Abstract:
OBJECTIVES:The aim of this study was to investigate the impact of a novel iterative denoising and image enhancement technique in T1-weighted precontrast and postcontrast volume-interpolated breath-hold examination (VIBE) of the abdomen on image quality, noise levels, and diagnostic confidence without change of acquisition parameters. MATERIALS AND METHODS:Fifty patients were included in this retrospective, monocentric, institutional review board-approved study after clinically indicated magnetic resonance imaging of the abdomen including T1-weighted precontrast and postcontrast imaging. After acquisition of the standard VIBE (VIBES), images were processed with a novel reconstruction algorithm using the same raw data as for VIBES, resulting in a denoised and enhanced dataset (VIBEDE). Two different radiologists evaluated both datasets in a randomized order regarding sharpness of organs as well as vessels, noise levels, artifacts, overall image quality, and diagnostic confidence using a Likert scale ranging from 1 to 4 with 4 being the best. Furthermore, in the presence of focal liver lesions, the largest lesion was measured in the postcontrast dataset, and lesion detectability was analyzed using a Likert scale (1-4). RESULTS:Precontrast and postcontrast sharpness of organs and sharpness of vessels were rated significantly superior by both readers in VIBEDE with a median of 4 (interquartile range, 0) compared with VIBES with a median of 3 (1) (all P's < 0.0001). Precontrast and postcontrast noise levels were also rated superior by both readers in VIBEDE with a median of 4 (0) compared with VIBES with a median of 3 (1) for precontrast and a median of 3 (0) (median of 3 [1] for reader 2) for postcontrast imaging (all P's < 0.0001).Overall image quality was also rated higher with a median of 4 (0) in VIBEDE versus 3 (1) in VIBES (P < 0.0001). Twenty-seven imaging studies contained liver lesions. There was no difference regarding the number and localization between the readers and between VIBES and VIBEDE. Lesion detectability was rated by both readers significantly better in VIBEDE with a median of 4 (0) compared with a median of 4 (1) for reader 1 and a median of 3 (1) for reader 2 (P = 0.001 for reader 1; P < 0.001 for reader 2). Consequently, diagnostic confidence was also significantly superior in VIBEDE versus VIBES with a median of 4 (0) for both (P = 0.001). Interreader agreement resulted in a Cohen κ of 0.76 for precontrast analysis as well as of 0.76 for postcontrast analysis. CONCLUSIONS:Application of a novel iterative denoising and image enhancement technique in T1-weighted VIBE precontrast and postcontrast imaging of the abdomen is feasible, providing superior image quality, noise levels, and diagnostic confidence.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Gassenmaier S,Afat S,Nickel D,Kannengiesser S,Herrmann J,Hoffmann R,Othman AEdoi
10.1097/RLI.0000000000000746subject
Has Abstractpub_date
2020-11-18 00:00:00eissn
0020-9996issn
1536-0210pub_type
杂志文章abstract:OBJECTIVES:Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41°C-43°C) in deep-seated tissues. Magnetic Resonance (MR) imaging provides therapy planning on anatomical i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000392
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:Altered systolic blood flow in the ascending aorta has been correlated with increased aortic growth in patients with bicuspid aortic valves (BAVs). We used conventional, 2-dimensional (2D) phase contrast magnetic resonance imaging (PC-MRI) to assess the relationship between altered flow and future growth in ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000064
更新日期:2014-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 9...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199404000-00010
更新日期:1994-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors differentiate acute tubular necrosis from transplant rejection in patients with delayed kidney graft function using gadolinium (Gd)-DTPA enhanced magnetic resonance (MR) imaging. METHODS:Twenty-four patients after renal transplantation (10 with normal graft function, 14 with delaye...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/00004424-199606000-00009
更新日期:1996-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The relative stability and selectivity of magnetic resonance (MR) imaging contrast agents were compared with in vitro transmetallation and ligand competition reactions. MATERIALS AND METHODS:A gadolinium (Gd)-DTPA-BIGA, Gd-DTPA-BMA, Gd-DTPA, or Gd-HP-DO3A solution was mixed with an equimolar s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199610000-00003
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000167421.83203.4e
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVES:The authors assessed the relative efficacy of conventional and digital storage-phosphor radiographs for the detection of skull fractures. METHODS:Fifty conventional film-screen radiographs (FSR) and 50 digital storage-phosphor radiographs (DR) with 66 fractures were compared. Five radiologists evaluated ima...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199308000-00005
更新日期:1993-08-01 00:00:00
abstract::The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198602000-00014
更新日期:1986-02-01 00:00:00
abstract::A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours be...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/00004424-198809001-00035
更新日期:1988-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS:Recordings were obtai...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199612000-00007
更新日期:1996-12-01 00:00:00
abstract::Breast calcification diagnosis was studied by using clinical findings and computerized image processing of a mammogram in a network of trained expert learning systems (Outcome Advisor [OA]). The system was tested with records not used for training and performance was compared with radiologist. The network was 72% accu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199106000-00004
更新日期:1991-06-01 00:00:00
abstract::The morphologic changes in healthy rat kidneys (n = 102) were studied 2 or 48 hours after intravenous injection of 1 or 3 g iodine (I)/kg of high-osmolality diatrizoate, low-osmolality iopromide and iohexol, or iso-osmolality iotrolan, as well as after 0.2 or 0.6 g/kg of the high-osmolality magnetic resonance contrast...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199110000-00009
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...
