Abstract:
RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation and nine healthy volunteers underwent MR imaging. Twenty-five subsecond contrast-enhanced MR images (turbo-fast low-angle shot [FLASH]) were obtained at the level of the pulmonary arteries after a single injection of gadopentetate dimeglumine (0.1 mmol/kg) in an antecubital vein. Perfusion lung scintigraphy was done within 24 hours after the MR imaging examination in the transplanted patients. RESULTS:Before administration of contrast material, MR images showed both lungs to be homogeneous and of low signal intensity in healthy controls and in patients with lung transplantation. After contrast administration in controls, the mean signal intensity of the dependent lung increased markedly to 171 +/- 24% above baseline, whereas the nondependent signal intensity lung increased by only 105 +/- 17%; these changes were significantly different. In all patients with lung transplantation, a clear perfusion defect was demonstrated in the native lung. This defect was confirmed in all cases by perfusion nuclear scintigraphy, which showed that the majority of lung perfusion is directed to the transplanted allograft, compared with the native contralateral lung. CONCLUSIONS:Our results suggest that dynamic contrast-enhanced MR imaging is a potential method for detecting pulmonary perfusion defects in patients with lung transplantation.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Berthezène Y,Croisille P,Bertocchi M,Houzard C,Bendib K,Revel Ddoi
10.1097/00004424-199706000-00006subject
Has Abstractpub_date
1997-06-01 00:00:00pages
351-6issue
6eissn
0020-9996issn
1536-0210journal_volume
32pub_type
杂志文章abstract::We evaluated the incidence of ventricular fibrillation with low-osmolality contrast media by right coronary arteriography in eleven adult mongrel dogs. Following insertion of the catheter into the right coronary artery, a test solution was infused for 25 seconds (total 11 mL) or until fibrillation occurred. The test s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198904000-00008
更新日期:1989-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare power versus manual injection in bolus shape and image quality on contrast-enhanced magnetic resonance angiography (CE-MRA). MATERIALS AND METHODS:Three types of CE-MRA (head-neck 3-dimensional [3D] MRA with a test-bolus technique, thoracic-abdominal 3D MRA with a bolus-t...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000383
更新日期:2017-09-01 00:00:00
abstract::A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198307000-00009
更新日期:1983-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study sought to evaluate prospectively the diagnostic potential of unenhanced and enhanced color Doppler and power Doppler for the differentiation of tumors and tumorlike lesions of the breast. METHODS:Ninety-two patients with 110 tumors or tumorlike lesions of the breast were investigate...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199902000-00003
更新日期:1999-02-01 00:00:00
abstract::Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198507000-00009
更新日期:1985-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors determine the value of contrast-enhanced, three-dimensional (3D) magnetic resonance angiography (MRA) in the assessment of the renal arteries in comparison with conventional arteriography (CA). METHODS:One hundred three patients (71 m, 32 f) were evaluated with both CA and 3D MRA. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199809000-00021
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the ability of a flow-sensitive alternating inversion recovery-arterial spin labeling (FAIR-ASL) technique to track renal perfusion changes during pharmacologic and physiologic alterations in renal blood flow using microspheres as a gold standard. MATERIALS AND METHODS...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181f5e101
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVES:To determine the impact of slice thickness on semiautomatic lymph node analysis. MATERIALS AND METHODS:Thoracic multislice computed tomography (MSCT) of 46 patients with NSCLC were reconstructed at 1.0-, 3.0-, and 5.0-mm slice thickness. Two radiologists independently determined long and short axis diameter...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181c443e1
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:: To evaluate the performance of a gadolinium-based contrast compound (P846) as well as an ultra-small particle of iron oxide agent (P904) in contrast-enhanced magnetic resonance angiography (MRA) in rabbits and to compare those agents with gadoterate meglumine (Gd-DOTA) for first pass and steady state imagi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31821ae21f
更新日期:2011-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Ureteric jet index (UJI), a newly developed technique derived from color Doppler ultrasonography, may hold promise in evaluating renal function because of its ability to evaluate individual renal function and the use of nonionizing radiation. To assess the usefulness of UJI, the authors in this...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199908000-00001
更新日期:1999-08-01 00:00:00
abstract::Observation of the relaxivity of MRI contrast media over a wide range of magnetic fields is not only necessary for predicting their efficiency at any field but also compulsory for understanding and improving their mechanisms of action. The best experimental approach to this problem is the field cycling method, which a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00047
更新日期:1988-09-01 00:00:00
abstract::A double-blind randomized study of ten patients compared Hexabrix 32% to Renografin-60 in TMJ arthrography. Equivalent volumes of contrast material were injected under fluoroscopic observation, with film quality and patient subjective response graded independently by three radiologists. In immediate arthrogram quality...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/00004424-198411001-00032
