Effects of iodinated x-ray contrast media on renal epithelial cells in culture.

abstract：:Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...

journal_title：Investigative radiology

authors： LeWinter MM,Pavelec RS

更新日期：1982-09-01 00:00:00

abstract：:Early detection of pancreatic ductal adenocarcinoma (PDAC) represents the most significant step toward the treatment of this aggressive lethal disease. Previously, we engineered a preclinical Thy1-targeted microbubble (MBThy1) contrast agent that specifically recognizes Thy1 antigen overexpressed in the vasculature of...

journal_title：Investigative radiology

authors： Bam R,Daryaei I,Abou-Elkacem L,Vilches-Moure JG,Meuillet EJ,Lutz A,Marinelli ER,Unger EC,Gambhir SS,Paulmurugan R

更新日期：2020-11-01 00:00:00

abstract：:Three methods are presented which provide statistically acceptable estimates of mean transit time of opacified blood during angiography. While the methods vary in precision, the selection of the method appropriate for any particular experimental model depends on the degree of precision required to demonstrate the effe...

journal_title：Investigative radiology

authors： Silverman NR,Rosen L

更新日期：1977-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

journal_title：Investigative radiology

authors： Tweedle MF,Wedeking P,Kumar K

更新日期：1995-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...

journal_title：Investigative radiology

authors： Aguado F,Revilla M,Hernández ER,Villa LF,Rico H

更新日期：1997-01-01 00:00:00

abstract：:Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...

journal_title：Investigative radiology

authors： Berk RN,Barnhart JL,Nazareno G,Witt BL

更新日期：1981-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Hepatocellular carcinomas (HCCs) usually consist of components of different histologic grade. Using surgically resected specimens, the authors obtained high-resolution magnetic resonance (MR) images and studied the relationship between histologic grade of HCCs and MR signal intensity. METHOD:I...

journal_title：Investigative radiology

authors： Inoue E,Kuroda C,Narumi Y,Fujita M,Kadota T,Kuriyama K,Yoshioka H,Ishiguro S,Sasaki Y,Imaoka S

更新日期：1993-08-01 00:00:00

abstract：:The authors present a numerical deconvolution technique to compensate for image degrading effects caused by scattered photons in radiographic chest images. Fourier transform techniques are used to deconvolve a shift invariant model of the two dimensional point spread response functions of the scattered radiation. This...

journal_title：Investigative radiology

authors： Floyd CE,Beatty PT,Ravin CE

更新日期：1989-01-01 00:00:00

abstract：:Thirty patients [four normals, eight with mild and 18 with severe coronary artery disease (CAD)] were studied to evaluate left ventricular function type and post coronary angiography. The end diastolic volume (EDV), end systolic volume (ESV), ejection fraction (EF) and the regional contractility fractions (RCF) of eig...

journal_title：Investigative radiology

authors： Sos TA,Baltaxe HA

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVES:X-ray computed tomography (CT) using phase contrast can provide images with greatly enhanced soft-tissue contrast in comparison to conventional attenuation-based CT. We report on the first scan of a human specimen recorded with a phase-contrast CT system based on an x-ray grating interferometer and a convent...

journal_title：Investigative radiology

authors： Donath T,Pfeiffer F,Bunk O,Grünzweig C,Hempel E,Popescu S,Vock P,David C

更新日期：2010-07-01 00:00:00

abstract：:The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...

journal_title：Investigative radiology

authors： Cox GG,Templeton AW,Anderson WH,Cook LT,Hensley KS,Dwyer SJ 3rd

更新日期：1986-02-01 00:00:00

abstract：:A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours be...

journal_title：Investigative radiology

authors： Lasser EC,Berry CC,Talner LB,Santini LC,Lang EK,Gerber FH,Stolberg HO

更新日期：1988-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Optimal dose schedules and total dose of ionizing radiation for human central nervous system malignancy are not known. An animal model has been developed for the investigation of rat central nervous system response to proton irradiation using magnetic resonance imaging (MRI). A clinical MRI dev...

journal_title：Investigative radiology

authors： Kennedy AS,Archambeau JO,Archambeau MH,Holshouser B,Thompson J,Moyers M,Hinshaw D Jr,Slater JM

更新日期：1995-04-01 00:00:00

abstract：:The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...

journal_title：Investigative radiology

authors： Fajardo LL,Yoshino MT,Seeley GW,Hunt R,Hunter TB,Friedman R,Cardenas D,Boyle R

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the influence of different weighting factors on contrast enhancement, signal-to-noise ratio (SNR), and image quality in image fusion in dual energy computed tomography (DECT) angiography. MATERIAL AND METHODS:Fifteen patients underwent a CT angiography of the aorta with ...

journal_title：Investigative radiology

authors： Behrendt FF,Schmidt B,Plumhans C,Keil S,Woodruff SG,Ackermann D,Mühlenbruch G,Flohr T,Günther RW,Mahnken AH

更新日期：2009-01-01 00:00:00

abstract：:Video dilution technique (VDT) is currently performed in conjunction with routine cerebral angiography to determine carotid blood flow in humans. Preliminary results indicate that the blood flows (as a percentage of cardial output) of the common, internal, and external carotid arteries are 8.5%, 5.5%, and 3.0%, respec...

