commercial s...

journal_title：Investigative radiology

authors： Snowhill PB,Nosher JL,Siegel RL,Silver FH

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:: This feasibility study was performed to assess whether dynamic contrast-enhanced ultrasound (CEUS) and transient arterial occlusion are able to detect alterations in the microvascular perfusion and arterial perfusion reserve in patients suffering from peripheral arterial disease (PAD) in comparison with hea...

journal_title：Investigative radiology

authors： Amarteifio E,Weber MA,Wormsbecher S,Demirel S,Krakowski-Roosen H,Jöres A,Braun S,Delorme S,Böckler D,Kauczor HU,Krix M

更新日期：2011-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:New targeted microbubbles directed to the GPIIb IIIa receptor have been developed. The objective was to determine whether targeting microbubbles to clots would enhance ultrasound imaging. Systematic studies were designed to determine whether in vitro methodology is an acceptable predictor of in...

journal_title：Investigative radiology

authors： Schumann PA,Christiansen JP,Quigley RM,McCreery TP,Sweitzer RH,Unger EC,Lindner JR,Matsunaga TO

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

journal_title：Investigative radiology

authors： Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Dynamic ventilation (3)He-MRI is a new method to assess pulmonary gas inflow. As differing airway diameters throughout the ventilatory cycle can influence gas inflow this study intends to investigate the influence of volume and timing of a He gas bolus with respect to the beginning of the tidal volume on insp...

journal_title：Investigative radiology

authors： Gast KK,Hawig K,Windirsch M,Markstaller K,Schreiber WG,Schmiedeskamp J,Düber C,Kauczor HU,Heussel CP

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the prognostic utility of a staging system using magnetic resonance imaging (MRI) with the seventh American Joint Committee on Cancer (AJCC) staging system in patients with hepatocellular carcinoma (HCC) who underwent hepatic resection. MATERIALS AND METHODS:A total of 1...

journal_title：Investigative radiology

authors： An C,Choi GH,Lee HS,Kim MJ

更新日期：2012-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00

abstract：:The microangiographic anatomy of the cat's eye is presented. The characteristic vascular pattern of each of the three distinct circulations, retinal choroidal, and ciliary is described and illustrated. ...

journal_title：Investigative radiology

authors： Rothman SL,Kier EL,Deuker DK

更新日期：1975-01-01 00:00:00

abstract：:Gelatin encapsulated nitrogen microbubbles were effective ultrasonic contrast agents in in vitro phantom and in vivo rabbit V2 carcinoma studies. Intra-arterial injection of 80-micrometer gelatin encapsulated nitrogen microbubbles appeared to improve tumor visualization by rim enhancement, which persisted for several ...

journal_title：Investigative radiology

authors： Carroll BA,Turner RJ,Tickner EG,Boyle DB,Young SW

更新日期：1980-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study was devised to develop a method of measuring the acute effects of radiocontrast media on renal function and assessing the relationship of the dose of radiocontrast media infused with the incidence of radiocontrast-induced renal failure. In addition, the drug adenosine phosphate-magne...

journal_title：Investigative radiology

authors： Albert SG,Shapiro MJ,Brown WW,Goodgold H,Zuckerman D,Durham R,Kern M,Fletcher J,Wolverson M,Plummer ES

更新日期：1994-06-01 00:00:00