High-resolution magnetic resonance imaging at 2 Tesla: potential for atherosclerotic lesions exploration in the apolipoprotein E knockout mouse.

abstract：:The interdisciplinary approach to medical education has often been deficient in medical school curricula. Because of the nonintegrated approach to medical education, problem solving capabilities are not fostered. The clinical presentation of a patient, the imaging modalities used to investigate the patient, and the ul...

journal_title：Investigative radiology

authors： Oldham SA,Jacobson F

更新日期：1986-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To study cellular mechanisms that cause contrast media nephropathy, an in vitro system for proximal and distal tubular cells has been established to evaluate the influence of x-ray contrast media on tubular function. METHODS:Confluent cell cultures of the two renal cell lines, proximal tubule ...

journal_title：Investigative radiology

authors： Andersen KJ,Christensen EI,Vik H

更新日期：1994-11-01 00:00:00

abstract：:Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented. ...

journal_title：Investigative radiology

authors： Enge I

更新日期：1985-01-01 00:00:00

abstract：:A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...

journal_title：Investigative radiology

authors： Powers TA,Rees RS,Bowen RD

更新日期：1983-07-01 00:00:00

abstract：:Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...

journal_title：Investigative radiology

authors： Dae M,Canhasi B,Botvinick E,Olvera S,Schechtmann N,Engelstad B,Hattner R,Schiller N,O'Connell W,Faulkner D

更新日期：1985-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Tissue contrast phenomenology was investigated analytically and clinically for a class of magnetic resonance (MR) pulse sequences we call large-tip-angle (LTA) spin-echo (SE) imaging. In comparison to traditional SE sequences (denoted 90 degrees-180 degrees-echo), the LTA sequence is of the for...

journal_title：Investigative radiology

authors： Elster AD,Provost TJ

更新日期：1993-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status...

journal_title：Investigative radiology

authors： Link TM,Bauer J,Kollstedt A,Stumpf I,Hudelmaier M,Settles M,Majumdar S,Lochmüller EM,Eckstein F

更新日期：2004-08-01 00:00:00

abstract：:Various water soluble contrast media (WSCM) were injected subcutaneously into 970 hind feet of 485 rats. Gross morphologic changes were seen after the injection and analyzed as a function of various physicochemical characteristics of WSCM. The WSCM of larger volume, higher osmolality, higher iodine content, and meglum...

journal_title：Investigative radiology

authors： Kim SH,Park JH,Kim YI,Kim CW,Han MC

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...

journal_title：Investigative radiology

authors： Hahn G,Sorge I,Gruhn B,Glutig K,Hirsch W,Bhargava R,Furtner J,Born M,Schröder C,Ahlström H,Kaiser S,Moritz JD,Kunze CW,Shroff M,Stokland E,Trnkova ZJ,Schultze-Mosgau M,Reif S,Bacher-Stier C,Mentzel HJ

更新日期：2009-12-01 00:00:00

abstract：:The authors conducted an observer performance study to compare breast lesion detection of conventional mammography (CM) with teleradiology (TE) transmitted mammograms. One hundred four abnormal, single-projection mammographic images were transmitted by teleradiology. Abnormalities included 11 cases with skin thickenin...

journal_title：Investigative radiology

authors： Fajardo LL,Yoshino MT,Seeley GW,Hunt R,Hunter TB,Friedman R,Cardenas D,Boyle R

更新日期：1990-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

journal_title：Investigative radiology

authors： Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

更新日期：1993-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...

journal_title：Investigative radiology

authors： Putman CM,Chaloupka JC,Kailasnath P,Alderman J

更新日期：1997-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...

journal_title：Investigative radiology

authors： Truax AL,Chandnani VP,Chacko AK,Gonzalez DM

更新日期：1997-03-01 00:00:00

abstract：:With the ongoing development of new contrast agents, questions develop concerning the cardiac effects of these drugs. We used the perfused rat heart model to investigate the effects on cardiac and coronary function of hypertonic ionic (sodium chloride) and nonionic (glucose) solutions and conventional and low osmolali...

journal_title：Investigative radiology

authors： Fleetwood G,Bettmann MA,Gordon JL

更新日期：1990-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The clinically most widely used devices (Porstmann-plug, Rashkind-umbrella, Botallooccluder) have inherent specific limitations (eg, transarterial approach, residual shunts, limited retrieval). The authors assess practicability, efficacy, and tissue reaction of the new retrievable transvenous p...

journal_title：Investigative radiology

authors： Grabitz RG,Schräder R,Sigler M,Seghaye MC,Dzionsko C,Handt S,Schneidt B,Von Bernuth G

