Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions.

Abstract:

OBJECTIVES:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS:Twenty patients with known or suspected focal liver lesions underwent liver MRI using a DW-EPI sequence with a b-value of 50 S/mm2 (TR/TE 2200/50 ms) and a standard fat-saturated T2-w sequence (TR/TE 2800/107 ms) with 6-mm slice thickness on a 1.5-T MRI system. Both sequences used parallel imaging with an acceleration factor of 2. Overall image quality and degree of artifacts were compared on a 5-point scale with 5 being the most desirable score. The detection rate and the level of confidence with regard to lesion detection were evaluated for both sequences in comparison to a contrast-enhanced (Gadolinium and SPIO) MR examination, which was used as the standard of reference. RESULTS:The DW-EPI sequence showed significantly (P < 0.05) improved overall image quality (average score 4.15 vs. 3.63) and fewer artifacts (average score 4.2 vs. 3.5) in comparison with the T2-w sequence. The sensitivity for lesion detection was superior in the DW-EPI sequence (83% vs. 61%). The level of confidence in the detection of focal liver lesions was also superior for the DW-EPI sequence in comparison with the T2-w sequence (average score 3.9 vs. 3.2). CONCLUSIONS:DW-EPI sequences for liver-imaging are feasible with parallel imaging and show excellent image quality. They may contribute to more easy and confident lesion detection in comparison with T2-w sequences.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Zech CJ,Herrmann KA,Dietrich O,Horger W,Reiser MF,Schoenberg SO

doi

10.1097/RLI.0b013e31816200b5

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

261-6

issue

4

eissn

0020-9996

issn

1536-0210

pii

00004424-200804000-00007

journal_volume

43

pub_type

杂志文章
  • Effects of angiographic needle size and subsequent catheter insertion on arterial walls. An in vitro experiment in human cadavers.

    abstract:RATIONALE AND OBJECTIVES:It is widely believed that down-sizing catheters, and possibly needles, will decrease damage to the entry vessel in the performance of angiography. The purposes of this in vitro experiment are to determine if smaller needles produce less arterial wall damage than larger needles and to assess th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199210000-00001

    authors: Smith DC,Hamlin JA,Jensen DA,Pappas JM,Westengard JC,Saukel GW

    更新日期:1992-10-01 00:00:00

  • Low tube voltage improves computed tomography imaging of delayed myocardial contrast enhancement in an experimental acute myocardial infarction model.

    abstract:OBJECTIVE:We sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (MI) in cardiac multislice spiral computed tomography (MSCT). MATERIALS AND METHODS:Acute MI was induced in 12 domestic pigs by a 45-minute balloon occlusion of the left anterior descending artery. Delayed...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000251577.68223.84

    authors: Mahnken AH,Bruners P,Mühlenbruch G,Emmerich M,Hohl C,Günther RW,Wildberger JE

    更新日期:2007-02-01 00:00:00

  • Hardcopy recording technologies for digitally formatted image data.

    abstract::The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199102000-00017

    authors: Siegel EL,Bishop MD,Wetzel LH,Anderson WF,McMillan JH

    更新日期:1991-02-01 00:00:00

  • Three-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: initial results using highly accelerated parallel acquisition.

    abstract:OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.rli.0000236992.21065.04

    authors: Nael K,Fenchel M,Salamon N,Duckwiler GR,Laub G,Finn JP,Villablanca JP

    更新日期:2006-10-01 00:00:00

  • Facilitated Diagnosis of Pneumothoraces in Newborn Mice Using X-ray Dark-Field Radiography.

    abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000285

    authors: Hellbach K,Yaroshenko A,Willer K,Pritzke T,Baumann A,Hesse N,Auweter S,Reiser MF,Eickelberg O,Pfeiffer F,Hilgendorff A,Meinel FG

    更新日期:2016-10-01 00:00:00

  • Diagnostic performance of dark-blood T2-weighted CMR for evaluation of acute myocardial injury.

    abstract:OBJECTIVES:We compared the image quality and diagnostic performance of 2 fat-suppression methods for black-blood T2-weighted fast spin-echo (FSE), which are as follows: (a) short T1 inversion recovery (STIR; FSE-STIR) and (b) spectral adiabatic inversion recovery (SPAIR; FSE-SPAIR), for detection of acute myocardial in...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182718672

    authors: Srichai MB,Lim RP,Lath N,Babb J,Axel L,Kim D

    更新日期:2013-01-01 00:00:00

  • Potential of dose reduction after marker placement with full-field digital mammography.

    abstract:OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000163743.63063.9f

    authors: Riedl CC,Jaromi S,Floery D,Pfarl G,Fuchsjaeger MH,Helbich TH

    更新日期:2005-06-01 00:00:00

  • Clinical image quality assessment of accelerated magnetic resonance neuroimaging using compressed sensing.

