Experimental tissue damage after subcutaneous injection of water soluble contrast media.

Abstract:

:Various water soluble contrast media (WSCM) were injected subcutaneously into 970 hind feet of 485 rats. Gross morphologic changes were seen after the injection and analyzed as a function of various physicochemical characteristics of WSCM. The WSCM of larger volume, higher osmolality, higher iodine content, and meglumine salts rather than sodium salts caused more severe tissue damage; younger rats showed more severe tissue damage by WSCM of high osmolality.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Kim SH,Park JH,Kim YI,Kim CW,Han MC

doi

10.1097/00004424-199006000-00011

subject

Has Abstract

pub_date

1990-06-01 00:00:00

pages

678-85

issue

6

eissn

0020-9996

issn

1536-0210

journal_volume

25

pub_type

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