journal_title:Investigative radiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/RLI.0000000000000058
更新日期:2014-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To assess whether differences in cerebral atrophy and white matter lesions or in the presence of lactate and lipid signals can explain the observed differences in brain choline, creatine, and N-acetylaspartate levels between healthy elderly women and men. METHODS:In addition to standard magnet...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200110000-00005
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVES:Comparison of intravenous Fenestra VC-enhanced computed tomography (CT) with gadopentetate dimeglumine and Ferucarbotran contrast-enhanced magnetic resonance imaging (MRI) for the in vivo imaging of hepatic ischemia/reperfusion injury (IRI) in a murine model. MATERIAL AND METHODS:After induction of hepatic ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318155aa2e
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:Thermal dose in tumor tissue is a key factor for regional hyperthermia (HT) combined with chemotherapy and for drug delivery using thermosensitive liposomes (TSL). It influences therapy outcome, affects the accumulation of liposomes, and triggers the content release from TSL in the target tissue. For the dev...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31818768cd
更新日期:2008-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the feasibility of mechanical thrombectomy in occluded hemodialysis access shunts by using a newly developed 5F pigtail rotation catheter. METHODS:Thrombosed hemodialysis access shunts were simulated by clotted bovine blood in silicone tubing (diameter 6 mm). After retrograde and a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199907000-00008
更新日期:1999-07-01 00:00:00
abstract::The cytogenetic interactions of ionic (diatrizoate, ioxaglate) and nonionic (iohexol) contrast media (CM) with antineoplastic drugs cyclophosphamide (CPA) and carmustine (CARM) were evaluated in a rat bone marrow cell model. Male Wistar rats were anesthetized with a 6% chloral hydrate solution and divided into five gr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198805000-00011
更新日期:1988-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Air microemboli may damage the cerebral microvasculature. The aim of this study was to evaluate the safety of ultrasound contrast agents composed of air microspheres with regard to cerebral damage when administered into the arterial system (ie, when not filtered by the capillary system of the l...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199803000-00001
更新日期:1998-03-01 00:00:00
abstract::Ionic (diatrizoate, ioxaglate) and nonionic (iohexol, iosimide, iopromide, and iotrolan) contrast media (CM) were evaluated for their cytogenetic effects in lymphocytes. Heparinized blood was mixed with culture medium RPMI-1640 supplemented with phytohemagglutinin, fetal calf serum, and antibiotics. Plastic tubes cont...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198611000-00006
更新日期:1986-11-01 00:00:00
abstract::A feasibility study is described to provide quantitative texture measures to distinguish between normal lung, alveolar infiltrates and interstitial infiltrates. Advanced computer imaging technology and decision making processes were applied to distinguish between these textural patterns. The results, based on computer...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197807000-00005
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to test the feasibility of an investigational dual-channel next-generation endorectal coil (NG-ERC) in vivo, to quantitatively assess signal-to-noise ratio (SNR), and to get an impression of image quality compared with the current clinically available single-loop endorectal ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182a56678
更新日期:2014-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199706000-00006
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the prognostic utility of a staging system using magnetic resonance imaging (MRI) with the seventh American Joint Committee on Cancer (AJCC) staging system in patients with hepatocellular carcinoma (HCC) who underwent hepatic resection. MATERIALS AND METHODS:A total of 1...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182630e8d
更新日期:2012-11-01 00:00:00
abstract::Blood samples from previous contrast reactors and nonreactor controls were incubated with diatrizoate and several contrast analogues. Total complement levels were assayed. All the agents caused complement activation generally proportional to their concentration. Reactors' sera responded to lower concentrations of cont...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198307000-00018
更新日期:1983-07-01 00:00:00
abstract::The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199010000-00007
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVES:The aim of this pilot study was to assess post-treatment apparent diffusion coefficient (ADC) changes of diffuse large B-cell lymphoma lesions on respiratory-gated whole-body diffusion-weighted imaging (DWI), with integrated (18)F-fluoro-2-deoxyglucose positron emission tomography/computed tomography (PET/CT...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182087b03
更新日期:2011-05-01 00:00:00
abstract::Groups of 5 fasting male and female patients aged 32-83 years were each given 3 gm of the cholecystographic contrast medium iosumetic acid in micronized form (particle size less than 20 mum); Group I with 150 ml tea (standard administration); Group II with 500 ml tea; Group III with 150 ml tea plus 10 mg metocloprami...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197607000-00009
更新日期:1976-07-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to analyze the effect of dual-energy computed tomography (DECT) scanners and fluid characteristics on iodine quantification and to calculate the measurement variability range induced by those variables. METHODS:We performed an experimental phantom study with 4 mediastinal iodine ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000446
更新日期:2018-06-01 00:00:00
abstract::The authors investigated the effect on the brain of red blood cells that had been modified by contrast media. Rat blood was mixed with an equivolume of contrast media, and up to 200 microL of the mixture was infused to the internal carotid artery of the rat. Evans blue was administered intravenously to assess the inte...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198905000-00009
更新日期:1989-05-01 00:00:00