    abstract:PURPOSE:The aim of this study was to determine to what degree current compressed sensing methods are capable of accelerating clinical magnetic resonance neuroimaging sequences. METHODS:Two 2-dimensional clinical sequences were chosen for this study because of their long scan times. A pilot study was used to establish ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31828a012d

    authors: Sharma SD,Fong CL,Tzung BS,Law M,Nayak KS

    更新日期:2013-09-01 00:00:00

  • New contrast media in cerebral angiography: animal experiments and preliminary clinical studies.

    abstract::The cerebrovascular toxicity of three water-soluble contrast agents with a low hypertonicity (metrizamide, ioxaglate, iopamidol) was tested. Blood-brain barrier damage after carotid injection was assessed using 32P autoradiography and fluorescent microscopy after Evans blue staining. The damage to carotid endothelium ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198011001-00058

    authors: Gonsette RE,Liesenborgh L

    更新日期:1980-11-01 00:00:00

  • Combined methods for assessment of neurotoxicity: testing of new nonionic radiographic media.

    abstract::A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198011001-00053

    authors: Sovak M,Siefert HM,Ranganathan R

    更新日期:1980-11-01 00:00:00

  • Computed tomography of the normal radioulnar joints.

    abstract::Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198311000-00012

    authors: Cone RO,Szabo R,Resnick D,Gelberman R,Taleisnik J,Gilula LA

    更新日期:1983-11-01 00:00:00

  • Increased urine histamine and contrast media reactions.

    abstract::Urine samples were collected from 200 subjects undergoing intravenous pyelography. The urine histamine levels were compared with those of 132 normal control subjects, 11 subjects with systemic mastocytosis, six subjects with idiopathic anaphylaxis, and ten subjects experiencing mild anaphylactic reactions during aller...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198403000-00007

    authors: Kaliner M,Dyer J,Merlin S,Shelton A,Greenhill A,Treadwell G,McKenna W,Lieberman P

    更新日期:1984-03-01 00:00:00

  • The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy.

    abstract::Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198507000-00009

    authors: Dae M,Canhasi B,Botvinick E,Olvera S,Schechtmann N,Engelstad B,Hattner R,Schiller N,O'Connell W,Faulkner D

    更新日期:1985-07-01 00:00:00

  • Differentiation of breast lesions by measurements under craniocaudal and lateromedial compression using a new sonographic method.

    abstract:RATIONALE AND OBJECTIVES:The authors differentiate breast lesions on sonography by measurements in two compression states that are perpendicular to each other. METHODS:Diameters of 100 breast lesions were measured preoperatively under lateromedial and craniocaudal compression with a new sonographic method. This method...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199607000-00003

    authors: Richter K,Willrodt RG,Opri F,Heywang-Köbrunner SH

    更新日期:1996-07-01 00:00:00

  • Breast stereotactic core biopsy washings: abundant cell samples from clinically occult lesions for flow cytometric DNA analysis.

    abstract:RATIONALE AND OBJECTIVES:The object of this study was to determine by flow cytometry the cellular and DNA content of the washings of core biopsy samples and needles obtained during stereotactic core biopsies of clinically occult suspicious lesions. METHODS:Fourteen-gauge core multipass biopsy inner-needle saline washi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199801000-00008

    authors: Stomper PC,Budnick RM,Stewart CC

    更新日期:1998-01-01 00:00:00

  • MR characterization of mild hyperthermia-induced gadodiamide release from thermosensitive liposomes in solid tumors.

    abstract:OBJECTIVES:Thermal dose in tumor tissue is a key factor for regional hyperthermia (HT) combined with chemotherapy and for drug delivery using thermosensitive liposomes (TSL). It influences therapy outcome, affects the accumulation of liposomes, and triggers the content release from TSL in the target tissue. For the dev...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31818768cd

    authors: Peller M,Schwerdt A,Hossann M,Reinl HM,Wang T,Sourbron S,Ogris M,Lindner LH

    更新日期:2008-12-01 00:00:00

  • First-pass evaluation of myocardial output during dipyridamole stress using turbo-FLASH magnetic resonance imaging.

    abstract:RATIONALE AND OBJECTIVES:This study evaluated the value of dynamically enhanced fast low-angle shot (FLASH) magnetic resonance (MR) imaging in measuring cardiac output with and without dipyridamole pharmacological stress. METHODS:Ten subjects underwent rest and stress MR imaging. Rest images were acquired using electr...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199611000-00003

    authors: Tello R,Hartnell GG,Hill TC,Cerel A,Finn JP,Kamalesh M,Cohen M,Lewis S

    更新日期:1996-11-01 00:00:00

  • Estimating digital information throughput rates for radiology networks. A model.

    abstract::The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198602000-00014

    authors: Cox GG,Templeton AW,Anderson WH,Cook LT,Hensley KS,Dwyer SJ 3rd

    更新日期:1986-02-01 00:00:00

  • Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro.

    abstract:RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199510000-00006

    authors: Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

    更新日期:1995-10-01 00:00:00

  • Computed tomography-pathologic assessment of laser-induced necrosis in rat liver.

