Development, chemistry, and physical properties of iopamidol and its analogues.

abstract：:The rate at which isotopes descend from the cisterna magna to the lumbar subarachnoid space is highly variable. In monkeys, with and without previous lumbar puncture, transit time was measured. In animals with a previous lumbar puncture, transit times were 10 to 120 minutes; in monkeys without a previous lumbar punctu...

journal_title：Investigative radiology

authors： Lipman B,Palmer D,Noble J,Haughton V,Collier D

更新日期：1988-05-01 00:00:00

abstract：:The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...

journal_title：Investigative radiology

authors： Siegel EL,Bishop MD,Wetzel LH,Anderson WF,McMillan JH

更新日期：1991-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

journal_title：Investigative radiology

authors： Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

更新日期：2001-01-01 00:00:00

abstract：:The problem of inhomogeneous mixing encountered during hepatic artery (HA) chemotherapy infusion was assessed and a practical solution examined. A glass model of the human HA distribution was used to determine mixing homogeneity of low flow (1.4 mL/minute) dye infusion into pulsatile flow (280-300 mL/minute) of a flui...

journal_title：Investigative radiology

authors： Barth KH,Lutz RJ,Kremers PW,Miller DL

更新日期：1988-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

journal_title：Investigative radiology

authors： Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To quantify independent pharmacokinetic parameters for differentiation of prostate pathology. MATERIAL AND METHODS:Twenty-seven patients with biopsy-proven prostate cancer (PSA: 1.4-16.1 ng/mL) underwent magnetic resonance imaging with a new dynamic contrast-enhanced, inversion-prepared dual-contrast gradien...

journal_title：Investigative radiology

authors： Franiel T,Lüdemann L,Rudolph B,Rehbein H,Staack A,Taupitz M,Prochnow D,Beyersdorff D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...

journal_title：Investigative radiology

authors： Tokuda J,Wang Q,Tuncali K,Seethamraju RT,Tempany CM,Schmidt EJ

更新日期：2020-05-01 00:00:00

abstract：:Post-angioplasty restenosis (PARS) in atherosclerotic lesions of medium and small arteries occurs in about one-third of cases in the first year following percutaneous transluminal angioplasty (PTA) (early PARS). PARS includes acute spasm, dissection with reclosure, elastic recoil, fibrocellular proliferative response,...

journal_title：Investigative radiology

authors： Becker GJ,Lee BI,Waller BF,Barry KJ,Kaplan J,Connolly R,Dreesen RG,Nardella P

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVES:Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive tumor with a very low 5-year survival rate of 8%. The aims of this study are to determine reference values and physiologic confounders in healthy pancreas and to assess the diagnostic accuracy of ultrasound time-harmonic elastography (THE) in the d...

journal_title：Investigative radiology

authors： Burkhardt C,Tzschätzsch H,Schmuck R,Bahra M,Jürgensen C,Pelzer U,Hamm B,Braun J,Sack I,Marticorena Garcia SR

更新日期：2020-05-01 00:00:00

abstract：:The efficacy and safety of perfluoroctylbromide as a diagnostic contrast agent for direct lymphography was studied in mongrel dogs. This radiopaque perfluorocarbon has several advantages over Ethiodol. The liquid compound has injection times one-fifth of that required for Ethiodol. When dosages were three to four tim...

journal_title：Investigative radiology

authors： Liebner EJ

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVES:We compared the image quality and diagnostic performance of 2 fat-suppression methods for black-blood T2-weighted fast spin-echo (FSE), which are as follows: (a) short T1 inversion recovery (STIR; FSE-STIR) and (b) spectral adiabatic inversion recovery (SPAIR; FSE-SPAIR), for detection of acute myocardial in...

journal_title：Investigative radiology

authors： Srichai MB,Lim RP,Lath N,Babb J,Axel L,Kim D

更新日期：2013-01-01 00:00:00

abstract：:A method and associated algorithm are presented which allow a simple and accurate determination to be made of the location of small symmetric areas presented in roentgenological images. The method utilizes an operator to visually spot object positions but eliminates the need for critical positoning accuracy on the ope...

journal_title：Investigative radiology

authors： Keller RA,Baily NA

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVES:Magnetic resonance imaging guidance has been sporadically reported for renal tumor cryoablation (CA); therefore, clinical experience with this modality is still limited.The aim of this study is to retrospectively analyze our 10-year experience with renal tumor CA performed on a 1.5 T magnetic resonance imagi...

journal_title：Investigative radiology

authors： Cazzato RL,De Marini P,Leonard-Lorant I,Leclerc L,Auloge P,Tricard T,Dalili D,Garnon J,Lang H,Gangi A

更新日期：2020-09-04 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the effect of contrast dose, use of magnetization transfer (MT), and temporal delay on the visualization of contrast enhancement with gadoteridol (Gd HP-DO3A) in a canine brain abscess model. METHODS:Alpha streptococcus brain abscesses were studied in five dogs at 1.5 tesla...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Kirsch JE

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate accuracy of biliary anatomy depiction and quality of biliary tract visualization of magnetic resonance cholangiography (MRC) at 3.0 T in living potential liver donors (LPLDs). MATERIALS AND METHODS:Our institutional review board approved this study and did not require patient's inf...

journal_title：Investigative radiology

authors： Kim SY,Byun JH,Hong HS,Choi EK,Lee SS,Park SH,Lee MG

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...

journal_title：Investigative radiology

authors： Chaabane L,Soulas EC,Contard F,Salah A,Guerrier D,Briguet A,Douek P

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:As an imaging modality for follow-up during continuous or repeated hepatic arterial infusion chemotherapy using a hepatic intra-arterial indwelling catheter, the usefulness of CT while infusing contrast through the indwelling catheter (reservoir port) was examined. METHODS:Using reservoir ports implanted in ...

