Application of direct cannulation and injection lymphangiography to the study of the canine cardiac and pulmonary efferent mediastinal lymphatics.

abstract：RATIONALE AND OBJECTIVES:Bolus injection of iodinated contrast media has been observed to alter myocardial mechanical function, but the consequences on cellular metabolism are poorly documented. Modifications of metabolic parameters (intracellular pH as well as adenosine triphosphate [ATP], phosphocreatine, and inorgan...

journal_title：Investigative radiology

authors： Goossens A,Vander Elst L,Van Haverbeke Y,Muller RN

更新日期：1995-01-01 00:00:00

abstract：:The problem of inhomogeneous mixing encountered during hepatic artery (HA) chemotherapy infusion was assessed and a practical solution examined. A glass model of the human HA distribution was used to determine mixing homogeneity of low flow (1.4 mL/minute) dye infusion into pulsatile flow (280-300 mL/minute) of a flui...

journal_title：Investigative radiology

authors： Barth KH,Lutz RJ,Kremers PW,Miller DL

更新日期：1988-07-01 00:00:00

abstract：:The Point Spread Function (PSF) in NMR imaging is the result of both the line broadening due to magnet field inhomogeneity and the intrinsic spectrum of the nucleus at resonance. In the case of proton imaging, the line broadening dominates the small chemical shifts and the spectral lines are not resolved. This is not ...

journal_title：Investigative radiology

authors： Harrison CG,Adams DF,Kramer PB

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the correlation between dynamic gadoxetic acid-enhanced magnetic resonance imaging parameters and specific uptake values (SUVs) derived from ¹⁸fluorodeoxyglucose (¹⁸F-FDG) and ⁶⁸Ga-DOTA-Tyr(3)-octreotate (⁶⁸Ga-DOTATATE) positron emission tomography/computed tomogra...

journal_title：Investigative radiology

authors： Armbruster M,Sourbron S,Haug A,Zech CJ,Ingrisch M,Auernhammer CJ,Nikolaou K,Paprottka PM,Rist C,Reiser MF,Sommer WH

更新日期：2014-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To summarize the chemical synthesis, physicochemical characterization, pharmacokinetic behavior, and biological evaluation of P743, a new macromolecular iodinated contrast medium. METHODS:The synthesis and molecular modeling of the iodinated macromolecule P743 are described. The pharmacokineti...

journal_title：Investigative radiology

authors： Idée JM,Port M,Robert P,Raynal I,Prigent P,Dencausse A,Le Greneur S,Tichkowsky I,Le Lem G,Bourrinet P,Mugel T,Benderbous S,Devoldere L,Bourbouze R,Meyer D,Bonnemain B,Corot C

更新日期：2001-01-01 00:00:00

abstract：:Early detection of pancreatic ductal adenocarcinoma (PDAC) represents the most significant step toward the treatment of this aggressive lethal disease. Previously, we engineered a preclinical Thy1-targeted microbubble (MBThy1) contrast agent that specifically recognizes Thy1 antigen overexpressed in the vasculature of...

journal_title：Investigative radiology

authors： Bam R,Daryaei I,Abou-Elkacem L,Vilches-Moure JG,Meuillet EJ,Lutz A,Marinelli ER,Unger EC,Gambhir SS,Paulmurugan R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Imaging of the kidney using blood oxygen level dependent MR presents a major opportunity to examine differences in tissue oxygenation within the cortex and medulla applicable to human disease. We sought to define the differences between regions within kidneys and to optimize selection of regions of interest ...

journal_title：Investigative radiology

authors： Gloviczki ML,Glockner J,Gomez SI,Romero JC,Lerman LO,McKusick M,Textor SC

更新日期：2009-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00

abstract：:Left ventricular volume has been measured with ultrafast computed tomography. However, the accuracy with which this can be done is unknown. We therefore imaged with ultrafast computed tomography 11 rectangular phantoms, 20 to 225 ml, and 17 left ventricular casts, 15 to 112 ml. Two observers planimetered serial tomogr...

journal_title：Investigative radiology

authors： Pietras RJ,Wolfkiel CJ,Veselik K,Roig E,Chomka EV,Brundage BH

更新日期：1991-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A computerized system that applies the case-based approach to training radiologists to diagnose brain tumors was designed. The authors attempted to provide residents a tool that supports their visual memory and inducts case-based reasoning. METHODS:A relational database with a digital image li...

journal_title：Investigative radiology

authors： Macura RT,Macura KJ,Toro VE,Binet EF,Trueblood JH,Ji K

更新日期：1994-04-01 00:00:00

abstract：:The association of GE Medical Systems and the AUR represents a unique collaboration between academic radiology and industry that bears important potential for elevating the quality of clinical research in radiology and developing a cadre of high-quality radiologist researchers for the future. The establishment of the ...

journal_title：Investigative radiology

authors： Hillman BJ,Fryback DG,Holden RW,McNeil BJ,Molitor RM,Moss AA,Peck PV,Putman CE,Thompson WM

更新日期：1993-05-01 00:00:00

abstract：:Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

journal_title：Investigative radiology

authors： Cuttino JT Jr,Goss FU,Clark RL,Marr MC

更新日期：1981-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate the capacity of manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging (MRI) to discriminate the injured myocardium from the normal myocardium in a cat model. MATERIALS AND METHODS:Fourteen cats were prepared for acute myocardial infarction with 90-minute...