    abstract:RATIONALE AND OBJECTIVES:Interstitial laser photocoagulation (ILP) causes localized tissue necrosis. This study was performed to determine 1) whether the changes seen on computed tomography (CT) correspond to the necrosis pathologically, and 2) which CT technique best shows the necrosis. METHODS:Eighteen Wistar rats h...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199312000-00014

    authors: Amin Z,Thurrell W,Spencer GM,Harries SA,Grant WE,Bown SG,Lees WR

    更新日期:1993-12-01 00:00:00

  • Interleaved Mapping of Temperature and Longitudinal Relaxation Rate to Monitor Drug Delivery During Magnetic Resonance-Guided High-Intensity Focused Ultrasound-Induced Hyperthermia.

    abstract:OBJECTIVES:Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41°C-43°C) in deep-seated tissues. Magnetic Resonance (MR) imaging provides therapy planning on anatomical i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000392

    authors: Kneepkens E,Heijman E,Keupp J,Weiss S,Nicolay K,Grüll H

    更新日期:2017-10-01 00:00:00

  • T2-Weighted 4D Magnetic Resonance Imaging for Application in Magnetic Resonance-Guided Radiotherapy Treatment Planning.

    abstract:OBJECTIVES:The aim of this study was to develop and verify a method to obtain good temporal resolution T2-weighted 4-dimensional (4D-T2w) magnetic resonance imaging (MRI) by using motion information from T1-weighted 4D (4D-T1w) MRI, to support treatment planning in MR-guided radiotherapy. MATERIALS AND METHODS:Ten pat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000381

    authors: Freedman JN,Collins DJ,Bainbridge H,Rank CM,Nill S,Kachelrieß M,Oelfke U,Leach MO,Wetscherek A

    更新日期:2017-10-01 00:00:00

  • Timing and magnitude of the postural effect on the distribution of pulmonary blood flow.

    abstract::The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198211000-00007

    authors: Kuribayashi S,Garnic JD,Abrams HL

    更新日期:1982-11-01 00:00:00

  • Brain tumor enhancement in magnetic resonance imaging: dependency on the level of protein binding of applied contrast agents.

    abstract:PURPOSE:To evaluate the dependency of tumor contrast enhancement (CE) in regard to protein-binding properties of contrast agents, using 4 different agents with a wide range of protein-binding capacities in a standardized rat brain glioma model. MATERIAL AND METHODS:Sixteen rats with implanted brain gliomas were evalua...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e318191a334

    authors: Wintersperger BJ,Runge VM,Tweedle MF,Jackson CB,Reiser MF

    更新日期:2009-02-01 00:00:00

  • Evaluation of postprocessing dual-energy methods in quantitative computed tomography. Part 2. Practical aspects.

    abstract::Three facets of dual-energy quantitative computed tomography are studied: (1) the algorithm for postprocessing data (the methods of Cann, Laval-Jeantet et al, Goodsitt et al [two methods], and Nickoloff et al); (2) the influence of choice of tissue-equivalent materials for calibration; and (3) the difference between c...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199008000-00003

    authors: van Kuijk C,Grashuis JL,Steenbeek JC,Schütte HE,Trouerbach WT

    更新日期:1990-08-01 00:00:00

  • Solid, part-solid, or non-solid?: classification of pulmonary nodules in low-dose chest computed tomography by a computer-aided diagnosis system.

    abstract:OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/RLI.0000000000000121

    authors: Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

    更新日期:2015-03-01 00:00:00

  • Degenerative disease of the sacroiliac joint.

    abstract::Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac oste...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197511000-00008

    authors: Resnick D,Niwayama G,Goergen TG

    更新日期:1975-11-01 00:00:00

  • Biodistribution of radiolabeled, formulated gadopentetate, gadoteridol, gadoterate, and gadodiamide in mice and rats.

    abstract:RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199506000-00008

    authors: Tweedle MF,Wedeking P,Kumar K

    更新日期:1995-06-01 00:00:00

  • Extravascular extravasation of radiographic contrast media. Effects of conventional and low-osmolar agents in the rat thigh.

    abstract::We compared the damage resulting from intradermal injection of four commonly used radiographic contrast media in laboratory rats. Sixty percent meglumine diatrizoate (Reno M 60) and ioxaglate (Hexabrix) produced significantly more ulceration and crusting on gross inspection and more necrosis, edema, and hemorrhage on ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199005000-00006

    authors: Cohan RH,Leder RA,Bolick D,Herzberg AJ,Hedlund LW,Wheeler CT,Helms MJ,Dunnick NR

    更新日期:1990-05-01 00:00:00

  • Contrast media-induced chromosomal damage in human lymphocyte cultures.

    abstract::Ionic (diatrizoate, ioxaglate) and nonionic (iohexol, iosimide, iopromide, and iotrolan) contrast media (CM) were evaluated for their cytogenetic effects in lymphocytes. Heparinized blood was mixed with culture medium RPMI-1640 supplemented with phytohemagglutinin, fetal calf serum, and antibiotics. Plastic tubes cont...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198611000-00006

    authors: Parvez Z,Kormano M,Moncada R,Eklund R

    更新日期:1986-11-01 00:00:00