journal_title：Investigative radiology

authors： Lantz BM,Dublin AB,McGahan JP,Link DP

更新日期：1981-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:High signal intensity in the basal ganglia on T1-weighted MR imaging has been reported in chronic manganese (Mn) poisoning. However, the exact meaning of the high signal intensity remains unclear: does it result from Mn itself, secondary pathologic changes of the brain tissue, or both? The goal...

journal_title：Investigative radiology

authors： Kim SH,Chang KH,Chi JG,Cheong HK,Kim JY,Kim YM,Han MH

更新日期：1999-06-01 00:00:00

abstract：:A technique to measure absolute arterial blood flow in ml/min has been developed utilizing software programs with high-speed digital recording for the off-line analysis of intra-arterial injections of contrast medium. Measurements of pulsatile flow in a phantom for a physical flow model showed that calculations with t...

journal_title：Investigative radiology

authors： Forbes G,Gray JE,Felmlee JP

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the use of dielectric pads for improving high spatial resolution imaging of the inner ear at 7 T. MATERIALS AND METHODS:Two sets of dielectric pads were designed using electromagnetic simulations and implemented using a deuterated suspension of barium titanate. Th...

journal_title：Investigative radiology

authors： Brink WM,van der Jagt AM,Versluis MJ,Verbist BM,Webb AG

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...

journal_title：Investigative radiology

authors： Diekmann F,Diekmann S,Jeunehomme F,Muller S,Hamm B,Bick U

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:Over the recent years, there have been increasing concerns that exposure to gadolinium-based contrast agents (GBCAs) may be associated with retention of Gd within the skin, bones, and solid organs in patients with normal renal function, although the clinical implications of this deposition remain to be estab...

journal_title：Investigative radiology

authors： Layne KA,Wood DM,Dixon-Zegeye M,Archer JRH,Raja K,Dargan PI

更新日期：2020-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study was to determine whether cerebral fat embolism demonstrated reversible or irreversible findings in magnetic resonance (MR) imaging over time and to compare the features in MR images with histologic findings in a cat model. MATERIALS AND METHODS:MR images were obtained...

journal_title：Investigative radiology

authors： Kim HJ,Lee CH,Lee SH,Moon TY

更新日期：2003-10-01 00:00:00

abstract：:Multiple intravenous injections of contrast media are used in radiology, but information regarding corresponding changes in the serum iodine concentrations and osmolality is lacking. We measured the changes in serum iodine concentration and serum osmolality in rabbits after a series of intravenous injections of contra...

journal_title：Investigative radiology

authors： Rubin DI,Kido DK,Morris TW,Fischer HW

更新日期：1987-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Air microemboli may damage the cerebral microvasculature. The aim of this study was to evaluate the safety of ultrasound contrast agents composed of air microspheres with regard to cerebral damage when administered into the arterial system (ie, when not filtered by the capillary system of the l...

journal_title：Investigative radiology

authors： Haggag KJ,Russell D,Walday P,Skiphamn A,Torvik A

更新日期：1998-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...

journal_title：Investigative radiology

authors： Aref M,Brechbiel M,Wiener EC

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of nephrogenic systemic fibrosis (NSF) in patients with chronic kidney disease (CKD) who have received gadopentetate dimeglumine. MATERIALS AND METHODS:We retrospectively studied all patients who underwent contrast-enhanced magnetic resonance imagings (CE-MRIs) between January 1, ...

journal_title：Investigative radiology

authors： Hope TA,Herfkens RJ,Denianke KS,LeBoit PE,Hung YY,Weil E

更新日期：2009-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the feasibility of mechanical thrombectomy in occluded hemodialysis access shunts by using a newly developed 5F pigtail rotation catheter. METHODS:Thrombosed hemodialysis access shunts were simulated by clotted bovine blood in silicone tubing (diameter 6 mm). After retrograde and a...

journal_title：Investigative radiology

authors： Wildberger J,Schmitz-Rode T,Wein BB,Günther RW

更新日期：1999-07-01 00:00:00

abstract：:For magnetic resonance, the established class of intravenous contrast media is the gadolinium-based contrast agents. In the 3 decades since initial approval, these have proven in general to be very safe for human administration. However, in 2006, a devastating late adverse reaction to administration of the less stable...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2017-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Very small dextran-coated magnetite particles were developed. These particles can be used either as immunospecific contrast agents for MRI by coupling to antibodies or as an interstitial contrast agent. METHODS:The particles were synthesized from iron chloride/dextran solutions. Size was evalu...

journal_title：Investigative radiology

authors： Grimm J,Karger N,Lüsse S,Winoto-Morbach S,Krisch B,Müller-Hülsbeck S,Heller M

更新日期：2000-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gray scale and power Doppler sonography are commonly used to evaluate cervical lymph nodes. This study was undertaken to identify which of the features used in ultrasound of cervical lymph nodes is readily applicable in routine clinical practice. METHODS:Two hundred and eight-six patients diag...

journal_title：Investigative radiology

authors： Ahuja A,Ying M

更新日期：2002-06-01 00:00:00