Optimal injection protocol for CT evaluation during hepatic arterial infusion chemotherapy.

Abstract:

OBJECTIVE:As an imaging modality for follow-up during continuous or repeated hepatic arterial infusion chemotherapy using a hepatic intra-arterial indwelling catheter, the usefulness of CT while infusing contrast through the indwelling catheter (reservoir port) was examined. METHODS:Using reservoir ports implanted in eight patients with hepatic metastasis from colon cancer, radioisotope perfusion scintigraphy (RI), CT (three rates of infusion of contrast were used), and digital subtraction angiography (AG) were performed to compare the modalities' ability to visualize the intrahepatic and abnormal extrahepatic distributions. RESULTS:CT (infusion rate 0.1 mL/sec) was superior to AG and RI in terms of the ability to visualize intrahepatic distribution, particularly in small areas, and facilitated 3D delineation of the distribution. In evaluating extrahepatic distribution, CT also outperformed the other modalities. CONCLUSIONS:For imaging study follow-up during hepatic arterial infusion chemotherapy, CT proved to be more useful than conventional RI and AG.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Morimoto M,Satake M,Sekiguchi R,Haruno M,Moriyama N

doi

10.1097/00004424-199912000-00003

keywords:

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

744-50

issue

12

eissn

0020-9996

issn

1536-0210

journal_volume

34

pub_type

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