journal_title：Investigative radiology

authors： Kim TH,Yang DH,Choi JW,Kim ST,Yoon JH,Shin JH,Seo JB,Gong GY,Lim TH

更新日期：2005-01-01 00:00:00

abstract：:Because of the strong scientific evidence in support of radiation hormesis, we can no longer ignore this concept. There is, however, need for additional, carefully documented investigations in selected biological systems exposed to LLIR if the matter of radiation hormesis is to be settled once and for all. This need s...

journal_title：Investigative radiology

authors： Loken MK,Feinendegen LE

更新日期：1993-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

journal_title：Investigative radiology

authors： Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

更新日期：1993-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...

journal_title：Investigative radiology

authors： Lawaczeck R,Diekmann F,Diekmann S,Hamm B,Bick U,Press WR,Schirmer H,Schön K,Weinmann HJ

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS:Twenty patients with known or suspected focal liver lesions underwent liver MRI usi...

journal_title：Investigative radiology

authors： Zech CJ,Herrmann KA,Dietrich O,Horger W,Reiser MF,Schoenberg SO

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to analyze the effect of dual-energy computed tomography (DECT) scanners and fluid characteristics on iodine quantification and to calculate the measurement variability range induced by those variables. METHODS:We performed an experimental phantom study with 4 mediastinal iodine ...

journal_title：Investigative radiology

authors： Kim H,Goo JM,Kang CK,Chae KJ,Park CM

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to assess the feasibility of magnetic resonance cholangiography (MRC) using biliary-secreted gadoxetic acid at 7 T and to compare it with T2-weighted (w) MRC at 3 T. MATERIALS AND METHODS:Ten healthy volunteers were examined on a 7-T whole-body magnetic resonance system. T2...

journal_title：Investigative radiology

authors： Fischer A,Kraff O,Orzada S,Nensa F,Schäfer LC,Ladd ME,Umutlu L,Lauenstein TC

更新日期：2014-05-01 00:00:00

abstract：:The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...

journal_title：Investigative radiology

authors： Cox GG,Templeton AW,Anderson WH,Cook LT,Hensley KS,Dwyer SJ 3rd

更新日期：1986-02-01 00:00:00

abstract：:The large intestines of eight boxer dogs with canine histiocytic ulcerative colitis (CHUC) and 10 normal dogs were studied by in vivo angiography and postmortem microangiography. The vascular abnormalities were correlated with the gross and histologic pathology found at necropsy. The angiographic abnormalities were ...

journal_title：Investigative radiology

authors： Lawson TL,Gomez JA,Margulis AR

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF) has been related to the use of gadolinium-based contrast agents (GBCAs) in patients undergoing dialysis. The Prospective Fibrose Nephrogénique Systémique study, a French prospective study supported by the French drug regulatory agency (Agence Nationale de Sécurité du Médic...

journal_title：Investigative radiology

authors： Amet S,Launay-Vacher V,Clément O,Frances C,Tricotel A,Stengel B,Gauvrit JY,Grenier N,Reinhardt G,Janus N,Choukroun G,Laville M,Deray G

更新日期：2014-02-01 00:00:00

abstract：:The rates at which the paramagnetic compounds deoxyhemoglobin (Hb) and methemoglobin (MHb) form in vivo within an area of hemorrhage are unknown. The present experiment establishes the baseline concentrations and rates of change in paramagnetic hemoglobin concentrations, as well as the pH in normal heparinized and clo...

journal_title：Investigative radiology

authors： Taber KH,Migliore PJ,Pagani JJ,Ford JJ,McLauren T,Hayman LA

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to optimize computed tomography (CT) surveillance of skeletal metastases in patients with breast cancer through the use of osseous subtraction maps between baseline and follow-up examinations created by a novel software algorithm. The new postprocessing algorithm segments the origina...

journal_title：Investigative radiology

authors： Horger M,Thaiss WM,Wiesinger B,Ditt H,Fritz J,Nikolaou K,Kloth C

更新日期：2017-02-01 00:00:00

abstract：:Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...

journal_title：Investigative radiology

authors： Putman CE,Frank JA

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the impact of a novel iterative denoising and image enhancement technique in T1-weighted precontrast and postcontrast volume-interpolated breath-hold examination (VIBE) of the abdomen on image quality, noise levels, and diagnostic confidence without change of acquisit...

journal_title：Investigative radiology

authors： Gassenmaier S,Afat S,Nickel D,Kannengiesser S,Herrmann J,Hoffmann R,Othman AE

更新日期：2020-11-18 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...

journal_title：Investigative radiology

authors： Quattrocchi CC,Errante Y,Mallio CA,Marinelli L,LoVullo G,Giannotti G,Della Sala SW,van der Molen AJ,Beomonte Zobel B

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:We sought to assess large bowel motility, induced by 2 prokinetic agents, senna tea and erythromycin, using functional cine magnetic resonance imaging (MRI). MATERIALS AND METHODS:Twelve volunteers underwent functional cine MRI before and after the administration of senna tea or erythromycin. The protocol c...

journal_title：Investigative radiology

authors： Buhmann S,Kirchhoff C,Wielage C,Mussack T,Reiser MF,Lienemann A

更新日期：2005-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

journal_title：Investigative radiology

authors： Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00