journal_title：Investigative radiology

authors： Morimoto M,Satake M,Sekiguchi R,Haruno M,Moriyama N

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the feasibility of the combination of magnetic resonance (MR)-guided biopsy (MRGB) and diagnostic 3T MR imaging in the localization of local recurrence of prostate cancer (PCa) after external beam radiation therapy (EBRT). MATERIALS AND METHODS:Twenty-four consecuti...

journal_title：Investigative radiology

authors： Yakar D,Hambrock T,Huisman H,Hulsbergen-van de Kaa CA,van Lin E,Vergunst H,Hoeks CM,van Oort IM,Witjes JA,Barentsz JO,Fütterer JJ

更新日期：2010-03-01 00:00:00

abstract：:Pyrroxamide [N-(1-hydroxymethyl-2,3-dihydroxypropyl)-2,2,5,5-tetramethyl pyrrolidine-1-oxyl-3-carboxyamide] is a newly tested nonionic monomeric nitroxyl compound with demonstrated effectiveness for MRI contrast enhancement at doses as low as 10(-3) M. Pyrroxamide and its hydroxylamine metabolic derivative were tested...

journal_title：Investigative radiology

authors： Gordon DG,Brasch RC,Ogan MD,Deen D

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess and compare the overall performance, reliability, variability, as well as the accuracy of diffusion tensor imaging (DTI) and fiber tracking metrics, for the muscles of the calf at 3 T and 7 T. MATERIALS AND METHODS:Ten volunteers (5 males; mean age, 29.1 ± 4.7 years), with...

journal_title：Investigative radiology

authors： Giraudo C,Motyka S,Weber M,Feiweier T,Trattnig S,Bogner W

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Intra-arterial digital subtraction angiography (IA-DSA), an invasive procedure, is the current reference examination after percutaneous transluminal angioplasty and stenting for the detection of in-stent restenosis (ISR). In this phantom study, we evaluated flat-panel angiographic computed tomography after i...

journal_title：Investigative radiology

authors： Psychogios MN,Schramm P,Amelung N,Pilgram-Pastor SM,Gröschel K,Wasser K,Frölich AM,Mohr A,Knauth M

更新日期：2013-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...

journal_title：Investigative radiology

authors： Sijens PE,Den Heijer T,De Leeuw FE,De Groot JC,Achten E,Heijboer RJ,Hofman A,Breteler MM,Oudkerk M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...

journal_title：Investigative radiology

authors： Hahn G,Sorge I,Gruhn B,Glutig K,Hirsch W,Bhargava R,Furtner J,Born M,Schröder C,Ahlström H,Kaiser S,Moritz JD,Kunze CW,Shroff M,Stokland E,Trnkova ZJ,Schultze-Mosgau M,Reif S,Bacher-Stier C,Mentzel HJ

更新日期：2009-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors report on the development and preliminary validation of a technique for measuring contrast-to-noise ratio (CNR) at all points along selected vessel segments in the original three-dimensional magnetic resonance angiography (MRA) dataset. METHODS:Contrast-to-noise ratio dependencies ...

journal_title：Investigative radiology

authors： Du Y,Parker DL,Davis WL,Blatter DD

更新日期：1993-11-01 00:00:00

abstract：:Intravenous or intra-aortic injections of meglumine iothalamate in dogs indicate a slightly different tissue distribution and excretory pattern of the meglumine cation and the iothalamate anion. Differences in serum and urinary concentrations of these ions suggest some cellular penetration of the meglumine anion. In a...

journal_title：Investigative radiology

authors： Lasser EC,Lang JH,Hamblin AE,Rosen L

更新日期：1975-07-01 00:00:00

abstract：:We evaluated the density distribution (anterior-posterior) of the right lung in 19 acutely anesthetized supine dogs using computed transmission tomography (CTT). Eleven dogs served as controls, and eight received 0.12 cc/kg of intravenously administered oleic acid. The latter were sequentially imaged over 1 hour. Nine...

journal_title：Investigative radiology

authors： Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

更新日期：1984-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:At many institutions, three-dimensional magnetic resonance imaging (MRI) is routinely used for examination of the knee. Multiplanar reconstruction (MPR) is a method of displaying three-dimensional datasets. The authors assessed the usefulness of MPR for evaluating knee MRI datasets by comparing...

journal_title：Investigative radiology

authors： Gay SB,Chen NC,Burch JJ,Gleason TR,Sagman AM

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the correlation between dynamic gadoxetic acid-enhanced magnetic resonance imaging parameters and specific uptake values (SUVs) derived from ¹⁸fluorodeoxyglucose (¹⁸F-FDG) and ⁶⁸Ga-DOTA-Tyr(3)-octreotate (⁶⁸Ga-DOTATATE) positron emission tomography/computed tomogra...

journal_title：Investigative radiology

authors： Armbruster M,Sourbron S,Haug A,Zech CJ,Ingrisch M,Auernhammer CJ,Nikolaou K,Paprottka PM,Rist C,Reiser MF,Sommer WH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the impact of impaired renal function on gadolinium (Gd) retention in various organs after Gd-based contrast agent injection. MATERIALS AND METHODS:After local animal care and review committee approval, 23 normal mice and 26 with renal failure were divided into 4 tre...

journal_title：Investigative radiology

authors： Kartamihardja AA,Nakajima T,Kameo S,Koyama H,Tsushima Y

更新日期：2016-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00