更新日期：1997-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

journal_title：Investigative radiology

authors： Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

更新日期：1995-10-01 00:00:00

abstract：:For magnetic resonance, the established class of intravenous contrast media is the gadolinium-based contrast agents. In the 3 decades since initial approval, these have proven in general to be very safe for human administration. However, in 2006, a devastating late adverse reaction to administration of the less stable...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2017-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors detect activation in the auditory cortex during cochlear electrical stimulation in deaf patients using functional magnetic resonance (MR) imaging. METHODS:Stimulating electrode was inserted gently under local anesthesia close to the round window membrane of the cochlea in seven coc...

journal_title：Investigative radiology

authors： Berthezène Y,Truy E,Morgon A,Giard MH,Hermier M,Franconi JM,Froment JC

更新日期：1997-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:We investigated whether it is possible to investigate degenerative changes in human tissue on a sub-100-microm resolution scale not only on special high-field small-bore MR-microscopy systems but also on a 3T whole-body MR-scanner. METHODS:Spin-spin relaxation, proton density, and diffusion mi...

journal_title：Investigative radiology

authors： Berg A,Sailer J,Rand T,Moser E

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To evaluate the dependency of tumor contrast enhancement (CE) in regard to protein-binding properties of contrast agents, using 4 different agents with a wide range of protein-binding capacities in a standardized rat brain glioma model. MATERIAL AND METHODS:Sixteen rats with implanted brain gliomas were evalua...

journal_title：Investigative radiology

authors： Wintersperger BJ,Runge VM,Tweedle MF,Jackson CB,Reiser MF

更新日期：2009-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...

journal_title：Investigative radiology

authors： Benness G,Khangure M,Morris I,Warwick A,Burrows P,Vogler H,Weinmann HJ

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the degree of ischemic changes of the small intestine after arterial embolization of proximal or distal arteries with Gelfoam particles and coils in dogs. METHODS:Superselective arterial embolization in 18 dogs was performed using a coaxial catheter system. Gelfoam occlusion of the proximal level...

journal_title：Investigative radiology

authors： Han YM,Lee JM,Jin KY,Lee SY,Kim CS

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:To evaluate the technical feasibility of high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) with highly accelerated parallel acquisition at 3.0 T using a 32-channel phased array coil, and a high relaxivity contrast agent. MATERIALS AND METHODS:Ten adult healthy volunteers (5 men,...

journal_title：Investigative radiology

authors： Nael K,Fenchel M,Krishnam M,Finn JP,Laub G,Ruehm SG

更新日期：2007-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for magnetic resonance imaging of the liver. METHODS:The contrast agent Gd-BOPTA or Gd-DTPA was administered at a dose of 0.1 mmol/kg to 257 patients suspected of having malignant liver tumors. Dynamic phase ...

journal_title：Investigative radiology

authors： Kuwatsuru R,Kadoya M,Ohtomo K,Tanimoto A,Hirohashi S,Murakami T,Tanaka Y,Yoshikawa K,Katayama H

更新日期：2001-11-01 00:00:00

abstract：:Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...

journal_title：Investigative radiology

authors： LeWinter MM,Pavelec RS

更新日期：1982-09-01 00:00:00

abstract：UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...

journal_title：Investigative radiology

authors： Szapiro D,Ghaye B,Willems V,Zhang L,Albert A,Dondelinger RF

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific dif...

journal_title：Investigative radiology

authors： Maas MC,Litjens GJS,Wright AJ,Attenberger UI,Haider MA,Helbich TH,Kiefer B,Macura KJ,Margolis DJA,Padhani AR,Selnæs KM,Villeirs GM,Fütterer JJ,Scheenen TWJ

更新日期：2019-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To establish a pig model suitable for imitating pulmonary emboli to facilitate research in the diagnosis of pulmonary embolism. METHODS:Thirteen animals were anesthetized, mechanically ventilated, and subjected to pulmonary artery catheterization initiated from the right external jugular vein....

journal_title：Investigative radiology

authors： Amundsen T,Kvaerness J,Aadahl P,Waage A,Bjermer L,Odegård A,Haraldseth O

更新日期：2000-05-01 00:00:00

abstract：:Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

journal_title：Investigative radiology

authors： Gould RG

更新日期：1992-12-01 00:00:00

abstract：:Using simple surgical techniques, experimental carotid aneurysms are created which simulate some types of human berry aneurysms, both in hemodynamic and radiographic behavior. End to side anastomoses of an external jugular vein graft to the common carotid artery can be carried out by radiologic personnel with no forma...

journal_title：Investigative radiology

authors： Kerber CW,Buschman RW

更新日期：1977-03-01 00:00:00