更新日期:1984-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Low-field magnetic resonance imaging (MRI) evaluation of breast implants is described, with emphasis on the capabilities provided by different imaging sequences. METHODS:Open architecture MR images using a .064-T permanent magnet and three-dimensional Fourier transform and inversion recovery s...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199408000-00009
更新日期:1994-08-01 00:00:00
abstract::The contrast sensitivity of the retina is greatest in the center and decreases rapidly toward the periphery. Therefore, the detection of low-contrast lung nodules depends upon the manner in which the image is sampled by retinal receptors as eye fixations jump across the image during scanning. The scanning performance ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198705000-00010
更新日期:1987-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the role of granulocytes in reperfusion injury after liver transplantation. The authors injected radiolabeled granulocytes to determine if human liver graft outcome could be correlated with granulocyte accumulation. MATERIALS AND METHODS:Pure granulocyte suspension was prepared fro...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199603000-00003
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:To determine whether time-resolved magnetic resonance angiography (TR-MRA) with ultra-low-dose gadolinium chelate (1.5-3.0 mL) can reliably detect or rule out hemodynamically significant disease in the carotid-vertebral artery territory. MATERIALS AND METHODS:Hundred consecutive patients (62 women, 38 men, mea...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31819ca048
更新日期:2009-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The objective of the present study was to compare the data regarding the ability of real-time myocardial contrast echocardiography (MCE) to assess altered myocardial blood flow produced by graded coronary stenoses between open- and closed-chest canine models. MATERIALS AND METHODS:Three grades...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200301000-00006
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To evaluate the diagnostic performance of 1.0-M gadobutrol-enhanced, 3-dimensional (3D), dynamic MR images with 3D-MR cholangiography (MRC) in the preoperative evaluation of bile duct cancer staging and resectability. MATERIALS AND METHODS:Our institutional review board approved this retrospective study. Sixty...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181d2eeb1
更新日期:2010-04-01 00:00:00
abstract::Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198105000-00016
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318243e062
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b66d11
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare a compressed-sensing free-breathing VIBE (fbVIBE) with a conventional breath-hold VIBE (bhVIBE) for dynamic contrast-enhanced imaging of the upper abdomen. MATERIALS AND METHODS:In total, 70 datasets (bhVIBE, n = 30; fbVIBE n = 40; hard-gated [hg] reconstruction, n = 30;...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000607
更新日期:2019-11-01 00:00:00
abstract::Prior to the formation of an intravenous digital subtraction angiography (IV-DSA) image, contrast medium passes through the lesser circulation and is diluted by the blood volume of the heart and lungs. If the contrast medium alone influences central blood volume or cardiac output, the shape of the resultant time-conce...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198603000-00009
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000285
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Bolus injection of iodinated contrast media has been observed to alter myocardial mechanical function, but the consequences on cellular metabolism are poorly documented. Modifications of metabolic parameters (intracellular pH as well as adenosine triphosphate [ATP], phosphocreatine, and inorgan...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199501000-00001
更新日期:1995-01-01 00:00:00
abstract::Breast calcification diagnosis was studied by using clinical findings and computerized image processing of a mammogram in a network of trained expert learning systems (Outcome Advisor [OA]). The system was tested with records not used for training and performance was compared with radiologist. The network was 72% accu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199106000-00004
更新日期:1991-06-01 00:00:00
abstract:PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000167421.83203.4e
更新日期:2005-07-01 00:00:00
abstract::An isotopic radiation source 125I was investigated for use in soft tissue radiaography, with particular attention to possible use in mammography for mass screening. Film sensitivities, exposure rates, absorbed doeses, contrast and resolution were determined, and compared to conventional x-ray units. It was found that ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197509000-00007
更新日期:1975-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the impact on metal artifacts and dose efficiency of using a tin filter in combination with high-energy threshold (TH) images of a photon-counting detector (PCD) computed tomography (CT) system. MATERIALS AND METHODS:A 3D-printed spine with pedicle screws was scanned...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000535
更新日期:2019-04-01 00:00:00
abstract::Gadolinium was attached to antibodies and tested in vitro and in vivo for its effect on proton relaxation enhancement. Using the cyclic anhydride method, diethylenetriaminepentaacetic acid (DTPA) was attached to albumin, IgG and anti-CEA monoclonal antibody. Gadolinium (Gd) was then chelated to the protein complexes f...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198510000-00008
更新日期:1985-10-01 00:00:00